Mapping genes for nerve disease
Unfortunately, this opportunity is currently unavailable. Please check back at a later date.
Summary
Our laboratory has an exemplary track record for mapping genes for inherited peripheral neuropathies. Charcot-Marie-Tooth (CMT) neuropathy is a degenerative disorder of the peripheral nerve affecting both the sensory and motor neurons. It is the most common disorder presenting in neurogenetic clinics with one in 2500 people affected. Neurons are the longest cells in the body and degeneration at their ends (axonal degeneration) is a common feature in many neurodegenerative disorders. Distal peripheral neuropathies exemplify this problem. Because of the chronic nature of these disorders the hereditary neuropathies are a poorly recognised and silent health burden with a lifetime cost to Australian measured in billions of dollars. Mapping genes for peripheral neuropathies provides an opportunity to understand of the mechanisms involved in axonal degeneration and important molecules required for peripheral nerve development and function.
Supervisor(s)
Associate Professor Marina Kennerson, Professor Garth Nicholson
Research Location
Program Type
Masters/PHD
Synopsis
Currently there are no new projects available.
Want to find out more?
Browse for other opportunities within the ANZAC Research Institute .
Keywords
peripheral nerve, motor neuron, axonal degeneration, linkage analysis, positional cloning, motor neuropathy, chromosome X
Opportunity ID
The opportunity ID for this research opportunity is: 792
Other opportunities with Professor Garth Nicholson