Professor David Hibbs

BSc (Hons) Chemistry, PhD
Professor of Bio-Pharmaceutical and Structural Chemistry

A15 - Pharmacy And Bank Building
The University of Sydney

Telephone +61 2 9351 6005
Fax +61 2 9351 4391

Biographical details

Bsc. (Hons) Chemistry, University of Wales Cardiff, 1989-1992.

PhD Chemistry, Cardiff University, 1998.

Postdoctoral Fellow, Cardiff University, 1998.

Royal Society Fellow, University of Sydney, 1999.

NH&MRC Research Scientist, University of Sydney, 2000.

ARC Postdoctoral Fellow, University of Sydney, 2001.

University of Sydney Fellow, 2004.

ARC Research Fellow, University of Sydney, 2005.

Research interests

  • Molecular Modelling and Computational Chemistry
  • Biological and Medicinal Chemistry
  • Drug Design
  • Solid state chemistry
  • High resolution X-ray and neutron diffraction
  • Experimental charge density distributions. ab initio and DFT calculations

Keywords

Biological and Medicinal Chemistry; Cardiovascular diseases; Cancer

Selected grants

2014

  • Co-crystals by Design; Hibbs D; DVC Research/Bridging Support Grant.
  • CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Huang M, Scolyer R, Fraser S, Sahni S, Speranza T, Owens T, Barrs V, Ju Y, Kovacevic Z, Lu Z, Camp A, Slobedman B, Morris B, Oliver B, dos Remedios C, Kalinowski D, Fu D, Lai D, Lovicu F, Allbutt H, Triccas J, Burgess J, Kril J, Dixon K, Rendina L, Byrne M, King N, Groundwater P, Williamson P, Ho P, Dong Q, Bao S, Assinder S, McLennan S, Richardson D, Ammit A, Sharland A, Hardikar A, Hong A, Hambly B, Lee C, Murphy C, Goldsbury C, Johnstone D, Lane D, Hibbs D, Joshua D, Huq F, Halliday G, Sutherland G, Zreiqat H, Lok H, Lyons J, Jansson J, Black J, Zhu L, Sunde M, Day M, Naylor M, Buckland M, Murray M, Shafie N, Lay P, Poronnik P, Codd R, Mason R, Ryan R, Christopherson R, de Graaf S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Richardson D, Kril J, Murphy C, Vandenberg R, Rendina L, dos Remedios C, Ju Y, Kovacevic Z, Lyons J, Sutherland G, Lay P, Ammit A, Lai D, Morris B, Day M, Dong Q, Bao S, Huang M, Camp A, Boyer M, Whittington R, Byrne M, Hanrahan J, Fu D, Jansson J, Lane D, Bagley E, Hibbs D, Zhang D, Fraser S, Scolyer R, Black J, Halliday G, Christie M, Zreiqat H, Murray M, Slobedman B, Naylor M, Burgess J, Triccas J, Mason R, Chadban S, Combes V, Lovicu F, McLennan S, Kalinowski D, Sharland A, Johnstone D, Groundwater P, Dixon K, Zhou F, Lovejoy D, Lu Z, Zhu L, Goldsbury C, Witting P, Buckland M, Assinder S, Purdie (Williams) A, Codd R, Owens T, Hambly B; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Novel Fluorogenic Probes for the Selective Detection of Pathogenic Bacteria; Groundwater P, Hibbs D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Thermogravimetric Analyser (TGA); Kepert C, D'Alessandro D, Perrier S, Hawkett B, Hibbs D, Wheate N, Harris A, Minett A, Ling C, Kennedy B; DVC Research/Equipment Grant.
  • HPLC-MS for high throughput drug and protein analysis; Payne R, Kassiou M, Cordwell S, Hibbs D, Groundwater P, Shepherd N; DVC Research/Equipment Grant.

2012

  • GeneAtlas Personal Microarray System; Richardson D, Scolyer R, Stocker R, Weninger W, Black J, Allen D, Murray M, Mason R, Twigg S, King N, Horvath L, Lovicu F, Lee C, Halliday G, Lovejoy D, Joshua D, Sharland A, Roufogalis B, Hambly B, Morris B, Bao S, Bishop G, Hibbs D, Lane D, Zhou F, Hanrahan J, Dixon K, Rendina L, Byrne M, Naylor M, Cole N, Jansson J, Dong Q, Codd R, Payne R, Assinder S, Chadban S, Fraser S, McLennan S, Suryo Rahmanto A, Lai D, Yu Y, Ju Y, Buckland M, Kovacevic Z, Saletta F, Zreiqat H, Kalinowski D, Groundwater P, Simes R, Zhang D, Boyer M, Murphy C; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2010

  • MKP-1 as a novel anti-inflammatory strategy in asthma and airway remodelling.; Hibbs D, Ammit A; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

2009

  • MKP-1 as a novel anti-inflammatory strategy in asthma and airway remodelling; Ammit A, Hibbs D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Bruker APEX II CCD Detector Fourth Generation APEX II ultra-low noise CCD X-ray detector with 16 megapixel chip; Hibbs D, Roufogalis B, Murray M, Hambley T, Hanrahan J, Church W, Collins (Chebib) M, Johnston G, Young P, Traini D; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Bruker APEXII X-ray diffractometer detector; Hibbs D, Roufogalis B; Clive & Vera Ramaciotti Foundation/Awards for Biomedical Research: Major Equipment.

2007

  • Precision Titration/ Solution Calorimeter accessory for the Tam III Iosthermal calorimeter Calorimet; Chan H, Murray M, Hibbs D, Young P, Traini D, Weiss A, Stewart P; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • State of the art high resolution thermal analysis suite for the life and material sciences; Stewart P, Young P, Traini D, Chan H, Murray M, Dehghani F, Hibbs D, Larson I, Warr G, Weiss A; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2006

  • Molecular Simulation of the Effects of Additives on Generation of Dry Powder Aerosols; Hibbs D, Chan H; University of Sydney/Research & Development.

2005

  • Experimental electron densities, crystal engineering and molecular recognition: a supramolecular approach to drug design; Hibbs D; Australian Research Council (ARC)/Discovery Projects (DP).

2003

  • Ultra-Sensitive CCD Diffractometer with High Intensity X-ray Photon Generator; Hambley T, Kepert C, Turner P, Spackman M, Williams P, Pyne S, Try A, Hibbs D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2002

  • Experimental Charge Density Studies of Hydrogen Bonding; Hibbs D; Australian Research Council (ARC)/Discovery Projects (DP).

2001

  • Australian Synchrotron Research Program - Travel Grant - access to international facilities.; Hibbs D; Australian Nuclear Science and Technology Organisation/Australian Synchrotron Research Program.
  • Experimental charge density studies and drug design; Australian Research Council (ARC)/Australian Postdoctoral Fellowship.

Selected publications

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Book Chapters

  • Shankar, G., Charleston, M., Murray, M., Hibbs, D. (2007). A structural and phylogenetic analysis of cytochrome P450. In Damjana Rozman (Eds.), Proceedings of the 15th International Conference on Cytochromes P450: Biochemistry, Biophysics and Functional Genomics, (pp. 75-80). Bologna, Italy: Medimond.
  • Pavel, D., Hibbs, D., Shanks, R. (2007). Review of main chain liquid crystalline polymers. In Firas Awaja (Eds.), Advanced Research in Polymer Science, (pp. 65-84). Kerala, India: Transworld Research Network.

Journals

  • Raguine, L., Ali, M., Bender, V., Diefenbach, E., Doddareddy, M., Hibbs, D., Manolios, N. (2013). Alanine Scan of an Immunosuppressive Peptide (CP): Analysis of Structure-Function Relationships. Chemical Biology & Drug Design, 81(2), 167-174. [More Information]
  • Ng, N., Leverett, P., Hibbs, D., Yang, Q., Bulanadi, J., Wu, M., Aldrich-Wright, J. (2013). The antimicrobial properties of some copper(ii) and platinum(ii) 1,10-phenanthroline complexes. Dalton Transactions, 42(9), 3196-3209. [More Information]
  • Matin, A., Doddareddy, M., Gavande, N., Nammi, S., Groundwater, P., Roubin, R., Hibbs, D. (2013). The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists. Bioorganic and Medicinal Chemistry, 21(3), 766-778. [More Information]
  • Banister, S., Wilkinson, S., Longworth, M., Stuart, J., Apetz, N., English, K., Brooker, L., Goebel, C., Hibbs, D., Glass, M., McGregor, I., Kassiou, M., et al (2013). The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse. ACS Chemical Neuroscience, 4(7), 1081-1092. [More Information]
  • Banister, S., Wilkinson, S., Hanani, R., Reynolds, A., Hibbs, D., Kassiou, M. (2012). A practical, multigram synthesis of the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpy-razolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of high affinity translocator protein (TSPO) ligands. Tetrahedron Letters, 53(29), 3780-3783. [More Information]
  • Banister, S., Manoli, M., Doddareddy, M., Hibbs, D., Kassiou, M. (2012). A σ1 receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDS). Bioorganic & Medicinal Chemistry Letters, 22(19), 6053-6058. [More Information]
  • Cui, P., Rawling, T., Bourget, K., Kim, T., Duke, C., Doddareddy, M., Hibbs, D., Zhou, F., Tattam, B., Petrovic, N., Murray, M. (2012). Antiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2. Journal of Medicinal Chemistry, 55(16), 7163-7172. [More Information]
  • Beinat, C., Banister, S., Prehn, S., Doddareddy, M., Hibbs, D., Sako, M., Collins (Chebib), M., Tran, T., Al-Muhtasib, N., Xiao, Y., Kassiou, M. (2012). Consequences of linker length alteration of the alpha7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333. Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, 22(7), 2380-2384. [More Information]
  • Manetsch, M., Ramsay, E., King, E., Seidel, P., Che, A., Ge, Q., Hibbs, D., Newton, R., Ammit, A. (2012). Corticosteroids and B2-agonists upregulate mitogen-activated protein kinase phosphatase 1: in vitro mechanisms. British Journal of Pharmacology, 166(7), 2049-2059. [More Information]
  • Petch, D., Anderson, R., Cunningham, A., George, S., Hibbs, D., Liu, R., Mackay, S., Paul, A., Small, D., Groundwater, P. (2012). Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis. Bioorganic & Medicinal Chemistry Letters, 20(19), 5901-5914. [More Information]
  • Zhao, Y., Hibbs, D., Groundwater, P., Wassef, A. (2012). Diethyl 4-(4-acetamidophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Acta Crystallographica. Section E: Structure Reports Online, 68(8), 1-8. [More Information]
  • Failes, T., Mitic, G., Abdel-Halim, H., Po'uha, S., Liu, M., Hibbs, D., Kavallaris, M. (2012). Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells. PLoS One, 7(2), 1-11. [More Information]
  • Nguyen, T., Howard, S., Hanrahan, J., Groundwater, P., Platts, J., Hibbs, D. (2012). Experimental and Theoretical Charge Density Distribution in a Host-Guest System: Synthetic Terephthaloyl Receptor Complexed to Adipic Acid. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 116, 5618-5628. [More Information]
  • Nguyen, T., Groundwater, P., Platts, J., Hibbs, D. (2012). Experimental and theoretical charge density studies of 8-hydroxyquinoline cocrystallized with salicylic acid. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 116(13), 3420-3427. [More Information]
  • Ghassabian, S., Rawling, T., Zhou, F., Doddareddy, M., Tattam, B., Hibbs, D., Edwards, R., Cui, P., Murray, M. (2012). Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochemical Pharmacology, 84(2), 215-223. [More Information]
  • Zhao, Y., Groundwater, P., Hibbs, D., Nguyen, P., Narlawar, R. (2011). (1E,4Z,6E)-5-Hydroxy-1,7-bis(2-meth-oxyphenyl)-1,4,6-heptatrien-3-one. Acta Crystallographica. Section E: Structure Reports Online, E67(8), o1885. [More Information]
  • Orlandi, P., Demartin, F., Pasero, M., Leverett, P., Williams, P., Hibbs, D. (2011). Gelosaite, BiMo6+ (2-5x)Mo5+ 6xO7(OH)·H2O (0 ≤ x ≤ 0.4), a new mineral from Su Senargiu (CA), Sardinia, Italy, and a second occurrence from Kingsgate, New England, Australia. American Mineralogist, 96, 268-273. [More Information]
  • Abdel-Halim, H., Traini, D., Hibbs, D., Gaisford, S., Young, P. (2011). Modelling of molecular phase transitions in pharmaceutical inhalation compounds: an in silico approach. European Journal of Pharmaceutics and Biopharmaceutics, 78(1), 83-89. [More Information]
  • Lo, A., Salam, N., Hibbs, D., Rutledge, P., Todd, M. (2011). Polyamide-Scorpion Cyclam Lexitropsins Selectively Bind AT-Rich DNA Independently of the Nature of the Coordinated Metal. PLoS One, 6(5), e17446-1-e17446-13. [More Information]
  • Sciberras, M., Leverett, P., Williams, P., Hibbs, D., Roberts, A., Grice, J. (2011). The Single-Crystal X-Ray Structure of Gagarinite-(Ce). Canadian Mineralogist: crystallography, geochemistry, mineralogy, petrology, mineral deposits, 49, 1111-1114. [More Information]
  • Ning, F., Anderson, R., Hibbs, D., Groundwater, P. (2010). A new, one-step synthesis of 1-heteroaryl-2-alkylaminoethanols. Tetrahedron Letters, 51, 843-845.
  • Nebot, N., Crettol, S., D'Esposito, F., Tattam, B., Hibbs, D., Murray, M. (2010). Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes. British Journal of Pharmacology, 161(5), 1059-1069. [More Information]
  • Reynolds, A., Hanani, R., Hibbs, D., Damont, A., Da Pozzo, E., Selleri, S., Dolle, F., Martini, C., Kassiou, M. (2010). Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO). Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, 20(19), 5799-5802. [More Information]
  • Matin, A., Gavande, N., Kim, M., Yang, N., Salam, N., Hanrahan, J., Roubin, R., Hibbs, D. (2009). 7-Hydroxy-benzopyran-4-one Derivatives: A Novel Pharmacophore of Peroxisome Proliferator-Activated Receptor and - (PPAR and ) Dual Agonists. Journal of Medicinal Chemistry, 52(21), 6835-6850. [More Information]
  • Mewett, K., Fernandez, S., Pasricha, A., Pong, A., Devenish, S., Hibbs, D., Collins (Chebib), M., Johnston, G., Hanrahan, J. (2009). Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors. Bioorganic and Medicinal Chemistry. [More Information]
  • Hall, M., Salam, N., Hellawell, J., Fales, H., Kensler, C., Ludwig, J., Szakacs, G., Hibbs, D., Gottesman, M. (2009). Synthesis, Activity, and Pharmacophore Development for Isatin-Beta-thiosemicarbazones with Selective Activity toward Multidrug-Resistant Cells. Journal of Medicinal Chemistry, 52(10), 3191-3204. [More Information]
  • Abdel-Halim, H., Hanrahan, J., Hibbs, D., Johnston, G., Collins (Chebib), M. (2008). A molecular basis for agonist and antagonist actions at GABA(C) receptors. Chemical Biology and Drug Design (Print), 71(4), 306-327. [More Information]
  • Liaw, T., Salam, N., McKay, M., Cunningham, A., Hibbs, D., Kavallaris, M. (2008). Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions. Molecular Cancer Therapeutics, 7(10), 3150-3159. [More Information]
  • Kumar, R., Collins (Chebib), M., Hibbs, D., Kim, H., Johnston, G., Salam, N., Hanrahan, J. (2008). Novel gamma-aminobutyric acid rho(1) receptor antagonists; Synthesis, pharmacological activity and structure-activity relationships. Journal of Medicinal Chemistry, 51(13), 3825-3840. [More Information]
  • Salam, N., Huang, H., Kota, B., Kim, M., Li, Y., Hibbs, D. (2008). Novel PPAR-gamma agonists identified from a natural product library: A virtual screening, induced-fit docking and biological assay study. Chemical Biology and Drug Design (Print), 71(1), 57-70. [More Information]
  • Overgaard, J., Waller, M., Piltz, R., Platts, J., Emseis, P., Leverett, P., Williams, P., Hibbs, D. (2007). Experimental and Theoretical Charge Density Distribution in Two Ternary Cobalt(III) Complexes of Aromatic Amino Acids. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 111(40), 10123-10133. [More Information]
  • Overgaard, J., Turel, I., Hibbs, D. (2007). Experimental electron density study of a complex between copper(ii) and the antibacterial quinolone family member ciprofloxacin. Dalton Transactions: an international journal of inorganic, organometallic and bioinorganic chemistry, 2007 (21), 2171-2178. [More Information]
  • Battle, A., Edwards, P., Haigh, R., Hibbs, D., Li, D., Liddiard, S., Newman, P. (2007). Synthesis and Characterization of Iron(II) Complexes of 10- and 11-Membered Triphosphamacrocycles. Organometallics, 26(2), 377-386.
  • CLISSOLD, M., Leverett, P., Williams, P., Hibbs, D., NICKEL, E. (2007). The structure of gillardite, the Ni-analogue of herbertsmithite, from Widgiemooltha, Western Australia. Canadian Mineralogist: crystallography, geochemistry, mineralogy, petrology, mineral deposits, 45(2), 317-320.
  • Starke-Peterkovic, T., Turner, N., Vitha, M., Waller, M., Hibbs, D., Clarke, R. (2006). Cholesterol effect on the dipole potential of lipid membranes. Biophysical Journal, 90(11), 4060-4070. [More Information]
  • Waller, M., Robertazzi, A., Platts, J., Hibbs, D., Williams, P. (2006). Hybrid density functional theory for pi-stacking interactions: application to benzenes, pyridines, and DNA bases. Journal of Computational Chemistry, 27(4), 491-504. [More Information]
  • Waller, M., Howard, S., Platts, J., Piltz, R., Willock, D., Hibbs, D. (2006). Novel properties from experimental charge densities: an application to the Zwitterionic neurotransmitter taurine. Chemistry: A European Journal, 12(29), 7603-7614. [More Information]
  • Battle, A., Choi, R., Hibbs, D., Hambley, T. (2006). Platinum(IV) analogues of AMD473 (cis-[PtCl2(NH3)(2-picoline)]): preparative, structural, and electrochemical studies. Inorganic Chemistry, 45(16), 6317-6322. [More Information]
  • Howard, S., Hibbs, D., Amoroso, A., Platts, J. (2006). Quantum-Chemical Design of Cryptand-like Ditopic Salt Binders. Journal of Chemical Theory and Computation, 2(2), 354-363.
  • Ali, M., Salam, N., Amon, M., Bender, V., Hibbs, D., Manolios, N. (2006). T-cell antigen receptor-alpha chain transmembrane peptides: correlation between structure and function. International Journal of Peptide Research and Therapeutics, 12(3), 261-267.
  • Hibbs, D., Howard, S., Huke, J., Waller, M. (2005). A new orbital-based model for the analysis of experimental molecular charge densities: an application to (Z)-N-methyl-C-phenylnitrone. Physical Chemistry Chemical Physics, 7(8), 1772. [More Information]
  • Bell, N., Bradley, C., Broughton, R., Coles, S., Hibbs, D., Hursthouse, M., Ray, A., Simmonds, D., Thorpe, S. (2005). Comparison of the structure property relationships in LB films of zwitterionic TCNQ adducts. Journal of Materials Chemistry, 15(14), 1437-1445.
  • Nguyen, T., Hibbs, D., Howard, S. (2005). Conformations, Energies, and Intramolecular Hydrogen Bonds in Dicarboxylic Acids: Implications for the Design of Synthetic Dicarboxylic Acid Receptors. Journal of Computational Chemistry, 26(12), 1233-1241. [More Information]
  • Hibbs, D., Overgaard, J., Howard, S., Nguyen, T. (2005). Experimental charge density of a potential DHO synthetase inhibitor: dimethyl-trans-2-oxohexahydro-pyrimidine-4,6-dicarboxylate. Organic and Biomolecular Chemistry, 3(3), 441-447. [More Information]
  • Nyerges, M., Bendell, D., Arany, A., Hibbs, D., Coles, S., Hursthouse, M., Groundwater, P., Meth-Cohn, O. (2005). Silver acetate-catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides. Tetrahedron, 61(15), 3745-3753.
  • Hibbs, D., Overgaard, J., Platts, J., Waller, M., Hursthouse, M. (2004). Experimental And Theoretical Charge Density Studies Of Tetrafluorophthalonitrile And Tetrafluoroisophthalonitrile. The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, 108(11), 3663-3672.
  • Emseis, P., Failes, T., Hibbs, D., Leverett, P., Williams, P. (2004). Intramolecular Nh-Pi And Pi-Pi Interactions In Ternary Cobalt(III) Complexes Of Aromatic Aminoacids: A Structural And NMR Study. Polyhedron, 23(10), 1749-1767.
  • Allan, R., Greenwood, J., Hambley, T., Hanrahan, J., Hibbs, D., Itani, S., Tran, H., Turner, P. (2004). Studies On Pyridazine Azide Cyclisation Reactions. Organic and Biomolecular Chemistry, 2(12), 1782-8-1788.
  • Duke, R., Collins (Chebib), M., Hibbs, D., Mewett, K., Johnston, G. (2004). Synthesis And Resolution Of 2-Methyl Analogues Of GABA. Tetrahedron-Asymmetry, 15(11), 1745-1751.
  • Overgaard, J., Hibbs, D. (2004). The Experimental Electron Density In Polymorphs A And B Of The Anti-Ulcer Drug Famotidine. Acta Crystallographica Section A: Foundations of Crystallography, 60, 480-487.
  • Emseis, P., Hibbs, D., Leverett, P., Reddy, N., Williams, P. (2004). The structure of Λ-β1-[Co(R,R-picchxn)(S-tyr)]Br2 · 3.5H2O and solution configuration of Λ-β1-[Co(R,R-picchxn)(aromatic S-aminoacidate)]2+ complexes: model systems for the investigation of non-covalent aromatic interactions. Inorganica Chimica Acta, 357(11), 3251-3263. [More Information]
  • Emseis, P., Hibbs, D., Leverett, P., Reddy, N., Williams, P. (2004). Weak Intramolecular Interactions In Perchlorate Salts Of Lambda-Beta(1)- Co(R,R-Picchxn)(R-Aa) (2+) Picchxn = N,N '-Di(2-Picolyl)-1,2-Diaminocyclohexane; Aa = Phenylalaninato(1-), Tyrosinato(1-) And Their Diastereoisomeric Equilibration In Solution. Inorganica Chimica Acta, 357(9), 2669-2676. [More Information]
  • Coogan, M., Haigh, R., Hall, A., Harris, L., Hibbs, D., Jenkins, R., Jones, C., Tomkinson, N. (2003). A new chiral diol derived from tetralone for the complexation of Lewis acids. Tetrahedron, 59(37), 7389-7395.
  • Hibbs, D., Leverett, P., Williams, P. (2003). A single crystal X-ray study of a sulphate-bearing buttgenbachite, Cu36CL7.8(NO3)1.3(SO4)0.35(OH)62.2 .5.2H2O and a re-examination of the crystal chemistry of the buttgenbachite - connellite series. Mineralogical Magazine, 67(1), 47-60.
  • Emseis, P., Hibbs, D., Leverett, P., Williams, P. (2003). Crystal and molecular structures of three salts of delta-beta1-[Co(R,R-picchxn)(R-phe)]2+ (picchxn = N, N1-di(2-picolyl)-1,2-diamino-cyclohexane;phe=phenylalaninato(1-)). Journal of Coordination Chemistry, 56(5), 389-395.
  • Hibbs, D., Austin-Woods, C., Platts, J., Overgaard, J., Turner, P. (2003). Experimental and theoretical charge density study of the neurotransmitter Taurine. Chemistry: A European Journal, 9(5), 1075-1084. [More Information]
  • Hibbs, D., Hanrahan, J., Hursthouse, M., Knight, D., Overgaard, J., Turner, P., Piltz, R., Waller, M. (2003). Experimental and theoretical charge distribution in (Z)-N-methyl-C-phenylnitrone. Organic and Biomolecular Chemistry, 11(6), 1034-1040.
  • Overgaard, J., Hibbs, D., Rentschler, E., Timco, G., Larsen, F. (2003). Experimental and theoretical electron density distribution and magnetic properties of the buterfly-like complex [Fe4O2(O2CCMe3)8(NC5H4Me)2].2CH3CN. Inorganic Chemistry, 42(23), 7593-7601.
  • Waller, M., Hibbs, D., Overgaard, J., Hanrahan, J., Hambley, T. (2003). Flavone. Acta Crystallographica. Section E: Structure Reports Online, 59(6), o767-o768.
  • Overgaard, J., Waller, M., Platts, J., Hibbs, D. (2003). Influence of Crystal Effects on Molecular Charge Densities in a Study of 9-Ethynyl-9-fluorenol. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 107(50), 11201-11208.
  • Nyerges, M., Bendell, D., Arany, A., Hibbs, D., Coles, S., Hursthouse, M., Groundwater, P., Meth-Cohn, O. (2003). Silver acetate catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides. Synlett, 7, 947-950.
  • Emseis, P., Hibbs, D., Reddy, N., Leverett, P., Williams, P. (2003). Solid state and solution structures of complexes of the type delta-beta2-[Co(R,R-picchxn)(R-aa)]2+ [picchxn = N, N1-di(2-picolyl)-1,2-diaminocyclohexane;aa=aromatic aminoacidate. Journal of Coordination Chemistry, 56(8), 661-675.
  • Hibbs, D., Overgaard, J., Hambley, T., Gatti, C. (2003). The electron density in flavones I. Baicalein. New Journal of Chemistry, 27(9), 1392-1398.
  • Bruce, S., Hibbs, D., Jones, C., Steed, J., Thomas, R., Williams, T. (2003). The synthesis and structural characterisation of 2-arsa- and 2-stiba-1,3-dionato complexes of s- and p-block elements. New Journal of Chemistry, 27(3), 466-474.
  • Hibbs, D., Overgaard, J., Piltz, R. (2003). X-N charge density analysis of the hydrogne bonding motif in 1-(2-hydroxy-5-nitrophenyl)ethanone. Organic and Biomolecular Chemistry, 1(7), 1191-1198.
  • Coles, S., Hibbs, D., Hursthouse, M., Beckett, M., Owen, P., Varma, K. (2002). Bis(triphenylstannyl)borate toluene solvate. Acta Crystallographica. Section E: Structure Reports Online, 58(2), m65-m67.
  • Hibbs, D., Leverett, P., Williams, P. (2002). Buttgenbachite from Bisbee, Arizona, USA: a single-crystal X-ray study. Neues Jahrbuch fuer Mineralogie. Monatshefte, 2002 (5), 225-240.
  • Doble, D., Blake, A., Hibbs, D., Jackson, M., Li, W., Schröder, M. (2002). Effect of Partial Hydrolysis in Switching the Mode of Inter-molecular Bonding between Metal Complexes. Zeitschrift fuer Anorganische und Allgemeine Chemie, 628(11), 2311-2314.
  • Hibbs, D., Kolitsch, U., Leverett, P., Sharpe, J., Williams, P. (2002). Hoganite and paceite, two new acetate minerals from the Potosi mine, Broken Hill, Australia. Mineralogical Magazine, 66(3), 459-464.
  • Hambley, T., Hibbs, D., Turner, P., Howard, S., Hursthouse, M. (2002). Insights into bonding and hydrogen bond directionality in thioacetamide from the experimental charge distribution. Journal of the Chemical Society Perkin Transactions 2, 2(2002), 235-239.
  • Hall, M., Failes, T., Hibbs, D., Hambley, T. (2002). Structural Investigations of Palladium(II) and Platinum(II) Complexes of Salicylhydroxamic Acid. Inorganic Chemistry, 41(5), 1223-1228.
  • Daia, G., Gabbutt, C., Hepworth, J., Heron, B., Hibbs, D., Hursthouse, M. (2002). Synthesis and cycloadditions of 9H-furo[3,4-b][1]benzo(thio)pyran-9-ones furan ring formation by a novel hydrolytically induced cycloreversion. Tetrahedron Letters, 43(25), 4507-4510.
  • Hibbs, D., Coles, S., Hursthouse, M. (2001). 5-tert-Butylperoxy-5-(oxiran-2-yl)-1-(prop-2-ynyl)-pyrrolidin-2-one. Acta Crystallographica. Section E: Structure Reports Online, E57.
  • Hall, B., Hanrahan, J., Johnston, G., Hambley, T., Hibbs, D. (2001). 6-Methylflavone. Acta Crystallographica. Section E: Structure Reports Online, E57.
  • Jones, A., Knight, D., Hibbs, D. (2001). A stereochemically flexible approach to pyrrolidines based on 5-endo-trig iodocyclisations of homoallylic sulfonamides. Royal Chemical Society. Journal. Perkin Transactions 1, 10, 1182-1203.
  • Platts, J., Hibbs, D., Hambley, T., Hall, M. (2001). Calculation of the hydrophobicity of platinum drugs. Journal of Medicinal Chemistry, 44(3), 472-474.
  • Hibbs, D., Bell, N., Coles, S., Constable, C., Hursthouse, M., Mansor, R., Raper, E., Sammon, C. (2001). Complexes of heterocyclic thiones and Group 12 metals Part 5. Reactions of 1,3-thiazolidine-2-thione and benzo-1,3-thiazoline-2-thione with mercury(II) halides in a 2:1 ratio. Crystal structures of bis(1,3-thiazolidine-2-thione) mercury(II) bromide and bi. Inorganica Chimica Acta, 323, 69-77.
  • Martin, L., Turner, S., Day, P., Guionneau, P., Howard, J., Hibbs, D., Light, M., Hursthouse, M., Uruichi, M., Yakushi, K. (2001). Crystal Chemistry and Physical Properties of Superconducting and Semiconducting Charge Transfer Salts of the Type (BEDT-TTF)4[AIMIII (C2O4)3]âPhCN (AI = H3O, NH4, K; MIII = Cr, Fe, Co, Al; BEDT-TTF = Bis(ethylenedithio)tetrathiafulvalene). Inorganic Chemistry, 40(6), 1363-1371.

Conferences

  • Shankar, G., Charleston, M., Murray, M., Hibbs, D. (2006). Phylogenetic analysis of cytochrome P450 structures. BIOINFORMATICS AUSTRALIA 2006, Sydney: NSW Office for Science and Medical Research.

Patents

  • Hibbs, D., Salam, N., Roubin, R., Matin, A., Gavande, N. (2009). PPAR Agonists. Patent No. 2009026658. World.
  • Hibbs, D., Salam, N., Huang, H., Roubin, R., Matin, A., Gavande, N., Nammi, S., Kim, M. (2009). Preparation of flavonoid PPAR agonists. Patent No. 2009026657. World.

2013

  • Raguine, L., Ali, M., Bender, V., Diefenbach, E., Doddareddy, M., Hibbs, D., Manolios, N. (2013). Alanine Scan of an Immunosuppressive Peptide (CP): Analysis of Structure-Function Relationships. Chemical Biology & Drug Design, 81(2), 167-174. [More Information]
  • Ng, N., Leverett, P., Hibbs, D., Yang, Q., Bulanadi, J., Wu, M., Aldrich-Wright, J. (2013). The antimicrobial properties of some copper(ii) and platinum(ii) 1,10-phenanthroline complexes. Dalton Transactions, 42(9), 3196-3209. [More Information]
  • Matin, A., Doddareddy, M., Gavande, N., Nammi, S., Groundwater, P., Roubin, R., Hibbs, D. (2013). The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists. Bioorganic and Medicinal Chemistry, 21(3), 766-778. [More Information]
  • Banister, S., Wilkinson, S., Longworth, M., Stuart, J., Apetz, N., English, K., Brooker, L., Goebel, C., Hibbs, D., Glass, M., McGregor, I., Kassiou, M., et al (2013). The Synthesis and Pharmacological Evaluation of Adamantane-Derived Indoles: Cannabimimetic Drugs of Abuse. ACS Chemical Neuroscience, 4(7), 1081-1092. [More Information]

2012

  • Banister, S., Wilkinson, S., Hanani, R., Reynolds, A., Hibbs, D., Kassiou, M. (2012). A practical, multigram synthesis of the 2-(2-(4-alkoxyphenyl)-5,7-dimethylpy-razolo[1,5-a]pyrimidin-3-yl)acetamide (DPA) class of high affinity translocator protein (TSPO) ligands. Tetrahedron Letters, 53(29), 3780-3783. [More Information]
  • Banister, S., Manoli, M., Doddareddy, M., Hibbs, D., Kassiou, M. (2012). A σ1 receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDS). Bioorganic & Medicinal Chemistry Letters, 22(19), 6053-6058. [More Information]
  • Cui, P., Rawling, T., Bourget, K., Kim, T., Duke, C., Doddareddy, M., Hibbs, D., Zhou, F., Tattam, B., Petrovic, N., Murray, M. (2012). Antiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2. Journal of Medicinal Chemistry, 55(16), 7163-7172. [More Information]
  • Beinat, C., Banister, S., Prehn, S., Doddareddy, M., Hibbs, D., Sako, M., Collins (Chebib), M., Tran, T., Al-Muhtasib, N., Xiao, Y., Kassiou, M. (2012). Consequences of linker length alteration of the alpha7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333. Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, 22(7), 2380-2384. [More Information]
  • Manetsch, M., Ramsay, E., King, E., Seidel, P., Che, A., Ge, Q., Hibbs, D., Newton, R., Ammit, A. (2012). Corticosteroids and B2-agonists upregulate mitogen-activated protein kinase phosphatase 1: in vitro mechanisms. British Journal of Pharmacology, 166(7), 2049-2059. [More Information]
  • Petch, D., Anderson, R., Cunningham, A., George, S., Hibbs, D., Liu, R., Mackay, S., Paul, A., Small, D., Groundwater, P. (2012). Design and synthesis of EGFR dimerization inhibitors and evaluation of their potential in the treatment of psoriasis. Bioorganic & Medicinal Chemistry Letters, 20(19), 5901-5914. [More Information]
  • Zhao, Y., Hibbs, D., Groundwater, P., Wassef, A. (2012). Diethyl 4-(4-acetamidophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Acta Crystallographica. Section E: Structure Reports Online, 68(8), 1-8. [More Information]
  • Failes, T., Mitic, G., Abdel-Halim, H., Po'uha, S., Liu, M., Hibbs, D., Kavallaris, M. (2012). Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells. PLoS One, 7(2), 1-11. [More Information]
  • Nguyen, T., Howard, S., Hanrahan, J., Groundwater, P., Platts, J., Hibbs, D. (2012). Experimental and Theoretical Charge Density Distribution in a Host-Guest System: Synthetic Terephthaloyl Receptor Complexed to Adipic Acid. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 116, 5618-5628. [More Information]
  • Nguyen, T., Groundwater, P., Platts, J., Hibbs, D. (2012). Experimental and theoretical charge density studies of 8-hydroxyquinoline cocrystallized with salicylic acid. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 116(13), 3420-3427. [More Information]
  • Ghassabian, S., Rawling, T., Zhou, F., Doddareddy, M., Tattam, B., Hibbs, D., Edwards, R., Cui, P., Murray, M. (2012). Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites. Biochemical Pharmacology, 84(2), 215-223. [More Information]

2011

  • Zhao, Y., Groundwater, P., Hibbs, D., Nguyen, P., Narlawar, R. (2011). (1E,4Z,6E)-5-Hydroxy-1,7-bis(2-meth-oxyphenyl)-1,4,6-heptatrien-3-one. Acta Crystallographica. Section E: Structure Reports Online, E67(8), o1885. [More Information]
  • Orlandi, P., Demartin, F., Pasero, M., Leverett, P., Williams, P., Hibbs, D. (2011). Gelosaite, BiMo6+ (2-5x)Mo5+ 6xO7(OH)·H2O (0 ≤ x ≤ 0.4), a new mineral from Su Senargiu (CA), Sardinia, Italy, and a second occurrence from Kingsgate, New England, Australia. American Mineralogist, 96, 268-273. [More Information]
  • Abdel-Halim, H., Traini, D., Hibbs, D., Gaisford, S., Young, P. (2011). Modelling of molecular phase transitions in pharmaceutical inhalation compounds: an in silico approach. European Journal of Pharmaceutics and Biopharmaceutics, 78(1), 83-89. [More Information]
  • Lo, A., Salam, N., Hibbs, D., Rutledge, P., Todd, M. (2011). Polyamide-Scorpion Cyclam Lexitropsins Selectively Bind AT-Rich DNA Independently of the Nature of the Coordinated Metal. PLoS One, 6(5), e17446-1-e17446-13. [More Information]
  • Sciberras, M., Leverett, P., Williams, P., Hibbs, D., Roberts, A., Grice, J. (2011). The Single-Crystal X-Ray Structure of Gagarinite-(Ce). Canadian Mineralogist: crystallography, geochemistry, mineralogy, petrology, mineral deposits, 49, 1111-1114. [More Information]

2010

  • Ning, F., Anderson, R., Hibbs, D., Groundwater, P. (2010). A new, one-step synthesis of 1-heteroaryl-2-alkylaminoethanols. Tetrahedron Letters, 51, 843-845.
  • Nebot, N., Crettol, S., D'Esposito, F., Tattam, B., Hibbs, D., Murray, M. (2010). Participation of CYP2C8 and CYP3A4 in the N-demethylation of imatinib in human hepatic microsomes. British Journal of Pharmacology, 161(5), 1059-1069. [More Information]
  • Reynolds, A., Hanani, R., Hibbs, D., Damont, A., Da Pozzo, E., Selleri, S., Dolle, F., Martini, C., Kassiou, M. (2010). Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO). Bioorganic and Medicinal Chemistry Letters: the tetrahedron journal for research at the interface of chemistry and biology, 20(19), 5799-5802. [More Information]

2009

  • Matin, A., Gavande, N., Kim, M., Yang, N., Salam, N., Hanrahan, J., Roubin, R., Hibbs, D. (2009). 7-Hydroxy-benzopyran-4-one Derivatives: A Novel Pharmacophore of Peroxisome Proliferator-Activated Receptor and - (PPAR and ) Dual Agonists. Journal of Medicinal Chemistry, 52(21), 6835-6850. [More Information]
  • Hibbs, D., Salam, N., Roubin, R., Matin, A., Gavande, N. (2009). PPAR Agonists. Patent No. 2009026658. World.
  • Hibbs, D., Salam, N., Huang, H., Roubin, R., Matin, A., Gavande, N., Nammi, S., Kim, M. (2009). Preparation of flavonoid PPAR agonists. Patent No. 2009026657. World.
  • Mewett, K., Fernandez, S., Pasricha, A., Pong, A., Devenish, S., Hibbs, D., Collins (Chebib), M., Johnston, G., Hanrahan, J. (2009). Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors. Bioorganic and Medicinal Chemistry. [More Information]
  • Hall, M., Salam, N., Hellawell, J., Fales, H., Kensler, C., Ludwig, J., Szakacs, G., Hibbs, D., Gottesman, M. (2009). Synthesis, Activity, and Pharmacophore Development for Isatin-Beta-thiosemicarbazones with Selective Activity toward Multidrug-Resistant Cells. Journal of Medicinal Chemistry, 52(10), 3191-3204. [More Information]

2008

  • Abdel-Halim, H., Hanrahan, J., Hibbs, D., Johnston, G., Collins (Chebib), M. (2008). A molecular basis for agonist and antagonist actions at GABA(C) receptors. Chemical Biology and Drug Design (Print), 71(4), 306-327. [More Information]
  • Liaw, T., Salam, N., McKay, M., Cunningham, A., Hibbs, D., Kavallaris, M. (2008). Class I β-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions. Molecular Cancer Therapeutics, 7(10), 3150-3159. [More Information]
  • Kumar, R., Collins (Chebib), M., Hibbs, D., Kim, H., Johnston, G., Salam, N., Hanrahan, J. (2008). Novel gamma-aminobutyric acid rho(1) receptor antagonists; Synthesis, pharmacological activity and structure-activity relationships. Journal of Medicinal Chemistry, 51(13), 3825-3840. [More Information]
  • Salam, N., Huang, H., Kota, B., Kim, M., Li, Y., Hibbs, D. (2008). Novel PPAR-gamma agonists identified from a natural product library: A virtual screening, induced-fit docking and biological assay study. Chemical Biology and Drug Design (Print), 71(1), 57-70. [More Information]

2007

  • Shankar, G., Charleston, M., Murray, M., Hibbs, D. (2007). A structural and phylogenetic analysis of cytochrome P450. In Damjana Rozman (Eds.), Proceedings of the 15th International Conference on Cytochromes P450: Biochemistry, Biophysics and Functional Genomics, (pp. 75-80). Bologna, Italy: Medimond.
  • Overgaard, J., Waller, M., Piltz, R., Platts, J., Emseis, P., Leverett, P., Williams, P., Hibbs, D. (2007). Experimental and Theoretical Charge Density Distribution in Two Ternary Cobalt(III) Complexes of Aromatic Amino Acids. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 111(40), 10123-10133. [More Information]
  • Overgaard, J., Turel, I., Hibbs, D. (2007). Experimental electron density study of a complex between copper(ii) and the antibacterial quinolone family member ciprofloxacin. Dalton Transactions: an international journal of inorganic, organometallic and bioinorganic chemistry, 2007 (21), 2171-2178. [More Information]
  • Pavel, D., Hibbs, D., Shanks, R. (2007). Review of main chain liquid crystalline polymers. In Firas Awaja (Eds.), Advanced Research in Polymer Science, (pp. 65-84). Kerala, India: Transworld Research Network.
  • Battle, A., Edwards, P., Haigh, R., Hibbs, D., Li, D., Liddiard, S., Newman, P. (2007). Synthesis and Characterization of Iron(II) Complexes of 10- and 11-Membered Triphosphamacrocycles. Organometallics, 26(2), 377-386.
  • CLISSOLD, M., Leverett, P., Williams, P., Hibbs, D., NICKEL, E. (2007). The structure of gillardite, the Ni-analogue of herbertsmithite, from Widgiemooltha, Western Australia. Canadian Mineralogist: crystallography, geochemistry, mineralogy, petrology, mineral deposits, 45(2), 317-320.

2006

  • Starke-Peterkovic, T., Turner, N., Vitha, M., Waller, M., Hibbs, D., Clarke, R. (2006). Cholesterol effect on the dipole potential of lipid membranes. Biophysical Journal, 90(11), 4060-4070. [More Information]
  • Waller, M., Robertazzi, A., Platts, J., Hibbs, D., Williams, P. (2006). Hybrid density functional theory for pi-stacking interactions: application to benzenes, pyridines, and DNA bases. Journal of Computational Chemistry, 27(4), 491-504. [More Information]
  • Waller, M., Howard, S., Platts, J., Piltz, R., Willock, D., Hibbs, D. (2006). Novel properties from experimental charge densities: an application to the Zwitterionic neurotransmitter taurine. Chemistry: A European Journal, 12(29), 7603-7614. [More Information]
  • Shankar, G., Charleston, M., Murray, M., Hibbs, D. (2006). Phylogenetic analysis of cytochrome P450 structures. BIOINFORMATICS AUSTRALIA 2006, Sydney: NSW Office for Science and Medical Research.
  • Battle, A., Choi, R., Hibbs, D., Hambley, T. (2006). Platinum(IV) analogues of AMD473 (cis-[PtCl2(NH3)(2-picoline)]): preparative, structural, and electrochemical studies. Inorganic Chemistry, 45(16), 6317-6322. [More Information]
  • Howard, S., Hibbs, D., Amoroso, A., Platts, J. (2006). Quantum-Chemical Design of Cryptand-like Ditopic Salt Binders. Journal of Chemical Theory and Computation, 2(2), 354-363.
  • Ali, M., Salam, N., Amon, M., Bender, V., Hibbs, D., Manolios, N. (2006). T-cell antigen receptor-alpha chain transmembrane peptides: correlation between structure and function. International Journal of Peptide Research and Therapeutics, 12(3), 261-267.

2005

  • Hibbs, D., Howard, S., Huke, J., Waller, M. (2005). A new orbital-based model for the analysis of experimental molecular charge densities: an application to (Z)-N-methyl-C-phenylnitrone. Physical Chemistry Chemical Physics, 7(8), 1772. [More Information]
  • Bell, N., Bradley, C., Broughton, R., Coles, S., Hibbs, D., Hursthouse, M., Ray, A., Simmonds, D., Thorpe, S. (2005). Comparison of the structure property relationships in LB films of zwitterionic TCNQ adducts. Journal of Materials Chemistry, 15(14), 1437-1445.
  • Nguyen, T., Hibbs, D., Howard, S. (2005). Conformations, Energies, and Intramolecular Hydrogen Bonds in Dicarboxylic Acids: Implications for the Design of Synthetic Dicarboxylic Acid Receptors. Journal of Computational Chemistry, 26(12), 1233-1241. [More Information]
  • Hibbs, D., Overgaard, J., Howard, S., Nguyen, T. (2005). Experimental charge density of a potential DHO synthetase inhibitor: dimethyl-trans-2-oxohexahydro-pyrimidine-4,6-dicarboxylate. Organic and Biomolecular Chemistry, 3(3), 441-447. [More Information]
  • Nyerges, M., Bendell, D., Arany, A., Hibbs, D., Coles, S., Hursthouse, M., Groundwater, P., Meth-Cohn, O. (2005). Silver acetate-catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides. Tetrahedron, 61(15), 3745-3753.

2004

  • Hibbs, D., Overgaard, J., Platts, J., Waller, M., Hursthouse, M. (2004). Experimental And Theoretical Charge Density Studies Of Tetrafluorophthalonitrile And Tetrafluoroisophthalonitrile. The Journal of Physical Chemistry Part B: Condensed Matter, Materials, Surfaces, Interfaces and Biophysical, 108(11), 3663-3672.
  • Emseis, P., Failes, T., Hibbs, D., Leverett, P., Williams, P. (2004). Intramolecular Nh-Pi And Pi-Pi Interactions In Ternary Cobalt(III) Complexes Of Aromatic Aminoacids: A Structural And NMR Study. Polyhedron, 23(10), 1749-1767.
  • Allan, R., Greenwood, J., Hambley, T., Hanrahan, J., Hibbs, D., Itani, S., Tran, H., Turner, P. (2004). Studies On Pyridazine Azide Cyclisation Reactions. Organic and Biomolecular Chemistry, 2(12), 1782-8-1788.
  • Duke, R., Collins (Chebib), M., Hibbs, D., Mewett, K., Johnston, G. (2004). Synthesis And Resolution Of 2-Methyl Analogues Of GABA. Tetrahedron-Asymmetry, 15(11), 1745-1751.
  • Overgaard, J., Hibbs, D. (2004). The Experimental Electron Density In Polymorphs A And B Of The Anti-Ulcer Drug Famotidine. Acta Crystallographica Section A: Foundations of Crystallography, 60, 480-487.
  • Emseis, P., Hibbs, D., Leverett, P., Reddy, N., Williams, P. (2004). The structure of Λ-β1-[Co(R,R-picchxn)(S-tyr)]Br2 · 3.5H2O and solution configuration of Λ-β1-[Co(R,R-picchxn)(aromatic S-aminoacidate)]2+ complexes: model systems for the investigation of non-covalent aromatic interactions. Inorganica Chimica Acta, 357(11), 3251-3263. [More Information]
  • Emseis, P., Hibbs, D., Leverett, P., Reddy, N., Williams, P. (2004). Weak Intramolecular Interactions In Perchlorate Salts Of Lambda-Beta(1)- Co(R,R-Picchxn)(R-Aa) (2+) Picchxn = N,N '-Di(2-Picolyl)-1,2-Diaminocyclohexane; Aa = Phenylalaninato(1-), Tyrosinato(1-) And Their Diastereoisomeric Equilibration In Solution. Inorganica Chimica Acta, 357(9), 2669-2676. [More Information]

2003

  • Coogan, M., Haigh, R., Hall, A., Harris, L., Hibbs, D., Jenkins, R., Jones, C., Tomkinson, N. (2003). A new chiral diol derived from tetralone for the complexation of Lewis acids. Tetrahedron, 59(37), 7389-7395.
  • Hibbs, D., Leverett, P., Williams, P. (2003). A single crystal X-ray study of a sulphate-bearing buttgenbachite, Cu36CL7.8(NO3)1.3(SO4)0.35(OH)62.2 .5.2H2O and a re-examination of the crystal chemistry of the buttgenbachite - connellite series. Mineralogical Magazine, 67(1), 47-60.
  • Emseis, P., Hibbs, D., Leverett, P., Williams, P. (2003). Crystal and molecular structures of three salts of delta-beta1-[Co(R,R-picchxn)(R-phe)]2+ (picchxn = N, N1-di(2-picolyl)-1,2-diamino-cyclohexane;phe=phenylalaninato(1-)). Journal of Coordination Chemistry, 56(5), 389-395.
  • Hibbs, D., Austin-Woods, C., Platts, J., Overgaard, J., Turner, P. (2003). Experimental and theoretical charge density study of the neurotransmitter Taurine. Chemistry: A European Journal, 9(5), 1075-1084. [More Information]
  • Hibbs, D., Hanrahan, J., Hursthouse, M., Knight, D., Overgaard, J., Turner, P., Piltz, R., Waller, M. (2003). Experimental and theoretical charge distribution in (Z)-N-methyl-C-phenylnitrone. Organic and Biomolecular Chemistry, 11(6), 1034-1040.
  • Overgaard, J., Hibbs, D., Rentschler, E., Timco, G., Larsen, F. (2003). Experimental and theoretical electron density distribution and magnetic properties of the buterfly-like complex [Fe4O2(O2CCMe3)8(NC5H4Me)2].2CH3CN. Inorganic Chemistry, 42(23), 7593-7601.
  • Waller, M., Hibbs, D., Overgaard, J., Hanrahan, J., Hambley, T. (2003). Flavone. Acta Crystallographica. Section E: Structure Reports Online, 59(6), o767-o768.
  • Overgaard, J., Waller, M., Platts, J., Hibbs, D. (2003). Influence of Crystal Effects on Molecular Charge Densities in a Study of 9-Ethynyl-9-fluorenol. The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 107(50), 11201-11208.
  • Nyerges, M., Bendell, D., Arany, A., Hibbs, D., Coles, S., Hursthouse, M., Groundwater, P., Meth-Cohn, O. (2003). Silver acetate catalysed asymmetric 1,3-dipolar cycloadditions of imines and chiral acrylamides. Synlett, 7, 947-950.
  • Emseis, P., Hibbs, D., Reddy, N., Leverett, P., Williams, P. (2003). Solid state and solution structures of complexes of the type delta-beta2-[Co(R,R-picchxn)(R-aa)]2+ [picchxn = N, N1-di(2-picolyl)-1,2-diaminocyclohexane;aa=aromatic aminoacidate. Journal of Coordination Chemistry, 56(8), 661-675.
  • Hibbs, D., Overgaard, J., Hambley, T., Gatti, C. (2003). The electron density in flavones I. Baicalein. New Journal of Chemistry, 27(9), 1392-1398.
  • Bruce, S., Hibbs, D., Jones, C., Steed, J., Thomas, R., Williams, T. (2003). The synthesis and structural characterisation of 2-arsa- and 2-stiba-1,3-dionato complexes of s- and p-block elements. New Journal of Chemistry, 27(3), 466-474.
  • Hibbs, D., Overgaard, J., Piltz, R. (2003). X-N charge density analysis of the hydrogne bonding motif in 1-(2-hydroxy-5-nitrophenyl)ethanone. Organic and Biomolecular Chemistry, 1(7), 1191-1198.

2002

  • Coles, S., Hibbs, D., Hursthouse, M., Beckett, M., Owen, P., Varma, K. (2002). Bis(triphenylstannyl)borate toluene solvate. Acta Crystallographica. Section E: Structure Reports Online, 58(2), m65-m67.
  • Hibbs, D., Leverett, P., Williams, P. (2002). Buttgenbachite from Bisbee, Arizona, USA: a single-crystal X-ray study. Neues Jahrbuch fuer Mineralogie. Monatshefte, 2002 (5), 225-240.
  • Doble, D., Blake, A., Hibbs, D., Jackson, M., Li, W., Schröder, M. (2002). Effect of Partial Hydrolysis in Switching the Mode of Inter-molecular Bonding between Metal Complexes. Zeitschrift fuer Anorganische und Allgemeine Chemie, 628(11), 2311-2314.
  • Hibbs, D., Kolitsch, U., Leverett, P., Sharpe, J., Williams, P. (2002). Hoganite and paceite, two new acetate minerals from the Potosi mine, Broken Hill, Australia. Mineralogical Magazine, 66(3), 459-464.
  • Hambley, T., Hibbs, D., Turner, P., Howard, S., Hursthouse, M. (2002). Insights into bonding and hydrogen bond directionality in thioacetamide from the experimental charge distribution. Journal of the Chemical Society Perkin Transactions 2, 2(2002), 235-239.
  • Hall, M., Failes, T., Hibbs, D., Hambley, T. (2002). Structural Investigations of Palladium(II) and Platinum(II) Complexes of Salicylhydroxamic Acid. Inorganic Chemistry, 41(5), 1223-1228.
  • Daia, G., Gabbutt, C., Hepworth, J., Heron, B., Hibbs, D., Hursthouse, M. (2002). Synthesis and cycloadditions of 9H-furo[3,4-b][1]benzo(thio)pyran-9-ones furan ring formation by a novel hydrolytically induced cycloreversion. Tetrahedron Letters, 43(25), 4507-4510.

2001

  • Hibbs, D., Coles, S., Hursthouse, M. (2001). 5-tert-Butylperoxy-5-(oxiran-2-yl)-1-(prop-2-ynyl)-pyrrolidin-2-one. Acta Crystallographica. Section E: Structure Reports Online, E57.
  • Hall, B., Hanrahan, J., Johnston, G., Hambley, T., Hibbs, D. (2001). 6-Methylflavone. Acta Crystallographica. Section E: Structure Reports Online, E57.
  • Jones, A., Knight, D., Hibbs, D. (2001). A stereochemically flexible approach to pyrrolidines based on 5-endo-trig iodocyclisations of homoallylic sulfonamides. Royal Chemical Society. Journal. Perkin Transactions 1, 10, 1182-1203.
  • Platts, J., Hibbs, D., Hambley, T., Hall, M. (2001). Calculation of the hydrophobicity of platinum drugs. Journal of Medicinal Chemistry, 44(3), 472-474.
  • Hibbs, D., Bell, N., Coles, S., Constable, C., Hursthouse, M., Mansor, R., Raper, E., Sammon, C. (2001). Complexes of heterocyclic thiones and Group 12 metals Part 5. Reactions of 1,3-thiazolidine-2-thione and benzo-1,3-thiazoline-2-thione with mercury(II) halides in a 2:1 ratio. Crystal structures of bis(1,3-thiazolidine-2-thione) mercury(II) bromide and bi. Inorganica Chimica Acta, 323, 69-77.
  • Martin, L., Turner, S., Day, P., Guionneau, P., Howard, J., Hibbs, D., Light, M., Hursthouse, M., Uruichi, M., Yakushi, K. (2001). Crystal Chemistry and Physical Properties of Superconducting and Semiconducting Charge Transfer Salts of the Type (BEDT-TTF)4[AIMIII (C2O4)3]âPhCN (AI = H3O, NH4, K; MIII = Cr, Fe, Co, Al; BEDT-TTF = Bis(ethylenedithio)tetrathiafulvalene). Inorganic Chemistry, 40(6), 1363-1371.

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