Dr Nicholas Little

Clinical Senior Lecturer
Surgery, Northern Clinical School

E25 - Royal North Shore Hospital
The University of Sydney
NSW 2006 Australia

T: 02 9966 0057
F: 02 9966 0252
E:

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Themes | Keywords | Publications

 

Keywords

Microsurgery; Neuroendocrinology; Nervous system; Cancer; Neurosurgery

Publications

2011 | 2010 | 2009 | 2008 | 2007

2011

   
  • Fowler, A., Thomson, D., Giles, K., Maleki, S., Mreich, E., Wheeler, H., Leedman, P., Biggs, M., Cook, R., Little, N., Robinson, B., McDonald, K. (2011), miR-124a is frequently down-regulated in glioblastoma and is involved in migration and invasion. European journal of cancer (Oxford, England : 1990). 47(6), 953-63. [Abstract]
  • Parkinson, J., Afaghi, V., Payne, C., Buckland, M., Brewer, J., Biggs, M., Little, N., Wheeler, H., Cook, R., McDonald, K. (2011), The impact of molecular and clinical factors on patient outcome in oligodendroglioma from 20 years' experience at a single centre. Journal of Clinical Neuroscience. 18(3), 329-333. [Abstract]
  • Gonzalvo, A., Fowler, A., Cook, R., Little, N., Wheeler, H., McDonald, K., Biggs, M. (2011), Schwannomatosis, sporadic schwannomatosis, and familial schwannomatosis: a surgical series with long-term follow-up. Clinical article. Journal of Neurosurgery. 114(3), 756-762. [Abstract]
  • Little, N. (2011), A case of cauda equina syndrome. Medicine Today. 12(2), 74-75.

2010

   
  • Matar, E., Cook, R., Fowler, A., Biggs, M., Little, N., Wheeler, H., Robinson, B., McDonald, K. (2010), Post-contrast enhancement as a clinical indicator of prognosis in patients with anaplastic astrocytoma. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 17(8), 993-6. [Abstract]
  • McDonald, K., McDonnell, J., Muntoni, A., Henson, J., Hegi, M., von Deimling, A., Wheeler, H., Cook, R., Biggs, M., Little, N., Robinson, B., Reddel, R., Royds, J. (2010), Presence of Alternative Lengthening of Telomeres Mechanism in Patients With Glioblastoma Identifies a Less Aggressive Tumor Type With Longer Survival. Journal of neuropathology and experimental neurology. 69(7), 729-36. [Abstract]

2009

   
  • McCormack, A., McDonald, K., Gill, A., Clark, S., Burt, M., Campbell, K., Braund, W., Little, N., Cook, R., Grossman, A., Robinson, B., Clifton-Bligh, R. (2009), Low O(6)-methylguanine-DNA methyltransferase (MGMT) expression and response to temozolomide in aggressive pituitary tumours. Clinical endocrinology. 71(2), 226-33. [Abstract]
  • Elston, M., Gill, A., Conaglen, J., Clarkson, A., Cook, R., Little, N., Robinson, B., Clifton-Bligh, R., McDonald, K. (2009), Nuclear accumulation of e-cadherin correlates with loss of cytoplasmic membrane staining and invasion in pituitary adenomas. Journal of Clinical Endocrinology and Metabolism. 94(4), 1436-1442. [Abstract]

2008

   
  • Tacon, L., Parkinson, J., Hudson, B., Brewer, J., Little, N., Clifton-Bligh, R. (2008), Headache of a diagnosis: frontotemporal pain and inflammation associated with osteolysis. The Medical Journal of Australia. 189(10), 591-592. [Abstract]
  • Payne, C., Maleki, S., Messina, M., O'Sullivan, M., Stone, G., Hall, N., Parkinson, J., Wheeler, H., Cook, R., Biggs, M., Little, N., Teo, C., Robinson, B., McDonald, K. (2008), Loss of prostaglandin D2 synthase: a key molecular event in the transition of a low-grade astrocytoma to an anaplastic astrocytoma. Molecular Cancer Therapeutics. 7(10), 3420-3428. [Abstract]
  • Fowler, A., Cook, R., Biggs, M., Little, N., Assaad, N., McDonald, K. (2008), Survival of patients following neurosurgical treatment of colorectal adenocarcinoma metastasis in the Northern Sydney-Central Coast area. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 15(9), 998-1004. [Abstract]
  • Elston, M., Gill, A., Conaglen, J., Clarkson, A., Shaw, J., Law, A., Cook, R., Little, N., Clifton-Bligh, R., Robinson, B., McDonald, K. (2008), Wnt pathway inhibitors are strongly down-regulated in pituitary tumors. Endocrinology. 149(3), 1235-42. [Abstract]
  • Parkinson, J., Wheeler, H., Clarkson, A., McKenzie, C., Biggs, M., Little, N., Cook, R., Messina, M., Robinson, B., McDonald, K. (2008), Variation of O(6)-methylguanine-DNA methyltransferase (MGMT) promoter methylation in serial samples in glioblastoma. Journal of neuro-oncology. 87(0), 71-8. [Abstract]

2007

   
  • Morgan, M., Rochford, A., Tsahtsarlis, A., Little, N., Faulder, K. (2007), Surgical risks associated with the management of Grade I and II brain arteriovenous malformations. Neurosurgery. 61(1 Suppl), 417-22; discussion 422-4. [Abstract]
  • McDonald, K., O'Sullivan, M., Parkinson, J., Shaw, J., Payne, C., Brewer, J., Young, L., Reader, D., Wheeler, H., Cook, R., Biggs, M., Little, N., Teo, C., Stone, G., Robinson, B. (2007), IQGAP1 and IGFBP2: valuable biomarkers for determining prognosis in glioma patients. Journal of Neuropathology and Experimental Neurology. 66(5), 405-417. [Abstract]