Exercise as an adjuvant to vaccination in HIV+ children
An examination of the effects of exercise prior to vaccination on immune responses in HIV+ children.
Acute exercise tasks performed immediately prior to vaccination have been shown to enhance the response to several vaccines in young healthy adults. The clinical efficacy of using exercise to enhance vaccine responses is dependent on success in populations who produced weak responses to traditional vaccine administration and are thus still at risk from disease. HIV+ children are at high risk for pneumonia, and it has been recommended that all HIV+ children receive the Hib and Pneumococcal-conjugate vaccines. This project will examine the potential clinical applicability of exercise as an adjuvant to vaccination in HIV+ children, including in response to Hib and Pneumococcal vaccines.
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The opportunity ID for this research opportunity is: 1311