Publications list for Professor Jacqueline Matthews

2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Wilkinson-White, L., Matthews, J. (2014), The PA207 Peptide Inhibitor of LIM-only Protein 2 (Lmo2) Targets Zinc Finger Domains in a Non-Specific Manner. Protein and Peptide Letters. 21(2), 132-139. [Abstract]
  • Vandevenne, M., O'Connell, M., Helder, S., Shepherd, N., Matthews, J., Kwan, A., Segal, D., Mackay, J. (2014), Engineering Specificity Changes on a RanBP2 Zinc Finger that Binds Single-Stranded RNA. Angewandte Chemie. 53(30), 7848-7852. [Abstract]
  • Joseph, S., Kwan, A., Mackay, J., Cubeddu, L., Matthews, J. (2014), Backbone and side-chain assignments of a tethered complex between lmo4 and deaf-1. Biomolecular NMR Assignments. 8(1), 141-144. [Abstract]
  • Joseph, S., Kwan, A., Stokes, P., Mackay, J., Cubeddu, L., Matthews, J. (2014), The Structure of an LIM-Only Protein 4 (LMO4) and Deformed Epidermal Autoregulatory Factor-1 (DEAF1) Complex Reveals a Common Mode of Binding to LMO4. PloS One. 9(10), e109108. [Abstract]


  • Matthews, J., Lester, K., Joseph, S., Curtis, D. (2013), LIM-domain-only proteins in cancer. Nature Reviews. Cancer. 13(2), 111-122. [Abstract]
  • Gamsjaeger, R., O'Connell, M., Cubeddu, L., Shepherd, N., Lowry, J., Kwan, A., Vandevenne, M., Swanton, M., Matthews, J., Mackay, J. (2013), A structural analysis of DNA binding by myelin transcription factor 1 double zinc fingers. The Journal of Biological Chemistry. 288(49), 35180-35191. [Abstract]
  • Gadd, M., Jacques, D., Nisevic, I., Craig, V., Kwan, A., Guss, J., Matthews, J. (2013), A structural basis for the regulation of the LIM-homeodomain protein Islet 1 (Isl1) by intra- and intermolecular interactions. The Journal of Biological Chemistry. 288(30), 21924-21935. [Abstract]
  • Youngson, N., Epp, T., Roberts, A., Daxinger, L., Ashe, A., Huang, E., Lester, K., Harten, S., Kay, G., Cox, T., Matthews, J., Chong, S., Whitelaw, E. (2013), No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations. Mammalian Genome. 24(5-6), 206-217. [Abstract]
  • Gamsjaeger, R., Kariawasam, R., Bang, L., Touma, C., Nguyen, C., Matthews, J., Cubeddu, L., Mackay, J. (2013), Semi-quantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in Surface-Plasmon-Resonance competition experiments. Analytical Biochemistry. 440(2), 178-185. [Abstract]
  • Matthews, J., Potts, J. (2013), The tandem beta-zipper: modular binding of tandem domains and linear motifs. FEBS Letters. 587(8), 1164-1171. [Abstract]
  • Stokes, P., Liew, C., Kwan, A., Foo, P., Barker, H., Djamirze, A., O'Reilly, V., Visvader, J., Mackay, J., Matthews, J. (2013), Structural basis of the interaction of the breast cancer oncogene lmo4 with the tumour suppressor ctip/rbbp8. Journal of Molecular Biology. 425(7), 1101-1110. [Abstract]
  • Vandevenne, M., Jacques, D., Artuz, C., Nguyen, C., Kwan, A., Segal, D., Matthews, J., Crossley, M., Guss, J., Mackay, J. (2013), New insights into dna recognition by zinc fingers revealed by structural analysis of the oncoprotein znf217. The Journal of Biological Chemistry. 288(15), 10616-10627. [Abstract]
  • Corcilius, L., Santhakumar, G., Stone, R., Capicciotti, C., Joseph, S., Matthews, J., Ben, R., Payne, R. (2013), Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules. Bioorganic & Medicinal Chemistry. 21(12), 3569-3581. [Abstract]


  • Gadd, M., Jacques, D., Guss, J., Matthews, J. (2012), Crystallization and diffraction of an Isl1-Ldb1 complex. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications. 68(Pt 11), 1398-1401. [Abstract]
  • Dastmalchi, S., Wilkinson-White, L., Kwan, A., Gamsjaeger, R., Mackay, J., Matthews, J. (2012), Solution structure of a tethered Lmo2(LIM2) /Ldb1(LID) complex. Protein Science. 21(11), 1768-1774. [Abstract]
  • O'Connell, M., Vandevenne, M., Nguyen, C., Matthews, J., Gamsjaeger, R., Segal, D., Mackay, J. (2012), Modular Assembly of RanBP2-Type Zinc Finger Domains to Target Single-Stranded RNA. Angewandte Chemie (International Edition). 51(22), 5371-5375. [Abstract]
  • Wilkinson, B., Stone, R., Capicciotti, C., Thaysen-Andersen, M., Matthews, J., Packer, N., Ben, R., Payne, R. (2012), Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins. Angewandte Chemie (International Edition). 51(15), 3606-3610. [Abstract]
  • Hsieh, Y., Wilkinson, B., O'Connell, M., Mackay, J., Matthews, J., Payne, R. (2012), Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Organic Letters. 14(7), 1910-1913. [Abstract]
  • Liew, C., Kwan, A., Stokes, P., Mackay, J., Matthews, J. (2012), ¹H, ¹⁵N and ¹³C assignments of an intramolecular LMO4-LIM1/CtIP complex. Biomolecular NMR Assignments. 6(1), 31-34. [Abstract]
  • Hauswirth, R., Haase, B., Blatter, M., Brooks, S., Burger, D., Drögemüller, C., Gerber, V., Henke, D., Janda, J., Jude, R., Magdesian, K., Matthews, J., Poncet, P., Svansson, V., Tozaki, T., Wilkinson-White, L., Penedo, M., Rieder, S., Leeb, T. (2012), Mutations in MITF and PAX3 cause "splashed white" and other white spotting phenotypes in horses. PLoS Genetics. 8(4), e1002653. [Abstract]
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012), Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences of the United States of America. 109(8), 2878-2883. [Abstract]
  • Matthews, J., Sunde, M. (2012), Dimers, oligomers, everywhere. In: Advances in Experimental Medicine and Biology: Protein Dimerization and Oligomerization in Biology. (pp.1-18).United States: Springer Science+Business Media, LLC.
  • Bhati, M., Lee, C., Gadd, M., Jeffries, C., Kwan, A., Whitten, A., Trewhella, J., Mackay, J., Matthews, J. (2012), Solution Structure of the LIM-Homeodomain Transcription Factor Complex Lhx3/Ldb1 and the Effects of a Pituitary Mutation on Key Lhx3 Interactions. PLoS One. 7(7), e40719. [Abstract]
  • Cubeddu, L., Joseph, S., Richard, D., Matthews, J. (2012), Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4. PLoS One. 7(6), e39218. [Abstract]


  • Gadd, M., Bhati, M., Jeffries, C., Langley, D., Trewhella, J., Guss, J., Matthews, J. (2011), The structural basis for partial redundancy in a class of transcription factors, the lim-homeodomain proteins, in neural cell type specification. The Journal of biological chemistry. 286(50), 42971-80. [Abstract]
  • Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P., Crossley, M., Mackay, J., Matthews, J. (2011), Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proceedings of the National Academy of Sciences of the United States of America. 108(35), 14443-14448. [Abstract]
  • Wissmueller, S., Font, J., Liew, C., Cram, E., Schroeder, T., Turner, J., Crossley, M., Mackay, J., Matthews, J. (2011), Protein-protein interactions: Analysis of a false positive GST pulldown result. Proteins. 79(8), 2365-71. [Abstract]


  • Wilkinson-White, L., Dastmalchi, S., Kwan, A., Ryan, D., Mackay, J., Matthews, J. (2010), (1)H, (15)N and (13)C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex. Biomolecular NMR assignments. 4(2), 203-6. [Abstract]
  • Cross, A., Jeffries, C., Trewhella, J., Matthews, J. (2010), LIM domain binding proteins one and two have different oligomeric states. Journal of molecular biology. 399(1), 133-44. [Abstract]


  • Lowry, J., Gamsjaeger, R., Thong, S., Hung, W., Kwan, A., Broitman-Maduro, G., Matthews, J., Maduro, M., Mackay, J. (2009), Structural analysis of med-1 reveals unexpected diversity in the mechanism of DNA recognition by gata-type zinc finger domains. The Journal of biological chemistry. 284(0), 5827-35. [Abstract]
  • Gadd, M., Langley, D., Guss, J., Matthews, J. (2009), Crystallization and diffraction of an Lhx4-Isl2 complex. Acta crystallographica. Section F, Structural biology and crystallization communications. 65(Pt 2), 151-153. [Abstract]
  • Matthews, J., Bhati, M., Lehtomaki, E., Mansfield, R., Cubeddu, L., Mackay, J. (2009), It Takes Two to Tango: The Structure and Function of LIM, RING, PHD and MYND Domains. Current pharmaceutical design. 15(31), 3681-3696. [Abstract]
  • Lowther, J., Robinson, M., Donnelly, S., Xu, W., Stack, C., Matthews, J., Dalton, J. (2009), The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease. PLoS neglected tropical diseases. 3(1), e369. [Abstract]