Stemming vision loss with stem cells

Summary

Studies to maximise recruitment of hematopoietic stem cells in various experimental models of retinopathy.

Supervisor(s)

Professor Tailoi Chan-Ling

Research Location

Camperdown - School of Medical Sciences - Bosch Institute

Program Type

Masters/PHD

Synopsis

The eye is a wonderful organ for gaining insights into normal developmental mechanisms as well as disease processes. The Retina is an extension of the brain embryologically. As such, studies carried out in the retina can contribute to understanding of the development of the brain. However, the thinness of the retina and the fact that the eye is accessible for experimental manipulation makes it a unique system to gain insights re normal developmental processes. Our lab's specialist interests pertain to understanding the cellular processes and molecular cues that regulate vessel formation, astrocyte and pericyte interaction with the vasculature and the Blood-brain barrier during normal development and disease processes.

Additional Information

Application of neural stem cells and oligodendrocytic precursor cells in experimental models of disease: Current projects in the laboratory aims to investigate the potential application of neural stem/precursor cells in animal models of Multiple Sclerosis and spinal cord injury.

Frequency of circulating vascular precursor cells as a predictor of Age-Realted Macular Degeneration (ARMD): New Project

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Keywords

Age-related macular degeneration, diabetic retinopathy, astrocyte biology, pericytes, Stem cells, retina, Hearing & vision problems, Cell biology, Genes in biology & medicine, Neuroscience & psychology, Retinopathy, prematurity, spinal cord injur, angiogenesis, sight threatening diseases, senses

Opportunity ID

The opportunity ID for this research opportunity is: 160

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