NHMRC Project Grants commencing in 2014

Chief Investigator Faculty Project Amount
Allison Abendroth Sydney Medical School Defining key mechanisms that underpin neuropathogenesis of varicella zoster virus during herpes zoster $596,226
Christina  Adler Faculty of Dentistry Determining how genetic and environmental factors influence the developing oral microbiota and drive disease in early childhood


Ian Alexander Sydney Medical School Reconstitution of B-cell ontogeny in Btk-deficient patient-derived CD34+ cells in a humanised mouse model: The foundations for an Australian XLA gene therapy trial


Ian Alexander Sydney Medical School Development of a novel hybrid rAAV/transposon gene delivery system for life-long correction of metabolic liver disease in infants and children


Hisatomi Arima Sydney Medical School Head Position in Stroke Trial (HeadPoST)


Thomas Balle Pharmacy New positive allosteric modulators of nicotinic acetylcholine receptors for treatment of cognitive impairment in ADHD


Janette Burgess Sydney Medical School The central role of Connective Tissue Growth Factor in remodelling of asthmatic airways


Steven Chadban Sydney Medical School Targeting Innate Immunity Through Hmgb1 To Prevent Diabetic Nephropathy


Hak-Kim (Kim) Chan Pharmacy Novel inhalation formulation of colistin and combination therapy against Gram-negative 'superbugs'


Roderick Clifton-Bligh Sydney Medical School Transcription Factor Foxe1 And Thyroid Cancer


Rachel Codd Sydney Medical School Lipophilic iron chelators as potential therapeutic agents in Parkinson's disease


Mary Collins (Chebib) Pharmacy γ-Hydroxybutyric acid (GHB) and α4-containing GABA-A receptors


Tamera Jo Corte Sydney Medical School Novel Methods for the Early Identification of Progressive Disease in Idiopathic Pulmonary Fibrosis


Robert Cumming Sydney Medical School Study of the relationship of oral health and oral health service utilisation to the general health of older Australian men


Anthony (Tony) Cunningham Sydney Medical School The mechanism of HSV-1 transport in sensory axons and its unique assembly at the axon terminus


Andrew Davidson Sydney Medical School NITRO Trial: A randomised phase III trial of adding nitroglycerin to first line chemotherapy for advanced non-small cell lung cancer


Michael Dibley Sydney Medical School Long term impact of a community-based cluster randomized controlled trial of peer counselling to improve infant feeding on growth & cognitive function of children up to 5 years in urban Bangladesh


Julianne Djordjevic Sydney Medical School Signalling pathways and fungal virulence - the inositol polyphosphate biosynthetic pathway in Cryptococcus neoformans


Michael Friedlander Sydney Medical School Does Palliative Chemotherapy Palliate? Measuring symptom benefit in recurrent ovarian cancer using patient reported outcomes: The Symptom Benefit Study


David Gottlieb Sydney Medical School A clinical trial of partially HLA-matched unrelated donor microtransplantation for prevention of relapse in patients with acute myeloid leukaemia ineligible for standard haemopoietic stem cell transplantation


Maree Hackett Sydney Medical School The validation of a culturally-specific measure to identify depression in Aboriginal and Torres Strait Islander people with or without chronic disease


David Harris Sydney Medical School Defining the role of the major subsets of renal mononuclear phogocytes


Luke Henderson Sydney Medical School Does a pain-specific pathway exist in humans?


Luke Henderson Sydney Medical School Underlying mechanims of thalamocortical dysrhythmia in chronic pain


Ian Hickie Sydney Medical School Clinical and neurobiological predictors of onset of major mental disorders (mania, psychosis, severe depression), and associated functional impairment, in adolescent and young adult twins: A prospective longitudinal study


Edward Holmes Faculty of Science Black Death genomics and the evolution of pathogen virulence


David Hunter Sydney Medical School Randomized controlled trial of hip arthroscopy for femoroacetabular impingement


Jodie Ingles Sydney Medical School Clinical, Genetic and Psychosocial Aspects of Sudden Cardiac Death


Rebecca Ivers Sydney Medical School Understanding burn injuries in Aboriginal and Torres Strait Islander children: treatment, access to services and outcomes.


Alicia Jenkins Sydney Medical School Fenofibrate And Microvascular Events in Type 1 Diabetes (FAME 1) Trial


Christopher Jolly Sydney Medical School Cell cycle tracking of B cell differentiation and mutation


Angela Laird Sydney Medical School Investigating drug treatments for a Machado Joseph disease using transgenic zebrafish


Simon Lewis Sydney Medical School Understanding and predicting freezing of gait in Parkinson's Disease.


Helen Liley Sydney Medical School Preventing Adverse Outcomes of Neonatal Hypoxic Ischaemic Encephalopathy with Erythropoietin: A Randomised Controlled Multicentre Australian Trial


Nicholas Lintzeris Sydney Medical School Randomised control trial of exercise for the management of cannabis withdrawal in adult humans


Wendy Lipworth Sydney Medical School Conflicts of interest in public health and biomedicine: enhancing professional integrity and safeguarding the public's health


Joel Mackay Faculty of Science Do transcription factor-RNA interactions represent a new mechanism of gene regulation?


Joel Mackay Faculty of Science Structural and functional analysis of a cancer-linked co-regulator complex


Rebecca Mason Sydney Medical School Is CYP11A1 critical for the vitamin D photoprotective system in skin?


Kirsten McCaffery Sydney Medical School Informing women about over-diagnosis in mammography screening: a randomised trial


Jonathan Morris Sydney Medical School Working towards a new therapy for the prevention of restricted fetal growth


Sharon Naismith Sydney Medical School A selective prevention trial using novel pharmacotherapies in an older age cohort at risk for depression


Matthew Naylor Sydney Medical School A novel role for CBF(B) as a regulator of breast cancer


Martin Ng Sydney Medical School Bioengineering Synthetic Elastin Conduits for Arterial Revascularisation


Martin Ng Sydney Medical School The protective effects of fenofibrate in diabetes-related susceptibility to ischaemia


Christopher O'Neill Sydney Medical School Epigenetic reprogramming within the pluripotent lineage of the early embryo


Matthew O'Sullivan Sydney Medical School The true burden of nosocomial staphylococcal disease: Genomic markers of transmission of methicillin-sensitive and - resistant Staphylococcus aureus


Sarah Palmer Sydney Medical School Characterising latent HIV reservoirs: examining the effects of treatment initiation, cellular type and patient genetics.


Richard Payne Faculty of Science Development of Antimalarial Drug Leads Through Inhibition of Food Vacuole Falcipains


Paul Pilowsky Sydney Medical School PACAP, sleep apnoea and high blood pressure


John Rasko Sydney Medical School Intron retention regulation in granulopoiesis and leukaemia


Roger Reddel Sydney Medical School Activation of TERT gene expression in breast carcinogenesis


Desi (Des) Richardson Sydney Medical School Pharmacological Targeting of Integrated Oncogenic and Tumour Suppressive Pathways using Novel Therapeutics


Desi (Des) Richardson Sydney Medical School The Physiological Role of Glutathione-S-Transferase in the Intracellular Storage and Transport of Nitric Oxide and its Biomedical Effects


Helen Rizos Sydney Medical School Melanoma resistance to combination BRAF and MEK inhibition is driven by reprogramming of MAPK signaling


Nicholas Shackel Sydney Medical School The Role of the Hepatocyte and EMMPRIN in Liver Injury


Catherine Sherrington Sydney Medical School Does feedback from affordable technology enhance physical activity levels and mobility outcomes in neurological and aged care rehabilitation: an RCT


Barry Slobedman Sydney Medical School How does human cytomegalovirus control host responses to infection to facilitate human disease?


Patrick Tam Sydney Medical School Aberrant mesenchymal-epithelial transition: a pathogenic mechanism in tissue maintenance and differentiation


William Tarnow-Mordi Sydney Medical School Should we treat iron deficiency anaemia of pregnancy with lactoferrin? A randomised controlled trial


Cindy Thamrin Sydney Medical School Prediction of clinical outcomes in COPD from home monitoring of lung function variability


Lyndal Trevena Sydney Medical School Should I take low dose aspirin? The 'Optimise' decision aid study


Yiping Wang Sydney Medical School Therapeutic potential of peritoneal mononuclear phagocytes from peritoneal dialysis patients


Miriam Welgampola Sydney Medical School Optimising balance function in vestibular schwannoma


Wolfgang Weninger Sydney Medical School The role of perivascular macrophages in the regulation of skin inflammation


Xianjiang Zheng Sydney Medical School The role of Heg-CCM2L signaling in angiogenesis