About Professor Iain McGregor

I have broad research interests in the areas of neuroscience and psychopharmacology. I am particularly interested in assessing the long term effects of addictive drugs and alcohol on behaviour and brain function. I am also interested in the development of animal models of anxiety disorders and depression and in the pharmacological treatment of these disorders.

Selected publications

Carson DS, Cornish JL, Guastella AJ, Hunt GE, and McGregor IS (in press) Oxytocin decreases methamphetamine self-administration, methamphetamine hyperactivity, and relapse to methamphetamine-seeking behaviour in rats. Neuropharmacology.

Hargreaves GA, Quinn H, Kashem MA, Matsumoto I, McGregor IS. (2009) Proteomic analysis demonstrates adolescent vulnerability to lasting hippocampal changes following chronic alcohol consumption. Alcoholism: Clinical and Experimental Research  33, 86-94.

Thompson MR, Hunt GE, McGregor IS. Neural correlates of MDMA ("Ecstasy")-induced social interaction in rats. Social Neuroscience 2009;4, 60-72.

Hargreaves, G.A., Monds, L., Gunasekaran, N., Dawson, b. and McGregor, I.S. (2009)  Intermittent access to beer promotes binge-like drinking in adolescent but not adult Wistar rats. Alcohol  in press.

Gunasekaran N, Long L, Arnold JC. McGregor IS. (in press) Reintoxication: the release of fat-stored delta-9-tetrahydrocannabinol (THC) into blood is enhanced by food deprivation or ACTH exposure. British Journal of Pharmacology.

Thompson M, Li KM, Clemens KC, Cornish JL, Hunt GE, McGregor IS (2004) Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA (“Ecstasy”) in rats. Neuropsychopharmacology, 29. 694-704.

Thompson, M.R., Callaghan, P.D., Hunt, G.E., Cornish, J.L. & McGregor IS (2007) A role for oxytocin and 5-HT1A receptors in the prosocial effects of MDMA. Neuroscience 146, 509-514.

J.L. Cornish, K.C. Clemens, M.R. Thompson, P.D. Callaghan, B Dawson and McGregor IS (2008) High ambient temperature increases intravenous methamphetamine self-administration in rats. Journal of Psychopharmacology, 22, 100-108.

McGregor, IS, Callaghan, PD, Hunt, GE. (2008) From ultrasocial to antisocial: a role for oxytocin in the acute reinforcing effects and long-term adverse consequences of drug use? British Journal of Pharmacology 2008;154, 358-368.

Quinn H.R., et al & McGregor IS (2008). Adolescent rats find repeated delta(9)-THC less aversive than adult rats but display greater residual cognitive deficits and changes in hippocampal protein expression following exposure. Neuropsychopharmacology. 33, 1113-1126.