Obesity, Diabetes and Cardiovascular Disease

Sydney Medical School’s obesity, diabetes and cardiovascular disease research programs include basic biology, clinical medicine and policy research into the most effective ways of containing risk factors.

We have a number of world-renowned programs in the causes, prevention and treatment of heart and vascular disease, and in preventative public
health measures.

Research highlights

  • Professor David Celermajer’s research on early detection of cardiovascular disease has included the discovery of endothelial function testing by non-invasive ultrasound, enabling the detection of vascular disease in children and young adults.
  • A study led by Professor Chris Semsarian involving genetic testing revealed new insights into the causes of sudden death in young Australians and New Zealanders.
  • A major clinical trial involving University of Sydney researchers changed practice by showing that the drug fenofibrate reduced the risk of amputation and need for retinal laser treatment in people with diabetes.
  • A home-visiting program to new mothers in China, supported by Sydney Medical School, remains the only successful intervention internationally, in preventing obesity in early life.
  • In a world first, University of Sydney and University of Washington affiliate scientists have collaborated successfully to grow heart muscle cells in sufficient quantity to repair the damaged heart of a primate after myocardial infarction.

The Charles Perkins Centre

Charles Perkins Centre

The Charles Perkins Centre is based in a $385 million research and education facility at the University of Sydney dedicated to reducing the impact of obesity, diabetes and cardiovascular disease. The centre brings together research groups from the enabling sciences, biomedical sciences, bioinformatics, clinical research, clinical trials and health policy.

Boden Institute for Obesity, Nutrition, Exercise & Eating Disorders

Borden Institute

The Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders is a joint initiative of the Faculties of Health Sciences, Medicine and Science. It is committed to reducing the individual and societal impact of obesity, eating disorders and lifestyle-related chronic disease such as type 2 diabetes, heart disease, hypertension, cancer, mental illness and osteoarthritis.

Meet our researchers

Professor Louise Baur

Professor Louise Baur

Louise Baur is Professor in Paediatrics and Child Health at Sydney Medical School and is one of Australia’s leaders in the field of research on child and adolescent obesity.
Her research has looked at prevention of childhood obesity, the precursors of obesity, the complications of paediatric obesity and the effective management of obesity and related disorders.

Professor David Celermajer

Professor David Celermajer

Professor Celermajer’s groundbreaking research has demonstrated that the earliest stages of atherosclerotic heart disease can be detected in children 10 years and younger.

More recently, he and his team have developed new ultrasound and MRI scanning techniques to enable early detection of vascular disease in children and young adults, potentially leading to prevention of heart disease later in life.