Bio-Nanoscience & Nanotechnology in Medicine


The Sydney Nano Foundational Program in Bio-Nanoscience and Nanotechnology in Medicine aims to generate new knowledge in nanoscale phenomena in biomolecular and living systems, and also to develop and translate emerging nanotechnologies that can lead to medical breakthroughs.

Our research areas include: nanoparticles for disease detection, diagnostic imaging and targeted therapies; bio-nanomaterials for regenerative medicine; nanotechnology-enabled medical devices; bio-nano-sensors; bio-molecular nanotechnology; advanced bio-nanospectroscopy and imaging techniques.

Our research is highly interdisciplinary and involves collaboration with pre-clinical and clinical researchers at our affiliated medical research institutes and hospitals, as well as with industry partners in the biotech and health sectors.

Current Research Areas and Projects
Synthetic nanoparticles and nanosystems for disease detection, enhanced imaging and targeted therapy
Hyperpolarised nanodiamond for magnetic resonance imaging David Reilly
Magnetic nanosystems for image-guided targeted therapy Lou Rendina, Zdenka Kuncic
Particle Technology Daniela Traini
Nanosystems for the treatment of disease Richard Payne, Markus Muellner, Warwick Britton, Scott Byrne, Mat Todd
Fragment-based drug discovery Joel Mackay, Ann Kwan
Cylindrical polymer brushes in nanomedicine Markus Muellner, Liz New

Endogenous particles in inflammation and disease

Immune-modifying particle-induced tregs induce reemission in experimental autoimmune encephalomyelitis Nicholas King
Membrane particles in neuro-immuno pathology Georges Grau
Targeting monocytes with nanoparticles to prevent kidney allograft rejection Steven Chadban, Nicholas King, Huiling Wu, Daniel Getts
Antigen presentation in cerebral malaria pathogenesis: a role for brain micro vascular     endothelium and microparticles Georges Grau
Self assembled synthetic nanostructures
Nanotubes prepared through self-assembly of cyclic peptide/polymer conjugates into functional devices for applications as nano-pores Kate Joliffe 
DNA Origami Shelley Wickham
Bio-inspired liposome-based smart sensors Rona Chandrawati
Neuromorphic nanowire switch network Zdenka Kuncic
Bio-nano probes and medical device nanotechnologies
Lab-on-Chip for biosensing Stefano Palomba
Multi-modal nano-bio-spectroscopy Peter Lay
Nano-enhanced light extraction for medical imaging Shaghik Atakaramians, Zdenka Kuncic
Structural Biology 
Molecular mechanisms underlying gene regulation Joel Mackay, Jacqui Mathews, Sandro Ataide
Functional and pathological amyloid Margaret Sunde, Ann Kwan