2012

• Huang, S., Lewis, T., Lummis, S., Thompson, A., Chebib, M., Johnston, G., Duke, R. Mixed antagonistic effects of the ginkgolides at recombinant human ρ(1)GABA(C) receptors. Neuropharmacology. 2012; 63:1127-1139. [Abstract]
• Yamamoto, I., Absalom, N., Carland, J., Doddareddy, M., Gavande, N., Johnston, G., Hanrahan, J., Chebib, M. Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABA(C) ρ(1) Receptors. ACS Chemical Neuroscience. 2012; 3:665-673. [Abstract]
• Karim, N., Wellendorph, P., Absalom, N., Bang, L., Jensen, M., Hansen, M., Lee, H., Johnston, G., Hanrahan, J., Chebib, M. Low nanomolar GABA effects at extrasynaptic α4β1/β3δ GABA(A) receptor subtypes indicate a different binding mode for GABA at these receptors. Biochemical Pharmacology. 2012; 84:549-557. [Abstract]
• Absalom, N., Eghorn, L., Villumsen, I., Karim, N., Bay, T., Olsen, J., Knudsen, G., Br��uner-Osborne, H., Fr��lund, B., Clausen, R., Chebib, M., Wellendorph, P. α4βδ GABAA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB). Proceedings of the National Academy of Sciences. 2012; 109:13404–13409. [Abstract]
• Ambrus, J., Halliday, J., Kanizaj, N., Absalom, N., Harpsøe, K., Balle, T., Chebib, M., McLeod, M. Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides. Chemical Communications. 2012; 48:6699-6701. [Abstract]
• Beinat, C., Banister, S., van Prehn, S., Doddareddy, M., Hibbs, D., Sako, M., Chebib, M., Tran, T., Al-Muhtasib, N., Xiao, Y., Kassiou, M. Consequences of linker length alteration of the α7 nicotinic acetylcholine receptor (nAChR) agonist, SEN12333. Bioorganic & Medicinal Chemistry Letters. 2012; 22:2380-2384. [Abstract]
• Yamamoto, I., Carland, J., Locock, K., Gavande, N., Absalom, N., Hanrahan, J., Allan, R., Johnston, G., Collins, M. Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the ρ1 Receptor. ACS Chemical Neuroscience. 2012; 3:293–301.
• Fernandez, S., Karim, N., Mewett, K., Chebib, M., Johnston, G., Hanrahan, J. Flavan-3-ol esters: new agents for exploring modulatory sites on GABA(A) receptors. British Journal of Pharmacology. 2012; 165:965-977. [Abstract]
• Karim, N., Curmi, J., Gavande, N., Johnston, G., Hanrahan, J., Tierney, M., Chebib, M. 2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors. British journal of pharmacology. 2012; 165:880-96. [Abstract]
• Yamamoto, I., Jordan, M., Gavande, N., Doddareddy, M., Chebib, M., Hunter, L. The enantiomers of syn-2,3-difluoro-4-aminobutyric acid elicit opposite responses at the GABA(C) receptor. Chemical communications (Cambridge, England). 2012; 48:829-31. [Abstract]
• Pan, Y., Gerasimov, M., Kvist, T., Wellendorph, P., Madsen, K., Pera, E., Lee, H., Schousboe, A., Chebib, M., Bräuner-Osborne, H., Craft, C., Brodie, J., Schiffer, W., Dewey, S., Miller, S., Silverman, R. (1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction. Journal of medicinal chemistry. 2012; 55:357-66. [Abstract]
• Cheng, Z., Chebib, M., Schmid, K. Identification of GABA receptors in chick cornea. Molecular Vision. 2012; 18:1107-1114. [Abstract]

2011

• Karim, N., Gavande, N., Wellendorph, P., Johnston, G., Hanrahan, J., Chebib, M. 3-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABA(A) receptor subtypes. Biochemical pharmacology. 2011; 82:1971-83. [Abstract]
• Xie, A., Yan, J., Yue, L., Feng, F., Mir, F., Abdel-Halim, H., Chebib, M., Le Breton, G., Standaert, R., Qian, H., Pepperberg, D. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-p1 Receptors. Molecular Pharmacology. 2011; 80:965-978. [Abstract]
• Loscalzo, L., Yow, T., Wasowski, C., Chebib, M., Marder, M. Hesperidin induces antinociceptive effect in mice and its aglicone, hesperetin, binds to ??-opioid receptor and inhibits GIRK1/2 currents. Pharmacology, biochemistry, and behavior. 2011; 99:333-41. [Abstract]
• Gavande, N., Karim, N., Johnston, G., Hanrahan, J., Chebib, M. Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABA(A) Receptors. ChemMedChem. 2011; 6:1340-6, 1317. [Abstract]
• Yamamoto, I., Deniau, G., Gavande, N., Chebib, M., Johnston, G., O'Hagan, D. Agonist responses of (R)- and (S)-3-fluoro-??-aminobutyric acids suggest an enantiomeric fold for GABA binding to GABA(C) receptors. Chemical communications (Cambridge, England). 2011; 47:7956-8. [Abstract]
• Cheng, Z., Chebib, M., Schmid, K. rho(1) GABA(C) receptors are expressed in fibrous and cartilaginous layers of chick sclera and located on sclera fibroblasts and chondrocytes. Journal of neurochemistry. 2011; 118:281-7. [Abstract]
• Yow, T., Pera, E., Absalom, N., Heblinski, M., Johnston, G., Hanrahan, J., Chebib, M. Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. British journal of pharmacology. 2011; 163:1017-33. [Abstract]
• Hanrahan, J., Chebib, M., Johnston, G. Flavonoid modulation of GABA(A) receptors. British Journal of Pharmacology. 2011; 163:234-245. [Abstract]
• Wong, S., Chebib, M., Haqshenas, G., Loveland, B., Gowans, E. Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes. Virology. 2011; 412:83-90. [Abstract]
• Ng, C., Kim, H., Gavande, N., Yamamoto, I., Kumar, R., Mewett, K., Johnston, G., Hanrahan, J., Chebib, M. Medicinal chemistry of ρ GABAC receptors. Future Medicinal Chemistry. 2011; 3:197-209. [Abstract]
• Gavande, N., Yamamoto, I., Salam, N., Ai, T., Burden, P., Johnston, G., Hanrahan, J., Collins, M. Novel Cyclic Phosphinic Acids as GABAC ρ Receptor Antagonists: Design, Synthesis, and Pharmacology. ACS Medicinal Chemistry Letters. 2011; 2:11-16.

2010

• Johnston, G., Chebib, M., Hanrahan, J., Mewett, K. Neurochemicals for the Investigation of GABA(C) Receptors. Neurochemical research. 2010; 35:1970-7. [Abstract]
• Gavande, N., Johnston, G., Hanrahan, J., Chebib, M. Microwave-enhanced synthesis of 2,3,6-trisubstituted pyridazines: application to four-step synthesis of gabazine (SR-95531). Organic & biomolecular chemistry. 2010; 8:4131-6. [Abstract]
• Quek, G., Lin, D., Halliday, J., Absalom, N., Ambrus, J., Thompson, A., Lochner, M., Lummis, S., McLeod, M., Collins, M. Identifying the Binding Site of Novel Methyllycaconitine (MLA) Analogs at α4β2 Nicotinic Acetylcholine Receptors. ACS Chemical Neuroscience. 2010; 1:796-809.
• Halliday, J., Collins, M., McLeod, M. Synthesis and biological evaluation of a new family of constrained azabicyclic homocholine analogues. Australian Journal of Chemistry. 2010; 63:808-812.

2009

• Mewett, K., Fernandez, S., Pasricha, A., Pong, A., Devenish, S., Hibbs, D., Chebib, M., Johnston, G., Hanrahan, J. Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABAA receptors. Bioorganic & Medicinal Chemistry. 2009; 17:7156-7173. [Abstract]
• Fernandez, S., Nguyen, M., Yow, T., Chu, C., Johnston, G., Hanrahan, J., Chebib, M. The Flavonoid Glycosides, Myricitrin, Gossypin and Naringin Exert Anxiolytic Action in Mice. Neurochemical research. 2009; 34:1867-75. [Abstract]
• McIntosh, J., Absalom, N., Chebib, M., Elgoyhen, A., Vincler, M. Alpha9 nicotinic acetylcholine receptors and the treatment of pain. Biochemical pharmacology. 2009; 78:693-702. [Abstract]
• Chebib, M., Gavande, N., Wong, K., Park, A., Premoli, I., Mewett, K., Allan, R., Duke, R., Johnston, G., Hanrahan, J. Guanidino Acids Act as rho1 GABA(C) Receptor Antagonists. Neurochemical research. 2009; 34:1704-11. [Abstract]
• MacRaild, C., Illesinghe, J., van Lierop, B., Townsend, A., Chebib, M., Livett, B., Robinson, A., Norton, R. Structure and activity of (2,8)-dicarba-(3,12)-cystino alpha-ImI, an alpha-conotoxin containing a nonreducible cystine analogue. Journal of medicinal chemistry. 2009; 52:755-762. [Abstract]
• Chebib, M., Hinton, T., Schmid, K., Brinkworth, D., Qian, H., Matos, S., Kim, H., Abdel-Halim, H., Kumar, R., Johnston, G., Hanrahan, J. Novel, potent and selective GABAC antagonists inhibit myopia development and facilitate learning and memory. The Journal of pharmacology and experimental therapeutics. 2009; 328:448-57. [Abstract]

2008

• Fernandez, S., Mewett, K., Hanrahan, J., Chebib, M., Johnston, G. Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice. Neuropharmacology. 2008; 55:900-7. [Abstract]
• Kumar, R., Chebib, M., Hibbs, D., Kim, H., Johnston, G., Salam, N., Hanrahan, J. Novel gamma-Aminobutyric Acid rho1 Receptor Antagonists; Synthesis, Pharmacological Activity and Structure-Activity Relationships. Journal of medicinal chemistry. 2008; 51:3825-40. [Abstract]
• Abdel-Halim, H., Hanrahan, J., Hibbs, D., Johnston, G., Chebib, M. A molecular basis for agonist and antagonist actions at GABA(C) receptors. Chemical Biology & Drug Design. 2008; 71:306-327. [Abstract]
• Carland, J., Johnston, G., Chebib, M. Relative impact of residues at the intracellular and extracellular ends of the human GABA(C) rho1 receptor M2 domain on picrotoxinin activity. European journal of pharmacology. 2008; 580:27-35. [Abstract]
• Hinton, T., Chebib, M., Johnston, G. Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA(C) receptors. Bioorganic & medicinal chemistry letters. 2008; 18:402-4. [Abstract]

2007

• Gurney, H., Wong, M., Balleine, R., Rivory, L., McLachlan, A., Hoskins, J., Wilcken, N., Clarke, C., Mann, G., Collins, M., Delforce, S., Lynch, K., Schran, H. Imatinib Disposition and ABCB1 (MDR1, P-Glycoprotein) Genotype. Clinical Pharmacology and Therapeutics. 2007; 82:33-40. [Abstract]
• Small, D., Maksel, D., Kerr, M., Ng, J., Hou, X., Chu, C., Mehrani, H., Unabia, S., Azari, M., Loiacono, R., Aguilar, M., Chebib, M. The beta-amyloid protein of Alzheimer's disease binds to membrane lipids but does not bind to the alpha7 nicotinic acetylcholine receptor. Journal of Neurochemistry. 2007; 101:1527-1538. [Abstract]
• Chebib, M., Hanrahan, J., Kumar, R., Mewett, K., Morriss, G., Wooller, S., Johnston, G. (3-Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonists. Neuropharmacology. 2007; 52:779-87. [Abstract]