Research domains define major disciplinary areas and provide the organisational framework to identify, nurture and grow capabilities within and across faculties and partner organisations to support the centre’s mission, objectives and outcomes.

Our research strategy focuses on four key domains and include:


This domain is the realm of epidemiology, population survey and genetic analysis, and cohort studies. Some project nodes in this domain will involve analysis of existing data sets (from which there is much still to be learned with imaginative data mining and hypothesis establishment of cohort studies, surveys and clinical trials.

Domain leader: to be appointed


Understanding the fundamental mechanisms of disease is essential for defining what might be possible by way of prevention, intervention and treatment. Work in this domain spans fundamental genetic and epigenetic mechanisms, systems metabolism, organ and whole organismal physiology, and behaviour. There will be use of model animal systems (including some that are non-traditional in biomedical research) and an appreciation of evolutionary and ecological principles.

Domain leader: Professor David E. James

Society and environment

Armed with an understanding of what interventions might work, based on an understanding of the biology of disease, this knowledge needs next to be placed within the context of human psychology, historical precedents, social and cultural norms and imperatives, ethical frameworks, the economic, legislative and political environments. They will also need to be considered in the wider contexts of the food production chain and the built environment. These topics are the purview of this domain.

Domain leader: Professor Paul Griffiths (acting)


All outputs from the other domains flow towards the solutions domain and the development of medical, educational and lifestyle interventions. The task is to work out how best to implement change, both at the individual (micro-) and macro- (e.g. policy) scales, and to assess the effectiveness of such measures. This program will require input and leadership from clinicians and other health practitioners, the arts and social sciences, psychologists, public health and policy experts and will engage industry, the community, governments and nongovernmental organisations and the media.

Domain leader: Professor Andrew Wilson