Dysregulation of the inflammatory response in diabetes: Its role in poor wound healing

Summary

Diabetes is known to alter inflammatroy response but how this contributes to poor wound healing and other complications of diabetes is not known and will be investigated in this work.

Supervisor(s)

Dr Susan McLennan, Dr Nicholas Shackel, Dr Danqing Min

Research Location

Camperdown - School of Medical Sciences

Program Type

Masters/PHD

Synopsis

Studies in my laboratory investigate the effect of diabetes on inflammatory cell function. We have already shown that diabetes can alter the circulating monocyte and neutrophil phenotype but how this is related to the presence of diabetic complications in particular poor wound healing is not known.

Projects in this area would use a variety of techniques including but not limited to studies at the whole animal level, cell culture, flow cytometry and a variety of molecular and histological techniques.

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Keywords

diabetes, Wound healing, inflammation, miRNA, RNA, Imaging, Macrophage, neutrophil

Opportunity ID

The opportunity ID for this research opportunity is: 231

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