SUCCESSFUL NHMRC Project GRANTS 2011

Faculty of Health Sciences

Chief investigator Other chief investigators School Project Total funding
Clemson, A/Prof Lindy Cameron, Prof Ian Lannin, Dr Natasha Rubenstein, Prof Laurence Gitlin, Prof Laura Health Sciences The HOME trial: Investigating the effectiveness of occupational therapy pre-discharge home visits and discharge planning for at-risk older people $985,313
Fiatarone Singh, Prof Maria  Brand-Miller, Prof Janette Vanwanseele, Dr Benedicte March, Prof Lyn Smith, A/Prof Richard Eckstein, Prof Felix Health Sciences Low GI Diet and High Intensity Resistance Training for Osteoarthritis of the Knee in Older Adults $572,734

Sydney Medical School

Chief investigator Other Chief Investigators School Project Total funding
Abendroth, Dr Allison Arvin, Prof Ann Slobedman, A/Prof Barry Central Clinical School The role of varicella zoster virus in modulating cutaneous infection $536,706
Alexander, Prof Ian Braet, A/Prof Filip Christodoulou, Prof John Kuchel, Prof Philip Carpenter, Dr Kevin Children's Hospital Westmead In vivo gene transfer and phenotype correction of normal and urea-cycle deficient primary human hepatocytes in chimeric mouse-human livers: Towards gene therapy for metabolic liver disease $476,706
Allan, Dr Charles Hadelsmann, Prof David Walters, Dr Kirsty Howell, Dr Viive Concord Clinical School FSH control of ovarian function $408,374
Bertolino, Dr Patrick Dwyer, Dr Karen Bowen, Dr David Bishop, Dr Alex Central Clinical School Deciphering mechanisms of liver allograft tolerance $502,983
Black, Prof Judy Burgess, Dr Janette Hansbro, A/Prof Philip School of Medical Sciences Fibulin-a target for lung fibrosis? $551,706
Black, Prof Judy Weckmann, Dr Markus Moir, Dr Lyn School of Medical Sciences Lamstatin- a novel inhibitor of lymphangiogenesis $636,732
Blair, Dr Ian Nicholson, Prof Garth Concord Clinical School Investigating the genetic basis of ALS $487,524
Booth, A/Prof David Ahlenstiel, Dr Golo Stewart, Prof Graeme George, Prof Jacob Western Clinical School The effect of IL28B haplotype on hepatitis C virus infection and treatment response $507,957
Brilot, Dr Fabienne Dale, Dr Russell Children's Hospital Westmead Autoimmune NMDAR encephalitis in children $481,996
Britton, Prof Warwick Triccas, Dr James Florido, Dr Manuela Stambas, Dr John Central Clinical School Impact of Influenza A infection on T cell-mediated immunity to pulmonary tuberculosis. $471,299
Bye, Prof Peter Bell, A/Prof Scott Elkins, Dr Mark Central Clinical School Novel Interventions for the Diverse Population of Australians with Bronchiectasis $439,208
Cass, Prof Alan Gallagher, Dr Martin Hillis, A/Prof Graham Brieger, A/Prof David Aylward, Prof Philip Chew, Prof Derek The George Institute for International Health The PRESERVE Trial: Prevention of Serious Adverse Events following angiography $2,323,394
Christie, Prof MacDonald Chieng, Dr Billy School of Medical Sciences The mechanisms responsible for tolerance at the mu-opioid receptor $543,390
Clarke, Prof Christine Graham, Dr Justine Western Clinical School Progesterone regulation of epithelial cell fate in the normal breast $538,549
Cook, Prof David Dinudom, A/Prof Anuwat School of Medical Sciences Regulation of epithelial sodium channels by caveolin $394,208
Cook, Prof David Dinudom, A/Prof Anuwat School of Medical Sciences Interaction between H5N1 and the respiratory epithelium $601,732
Fazekas De St Groth, Prof Barbara    Central Clinical School Mechanisms of islet graft rejection and acceptance $581,706
Fazekas De St Groth, Prof Barbara    Central Clinical School Control of allergic lung inflammation $459,615
Fazekas De St Groth, Prof Barbara  Shklovskaya, Dr Elena Central Clinical School Strategies to enhance CD4 T cell-mediated anti-tumour immunity $511,299
Fletcher, Prof John Wang, Dr Yiping Western Clinical School Redefining the role of macrophages in atherosclerosis: macrophage subset role in plaque stability $491,706
George, Prof Jacob Douglas, Dr Mark Western Clinical School Targeting the endocannabinoid system to treat chronic Hepatitis C $543,390
George, Prof Jacob  Wang, Dr Jianhua Western Clinical School The role of adiponectin-mediated nitric oxide on portal hypertension and liver fibrosis $508,390
George, Prof Jacob Hebbard, Dr Lionel Western Clinical School Role of adiponectin in hepatic carcinogenesis $361,072
Gilbert, Prof Gwendolyn Sintchenko, Dr Vitali O'Sullivan, Dr Matthew Iredell, A/Prof Jonathan Western Clinical School Microevolution and transmission of MRSA in a hospital setting $601,706
Gottlieb, Prof David   Faculty of Medicine /Western Clinical School Patient tailored immunity transplant for the prevention of viral infections post haemopoietic stem cell transplantation $548,364
Gotz, Prof Jurgen Ittner, Dr Lars School of Medical Sciences Selective vunerability in alzheimer's disease and related disorders: Mechanism of tau pathology $1,026,728
Haass, Dr Nikolas Weninger, Prof Wolfgang Central Clinical School Real-time Imaging of cell cycle progression in melanoma $466,299
Haber, Prof Paul Baillie, Dr Andrew Central Clinical School Exploring the efficacy of Baclofen in the treatment of alcoholic liver disease $638,836
Halliday, Prof Gary Lyons, Dr James Guy Central Clinical School Susceptibility of the basal layer of human epidermis to UVA oxidative damage due to pheomelanin and suboptimal DNA repair $540,048
Jamieson, Dr Robyn   Children's Hospital Westmead Genomic signposts, high-resolution sequencing and novel genes in eye disease $322,524
Jan, A/Prof Stephen Usherwood, Prof Timothy Brien, Prof Jo-anne Peiris, Dr David Rose, Dr John Hayman, A/Prof Noel Howard, Dr Kirsten School of Public Health What Determines Patients' Adherence to Treatment in Cardiovascular Disease Prevention? A Process Evaluation of The Kanyiniâ€"GAP Trial $247,524
Jolly, Dr Christopher   Central Clinical School Regulation of the quality of DNA repair by timing in the cell cycle $452,957
Korgaonkar, Dr Mayuresh Grieve, Dr Stuart Williams, Prof Leanne Western Clinical School Limbic maturational changes in adolescence and young adulthood (LIMCA) - A longitudinal study $404,615
Leeder, Prof Stephen Gillespie, Dr James Usherwood, Prof Timothy Boyages, Prof Steven School of Public Health The effect of a coordinated care intervention, Care Navigation, on the readmission rate of chronically ill patients at Nepean Hospital. $702,590
Lindley, Prof Richard Arima, Dr Hisatomi Parsons, A/Prof Mark Wang, Prof Jiguang Stapf, Dr Christian Western Clinical School INTERACT Expansion: Intensive Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial $2,117,787
Chan-Ling, Prof Tailoi   School of Medical Sciences Rationale for non-invasive treatment of Retinopathy of Prematurity: Dark Rearing as a means of mimicking physiological vascularisation $399,615
Little, David    Children's Hospital Westmead Novel therapeutic interventions for the orthopaedic complications of Neurofibromatosis type 1 (NF1) $606,732
Little, A/Prof David Schindeler, Dr Aaron Hamrick, Dr Mark Children's Hospital Westmead The role of muscle and the application of muscle-cell therapies in bone repair $423,786
Maher, Prof Chris Latimer, A/Prof Jane Koes, Prof Bart Blyth, Dr Fiona Ferreira, Dr Paulo The George Institute for International Health Triggers for low back pain $763,825
Marsh, A/Prof Deborah Baxter, Prof Robert Northern Clinical School Pyk2: a central mediator of gonadotropin action in ovarian cancer $322,524
Marshall, Dr Nathaniel Grunstein, Prof Ronald Wong, Dr Keith Yee, A/Prof Brendon Central Clinical School Modafinil for neurobehavioural dysfunction in sleep apnea patients who cannot use standard device-based treatments. $488,984
Mason, Prof Rebecca Conigrave, Prof Arthur School of Medical Sciences Novel strategies for the treatment of bone disease by nutrient activators of calcium-sensing receptors $212,091
McAvoy, Prof Johnston Lovicu, A/Prof Frank Central Clinical School Role of primary cilia and PCP proteins in lens development: implication for lens regeneration after cataract surgery $399,462
McLennan, A/Prof Susan Twigg, A/Prof Stephen Min, Dr Danqing Yue, Prof Dennis Central Clinical School Preventing Adverse Effects of Matrix Metalloproteinases in Diabetic Wound Healing $374,400
Melrose, Dr James Appleyard, Dr Richard Little, A/Prof Christopher Northern Clinical School Mesenchymal Progenitor cells and intervertebral disc repair $730,074
Morris, Prof Jonathan Roberts, A/Prof Christine Ford, Dr Jane Bowen, Dr Jennifer Buchanan, Dr Sarah Lain, Ms Samantha Northern Clinical School Immediate delivery vs expectant care in women with pre-term prelabour rupture of the membranes close to term- a randomised clinical trial (PPROMT) $832,930
Ng, Dr Martin Kars, Prof Richard Central Clinical School The Role of Androgens in Cardiovascular Repair and Regeneration $449,208
Ng, Dr Martin Wu, A/Prof Joseph Central Clinical School Defining the Cellular Basis for Therapeutic Angiogenesis: Characterisation of Endothelial Progenitor Cell Populations $352,524
Nicholson, Prof Garth Kennerson, Dr Marina Concord Clinical School Discovering Genes for X-linked Charcot-Marie-Tooth Neuropathy $471,273
North, Kathryn    Children's Hospital Westmead The influence of α-actinin-3 on muscle structure, metabolism, performance and response to diet and disease $556,871
O'Neill, A/Prof Christoper Li, Dr Yan Northern Clinical School Epigenetic reprograming after fertilization $419,208
O'Neill, A/Prof Christoper   Northern Clinical School Long term consequences of perturbing early embryo development $530,022
Osborne, Dr Peregrine Keast, A/Prof Janet Northern Clinical School Can persistent bladder pain be treated by targeting TRPA1 expressing nociceptors? $546,732
O'Toole, Dr Brian Catts, Prof Stanley Concord Clinical School Does PTSD in a parent increase the risk of mental health disorders in their offspring? $716,722
Patel, A/Prof Anushka Peiris, Dr David Usherwood, Prof Timothy Harris, Prof Mark Hayman, A/Prof Noel Panaretto, A/Prof Kathryn Redfern, Dr Julie Zwar, Prof Nick Colagiuri, Prof Stephen The George Institute for International Health Evaluation of a novel electronic decision support tool for cardiovascular risk management - the TORPEDO study $373,693
Pollock, Prof Carol Forbes, A/Prof Josephine Panchapakesan, Dr Usha Northern Clinical School Renal protection with SGLT2 inhibition $489,366
Reddel, Prof Roger Pickett, Dr Hilda Children's Medical Research Institute Telomere structural abnormalities in cells using alternative lengthening of teleomeres $504,615
Richardson, Des Suryo Rahmanto, Dr Yohan Ponka, Prof Prem School of Medical Sciences Development of Iron Complexes for the Treatment of Friedreichâ€TMs Ataxia & the Role of Frataxin in Iron Metabolism $595,048
Rinkwitz, Dr Silke Becker, Prof Thomas School of Medical Sciences Cis regulatory and functional analysis of genomic loci with implication in hypothalamic obesity using the zebrafish as a model system $465,022
Rizos, Dr Helen   Western Clinical School Dissecting PTEN-regulated pathways in the genesis of melanoma $292,524
Rizos, Dr Helen Kefford, Prof Richard Long, Dr Georgina Zhang, A/Prof Xu Dong Western Clinical School Manipulating the B-RAF/MEK pathway in the genesis and treatment of melanoma $543,390
Robinson, Prof Phillip McCluskey, Prof Adam Children's Medical Research Institute Sulfonadyn-based dynamin I-specific inhibitors and epilepsy $807,862
Rodgers, Prof Anthony Zoungas, Dr Sophia Harrap, Prof Stephen Colagiuri, Prof Stephen Matthews, Prof David Marre, Prof Michel The George Institute for International Health ADVANCE-ON: a post-trial observational study of ADVANCE $738,820
Siddall, Philip Henderson, Dr Luke Northern Clinical School Thalamic neuroplasticity and pain following spinal cord injury $289,182
Simanainen, Dr Ulla Handelsman, Prof David Concord Clinical School Intraprostatic androgen signalling as a target in prostate cancer $359,208
Slobedman, A/Prof Barry Mocarski, Prof Edward Abendroth, Dr Allison Western Clinical School Human cytomegalovirus encoded control of the latent phase of infection $616,315
Solomon, Dr Samuel Morley, Prof John School of Medical Sciences Nature and sensitivity of motion signals provided by neurons in the middle-temporal area of visual cortex $391,857
Steinbeck, Prof Katharine Hawke, Dr Catherine Hazell, Prof Philip Skinner, Dr Susan Rachel Ivers, A/Prof Rebecca Booy, Prof Robert Cumming, Prof Robert Fulcher, Prof Gregory Children's Hospital Westmead Adolescent Rural Cohort Study Hormones, Health, Education, Environments and Relationships $975,652
Stevenson, Dr Andrew Solomon, Prof Michael Hewett, Prof Peter Lumley, Dr John Fleshman, Prof Jim Clouston, A/Prof Andrew Hague, Dr Wendy School of Public Health A La CaRT: Australasian phase III randomised trial comparing laparoscopic-assisted versus open resection for rectal cancer $932,568
Tomlinson, Dr Susan Burke, Prof David Kiernan, Prof Matthew Central Clinical School The final common channel: measurement for nerve excitability $269,214
Truscott, Prof Roger Mitchell, Dr Todd Central Clinical School Ancient proteins and disease. $498,390
Vaughan, Dr Christopher Drew, Dr Geoffrey Northern Clinical School Endocannabinoid-TRP interactions in midbrain analgesic pathways $566,732
Venkatesh, Prof Bala Myburgh, Prof John Finfer, Prof Simon Webb, A/Prof Steven Cohen, Dr Jeremy The George Institute for International Health A randomised controlled trial of the effect of hydrocortisone on mortality in critically ill patients with septic shock $3,295,083
Welgampola, Dr Miriam Halmagyi, Prof Michael Zagami, A/Prof Alessandro Gibson, Prof William Carey, A/Prof John Todd, Mr Michael Central Clinical School Sound and Vibration-Evoked Vestibular Potentials in the Differential Diagnosis of Common Vestibulopathy $252,524
Welgampola, Dr Miriam Aw, Dr Swee Halmagyi, Prof Michael Central Clinical School Optimising the Diagnosis and Management of Benign Positioning Vertigo $277,524
Weninger, Prof Wolfgang   Central Clinical School Dynamics and mechanisms of neutrophil migration during tissue inflammation $511,299
West, Dr Nicholas Britton, Prof Warwick Payne, Dr Richard Central Clinical School Design, development and analysis of new tuberculosis drugs $702,165
Williams, Prof Leanne Harris, A/Prof Anthony Western Clinical School GEM study: General and Emotional Cognition in first onset psychosis $372,524

Faculty of Pharmacy

Chief investigator
Otherchief investigator
School
Project
Total funding
Bebawy, Dr Mary Grau, Prof Georges Combes, Dr Valery Pharmacy Microparticles and Selective Trait Dominance in Multidrug Resistant Cancers $396,273
Collins Chebib, A/Prof Mary Wellendorph, A/Prof Petrine McGregor, Prof Iain Hunt, Dr Glenn Bruner-Osborne, Prof Hans  Pharmacy Extrasynaptic GABA-A receptors as novel targets for γ-Hydroxybutyric acid (GHB) $508,136
Gelissen, Dr Ingrid Brown, A/Prof Andrew Pharmacy Control of expression and activity of the ABCG1 cholesterol transporter in vascular cells $376,273

Faculty of Science

Chief investigator
Other chief investigators
School
Project
Total funding
Campbell, Prof Iain   Molecular and Microbial Biosciences Role of IRF8 in central nervous system glial cell function $414,615
Conigrave, Prof Arthur Ward, Dr Donald Molecular and Microbial Biosciences A solution to the parathyroid gland secretion problem $490,470
Mackay, Prof Joel Blobel, Prof Gerd Molecular and Microbial Biosciences Structural and functional analysis of a cancer-linked co-regulator complex $536,706
Matthews, A/Prof Jacqueline  Mackay, Prof Joel Guss, Prof Jules Molecular and Microbial Biosciences LMO2-containing complexes in leukemia and blood cell development $775,914
Nicholas, Dr Hannah Crossley, Prof Merlin Molecular and Microbial Biosciences Identifying regulators of the DNA damage response and tumorigenesis using C. elegans $496,706
Simpson, Prof Stephen Conigrave, Prof Arthur Biological Sciences Interactions between protein leverage, variety, and dietary carbohydrate and fat content in the control of energy intake in humans $562,540
Szabo, Dr Marianna Lovibond, Prof Peter Psychology The structure of negative affective states in youth: Identifying the specific symptoms of depression, anxiety and tension/stress in children and adolescents $232,524