News

ARC Outcome



8 November 2011

It gives me great pleasure to inform you that Professor Mike Swain, Dr Luiz Bertassoni, and A/Professor Chris Little were successful in the recently announced Australian Research Council Discovery Projects for their project: Nano-mechanical and nano-structural investigation of dentine: unravelling a novel nano-scale regulator of high durability of mineralised tissues.

This $370, 000 project proposes that proteoglycans (PG) are key regulators of the high durability of dentine. PGs are primarily responsible for the structural organization of collagen in all vertebrates, however virtually nothing is known about their role on the biomechanics of mineralized tissues. This study aims to thoroughly address this question.

Dr Bertassoni says "In this project we proposed a novel mechanism explaining the outstanding longevity of teeth. Our theories suggest that a nanoscale structure comprising less than 5% of the dentine matrix represents one of Nature's greatest secrets for this outstanding durability. We anticipate that by understanding these unknown mechanisms we may unravel novel pathological conditions, indicate etiological markers and therapeutic targets, as well as provide improved understanding of the effects of aging and dental disease progression that have not been discovered thus far."

I know you will all join me in congratulating them in their success.

Prof Chris Peck

Prof Mike Swain
Prof Mike Swain

Dr Luiz Bertassoni
Dr Luiz Bertassoni