Inhaled irritants can stimulate some cells to begin abnormal growth. This cancerous growth can be an indurating (hardened) or ulcerating mass within the bronchial lumen or wall.Smoking is a common cause of lung cancer.
Cancerous Lung Tissue
Many irritants have been implicated in the aetiology of lung cancer but the most important of these is cigarette smoke, which contains at least 43 carcinogens. The risk of developing lung cancer and mortality increases with duration and intensity of exposure.