About Dr Stuart Cordwell

As a researcher, I enjoy the freedom a research career provides, success depends heavily on imagination and creativity, yet also on careful analysis. We hope that in some small ways we can improve both the longevity and quality of human life through our discoveries.

Our group is primarily interested in utilizing the tools of proteomics to understand disease processes and discover new targets for protein-based diagnosis of disease and potential vaccine and therapeutic targets.

Stuart Cordwell graduated with a PhD in 1997 and was one of the authors responsible for coining the term ‘proteomics’. He has an international reputation as an innovator in this field. He is Group Leader of both the Microbial Proteomics (SMMB) and Cardiovascular Proteomics (SMS, Bosch Institute) Groups within the University. He took up his current appointment at The University of Sydney in December, 2004. He is also the Deputy Director of the University of Sydney Proteomics Facility. He was previously Director of Research and Development (2002-2004) and Senior Research Fellow (1999-2004) at the Australian Proteome Analysis Facility, Macquarie University. He has co-supervised 7 PhD students and more than 10 Honours students and recently established the first undergraduate Proteomics course in Australia. Stuart has over 60 publications in peer-reviewed journals with an emphasis on the development and application of proteomics tools to solve biomedical problems. He was recently awarded the Selby Research Award for 2006. This award is provided to a young investigator in the Biochemical, Physical or Chemical Sciences at the University of Sydney. He was also Honorary Professor of Proteomics at Yonsei University, Korea (2001-2003). Stuart takes an active role in the wider scientific community – he is Secretary of the Australasian Proteomics Society (APS), a member of the Scientific Advisory Board, Australasian Proteomics Computational Facility (APCF; 2006-), Chair, Education Sub-Committee APS (2004-), part of the Organizing Committee for the Lorne Proteomics Symposium (2004-), AOHUPO Cairns 2008, and HUPO 2010, and he is a past-President of the Australian Electrophoresis and Proteomics Society (2001-2002). He is also a member of the Editorial Board for the field-leading journal, Proteomics. He has been an invited speaker at many national and international meetings to speak on the proteomics of disease, including the Human Proteome Organization (HUPO) Meeting (France, 2002) and the 3rd HUPO Meeting (China, 2004) and is invited again in 2007, the 12th Australian Health and Medical Research Conference (Melbourne, 2006), and the Lorne Proteomics Symposium (2005 and 2003), the Australian Society for Microbiology Meetings 2004 and 2005 and is invited again in 2007, as well as the 4th (2000) and 5th (2002) Siena Meetings (From Genome to Proteome), ComBio 2001 and 2002, Pseudomonas 2001 (Brussels) and 2003 (Quebec City) and the North American Cystic Fibrosis Foundation Meeting (St. Louis, 2004).

Selected publications

  • White, M.Y., Gundry, R.L. and Cordwell, S.J. (2006) When does a fingerprint constitute a diagnostic? The Lancet 368: 971-973. PubMedId: 16980095
  • Cordwell, S.J. (2006) Technologies for bacterial surface proteomics. Current Opinion in Microbiology 9: 320-329. PubMedId: 16679049
  • White, M.Y., Hambly, B.D., Jeremy, R.W. and Cordwell, S.J. (2006) Ischemia-specific phosphorylation and myofilament translocation of Hsp27 precedes alpha B-crystallin and occurs independently of reactive oxygen species in rabbit myocardium. Journal of Molecular and Cellular Cardiology 40: 761-774. PubMedId: 16678850
  • White, M.Y., Tchen, A.S., McCarron, H.C.K., Hambly, B.D., Jeremy, R.W. and Cordwell, S.J. (2006) Proteomics of ischemia and reperfusion injuries in rabbit myocardium with and without intervention by an oxygen free radical scavenger. Proteomics 6: 6221-6233. PubMedId: 17133370
  • Jacobs, C., Ausmees, N., Cordwell, S.J., Shapiro, L. and Laub, M.T. (2003) The functions of the CckA histidine kinase in Caulobacter cell cycle control. Molecular Microbiology 47: 1279-1290. PubMedId: 12603734
  • Bae, S.-H., Harris, A.G., Chen, H., Hains, P.G., Garfin, D.E., Paik, Y.-K., Hazell, S.L., Walsh, B.J. and Cordwell, S.J. (2003) Characterization of highly basic proteins in proteome projects. Proteomics 3: 569-579. PubMedId: 12748937
  • Nouwens, A.S., Beatson, S.A., Whitchurch, C.B., Walsh, B.J., Schweizer, H.P., Mattick, J.S. and Cordwell, S.J. (2003) Proteome analysis of extracellular proteins regulated by the las and rhl quorum sensing systems in Pseudomonas aeruginosa. Microbiology 149:1311-1322. PubMedId: 12724392
  • Nouwens, A.S., Willcox, M.D.P., Walsh, B.J and Cordwell, S.J. (2002) Proteomic comparison of membrane and extracellular proteins from invasive (PA01) and cytotoxic (6206) strains of Pseudomonas aeruginosa. Proteomics 2: 1325-1346. PubMedId: 12362351
  • Cordwell, S.J., Larsen, M.R., Cole, R.T. and Walsh, B.J. (2002) Comparative proteomics of Staphylococcus aureus and the response of methicillin resistant and sensitive strains to Triton X-100. Microbiology 148: 2765-2781. PubMedId: 12213923
  • Cordwell, S.J., Wilkins, M.R., Cerpa-Poljak, A., Gooley, A.A., Duncan, M., Williams, K.L. and Humphery-Smith, I. (1995) Cross-species identification of proteins separated by two-dimensional gel electrophoresis using matrix-assisted laser desorption-ionisation / time-of-flight mass spectrometry and amino acid composition Electrophoresis 16: 438-443. PubMedId: 7607178