PROSTATE MOTION KILOVOLTAGE INTRAFRACTION IMAGES AND REAL-TIME TRACKING SOFTWARE

Kilovoltage Intrafraction Monitoring (KIM) is a novel method of localizing tumours during treatment. The KIM software takes 2D x-ray images with fiducial markers acquired during treatment and determines the 3D positions of those markers in real-time. Depending on a preset threshold (e.g. 3mm/5s), it is decided whether or not to switch off the treatment beam and perform a couch shift.


KIM Gating Software Installer

Please download the KIM Gating installer here.

If a login is required, please use:
login: radphyslab@outlook.com or radphyslab2@outlook.com
password: kimgating3/5

WARNING: THIS SOFTWARE IS NOT FOR HUMAN USE. DEMO PURPOSES ONLY!


Running KIM Gating

After installing KIM Gating to an appropriate folder (e.g. KIM Gating), follow these instructions to run it:

KIM Gating Settings

Figure 1: KIM Gating software settings screen.

KIM Gating Settings Description

Table 1: Description of parameters on the KIM Gating software settings screen.

  1. Double-click RNSHProstateUI.exe in the KIM Gating folder and you will see the KIM Gating software settings screen in Figure 1.
  2. A detailed description of each parameter is provided in Table 1.
  3. Select the Source i.e. the operating mode.
  4. Select the directory of the images you would like to process.
  5. Input the required field size in mm.
  6. Input the appropriate thresholds. For our prostate data we use 3mm/5s as an example.
  7. Input the required pretreatment arc length in degrees.
  8. Depending on whether the images are inverted or not, tick or untick the inverted checkbox so that markers appear light on a dark background in the following screen.
  9. Click on Continue to run the software. The following screen (Figure 2) should pop up.
  10. The trajectory file "MarkerLocations_CouchShift_0.txt" will be output the the directory selected in Source.
KIM Action

Figure 2: KIM Gating software during acquisition.


Prostate Trajectories

In 2011, 30 prostate cancer patients underwent conventionally fractionated Intensity Modulated Radiotherapy at the Royal North Shore Hospital. kV images were acquired during treatment. The data were analysed post treatment to determine how much the prostate moved during treatment. No treatment intervention was performed during treatment.

The prostate trajectory data obtained have been published in the Red Journal here.

Figure 3 shows a variety of prostate trajectories observed in that clinical study.

Prostate Trajectories

Figure 3: Varieties of prostate trajectories observed during IMAT treatment with KIM.

Raw Images and Trajectory Data

Trajectory Trajectory Data Raw Images
Stable Trajectory Link Pat01Frac03
Continuous Drift Link Pat04Frac17
Transient Excursions Link Pat08Frac29
Persistent Excursions Link Pat08Frac36
High-frequency Excursions Link Pat09Frac36
Erratic Behaviour Link Pat09Frac32

If a login is required, please use:
login: radphyslab@outlook.com or radphyslab2@outlook.com
password: kimgating3/5

Contact

For technical inquiries regarding the software please contact
jin.aun@sydney.edu.au

To request further data, please send a 3TB powered external hard drive to the following address:

Radiation Physics Laboratory
Room 475, Blackburn Building - D06
Camperdown Campus
University of Sydney
2006 NSW
Sydney
AUSTRALIA