Protein structure, function and engineering lab Publications from Prof. Jacqui Matthews

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Refereed journal articles
  1. Wilkinson-White, L. and Matthews, J.M. (2014)
    The PA207 peptide inhibitor of LIM-only protein 2 (Lmo2) targets zinc finger domains in a non-specific manner.
    Prot Prot Lett 21, 132-9.

  2. Youngson, N., Epp, T., Roberts, A., Daxinger, L., Ashe, A., Huang, E., Lester, K.L., Harten, S., Kay, G., Cox, T., Matthews, J.M., Chong, S., and Whitelaw, E. (2013)
    No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations
    Mamm Genome 24, 206-217.

  3. Vandevenne, M., Jacques, D.A., Arzur, C., Nguyen, C.D., Matthews, J.M., Crossley, M., Guss, J.M., and Mackay, J.P. (2013)
    New insights into DNA recognition by zinc fingers revealed by structural analysis of ZNF217
    J Biol Chem 288, 10616-10627.

  4. Stokes, P.H., Liew, C.W., Kwan, A.H., Foo, P., Barker, H.E., Djamirze, A., O'Reilly, V., Visvader, J.E., Mackay, J.P., and Matthews, J.M. (2013)
    Structural basis of the interaction of the breast cancer oncogene LMO4 with the tumour suppressor CtIP/RBBP8
    J Mol Biol 425, 1101-1110.

  5. Matthews, J.M. and Potts, J.R. (2013)
    The tandem β-zipper: modular binding of tandem domains and linear motifs
    FEBS Lett 587, 1164-1171.

  6. Matthews, J.M., Lester, K.L., Joseph, S., and Curtis, D.J. (2013)
    LIM-domain-only proteins in cancer
    Nat Rev Cancer 12, 111-122.

  7. Joseph, J., Kwan, A.H.Y., Mackay, J.P., Cubeddu, L., and Matthews, J.M. (2013)
    Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1
    Biol NMR Assign Feb 16 [EPub ahead of print].

  8. Gamsjaeger, R., O'Connell, M.R., Cubeddu, L., Shepherd, N.E., Lowry, J.A., Kwan, A.H., Vandevenne, M., Swanton, M.K., Matthews, J.M., and Mackay, J.P. (2013)
    A structural analysis of DNA binding by Myelin Transcription Factor 1 double zinc fingers
    J Biol Chem 28, 35180-91.

  9. Gamsjaeger, R., Fernando, R., Bang, L.H., Touma, C., Nguyen, C.D., Matthews, J.M., Cubeddu, L., and Mackay, J.P. (2013)
    Semi-quantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in Surface Plasmon Resonance competition experiments
    Anal. Biochem. 440, 178-185.

  10. Gadd, M.S., Jacques, D.A., Nisevic, I., Craig, V.J., Kwan, A.H., Guss, J.M., and Matthews, J.M. (2013)
    A structural basis for the regulation of the LIM-homeodomain protein Islet 1 (Isl1) by intra- and intermolecular interactions
    J Biol Chem 288, 21924-35.

  11. Corciliusa, L., Santhakumar, G., Stone, R.S., Capicciotti, C.J., Joseph, J., Matthews, J.M., Ben, R.N., and Payne, R.J. (2013)
    Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules
    Bioorganic Med Chem 21, 3569-3581.

  12. Campbell, A.E., Wilkinson-White, L., Mackay, J.P., Matthews, J.M., and Blobel, G.A. (2013)
    Dissecting molecular pathways that underlie disease-causing GATA1 mutations
    Blood 121, 5218-5227.

  13. Yeo, G., Baldock, C., Tuukkanenc, A., Roesslec, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., and Weiss, A. (2012)
    The tropoelastin bridge region positions the cell-interactive C-terminus and contributes to elastic fiber assembly
    Proc Natl Acad Sci U S A 109, 2878-83.

  14. Wilkinson, B.L., Stone, R.S., Capicciotti, C.J., Thaysen-Andersen, M., Matthews, J.M., Packer, N.H., Ben, R.N., and Payne, R.J. (2012)
    Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins
    Angew Chem 51, 3606-10.

  15. O'Connell, M.R., Vandevenne, M., Nguyen, C.D., Matthews, J.M., Gamsjaeger, R., Segal, D.J., and Mackay, J.P. (2012)
    Modular assembly of RanBP2-type zinc finger domains to target single-stranded RNA
    Angew Chem 51, 5371-5.

  16. Matthews, J.M. and Sunde, M. (2012)
    Dimers, oligomers, everywhere
    Adv Exp Med Biol 747, 1-18.

  17. Liew, C.W., Kwan, A.H., Stokes, P.H., Mackay, J.P., and Matthews, J.M. (2012)
    (1)H, (1)(5)N and (1)(3)C assignments of an intramolecular LMO4-LIM1/CtIP complex
    Biomol NMR assign 6, 31-4.

  18. Hsieh, Y.S., Wilkinson, B.L., O'Connell, M.R., Mackay, J.P., Matthews, J.M., and Payne, R.J. (2012)
    Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants
    Org Lett 14, 1910-3.

  19. Hauswirth, R., Haase, B., Blatter, M., Brooks, S.A., Burger, D., Drogemuller, C., Gerber, V., Henke, D., Janda, J., Jude, R., Magdesian, K.G., Matthews, J.M., Poncet, P.A., Svansson, V., Tozaki, T., Wilkinson-White, L., Penedo, M.C., Rieder, S., and Leeb, T. (2012)
    Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses
    PloS Genet 8, e1002653.

  20. Gadd, M.S., Jacques, D.A., Guss, J.M., and Matthews, J.M. (2012)
    Crystallization and diffraction of an Isl1-Ldb1 complex
    Acta Crystallogr Section F 68, 1398-401.

  21. Dastmalchi, S., Wilkinson-White, L., Kwan, A.H., Gamsjaeger, R., Mackay, J.P., and Matthews, J.M. (2012)
    Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex
    Prot Sci 6, 31-4.

  22. Cubeddu, L., Joseph, S., Richard, D.J., and Matthews, J.M. (2012)
    Contribution of DEAF1 structural domains to the interaction with the breast cancer oncogene LMO4
    PloS One 7, e39218.

  23. Bhati, M., Lee, C., Gadd, M.S., Jeffries, C.M., Kwan, A., Whitten, A.E., Trewhella, J., Mackay, J.P., and Matthews, J.M. (2012)
    Solution Structure of the LIM-Homeodomain Transcription Factor Complex Lhx3/Ldb1 and the Effects of a Pituitary Mutation on Key Lhx3 Interactions
    PloS One 7, e40719.

  24. Wissmueller, S., Font, J., Liew, C.W., Cram, E., Schroeder, T., Turner, J., Crossley, M., Mackay, J.P., and Matthews, J.M. (2011)
    Protein-protein interactions: analysis of a false positive GST pulldown result.
    Proteins Struct Funct Gen 79, 2365-71.

  25. Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P.H., Crossley, M., Mackay, J.P., and Matthews, J.M. (2011)
    Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1
    Proc Natl Acad Sci U S A 108, 14443-8.

  26. Gadd, M.S., Bhati, M., Jeffries, C.M., Langley, D.B., Trewhella, J., Guss, J.M., and Matthews, J.M. (2011)
    The structural basis for partial redundancy in a class of transcription factors, the LIM homeodomain proteins, in neural cell type specification
    J Biol Chem 42971-80.

  27. Wilkinson-White, L.E., Dastmalchi, S., Kwan, A.H., Ryan, D.P., Mackay, J.P., and Matthews, J.M. (2010)
    (1)H, (15)N and (13)C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex
    Biomol NMR Assign.

  28. Cross, A.J., Jeffries, C.M., Trewhella, J., and Matthews, J.M. (2010)
    LIM domain binding proteins one and two have different oligomeric states
    J Mol Biol 99, 133-44.

  29. Matthews, J.M., Bhati, M., Lehtomaki, E., Mansfield, R.E., Cubeddu, L., and Mackay, J.P. (2009)
    It takes two to tango: the structure and function of LIM, RING, PHD and MYND domains
    Curr Pharm Des 15, 3681-96.

  30. Lowther, J., Robinson, M.W., Donnelly, S.M., Xu, W., Stack, C.M., Matthews, J.M., and Dalton, J.P. (2009)
    The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease
    PLoS Negl Trop Dis 3, e369.

  31. Lowry, J.A., Gamsjaeger, R., Thong, S.Y., Hung, W., Kwan, A.H., Broitman-Maduro, G., Matthews, J.M., Maduro, M., and Mackay, J.P. (2009)
    Structural analysis of med-1 reveals unexpected diversity in the mechanism of DNA recognition by gata-type zinc finger domains
    J Biol Chem 284, 5827-5835.

  32. Gadd, M.S., Langley, D.B., Guss, J.M., and Matthews, J.M. (2009)
    Crystallization and diffraction of an Lhx4-Isl2 complex
    Acta Crystallogr Sect F Struct Biol Cryst Commun 65, 151-3.

  33. Ryan, D.P., Duncan, J.L., Lee, C., Kuchel, P.W., and Matthews, J.M. (2008)
    Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12
    Proteins 70, 1461-74.

  34. Pilotelle-Bunner, A., Matthews, J.M., Cornelius, F., Apell, H.J., Sebban, P., and Clarke, R.J. (2008)
    ATP Binding Equilibria of the Na(+),K(+)-ATPase (dagger)
    Biochemistry 47, 13103-13114.

  35. Matthews, J.M., Loughlin, F.E., and Mackay, J.P. (2008)
    Designed metal-binding sites in biomolecular and bioinorganic interactions
    Curr Opin Struct Biol 18, 484-90.

  36. Matthews, J.M., Bhati, M., Craig, V.J., Deane, J.E., Jeffries, C., Lee, C., Nancarrow, A.L., Ryan, D.P., and Sunde, M. (2008)
    Competition between LIM-binding domains
    Biochem Soc Trans 36, 1393-7.

  37. Mackay, J.P., Sunde, M., Lowry, J.A., Crossley, M., and Matthews, J.M. (2008)
    Response to Chatr-aryamontri et al.: Protein interactions: to believe or not to believe?
    Trends Biochem Sci

  38. Gamsjaeger, R., Swanton, M.K., Kobus, F.J., Lehtomaki, E., Lowry, J.A., Kwan, A.H., Matthews, J.M., and Mackay, J.P. (2008)
    Structural and biophysical analysis of the DNA binding properties of myelin transcription factor 1
    J Biol Chem 283, 5158-67.

  39. Bhati, M., Lee, M., Nancarrow, A.L., Bach, I., Guss, J.M., and Matthews, J.M. (2008)
    Crystallization of an Lhx3-Isl1 complex
    Acta Crystallogr Sect F Struct Biol Cryst Commun 64, 297-9.

  40. Bhati, M., Lee, C., Nancarrow, A.L., Lee, M., Craig, V.J., Bach, I., Guss, J.M., Mackay, J.P., and Matthews, J.M. (2008)
    Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes
    EMBO J 27, 2018-29.

  41. Stokes, P.H., Thompson, L.S., Marianayagam, N.J., and Matthews, J.M. (2007)
    Dimerization of CtIP may stabilize in vivo interactions with the Retinoblastoma-pocket domain
    Biochem Biophys Res Commun 354, 197-202.

  42. Porter, C.J., Matthews, J.M., Mackay, J.P., Pursglove, S.E., Schmidberger, J.W., Leedman, P.J., Pero, S.C., Krag, D.N., Wilce, M.C., and Wilce, J.A. (2007)
    Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation
    BMC Struct Biol 7, 58.

  43. Mackay, J.P., Sunde, M., Lowry, J.A., Crossley, M., and Matthews, J.M. (2007)
    Protein interactions: is seeing believing?
    Trends Biochem Sci 32, 530-1.

  44. Chong, S., Vickaryous, N., Ashe, A., Zamudio, N., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J., Scott, H.S., de Kretser, D., O'Bryan, M., Blewitt, M., and Whitelaw, E. (2007)
    Modifiers of epigenetic reprogramming show paternal effects in the mouse
    Nat Genet 39, 614-622.

  45. Ryan, D.P., Sunde, M., Kwan, A.H.-Y., Marianayagam, N.J., Nancarrow, A.L., vanden Hoven, R.N., Thompson, L.S., Baca, M., Mackay, J.P., Visvader, J.E., and Matthews, J.M. (2006)
    Identification of the key LMO2-binding determinants on Ldb1
    J. Mol. Biol. 359, 66-75.

  46. Kwan, A.H., Winefield, R.N., Sunde, M., Matthews, J.M., Haverkamp, R.G., Templeton, M.D., and Mackay, J.P. (2006)
    Structural basis for rodlet assembly in hydrophobins
    Proc. Natl Acad. Sci. USA 103, 3621-6.

  47. Jeffries, C., Graham, S., Stokes, P.H., Collyer, C.A., Guss, J.M., and Matthews, J.M. (2006)
    Stabilization of a binary protein complex through intein-mediated circularization.
    Protein Science 15, 2612-8.

  48. Ely, L.K., Beddoe, T., Clements, C.S., Matthews, J.M., Purcell, A.W., Kjer-Nielsen, L., McCluskey, J., and Rossjohn, J. (2006)
    Disparate thermodynamics governing TcR-pMHCI interactions implicate extrinsic factors in guiding MHC restriction
    Proc. Natl. Acad. Sci. USA 103, 6641-6.

  49. Begg, G.E., Holman, S.R., Stokes, P.H., Matthews, J.M., Graham, R.M., and Iismaa, S.E. (2006)
    Mutation of a critical GTP-binding arginine in transglutaminase 2 disinhibits crosslinking activity invitro and in vivo
    J. Biol. Chem. 281, 12603-9.

  50. Begg, G.E., Carrington, L., Stokes, P.H., Matthews, J.M., Wouters, M.A., Husain, A., Lorand, L., Iismaa, S.E., and Graham, R.M. (2006)
    Mechanism of allosteric inhibition of transglutaminase 2
    Proc. Natl Acad. Sci. USA 103, 19683-8.

  51. Williams, N., Liepinsh, E., Prosselkov, P., Watt, S.J., Matthews, J.M., Attard, P., Beck, J.L., Dixon, N.E., and Otting, G. (2005)
    Stabilization of Native Protein Fold by Intein-Mediated Covalent Cyclization
    J. Mol. Biol. 346, 1095-108.

  52. Sharpe, B.K., Liew, C.K., Kwan, A.H., Wilce, J.A., Crossley, M., Matthews, J.M., and Mackay, J.P. (2005)
    Assessment of the robustness of a serendipitous zinc-binding fold: mutagenesis and protein grafting
    Structure 13, 257-66.

  53. Ryan, D.P. and Matthews, J.M. (2005)
    Protein:Protein Interactions in Human Disease
    Curr Opin Struct Biol 15, 441-446.

  54. Liew, C.K., Simpson, R.J.Y., Kwan, A.H., Crofts, L.A., Loughlin, F.E., Matthews, J.M., Crossley, M., and Mackay, J.P. (2005)
    Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction.
    Proc Natl Acad Sci USA 102, 583-8.

  55. Lee, C., Nancarrow, A.L., Bach, I., Mackay, J.P., and Matthews, J.M. (2005)
    Letter to the Editor: 1H, 15N and 13C assignments of an intramolecular Lhx3:ldb1 complex
    J. Biomol. NMR 33, 198.

  56. Duggin, I.G., Matthews, J.M., Wake, G., Dixon, N.E., and Mackay, J.P. (2005)
    A Complex mechanism Controls Polarity of DNA Replication Fork Arrest by the Replication Terminator Complex of Bacillus subtilis
    J. Biol. Chem. 280, 13105-13113.

  57. Westman, B.J., Perdomo, J., Matthews, J.M., Crossley, M., and Mackay, J.P. (2004)
    Structural studies on a protein-binding zinc-finger domain of Eos reveal both similarities and differences to classical zinc fingers
    Biochemistry 43, 13318-27.

  58. Sunde, M., McGrath, K.C., Young, L., Matthews, J.M., Chua, E.L., Mackay, J.P., and Death, A.K. (2004)
    TC-1 is a novel tumorigenic and natively disordered protein associated with thyroid cancer
    Cancer Res. 64, 2766-73.

  59. Simpson, R.J., Lee, S.H., Bartle, N., Sum, E.Y., Visvader, J.E., Matthews, J.M., Mackay, J.P., and Crossley, M. (2004)
    A classical zinc finger from FOG mediates an interaction with the coiled-coil of TACC3
    J. Biol. Chem. 279, 39789-39797.

  60. Marianayagam, N.J., Sunde, M., and Matthews, J.M. (2004)
    The power of two:protein dimerization in biology
    Trends Biochem. Sci. 29, 618-25.

  61. Dubin, M.J., Stokes, P.H., Sum, E.Y.H., Williams, R.S., Valova, V.A., Robinson, P.J., Lindeman, G.J., Glover, J.N.M., Visvader, J.E., and Matthews, J.M. (2004)
    Dimerization of a BRCA1- and CtBP-interacting protein is mediated by an N-terminal coiled-coil motif.
    J. Biol. Chem. 279, 26932-8.

  62. Deane, J.E., Ryan, D.P., Sunde, M., Maher, M.J., Guss, J.M., Visvader, J.E., and Matthews, J.M. (2004)
    Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex
    EMBO J. 23, 3589-98.

  63. Turner, J., Nicholas, H., Bishop, D., Matthews, J.M., and Crossley, M. (2003)
    The LIM protein FHL3 is a Basic Krüppel-like Factor (BKLF) co-repressor, and forms a three-way nuclear specific complex with BKLF and mCtBP2
    J. Biol. Chem. 278, 12786-12795.

  64. Simpson, R., Cram, E., Czjoli, R., Matthews, J.M., Crossley, M., and Mackay, J.P. (2003)
    CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions
    J. Biol. Chem. 278, 28011-8.

  65. Matthews, J.M. and Visvader, J.E. (2003)
    LIM domain binding protein 1 (Ldb1): a multifunctional cofactor that interacts with diverse proteins
    EMBO Reports 1132-1137.

  66. Kwan, A.H., Gell, D.A., Verger, A., Crossley, M., Matthews, J.M., and Mackay, J.P. (2003)
    Engineering a protein scaffold from a PHD finger
    Structure 11, 803-13.

  67. Deane, J.E., Maher, M.J., Langley, D., Graham, S., Visvader, J.E., Guss, J.M., and Matthews, J.M. (2003)
    Crystallization of FLINC4, an intra-molecular LMO4:ldb1 complex
    Acta Crystallog D 59, 1484-1486.

  68. Deane, J.E., Mackay, J.P., Kwan, A.H., Sum, E.Y., Visvader, J.E., and Matthews, J.M. (2003)
    Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4
    EMBO J 22, 2224-2233.

  69. Warton, K., Tonini, R., Fairlie, W.D., Matthews, J.M., Valenzuela, S.M., Qiu, M.R., Wu, W.M., Pankhurst, S., Bauskin, A.R., Harrop, S.J., Campbell, T.J., Curmi, P.M.G., Breit, S.N., and Mazzanti, M. (2002)
    Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in CHO cells expressing CLIC1.
    J. Biol. Chem. 277, 26003-11.

  70. Sharpe, B.S., Matthews, J.M., Kwan, A.H.-Y., Newton, A., Gell, D.A., Crossley, M., and Mackay, J.P. (2002)
    A new zinc-binding fold underlines the versatility of zinc-binding modules in evolution
    Structure 10, 639-48.

  71. Matthews, J.M. and Sunde, M. (2002)
    Zinc fingers--folds for many occasions
    IUBMB Life 54, 351-5.

  72. Kowalski, K., Liew, C.K., Matthews, J.M., Gell, D.A., Crossley, M., and Mackay, J.P. (2002)
    Characterization of the conserved interface between GATA- and FOG-family proteins
    J. Biol. Chem. 277, 35720-9.

  73. Deane, J.E., Visvader, J.E., Mackay, J.P., and Matthews, J.M. (2002)
    1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex
    J. Biomol. NMR 23, 165-6.

  74. Matthews, J.M., Visvader, J.E., and Mackay, J.P. (2001)
    1H, 15N and 13C assignments of FLIN2, an intramolecular LMO2:ldb1 complex
    J Biomol NMR 21, 385-386.

  75. Mackay, J.P., Matthews, J.M., Winefield, R.D., Mackay, L.G., Haverkamp, R.G., and Templeton, M.D. (2001)
    The hydrophobin eas is largely unstructured in solution and functions by forming amyloid-like structures
    Structure 9, 83-91.

  76. Deane, J.E., Sum, E., Mackay, J.P., Lindeman, G.J., Visvader, J.E., and Matthews, J.M. (2001)
    Design, production and characterization of FLIN2 and FLIN4: the engineering of intramolecular ldb1:LMO complexes
    Protein Eng. 14, 493-9.

  77. Matthews*, J.M., Young, T.F., Tucker, S.P., and Mackay, J.P. (2000)
    The core of the respiratory syncytial virus fusion protein is a trimeric coiled coil
    J. Virol. 74, 5911-20.

  78. Matthews, J.M., Norton, R.S., Hammacher, A., and Simpson, R.J. (2000)
    The single mutation Phe173 to Ala induces a molten globule-like state in murine interleukin-6
    Biochemistry 39, 1942-50.

  79. Matthews, J.M., Kowalski, K., Liew, C.K., Sharpe, B.K., Fox, A.H., Crossley, M., and MacKay, J.P. (2000)
    A class of zinc fingers involved in protein-protein interactions biophysical characterization of CCHC fingers from fog and U-shaped
    Eur. J. Biochem. 267, 1030-8.

  80. Matthews, J.M., Hammacher, A., Howlett, G.J., and Simpson, R.J. (1998)
    Physicochemical characterization of an antagonistic human interleukin-6 dimer
    Biochemistry 37, 10671-80.

  81. Simpson, R.J., Hammacher, A., Smith, D.K., Matthews, J.M., and Ward, L.D. (1997)
    Interleukin-6: structure-function relationships
    Protein Sci 6, 929-55.

  82. Matthews, J.M., Ward, L.D., Hammacher, A., Norton, R.S., and Simpson, R.J. (1997)
    Roles of histidine 31 and tryptophan 34 in the structure, self-association, and folding of murine interleukin-6
    Biochemistry 36, 6187-96.

  83. #Zhang, J.G., #Matthews, J.M., #Ward, L.D., and Simpson, R.J. (1997)
    Disruption of the disulfide bonds of recombinant murine interleukin-6 induces formation of a partially unfolded state
    Biochemistry 36, 2380-9 #Equal First Author.

  84. Ward, L.D., Hammacher, A., Howlett, G.J., Matthews, J.M., Fabri, L., Moritz, R.L., Nice, E.C., Weinstock, J., and Simpson, R.J. (1996)
    Influence of interleukin-6 (IL-6) dimerization on formation of the high affinity hexameric IL-6.receptor complex
    J Biol Chem 271, 20138-44.

  85. Ward, L.D., Matthews, J.M., Zhang, J.G., and Simpson, R.J. (1995)
    Equilibrium denaturation of recombinant murine interleukin-6: effect of pH, denaturants, and salt on formation of folding intermediates
    Biochemistry 34, 11652-9.

  86. Matthews, J.M. and Fersht, A.R. (1995)
    Exploring the energy surface of protein folding by structure-reactivity relationships and engineered proteins: observation of Hammond behavior for the gross structure of the transition state and anti-Hammond behavior for structural elements for unfolding/folding of barnase
    Biochemistry 34, 6805-14.

  87. Matouschek, A., Matthews, J.M., Johnson, C.M., and Fersht, A.R. (1994)
    Extrapolation to water of kinetic and equilibrium data for the unfolding of barnase in urea solutions
    Protein Eng 7, 1089-95.

  88. Fersht, A.R., Itzhaki, L.S., elMasry, N.F., Matthews, J.M., and Otzen, D.E. (1994)
    Single versus parallel pathways of protein folding and fractional formation of structure in the transition state
    Proc Natl Acad Sci U S A 91, 10426-9.

  89. Schofield, P.J., Edwards, M.R., Matthews, J., and Wilson, J.R. (1992)
    The pathway of arginine catabolism in Giardia intestinalis
    Mol Biochem Parasitol 51, 29-36.

  90. Horovitz, A., Matthews, J.M., and Fersht, A.R. (1992)
    Alpha-helix stability in proteins. II. Factors that influence stability at an internal position
    J Mol Biol 227, 560-8.
Book chapters
  1. Kuchel, P.W., Easterbrook-Smith, S.B., Gysbers, V., Hancock, D.P., Johnston, J.M., Jones, A.R., and Matthews, J.M., Schaum's Outline of Biochemistry. 3rd ed. Schaum's Outline Series2009: McGraw-Hill.

  2. Mansfield, R.E., Cross, A.J., Matthews, J.M., and Mackay, J.P. (2009)
    Protein Recognition, in Amino Acids, Peptides and Proteins in Organic Chemistry, A.B. Hughes, Editor 2009, Wiley-VCH: Weinheim.

  3. Matthews, J.M. (2012)
    Defining Protein-Protein Interactions, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer

  4. Matthews, J.M. (2012)
    Postranslational Modifications, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer

  5. Matthews, J.M., Ward, L.D., J-G., Z., and Simpson, R.J. (1996)
    The association of unfolding intermediates during the equilibrium unfolding of recombinant murine interleukin-6, in Techniques in Protein Chemistry, D.R. Marshak, Editor 1996, Academic Press, Inc.: San Diego.

  6. Matthews, J.M., ed. (2012)
    Protein Dimerization and Oligomerization in Biology. Adv Exp Med Biol. Vol. 747. 2012, Landes Bioscience/Springer.

  7. Matthews, J.M., Bcl-2 Inhibitors, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer.

  8. Matthews, J.M., Mutagenic Scanning to Define Binding Hotspots, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer.

  9. Matthews, J.M., Plasticity at Protein–Protein Interaction Interfaces, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer.

  10. Matthews, J.M., Heteromeric Versus Homomeric Association of Protein Complexes, in Encyclopedia of Biophysics, G. Roberts, Editor 2012, Springer.

  11. Matthews, J.M., LIM Domain Proteins, in Brenner's Encyclopedia of Genetics, S.M.a.K. Hughes, Editor 2013, Elseveir: Oxford. p. 242-245.

  12. Matthews, J.M., Zinc finger folds and their functions, in Encyclopedia of Metalloproteins, V.U. R. Kretsinger, E. Permyakov, Editor 2013, Springer.

Lastest update: "Lab members page", on 01st Aug 2015.

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School of MB