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Neuroscience/Neuroimmunology Research: Role of antibody in brain immune-mediated diseases

The Institute of Neuromuscular Research (INMR) is part of the Children's Hospital at Westmead (CHW), the largest paediatric centre in NSW, providing the most advanced care and treat more...

Supervisor(s): Brilot-Turville, Fabienne (Dr), Dale, Russell (Professor)

Antibody-Mediated Pain Syndrome (AMPS)

Complex regional pain syndromes (CRPSs) are painful disorders with pathophysiological etiologies associated with neuroinflammation, peripheral nerve damage, central sensitization, more...

Supervisor(s): Parratt, John (Dr), Ng, Karl (Associate Professor)

Display of Viral Surface Glycoprotein on Virus like particles (VPLS) for Structure and Immune Epitope Discovery

Unanchored recombinant soluble monomers are often the proteins used in many structure analyses and immunologic testing. But in reality viral surface glycoproteins are orientated, te more...

Supervisor(s): Lynch, Garry (Dr)

STUDIES OF VARIABLE OR CONSERVED SURFACE PROTEIN SITES OF NEISSERIA MENINGITIDIS AS EPITOPES FOR STRAIN-SPECIFIC VACCINES OR BROAD-STRAIN (UNIVERSAL) VACCINES

The gram-negative Neisseria Meningititis (NM) remains a significant microbial problem and particularly lethal for the very young. Serogroup B strains are particularly troublesome an more...

Supervisor(s): Lynch, Garry (Dr)

Control of complement cascade by labile disulphide bonds

The complement system is a key component of innate immunity that offers sophisticated protection against threats to the host organism. Complement is also an important component of t more...

Supervisor(s): Chiu, Joyce (Dr)

Cell cycle control of DNA repair in lymphoid cells

PhD opportunity in an NHMRC-funded group to determine how cell cycle determines the fidelity of DNA repair in activated B cells in vivo. more...

Supervisor(s): Jolly, Chris (Dr)

ASSESS THE GP GLYCOPROTEIN STRUCTURES OF EBOLA AND MARBURG VIRUS ENVELOPES, THEIR MUCIN-LIKE DOMAINS AND SITES FOR IMMUNE ATTACK

This project extends our published ebola (EBOV) gp's structures, and furthers our studies for immune targeting. Taking a holistic approach our studies aim to examine both the standa more...

Supervisor(s): Lynch, Garry (Dr)

Plasmonics for Protein Attachment

Plasmonics will be used in combination with ellipsometry to investigate the attachment of biomolecules to surfaces. The structure of the attached layers will be investigated using n more...

Supervisor(s): McKenzie, David (Professor)

Proteomic Mapping and Molecular Modelling of Avian H5N1 Influenza Antigen Epitopes Targeted by Human Antibodies

In studying Avian H5N1 Influenza specific Antibodies within Humans the aim is to clearly and definitively identify the respective viral proteins and epitopes targeted by neutralizin more...

Supervisor(s): Lynch, Garry (Dr)

Catalysis of Sustainable Processes

Available projects involve the development of novel catalysts for the generation of hydrogen by splitting water with sunlight, for biomass conversion, for green industrial oxidation more...

Supervisor(s): Masters, Tony (Professor)