Chemical Hazard Assessment

Summary

Chemical hazard assessment focuses on two research areas; 1) Assessing the toxic effects of occupational chemicals with a particular emphasis on exposure to chemical mixtures and 2) Investigating the mechanism of drugs and other chemicals to cause birth defects.

Supervisor(s)

Dr Diana Oakes

Research Location

School of Medical Sciences, Discipline of Biomedical Science

Program Type

PHD

Synopsis

One area of research interest is in developing/assessing a range of in vivo and in vitro techniques that can be utilised to assess the toxic effects of occupational chemicals with a particular focus on the modulating effects of chemical mixtures.  This allows subsequent risk assessment to be based on biological and toxicological plausibility.    This research presents opportunities for PhD topics that include (in collaboration with Dr Helen Ritchie, Discipline of Biomedical Science, University of Sydney):

1. screening chemical mixtures for possible genotoxic effects/interactions
2. investigating the mechanism by which some drugs and chemiscals cause birth defects.

Keywords

genotoxicity, teratology, DNA damage, toxicology, hypoxia, birth defects, mitochondria., Therapeutics & adverse drug effects, Health & lifestyle

Opportunity ID

The opportunity ID for this research opportunity is: 181