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A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)

How invasive cancer cells negotiate the 3D tissue environment

My team uses cell biology approaches to discover the cellular machinery that allows deadly, invasive cancer cells to negotiate the surronding 3D environment. more...

Supervisor(s): O'Neill, Geraldine (Associate Professor)

Determining the functional significance of non-coding DNA variants in genes for complex traits involving gene-environmental interactions

To identify non-protein coding DNA changes in genes that interact with the environment using 2 models – sporadic amyotrophic lateral sclerosis for the vulnerability to environ more...

Supervisor(s): Yu, Bing (Associate Professor)

Dissemination of antibiotic resistance genes in commensal Escherichia coli

This project will examine the Escherichia coli present in the gut of healthy adults who have not been recently exposed to antibiotics to determine the prevalence of antibiotic resis more...

Supervisor(s): Hall, Ruth (Professor)

Coding interaural time differences for sound localisation - the steps beyond the initial binaural comparison

The project addresses the profound problem of how a representation of auditory space is derived in the brain. Specifically, we are asking how timing differences between the two ears more...

Supervisor(s): Koeppl, Christine (Dr)

GENES AND CELL-CELL INTERACTIONS IN CANCER PROGRESSION..

Oncogenes, tumour suppressor genes and cell-cell interactions in cancer: which are important in driving tumour progression and invasion in squamous cell carcinomas? more...

Supervisor(s): Lyons, Guy (Associate Professor)

Neural circuitry of emotion processing disturbance in alcohol use disorder

The PhD students will use a combination of neuropsychological and neuroimaging techniques to study brain-behaviour relationships of addiction. These projects are ideally suited to i more...

Supervisor(s): Morley, Kirsten (Dr)

Link between ATP supply and consumption in the maintenance of the shape of the red blood cell in normal and disease states

The link between the main energy supply (ATP from glycolysis) and its consumption by the cytoskeleton will be studied by using nuclear magnetic resonance (NMR) spectroscopy, compute more...

Supervisor(s): Kuchel, Philip (Emeritus Professor)

Phosphate homeostasis and fungal virulence

Inorganic phosphate (Pi) is an important macronutrient for all living organisms including yeast, and is essential for ATP, phospholipid and protein synthesis, metabolism and signall more...

Supervisor(s): Djordjevic, Julianne (Dr), Sorrell, Tania (Professor)

Improving care standards and costs for spinal trauma patients

The proposed project will undertake Phase Three of this multi-phased project, leveraging from the first two project phases which will have defined both current practice, and practic more...

Supervisor(s): Sharwood, Lisa (Dr)