Elucidation of proteins involved in fungal pathogenesis

Summary

This project will investigate proteins up-regulated during mammalian infection by the fungal pathogen Cryptococcus.

Supervisor(s)

Dr Dee Carter

Research Location

School of Molecular Bioscience

Program Type

Masters/PHD

Synopsis

Fungi cause a diverse range of diseases and are very difficult to treat. This project looks at proteins that are made by infectious fungi while they are causing disease in animal cells. Proteins made in particularly high abundance may be essential for the fungus to live and grow in animal tissues. By specifically targeting their production, it should be possible to stop the infection without harming the host cell. This information will therefore be used to design new antifungal drugs.

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Keywords

Cryptococcosis, mycosis, meningitis, pulmonary infection, Proteomics, Cryptococcus, yeast, pathogen, infection, Infectious diseases, Genes in biology & medicine, Infection & immunity

Opportunity ID

The opportunity ID for this research opportunity is: 122