Our research is focused on applying the tools of organic chemistry to
probe problems of medicinal and biological significance. Projects are
multidisciplinary in nature, and involve the use of computer-aided drug
discovery, solution- and solid-phase organic synthesis, compound screening
technologies and crystallography.
Research programmes that we are currently pursuing in the group
- Design, synthesis and biological evaluation of enzyme inhibitors as
new antibacterial and anti-parasitic drug leads.
- Synthesis of neuraminidase inhibitors as new influenza, avian
influenza (bird flu) and equine influenza (horse flu) anti-virals.
- Synthesis of glycopeptide-based cancer vaccine candidates.
- Development of new methods for the synthesis of therapeutic
glycopeptides and glycoproteins.