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[Publication highlights]

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Publication highlights

  1. Vandevenne, M., O'Connell, M. R., Helder, S., Shepherd, N. E., Matthews, J. M., Kwan, A. H., Segal, D. J., and Mackay, J. P. (2014)
    Engineering Specificity Changes on a RanBP2 zinc finger that binds single-stranded RNA
    Ang Chemie 53, 7848-7852

  2. O'Connell, M.R., Vandevenne, M., Nguyen, C.D., Matthews, J.M., Gamsjaeger, R., Segal, D.J., and Mackay, J.P. (2012)
    Modular assembly of RanBP2-type zinc finger domains to target single-stranded RNA
    Angew Chem Int Ed Engl 51, 5371-5375. [PubMed]

  3. Mussleman, C.A., Ramirez, J., Sims, J.K., Mansfield, R.E., Oliver, S.S., Denu, J.M., Mackay, J.P., Wade, P.A., Hagman, J., and Kutateladze, T. (2012)
    Bivalent recognition of a single nucleosome by the tandem PHD fingers of CHD4 is required for CHD4-mediated repression
    Proc Natl Acad Sci USA 109, 787-792. [PubMed]

  4. Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Weinert, B., Stokes, P., Crossley, M., Mackay, J.P., and Matthews, J.M. (2011)
    The structural basis of simultaneous recruitment of LMO2 and FOG by GATA1
    Proc Natl Acad Sci USA 108, 14443-14448. [PubMed]

  5. Mackay, J. P., Font, J., and Segal, D. J. (2011)
    The prospects for designer RNA-binding domains.
    Nature Struct Mol Biol 18, 256-261. [PubMed]

  6. Loughlin, F. E., Mansfield, R. E., Vaz, P. M., McGrath A. P., Setiyaputra S., Gamsjaeger R., Chen E. S., Morris B. J., Guss J. M. ,and Mackay, J. P. (2009)
    The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5' splice site-like sequences.
    Proc Natl Acad Sci USA 106, 5581-5586 (Track II). [PubMed]

  7. Matthews, J. M., Loughlin, F. E., and Mackay, J. P. (2008)
    Designed metal-binding sites in biomolecular and bioinorganic interactions.
    Curr Opin Struct Biol 18, 484-490. [PubMed]

  8. Bhati, M., Lee, C., Nancarrow, A. L., Lee, M., Craig, V. J., Bach, I., Guss, J. M., Mackay, J. P., and Matthews, J. M. (2008)
    Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes.
    EMBO J 27, 2018-2029. [PubMed]

  9. Gamsjaeger, R., Liew, C.K., Loughlin, F., Crossley, M., and Mackay, J.P. (2007)
    Sticky fingers: zinc fingers as protein recognition motifs.
    Trends Biochem Sci 32, 63-70. [PubMed]

  10. Kwan, A.H., Winefield, R.N., Sunde, M., Matthews, J.M., Haverkamp, R.G., Templeton, M.D., Mackay, J.P. (2006)
    Structural basis for rodlet assembly in hydrophobins.
    Proc Natl Acad Sci USA. 103, 3621-6 (Track II). [PubMed]

  11. Ryan, D. P., and Matthews, J. M. (2005)
    Protein:Protein Interactions in Human Disease.
    Curr Opin Struct Biol 15, 441-446. [PubMed]

  12. Feng, L., Zhou, S., Gu, L., Gell, D.A., Mackay, J.P., Weiss, M.J., Gow, A.J., Shi, Y. (2005)
    Structural basis of AHSP-mediated stabilization of a-hemoglobin: protection of heme by a bis-histidyl coordination.
    Nature 435, 697-701. [26.7] [PubMed]

  13. Liew, C. K., Simpson, R. J. W., Kwan, A. H., Crofts, L., Loughlin, F., Matthews, J., Crossley, M., and Mackay, J. P. (2005)
    Zinc fingers as protein recognition motifs: structural basis for the GATA-1/Friend of GATA interaction.
    Proc Natl Acad Sci USA 102, 583-588 Track II. [PubMed]

  14. Marianayagam, N. J., Sunde, M., and Matthews, J. M. (2004)
    The power of two:protein dimerization in biology.
    Trends Biochem Sci 29, 618-625. [PubMed]

  15. Deane, J. E., Ryan, D. P., Sunde, M., Maher, M. J., Guss, J. M., Visvader, J. E., and Matthews, J. M. (2004)
    Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex.
    EMBO J 23, 3589-3598. [PubMed]

  16. Feng, L., Gell, D. A., Zhou, S., Gu, L., Kong, Y., Li, J., Hu, M., Yan, N., Lee, C., Rich, A. M., Armstrong, R. S., Lay, P. A., Gow, A. J., Weiss, M. J., Mackay, J. P., and Shi, Y. (2004)
    Molecular mechanism of AHSP-mediated stabilization of a-hemoglobin.
    Cell 119, 629-640. [PubMed]

  17. Deane, J. E., Mackay, J. P., Kwan, A. H. Y., Sum, E. Y., Visvader, J. E., and Matthews, J. M. (2003)
    Structural basis for the recognition of ldb1 by the N-terminal LIM domains of LMO2 and LMO4.
    EMBO J 22, 2224-2233. [PubMed]

Lastest update: "News", on 30th Sep 2015.

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