The role of regulatory T Lymphocytes in aberrant human immune responses

Summary

The focus is to phenotypically and functionally characterise T regulatory cells in aberrant immune responses  e.g. autoimmune and allergic diseases.

Supervisor(s)

Professor Ralph Nanan

Research Location

Nepean - Nepean Clinical School

Program Type

PHD

Synopsis

Professor Nanan and his team at The Nepean Clinical School, in Collaboration Sydney have developed  a special research  focus on T regulatory cells in collaboration with A/Prof. Barbara Fazekas at the Centenary Institute and with Groups at the Garvan Institute. T regulatory cells are an important subset of T lymphocytes, which are able to contain immune responses. These cells are believed to play an important role in the development of autoimmune and allergic disorders. At Nepean Clinical School we have access to a variety of patients suffering from these disorders. The aim would be characterize the quantity, function and phenotype of T regulatory cells in these patients.     Together with our collaborators, we have established and published the methodology to conduct this study. The project will involve major techniques in cellular and molecular immunology with a strong emphasis on flow-cytometry.

Keywords

Clinical Immunology, immunopathology, autoimmune disorders, allergy, Infectious diseases, Cell biology, Infection & immunity

Opportunity ID

The opportunity ID for this research opportunity is: 199