Clinical Associate Professor Brian McCaughan

Clinical Associate Professor
Surgery, Central Clinical School

C39 - Royal Prince Alfred Hospital
The University of Sydney
NSW 2006 Australia

T: +61 2 9550 1933
F: +61 2 9550 6669
E:

Publications

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Linton, A., Cheng, Y., Griggs, K., Kirschner, M., Gattani, S., Srikaran, S., Chuan-Hao Kao, S., McCaughan, B., Klebe, S., van Zandwijk, N., Reid, G. (2014), An RNAi-based screen reveals PLK1, CDK1 and NDC80 as potential therapeutic targets in malignant pleural mesothelioma. British Journal of Cancer. 110(2), 510-519. [Abstract]

2013

   
  • Reid, G., Pel, M., Kirschner, M., Cheng, Y., Mugridge, N., Weiss, J., Williams, M., Wright, C., Edelman, J., Vallely, M., McCaughan, B., Klebe, S., Brahmbhatt, H., Macdiarmid, J., van Zandwijk, N. (2013), Restoring expression of miR-16: a novel approach to therapy for malignant pleural mesothelioma. Annals of Oncology. 24(12), 3128-3135. [Abstract]
  • Kao, S., Lee, K., Klebe, S., Henderson, D., McCaughan, B., Vardy, J., Clarke, S., van Zandwijk, N. (2013), Excision Repair Cross Complementation Group 1 and Thymidylate Synthase Expression in Patients With Mesothelioma. Clinical Lung Cancer. 14(2), 164-171. [Abstract]
  • Cheng, Y., Kirschner, M., Cheng, N., Gattani, S., Klebe, S., Edelman, J., Vallely, M., McCaughan, B., Jin, H., van Zandwijk, N., Reid, G. (2013), ZIC1 Is Silenced and Has Tumor Suppressor Function in Malignant Pleural Mesothelioma. Journal of Thoracic Oncology. 8(10), 1317-1328. [Abstract]
  • Tran, T., Selinger, C., Kohonen-Corish, M., McCaughan, B., Kennedy, C., O'Toole, S., Cooper, W. (2013), Fibroblast growth factor receptor 1 (FGFR1) copy number is an independent prognostic factor in non-small cell lung cancer. Lung Cancer. 81(3), 462-467. [Abstract]
  • Cooper, W., Yu, B., Yip, P., Ng, C., Lum, T., Farzin, M., Trent, R., Mercorella, B., Clarkson, A., Kohonen-Corish, M., Horvath, L., Kench, J., McCaughan, B., Gill, A., O'Toole, S. (2013), EGFR mutant-specific immunohistochemistry has high specificity and sensitivity for detecting targeted activating EGFR mutations in lung adenocarcinoma. Journal of Clinical Pathology. 66(9), 744-748. [Abstract]
  • Selinger, C., Rogers, T., Russell, P., O'Toole, S., Yip, P., Wright, G., Wainer, Z., Horvath, L., Boyer, M., McCaughan, B., Kohonen-Corish, M., Fox, S., Cooper, W., Solomon, B. (2013), Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization. Modern Pathology. 26(12), 1545-1553. [Abstract]
  • Yip, P., Yu, B., Cooper, W., Selinger, C., Ng, C., Kennedy, C., Kohonen-Corish, M., McCaughan, B., Trent, R., Boyer, M., Kench, J., Horvath, L., O'Toole, S. (2013), Patterns of DNA Mutations and ALK Rearrangement in Resected Node Negative Lung Adenocarcinoma. Journal of Thoracic Oncology. 8(4), 408-414. [Abstract]
  • Wright, C., Kirschner, M., Cheng, Y., O'Byrne, K., Gray, S., Schelch, K., Hoda, M., Klebe, S., McCaughan, B., van Zandwijk, N., Reid, G. (2013), Long Non Coding RNAs (lncRNAs) Are Dysregulated in Malignant Pleural Mesothelioma (MPM). PloS One. 8(8), e70940. [Abstract]

2012

   
  • Poursoltan, P., Currey, N., Pangon, L., van Kralingen, C., Selinger, C., Mahar, A., Cooper, W., Kennedy, C., McCaughan, B., Trent, R., Kohonen-Corish, M. (2012), Loss of heterozygosity of the Mutated in Colorectal Cancer gene is not associated with promoter methylation in non-small cell lung cancer. Lung Cancer. 77(2), 272-276. [Abstract]
  • Chua, T., Scolyer, R., Kennedy, C., Yan, T., McCaughan, B., Thompson, J. (2012), Surgical Management of Melanoma Lung Metastasis: An Analysis of Survival Outcomes in 292 Consecutive Patients. Annals of Surgical Oncology. 19(6), 1774-1781. [Abstract]
  • Kao, S., Armstrong, N., Condon, B., Griggs, K., McCaughan, B., Maltby, S., Wilson, A., Henderson, D., Klebe, S. (2012), Aquaporin 1 is an independent prognostic factor in pleural malignant mesothelioma. Cancer. 118(11), 2952-2961. [Abstract]
  • Kirschner, M., Cheng, Y., Badrian, B., Kao, S., Creaney, J., Edelman, J., Armstrong, N., Vallely, M., Musk, A., Robinson, B., McCaughan, B., Klebe, S., Mutsaers, S., van Zandwijk, N., Reid, G. (2012), Increased Circulating miR-625-3p: A Potential Biomarker for Patients With Malignant Pleural Mesothelioma. Journal of Thoracic Oncology. 7(7), 1184-1191. [Abstract]
  • Dear, R., Kelly, P., Wright, G., Stalley, P., McCaughan, B., Tattersall, M. (2012), Pulmonary metastasectomy for bone and soft tissue sarcoma in Australia: 114 patients from 1978 to 2008. Asia-Pacific Journal of Clinical Oncology. 8(3), 292-302. [Abstract]
  • Yip, P., Barnes, D., McCaughan, B., Boyer, M. (2012), Diagnosis and treatment of lung cancer: A focus on the GP's role. Medicine Today. 13(2), 30-36.

2011

   
  • Weder, W., Stahel, R., Baas, P., Dafni, U., de Perrot, M., McCaughan, B., Nakano, T., Pass, H., Robinson, B., Rusch, V., Sugarbaker, D., van Zandwijk, N. (2011), The MARS feasibility trial: conclusions not supported by data. Lancet Oncology. 12(12), 1093-1094. [Abstract]
  • Kao, S., Klebe, S., Henderson, D., Reid, G., Chatfield, M., Armstrong, N., Yan, T., Vardy, J., Clarke, S., van Zandwijk, N., McCaughan, B. (2011), Low Calretinin Expression and High Neutrophil-To-Lymphocyte Ratio Are Poor Prognostic Factors in Patients with Malignant Mesothelioma Undergoing Extrapleural Pneumonectomy. Journal of Thoracic Oncology. 6(11), 1923-1929. [Abstract]
  • Robinson, B., Kennedy, C., McLean, J., McCaughan, B. (2011), Node-Negative Non-small Cell Lung Cancer: Pathological Staging and Survival in 1765 Consecutive Cases. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer. 6(10), 1691-6. [Abstract]
  • Cao, C., Yan, T., Bannon, P., McCaughan, B. (2011), Summary of Prognostic Factors and Patient Selection for Extrapleural Pneumonectomy in the Treatment of Malignant Pleural Mesothelioma. Annals of surgical oncology. 18(10), 2973-9. [Abstract]
  • Haghshenasskashani, A., Rahnavardi, M., Yan, T., McCaughan, B. (2011), Intra-thoracic application of a vacuum-assisted closure device in managing pleural space infection after lung resection: is it an option?. Interactive Cardiovascular and Thoracic Surgery. 13(2), 168-174. [Abstract]
  • Poh, C., Yan, T., Vallely, M., Bannon, P., McCaughan, B. (2011), Pulmonary parenchymal endometriosis presenting as bilateral pneumothoraces. Journal of Obstetrics and Gynaecology. 31(5), 452-453. [Abstract]
  • Selinger, C., Cooper, W., Al-Sohaily, S., Mladenova, D., Pangon, L., Kennedy, C., McCaughan, B., Stirzaker, C., Kohonen-Corish, M. (2011), Loss of Special AT-Rich Binding Protein 1 Expression is a Marker of Poor Survival in Lung Cancer. Journal of Thoracic Oncology. 6(7), 1179-1189. [Abstract]
  • Kao, S., Griggs, K., Lee, K., Armstrong, N., Clarke, S., Vardy, J., van Zandwijk, N., Burn, J., McCaughan, B., Henderson, D., Klebe, S. (2011), Validation of a minimal panel of antibodies for the diagnosis of malignant pleural mesothelioma. Pathology. 43(4), 313-7. [Abstract]
  • Cao, C., Andvik, S., Yan, T., Kennedy, C., Bannon, P., McCaughan, B. (2011), Staging of patients after extrapleural pneumonectomy for malignant pleural mesothelioma - institutional review and current update. Interactive Cardiovascular and Thoracic Surgery. 12(5), 754-757. [Abstract]
  • Kao, S., Yan, T., Lee, K., Burn, J., Henderson, D., Klebe, S., Kennedy, C., Vardy, J., Clarke, S., van Zandwijk, N., McCaughan, B. (2011), Accuracy of Diagnostic Biopsy for the Histological Subtype of Malignant Pleural Mesothelioma. Journal of Thoracic Oncology. 6(3), 602-605. [Abstract]
  • Kao, S., Lee, K., Armstrong, N., Clarke, S., Vardy, J., van Zandwijk, N., Reid, G., Burn, J., McCaughan, B., Henderson, D., Klebe, S. (2011), Validation of tissue microarray technology in malignant pleural mesothelioma. Pathology. 43(2), 128-132. [Abstract]
  • Cao, C., Yan, T., Kennedy, C., Hendel, N., Bannon, P., McCaughan, B. (2011), Bronchopulmonary carcinoid tumors: long-term outcomes after resection. The Annals of Thoracic Surgery. 91(2), 339-343. [Abstract]
  • Yan, T., Cao, C., Boyer, M., Tin, M., Kennedy, C., McLean, J., Bannon, P., McCaughan, B. (2011), Improving survival results after surgical management of malignant pleural mesothelioma: an Australian institution experience. Annals of Thoracic and Cardiovascular Surgery. 17(3), 243-249. [Abstract]

2010

   
  • Cao, C., Yan, T., Bannon, P., McCaughan, B. (2010), A Systematic Review of Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma. Journal of Thoracic Oncology. 5(10), 1692-1703. [Abstract]
  • Lim, C., Stanford, D., Young, I., McCaughan, B., Cooper, W. (2010), Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia: a report of two cases. Pathology International. , 538-541. [Abstract]
  • Kao, S., McCaughan, B., Muljono, A., Boyer, M. (2010), A pathological complete response in malignant pleural mesothelioma after combination chemotherapy with Carboplatin and pemetrexed. Journal of Thoracic Oncology. 5(3), 405-406. [Abstract]

2009

   
  • Yan, T., Boyer, M., Tin, M., Wong, D., Kennedy, C., McLean, J., Bannon, P., McCaughan, B. (2009), Extrapleural pneumonectomy for malignant pleural mesothelioma: outcomes of treatment and prognostic factors. The Journal of Thoracic and Cardiovascular Surgery. 138(3), 619-624. [Abstract]
  • Cooper, W., Kohonen-Corish, M., McCaughan, B., Kennedy, C., Sutherland, R., Lee, C. (2009), Expression and prognostic significance of cyclin B1 and cyclin A in non-small cell lung cancer. Histopathology. 55(1), 28-36. [Abstract]
  • Kao, S., Mahon, K., Lin, B., Rutland, J., Pawsey, C., McCaughan, B., Beale, P. (2009), Pleural well-differentiated papillary mesothelioma: a case report. Journal of Thoracic Oncology. 4(7), 920-922. [Abstract]
  • Yan, T., Black, D., Bannon, P., McCaughan, B. (2009), Systematic review and meta-analysis of randomized and nonrandomized trials on safety and efficacy of video-assisted thoracic surgery lobectomy for early-stage non-small-cell lung cancer. Journal of Clinical Oncology. 27(15), 2553-2562. [Abstract]
  • Yan, T., Boyer, M., Tin, M., Sim, J., Kennedy, C., McLean, J., Bannon, P., McCaughan, B. (2009), Prognostic features of long-term survivors after surgical management of malignant pleural mesothelioma. The Annals of Thoracic Surgery. 87(5), 1552-1556. [Abstract]
  • Yan, T., Tin, M., Boyer, M., McLean, J., Bannon, P., McCaughan, B. (2009), Treatment Failure after Extrapleural Pneumonectomy for Malignant Pleural Mesothelioma. Journal of Thoracic Disease. 1(1), 23-28.

2008

   
  • Seng, T., Currey, N., Cooper, W., Lee, C., Chan, C., Horvath, L., Sutherland, R., Kennedy, C., McCaughan, B., Kohonen-Corish, M. (2008), DLEC1 and MLH1 promoter methylation are associated with poor prognosis in non-small cell lung carcinoma. British Journal of Cancer. 99(2), 375-382. [Abstract]
  • Cooper, W., Kohonen-Corish, M., Zhuang, L., McCaughan, B., Kennedy, C., Screaton, G., Sutherland, R., Lee, C. (2008), Role and prognostic significance of tumor necrosis factor-related apoptosis-inducing ligand death receptor DR5 in nonsmall-cell lung cancer and precursor lesions. Cancer. 113(1), 135-142. [Abstract]
  • Cooper, W., Kohonen-Corish, M., Chan, C., Kwun, S., McCaughan, B., Kennedy, C., Sutherland, R., Lee, C. (2008), Prognostic significance of DNA repair proteins MLH1, MSH2 and MGMT expression in non-small-cell lung cancer and precursor lesions. Histopathology. 52(5), 613-622. [Abstract]
  • O'Connell, T., Ben-Tovim, D., McCaughan, B., Szwarcbord, M., McGrath, K. (2008), Health services under siege: the case for clinical process redesign. The Medical Journal of Australia. 188(6 Suppl), S9-13. [Abstract]
  • MacLellan, D., Cregan, P., McCaughan, B., O'Connell, T., McGrath, K. (2008), Applying clinical process redesign methods to planned arrivals in New South Wales hospitals. The Medical Journal of Australia. 188(6 Suppl), S23-6. [Abstract]
  • Kenny, P., King, M., Viney, R., Boyer, M., Pollicino, C., McLean, J., Fulham, M., McCaughan, B. (2008), Quality of life and survival in the 2 years after surgery for non small-cell lung cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 26(2), 233-241. [Abstract]