Publications list for Professor Arthur Conigrave

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Brennan-Speranza, T., Conigrave, A. (2015), Osteocalcin: An Osteoblast-Derived Polypeptide Hormone that Modulates Whole Body Energy Metabolism. Calcified Tissue International. 96(1), 1-10. [Abstract]


  • Goolam, M., Ward, J., Avlani, V., Leach, K., Christopoulos, A., Conigrave, A. (2014), Roles of intraloops-2 and -3 and the proximal C-terminus in signalling pathway selection from the human calcium-sensing receptor. FEBS Letters. 588(18), 3340-3346. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Kuchel, P. (2014), Membrane flickering of the human erythrocyte: physical and chemical effectors. European Biophysics Journal. 43(4-5), 169-177. [Abstract]
  • Leach, K., Sexton, P., Christopoulos, A., Conigrave, A. (2014), Engendering biased signalling from the calcium-sensing receptor for the pharmacotherapy of diverse disorders. British Journal of Pharmacology. 171(5), 1142-1155. [Abstract]
  • Gosby, A., Conigrave, A., Raubenheimer, D., Simpson, S. (2014), Protein leverage and energy intake. Obesity Reviews. 15(3), 183-191. [Abstract]


  • Huang, X., Hancock, D., Gosby, A., McMahon, A., Solon, S., Le Couteur, D., Conigrave, A., Raubenheimer, D., Simpson, S. (2013), Effects of dietary protein to carbohydrate balance on energy intake, fat storage and heat production in mice. Obesity. 21(1), 85-92. [Abstract]
  • Conigrave, A., Ward, D. (2013), Calcium-sensing receptor (CaSR): Pharmacological properties and signaling pathways. Best Practice & Research. Clinical Endocrinology & Metabolism. 27(3), 315-331. [Abstract]
  • Brown, E., Conigrave, A. (2013), Preface. Best Practice & Research. Clinical Endocrinology & Metabolism. 27(3), 283-284. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Grieve, S., Figtree, G., Kuchel, P. (2013), Stoichiometric Relationship between Na(+) Ions Transported and Glucose Consumed in Human Erythrocytes: Bayesian Analysis of (23)Na and (13)C NMR Time Course Data. Biophysical Journal. 104(8), 1676-1684. [Abstract]
  • Avlani, V., Ma, W., Mun, H., Leach, K., Delbridge, L., Christopoulos, A., Conigrave, A. (2013), Calcium-sensing receptor-dependent activation of creb phosphorylation in hek-293 cells and human parathyroid cells. American Journal of Physiology-Endocrinology and Metabolism. 304(10), E1097-1104. [Abstract]
  • Leach, K., Wen, A., Cook, A., Sexton, P., Conigrave, A., Christopoulos, A. (2013), Impact of clinically relevant mutations on the pharmacoregulation and signaling bias of the calcium-sensing receptor by positive and negative allosteric modulators. Endocrinology. 154(3), 1105-1116. [Abstract]
  • Ujvari, B., Mun, H., Conigrave, A., Bray, A., Osterkamp, J., Halling, P., Madsen, T. (2013), Isolation breeds naivety: island living robs Australian varanid lizards of toad-toxin immunity via four-base-pair mutation. Evolution. 67(1), 289-294. [Abstract]
  • Vandenberg, J., Conigrave, A., King, G., Kirk, K. (2013), From kinetics to imaging: an NMR odyssey--a festschrift symposium in honour of Philip William Kuchel. European Biophysics Journal. 42, 1-2. [Abstract]


  • Leach, K., Wen, A., Davey, A., Sexton, P., Conigrave, A., Christopoulos, A. (2012), Identification of Molecular Phenotypes and Biased Signaling Induced by Naturally Occurring Mutations of the Human Calcium-Sensing Receptor. Endocrinology. 153(9), 4304-4316. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Kuchel, P. (2012), Quantitative model of NMR chemical shifts of (23)Na(+) induced by TmDOTP: Applications in studies of Na(+) transport in human erythrocytes. Journal of Inorganic Biochemistry. 115, 211-219. [Abstract]
  • Davey, A., Leach, K., Valant, C., Conigrave, A., Sexton, P., Christopoulos, A. (2012), Positive and Negative Allosteric Modulators Promote Biased Signaling at the Calcium-Sensing Receptor. Endocrinology. 153(3), 1232-1241. [Abstract]
  • Arulpragasam, A., Magno, A., Ingley, E., Brown, S., Conigrave, A., Ratajczak, T., Ward, B. (2012), The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor mediated rho-kinase signaling. The Biochemical journal. 441(3), 995-1006. [Abstract]


  • Tharmalingam, S., Daulat, A., Antflick, J., Ahmed, S., Nemeth, E., Angers, S., Conigrave, A., Hampson, D. (2011), The calcium-sensing receptor modulates cell adhesion and migration via integrins. The Journal of biological chemistry. 286(47), 40922-33. [Abstract]
  • Magno, A., Ingley, E., Brown, S., Conigrave, A., Ratajczak, T., Ward, B. (2011), Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling. Biochemical and Biophysical Research Communications. 412(4), 584-589. [Abstract]
  • Rybchyn, M., Slater, M., Conigrave, A., Mason, R. (2011), An Akt-dependent increase in canonical Wnt signalling and a decrease in sclerostin protein levels are involved in strontium ranelate-induced osteogenic effects in human osteoblasts. The Journal of biological chemistry. 286(27), 23771-9. [Abstract]
  • Broadhead, G., Mun, H., Avlani, V., Jourdon, O., Church, W., Christopoulos, A., Delbridge, L., Conigrave, A. (2011), Allosteric modulation of the calcium-sensing receptor by {gamma}-glutamyl peptides inhibition of PTH secretion, suppression of intracellular cAMP levels and a common mechanism of action with L-amino acids. The Journal of biological chemistry. 286(11), 8786-97. [Abstract]
  • Lazarus, S., Pretorius, C., Khafagi, F., Campion, K., Brennan, S., Conigrave, A., Brown, E., Ward, D. (2011), A novel mutation of the primary protein kinase C phosphorylation site in the calcium-sensing receptor causes autosomal dominant hypocalcemia. European journal of endocrinology / European Federation of Endocrine Societies. 164(3), 429-35. [Abstract]
  • Gosby, A., Conigrave, A., Lau, N., Iglesias, M., Hall, R., Jebb, S., Brand-Miller, J., Caterson, I., Raubenheimer, D., Simpson, S. (2011), Testing protein leverage in lean humans: a randomised controlled experimental study. PLoS One. 6(10), e25929. [Abstract]


  • Ooi, L., Zheng, Y., Zhou, H., Trivedi, T., Conigrave, A., Seibel, M., Dunstan, C. (2010), Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis. Bone. 47(4), 795-803. [Abstract]
  • Gosby, A., Campbell, C., Badaloo, A., Soares-Wynter, S., Antonelli, M., Hall, R., Martinez-Cordero, C., Jebb, S., Brand-Miller, J., Caterson, I., Conigrave, A., Forrester, T., Raubenheimer, D., Simpson, S. (2010), Design and testing of foods differing in protein to energy ratios. Appetite. 55(2), 367-70. [Abstract]
  • Conigrave, A., Hampson, D. (2010), Broad-spectrum amino acid-sensing class C G-protein coupled receptors: Molecular mechanisms, physiological significance and options for drug development. Pharmacology & therapeutics. 127(3), 252-60. [Abstract]
  • Clissold, F., Tedder, B., Conigrave, A., Simpson, S. (2010), The gastrointestinal tract as a nutrient-balancing organ. Proceedings. Biological sciences / The Royal Society. 277(1688), 1751-9. [Abstract]
  • McCormick, W., Atkinson-Dell, R., Campion, K., Mun, H., Conigrave, A., Ward, D. (2010), Increased receptor stimulation elicits differential calcium-sensing receptor(T888) dephosphorylation. The Journal of Biological Chemistry. 285(19), 14170-14177. [Abstract]
  • Hannan, F., Nesbit, M., Turner, J., Stacey, J., Cianferotti, L., Christie, P., Conigrave, A., Whyte, M., Thakker, R. (2010), Comparison of human chromosome 19q13 and syntenic region on mouse chromosome 7 reveals absence, in man, of 11.6 Mb containing four mouse calcium-sensing receptor-related sequences: relevance to familial benign hypocalciuric hypercalcaemia type 3. European journal of human genetics : EJHG. 18(4), 442-7. [Abstract]
  • Khan, M., Conigrave, A. (2010), Mechanisms of multimodal sensing by extracellular Ca(2+)-sensing receptors: a domain-based survey of requirements for binding and signalling. British Journal of Pharmacology. 159(5), 1039-1050. [Abstract]
  • Ooi, L., Zhou, H., Kalak, R., Zheng, Y., Conigrave, A., Seibel, M., Dunstan, C. (2010), Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis. Cancer research. 70(5), 1835-1844. [Abstract]


  • Szekely, D., Brennan, S., Mun, H., Conigrave, A., Kuchel, P. (2009), Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model. European biophysics journal : EBJ. 39(0), 149-65. [Abstract]
  • Mun, H., Brennan, S., Delbridge, L., Wilkinson, M., Brown, E., Conigrave, A. (2009), Adenomatous human parathyroid cells exhibit impaired sensitivity to L-amino acids. The Journal of clinical endocrinology and metabolism. 94(9), 3567-74. [Abstract]
  • Brennan, T., Rybchyn, M., Green, W., Atwa, S., Conigrave, A., Mason, R. (2009), Osteoblasts play key roles in the mechanisms of action of strontium ranelate. British journal of pharmacology. 157(7), 1291-300. [Abstract]
  • Brennan, S., Conigrave, A. (2009), Regulation of cellular signal transduction pathways by the extracellular calcium-sensing receptor. Current pharmaceutical biotechnology. 10(3), 270-81. [Abstract]