Chronotherapy for hypertension in obstructive sleep apnea
Summary
This study will establish whether chronotherapy (the timing of medication ingestion) improves blood pressure control in hypertensive OSA patients.
Supervisor(s)
Research Location
Camperdown - Woolcock Institute of Medical Research
Program Type
Masters/PHD
Synopsis
Obstructive Sleep Apnea (OSA) is a well known cause of hypertension, particularly during sleep and an elevated blood pressure during sleep is particularly strongly associated with cardiovascular mortality. High blood pressure in patients with OSA is known to improve with both pharmacological treatment and treatment of the underlying sleep apnea using continuous positive airway pressure (CPAP). This study will establish whether chronotherapy (the timing of medication ingestion) improves blood pressure control in hypertensive OSA patients. The results have the potential to alter clinical practice in the treatment of high blood pressure in patients with OSA.
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Keywords
obstructive, chronobiology, CPAP, Sleep apnea, Hypertension, Continuous Positive Airway Pressure
Opportunity ID
The opportunity ID for this research opportunity is: 1118
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