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[Publication highlights]

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Publication highlights

  1. O'Connell, M.R., Vandevenne, M., Nguyen, C.D., Matthews, J.M., Gamsjaeger, R., Segal, D.J., and Mackay, J.P. (2012)
    Modular assembly of RanBP2-type zinc finger domains to target single-stranded RNA
    Angew Chem Int Ed Engl 51, 5371-5375. [PubMed]

  2. Mussleman, C.A., Ramirez, J., Sims, J.K., Mansfield, R.E., Oliver, S.S., Denu, J.M., Mackay, J.P., Wade, P.A., Hagman, J., and Kutateladze, T. (2012)
    Bivalent recognition of a single nucleosome by the tandem PHD fingers of CHD4 is required for CHD4-mediated repression
    Proc Natl Acad Sci USA 109, 787-792. [PubMed]

  3. Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Weinert, B., Stokes, P., Crossley, M., Mackay, J.P., and Matthews, J.M. (2011)
    The structural basis of simultaneous recruitment of LMO2 and FOG by GATA1
    Proc Natl Acad Sci USA 108, 14443-14448. [PubMed]

  4. Mackay, J. P., Font, J., and Segal, D. J. (2011)
    The prospects for designer RNA-binding domains.
    Nature Struct Mol Biol 18, 256-261. [PubMed]

  5. Loughlin, F. E., Mansfield, R. E., Vaz, P. M., McGrath A. P., Setiyaputra S., Gamsjaeger R., Chen E. S., Morris B. J., Guss J. M. ,and Mackay, J. P. (2009)
    The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences.
    Proc Natl Acad Sci USA 106, 5581-5586 (Track II). [PubMed]

  6. Matthews, J. M., Loughlin, F. E., and Mackay, J. P. (2008)
    Designed metal-binding sites in biomolecular and bioinorganic interactions.
    Curr Opin Struct Biol 18, 484-490. [PubMed]

  7. Bhati, M., Lee, C., Nancarrow, A. L., Lee, M., Craig, V. J., Bach, I., Guss, J. M., Mackay, J. P., and Matthews, J. M. (2008)
    Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
    EMBO J 27, 2018-2029. [PubMed]

  8. Gamsjaeger, R., Liew, C.K., Loughlin, F., Crossley, M., and Mackay, J.P. (2007)
    Sticky fingers: zinc fingers as protein recognition motifs.
    Trends Biochem Sci 32, 63-70. [PubMed]

  9. Kwan, A.H., Winefield, R.N., Sunde, M., Matthews, J.M., Haverkamp, R.G., Templeton, M.D., Mackay, J.P. (2006)
    Structural basis for rodlet assembly in hydrophobins.
    Proc Natl Acad Sci USA. 103, 3621-6 (Track II). [PubMed]

  10. Ryan, D. P., and Matthews, J. M. (2005)
    Protein:Protein Interactions in Human Disease.
    Curr Opin Struct Biol 15, 441-446. [PubMed]

  11. Feng, L., Zhou, S., Gu, L., Gell, D.A., Mackay, J.P., Weiss, M.J., Gow, A.J., Shi, Y. (2005)
    Structural basis of AHSP-mediated stabilization of a-hemoglobin: protection of heme by a bis-histidyl coordination.
    Nature 435, 697-701. [26.7] [PubMed]

  12. Liew, C. K., Simpson, R. J. W., Kwan, A. H., Crofts, L., Loughlin, F., Matthews, J., Crossley, M., and Mackay, J. P. (2005)
    Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction.
    Proc Natl Acad Sci USA 102, 583-588 Track II. [PubMed]

  13. Marianayagam, N. J., Sunde, M., and Matthews, J. M. (2004)
    The power of two:protein dimerization in biology.
    Trends Biochem Sci 29, 618-625. [PubMed]

  14. Deane, J. E., Ryan, D. P., Sunde, M., Maher, M. J., Guss, J. M., Visvader, J. E., and Matthews, J. M. (2004)
    Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex.
    EMBO J 23, 3589-3598. [PubMed]

  15. Feng, L., Gell, D. A., Zhou, S., Gu, L., Kong, Y., Li, J., Hu, M., Yan, N., Lee, C., Rich, A. M., Armstrong, R. S., Lay, P. A., Gow, A. J., Weiss, M. J., Mackay, J. P., and Shi, Y. (2004)
    Molecular mechanism of AHSP-mediated stabilization of a-hemoglobin.
    Cell 119, 629-640. [PubMed]

  16. Deane, J. E., Mackay, J. P., Kwan, A. H. Y., Sum, E. Y., Visvader, J. E., and Matthews, J. M. (2003)
    Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4.
    EMBO J 22, 2224-2233. [PubMed]

Lastest update: "Lab members page", on 01st Aug 2015.

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