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A Novel Approach of Inhibiting Pancreatic Cancer Metastasis via Targeting Tumour Micro-Environment Induced Autophagy

Targeting autophagy and metastasis in pancreatic cancer via NDRG1 Pancreatic Cancer (PC) is highly metastatic with the highest mortality of all cancers (~93%). The pancreatic tu more...

Supervisor(s): Sahni, Sumit (Dr)

Identifying new drivers of lung cancer

This project will identify and investigate novel genes mutated in a Kras-induced mouse model of lung adenocarcinoma more...

Supervisor(s): Howell, Viive (Dr), Colvin, Emily (Dr)

Pharmacological targeting of the metastasis suppressor NDRG1 using novel therapeutics

Metastasis is the major killer in cancer, being extremely difficult to treat. This project will elucidate the molecular mechanisms that initiate and sustain metastatic progression, more...

Supervisor(s): Kovacevic, Zaklina (Dr), Richardson, Des (Professor)

Molecular analysis of Hepato-Biliary tumours for prognostic and therapeutic potential

Opportunity to undertake molecular analysis of Hepato-Biliary tumours through the Kolling Institute at RNSH. The HPB Surgical unit at RNSH has a Tumour Bank dating back to 2001. more...

Supervisor(s): Hugh, Thomas J (Professor)

RNA-based biomarkers to understand and predict disease progression

RNA-based biomarkers are becoming increasingly important due to their stability and sensitivity of detection. This project will use in vitro, in vivo and clinical sample analysis b more...

Supervisor(s): Hardikar, Anandwardhan (Associate Professor)