Overview of NMR
The NMR Facility provides a range of flexible services which can be adapted to best suite the needs of your applications. Services provided by the NMR Facility include:
- Sample Analysis Service. Samples can be sent to us for analysis by NMR Spectroscopy. This service is not limited to School of Chemistry researchers, and we welcome enquires from all disciplines within the University, and the wider community. You can read more on the Analysis Service Page
- Training and Education. Staff of the NMR Facility provide training to NMR users in spectrometer operation and software applications. Training seminars are held periodically throughout the year covering a range of topics aimed at introductory and intermediate level. Please speak to Dr Ian Luck for more information about training and education assistance.
- Consultation and Technical Assistance. We are able to provide consultation and assistance in experimental design, data processing and interpretation for your NMR experiments. Staff have expertise in a wide range of chemical applications, with particular interests in organic, organometallic, bioorganic and phosphorus chemistry.
School of Chemistry NMR users
The NMR Facility offers support for your research and analytical projects through a number of avenues:
- Training to operate NMR spectrometers and software
- Consultation and advice in experimental choice and design
- Collaboration in NMR oriented research projects
- Assistance in data processing and interpretation
The NMR Facility encourages all Chemistry School users of NMR to broaden their knowledge of NMR and gain plenty of hands-on experience using a wide range of experimental techniques and different equipment. All users must be licensed prior to using the spectrometers and for those new to NMR, training sessions are available. For details about training, licensing and other services available to internal users, please visit the internal NMR Facility website, nmrnet.
Instructions for sample submissions
Samples being sent from outside the School of Chemistry should be addressed to:
School of Chemistry, F11
The University of Sydney NSW 2006
All samples submitted to the NMR Facility Analysis Service should be appropriately packaged and accompanied by a sample submission form. Each sample submitted should have a unique sample code. Please try to fill out all sections of the form, taking care to ensure that sample code information on the sample container matches that supplied on the submission form. Samples must be fully soluble in the nominated solvent for analysis to be possible. Please speak to NMR Staff if you have doubts about the solubility or correct choice of solvent for your samples.
School of Chemistry submissions
Samples should be brought to the NMR Facility Office with the correctly filled forms. All samples must be appropriately stored and labelled. Sample containers that have inadequate labelling or are inappropriately stored will not be handled by NMR staff.
For each sample submitted, fill out one copy of the NMR Facility Analysis Service: Sample Submission Form.
Sample types and amounts
The NMR spectrometers of the NMR Facility are all solution-state spectrometers, which means that, in most cases, only solutions can be analysed. Liquid or solid samples must be dissolved in a small amount of deuterated solvent, therefore it is important that a solvent providing suitable solubility can be nominated. Common (deuterated) solvents that are available include chloroform, water, methanol, acetone, dimethyl sulfoxide and acetonitrile. Other solvents are available.
Experiments can be carried out on as little as 5 milligrams of sample (in some cases, even less), however it is usually beneficial for data collection and cost effectiveness to provide 50-100 milligrams of sample. Most NMR techniques are non-destructive, so samples can be returned to the client if requested. Throughput of samples will depend on the type of experiments required, as well as the amount of sample provided. Where sample quantity is not limited, routine analysis of samples by NMR offers an extremely cost efficient method of testing.