Molecular Virology Research Group

Research Highlights

EV71 Virulence

Basic research on EV71 molecular biology and pathogenesis is being undertaken within Dr Peter McMinn's group at University of Sydney, Australia. This research is aimed at understanding the molecular genetics of EV71 virulence. This includes studies of EV71 receptor interactions, EV71 replication and animal model studies of EV71 pathogenesis. The ultimate aim of this research is to develop a live attenuated vaccine against EV71.

Selected publications

  1. McWilliam Leitch, E., Bendig, J., Cabrerizo, M., Cardosa, J., Hyypiä, T., Ivanova, O., Kelly, A., Kroes, A., Lukashev, A., Macadam, A., McMinn, P., Roivainen, M., Trallero, G., Evans, D., Simmonds, P. Transmission networks and population turnover of echovirus 30. Journal of virology. 2009; 83:2109-18.
  2. Kok, C., McMinn, P. Picornavirus RNA-dependent RNA polymerase. The international journal of biochemistry & cell biology. 2009; 41:498-502.
    Chua, B., Phuektes, P., Sanders, S., Nicholls, P., McMinn, P. The molecular basis of mouse adaptation by human enterovirus 71. The Journal of general virology. 2008; 89:1622-1632.
  3. How, O., Cardosa, M., Thuong, T., Tien, N., Perera, D., Van Tu, P., Thao, N., McMinn, P., Huu, T. Epidemiologic and virologic investigation of hand, foot, and mouth disease, Southern Vietnam, 2005. Emerging Infectious Diseases. 2007; 13:1733-1741.