Cartilage Volume assessed by MRI in Osteoarthritis

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Summary

Current studies are focusing on the influence of knee trauma and obesity on cartilage and osteoarthritis outcomes as well as the effect of therapies like glucosamine.

Supervisor(s)

Professor Lyn March

Research Location

North Shore - Institute of Bone and Joint Research

Program Type

PHD

Synopsis

Population surveys of random samples of 45 to 64 year old Australians have found at least 20% of women and 10% of men report a diagnosis of symptomatic osteoarthritis (OA). It becomes more prevalent with advancing age. Currently diagnosis is largely by x-ray, with these radiological changes occurring late in the disease process. MRI allows early diagnosis. Cartilage volume and thickness measured from MRI of the knee can be used to examine both normal and arthritic cartilage in OA patients. We have a large database of knee images of healthy volunteers and OA patients and have a 3T Siemens MRI to further study the epidemiology of OA and effects of various drugs.

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Keywords

osteoarthritis, Magnetic Resonance, Chronic diseases & ageing, Infection & immunity, Movement

Opportunity ID

The opportunity ID for this research opportunity is: 249