Publications list for Professor Philip William Kuchel

2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009


  • Shishmarev, D., Chapman, B., Naumann, C., Mamone, S., Kuchel, P. (2015), (1)H NMR z-spectra of acetate methyl in stretched hydrogels: Quantum-mechanical description and Markov chain Monte Carlo relaxation-parameter estimation. Journal of Magnetic Resonance. 250C, 29-36. [Abstract]


  • Kuchel, P., Naumann, C., Chapman, B., Shishmarev, D., Håkansson, P., Bacskay, G., Hush, N. (2014), NMR resonance splitting of urea in stretched hydrogels: Proton exchange and (1)H/(2)H isotopologues. Journal of Magnetic Resonance. 247, 72-80. [Abstract]
  • Torres, A., Bansal, P., Koh, J., Pagès, G., Wu, M., Kuchel, P. (2014), Structure and antimicrobial activity of platypus 'intermediate' defensin-like peptide. FEBS Letters. 588(9), 1821-1826. [Abstract]
  • Puckeridge, M., Kuchel, P. (2014), Membrane flickering of the human erythrocyte: constrained random walk used with Bayesian analysis. European Biophysics Journal. 43(4-5), 157-167. [Abstract]
  • Nagashima, K., Rao, D., Pages, G., Velan, S., Kuchel, P. (2014), Long-lived spin state of a tripeptide in stretched hydrogel. Journal of biomolecular NMR. 59(1), 31-41. [Abstract]
  • Agarwal, N., Pages, G., D' Silva, L., Said, N., Kuchel, P., Velan, S. (2014), Dependence of residual dipolar couplings on foot angle in (1)H MR spectra from skeletal muscle. Magnetic resonance imaging. 32(4), 379-384. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Kuchel, P. (2014), Membrane flickering of the human erythrocyte: physical and chemical effectors. European Biophysics Journal. 43(4-5), 169-177. [Abstract]


  • Pages, G., Puckeridge, M., Liangfeng, G., Tan, Y., Jacob, C., Garland, M., Kuchel, P. (2013), Transmembrane exchange of hyperpolarized 13C-urea in human erythrocytes: subminute timescale kinetic analysis. Biophysical Journal. 105(9), 1956-1966. [Abstract]
  • Dona, A., Landrey, K., Atkinson, F., Brand Miller, J., Kuchel, P. (2013), 1H NMR spectroscopy for the in vitro understanding of the glycaemic index. The British Journal of Nutrition. 109(11), 1934-1939. [Abstract]
  • Naumann, C., Kuchel, P. (2013), Matrix-dependent modulation of anisotropic effects on NMR spectra from (7)Li (+) and (23)Na (+) encapsulated in cryptands. European Biophysics Journal. 42(1), 17-23. [Abstract]
  • Grieve, S., Lonborg, J., Mazhar, J., Tan, T., Ho, E., Liu, C., Lay, W., Gill, A., Kuchel, P., Bhindi, R., Figtree, G. (2013), Cardiac magnetic resonance imaging of rapid VCAM-1 up-regulation in myocardial ischemia-reperfusion injury. European Biophysics Journal. 42(1), 61-70. [Abstract]
  • Kok, C., Cunningham, S., Carpenter, K., Dane, A., Siew, S., Logan, G., Kuchel, P., Alexander, I. (2013), Adeno-associated Virus-mediated Rescue of Neonatal Lethality in Argininosuccinate Synthetase-deficient Mice. Molecular Therapy. 21(10), 1823-1831. [Abstract]
  • Kuchel, P., Pages, G., Naumann, C. (2013), 'Chiral compartmentation' in metabolism: Enzyme stereo-specificity yielding evolutionary options. FEBS Letters. 587(17), 2790-2797. [Abstract]
  • Ng, C., Torres, A., Pagès, G., Kuchel, P., Vandenberg, J. (2013), Insights into hERG K(+) channel structure and function from NMR studies. European Biophysics Journal. 42(1), 71-79. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Grieve, S., Figtree, G., Kuchel, P. (2013), Stoichiometric Relationship between Na(+) Ions Transported and Glucose Consumed in Human Erythrocytes: Bayesian Analysis of (23)Na and (13)C NMR Time Course Data. Biophysical Journal. 104(8), 1676-1684. [Abstract]
  • Larkin, T., Pages, G., Chapman, B., Rasko, J., Kuchel, P. (2013), NMR q-space analysis of canonical shapes of human erythrocytes: stomatocytes, discocytes, spherocytes and echinocytes. European Biophysics Journal. 42(1), 3-16. [Abstract]


  • Puckeridge, M., Chapman, B., Kuchel, P. (2012), (7) Li(+) NMR quadrupolar splitting in stretched hydrogels: developments in relaxation time estimation from z-spectra. Magnetic Resonance in Chemistry. 50(Suppl 1), S17-S21. [Abstract]
  • Puckeridge, M., Pag��s, G., Kuchel, P. (2012), Simultaneous estimation of T(1) and the flip angle in hyperpolarized NMR experiments using acquisition at non-regular time intervals. Journal of Magnetic Resonance. 222C, 68-73. [Abstract]
  • Arakawa, K., Koh, J., Crossett, B., Torres, A., Kuchel, P. (2012), Detection of platypus-type L/D-peptide isomerase activity in aqueous extracts of papaya fruit. Biotechnology Letters. 34(9), 1659-1665. [Abstract]
  • Puckeridge, M., Chapman, B., Conigrave, A., Kuchel, P. (2012), Quantitative model of NMR chemical shifts of (23)Na(+) induced by TmDOTP: Applications in studies of Na(+) transport in human erythrocytes. Journal of Inorganic Biochemistry. 115, 211-219. [Abstract]
  • Yau, T., Kuchel, R., Koh, J., Szekely, D., Mirtschin, P., Kuchel, P. (2012), Cytoskeletal rearrangements in human red blood cells induced by snake venoms: light microscopy of shapes and NMR studies of membrane function. Cell Biology International. 36(1), 87-97. [Abstract]
  • Ng, C., Perry, M., Tan, P., Hill, A., Kuchel, P., Vandenberg, J. (2012), The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating. PLoS One. 7(2), e31640. [Abstract]


  • Kuchel, P., Naumann, C., Puckeridge, M., Chapman, B., Szekely, D. (2011), Relaxation times of spin states of all ranks and orders of quadrupolar nuclei estimated from NMR z-spectra: Markov chain Monte Carlo analysis applied to (7)Li(+) and (23)Na(+) in stretched hydrogels. Journal of magnetic resonance (San Diego, Calif. : 1997). 212(1), 40-6. [Abstract]
  • Whillier, S., Garcia, B., Chapman, B., Kuchel, P., Raftos, J. (2011), Glutamine and α-ketoglutarate as glutamate sources for glutathione synthesis in human erythrocytes. The FEBS journal. 278(17), 3152-63. [Abstract]
  • Naumann, C., Kuchel, P. (2011), (1)H and (13)C NMR studies of glycine in anisotropic media: Double-quantum transitions and the effects of chiral interactions. Journal of magnetic resonance (San Diego, Calif. : 1997). 211(1), 74-9. [Abstract]
  • Whillier, S., Raftos, J., Sparrow, R., Kuchel, P. (2011), The effects of long-term storage of human red blood cells on the glutathione synthesis rate and steady-state concentration. Transfusion. 51(7), 1450-9. [Abstract]
  • Cunningham, S., Kok, C., Dane, A., Carpenter, K., Kizana, E., Kuchel, P., Alexander, I. (2011), Induction and Prevention of Severe Hyperammonemia in the spf(ash) Mouse Model of Ornithine Transcarbamylase Deficiency Using shRNA and rAAV-mediated Gene Delivery. Molecular Therapy. 19(5), 854-9. [Abstract]
  • Dona, A., Pages, G., Gilbert, R., Kuchel, P. (2011), Starch granule characterization by kinetic analysis of their stages during enzymic hydrolysis: 1H nuclear magnetic resonance studies. Carbohydrate Polymers. 83, 1775–1786.
  • Ng, C., Hunter, M., Perry, M., Mobli, M., Ke, Y., Kuchel, P., King, G., Stock, D., Vandenberg, J. (2011), The N-terminal tail of hERG contains an amphipathic α-helix that regulates channel deactivation. PLoS One. 6(1), e16191. [Abstract]
  • Dona, A., Pages, G., Kuchel, P. (2011), Kinetics of starch hydrolysis and glucose mutarotation studied by NMR chemical exchange saturation transfer (CEST). Carbohydrate Polymers. 86(4), 1525–1532.
  • Kuchel, P. (2011), Ancient omphalos at delphi: Geometrically a space-inverting anamorphoscope. Archaeometry. 53(2), 387-395.
  • Whillier, S., Kuchel, P., Raftos, J. (2011), Oxidative Stress in Type II Diabetes Mellitus and the Role of the Endogenous Antioxidant Glutathione. In: Role of the Adipocyte in Development of Type 2 Diabetes. (pp.129-152).Croatia: InTech.


  • Pages, G., Yau, T., Kuchel, P. (2010), Erythrocyte shape reversion from echinocytes to discocytes: Kinetics via fast-measurement NMR diffusion-diffraction. Magnetic Resonance in Medicine. 64(3), 645-652. [Abstract]
  • Chapman, B., Naumann, C., Philp, D., Eliav, U., Navon, G., Kuchel, P. (2010), z-Spectra of (23)Na(+) in stretched gels: Quantitative multiple quantum analysis. Journal of Magnetic Resonance. 205(2), 260-268. [Abstract]
  • Larkin, T., Kuchel, P. (2010), Mathematical Models of Naturally "Morphed" Human Erythrocytes: Stomatocytes and Echinocytes. Bulletin of mathematical biology. 72(6), 1323-33. [Abstract]
  • Raftos, J., Whillier, S., Kuchel, P. (2010), Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data. Journal of Biological Chemistry. 285(31), 23557-23567. [Abstract]
  • Koh, J., Chow, S., Crossett, B., Kuchel, P. (2010), Mammalian Peptide Isomerase: Platypus-Type Activity Is Present in Mouse Heart. Chemistry & biodiversity. 7(6), 1603-11. [Abstract]
  • Benga, G., Chapman, B., Matei, H., Cox, G., Romeo, T., Mironescu, E., Kuchel, P. (2010), Comparative NMR studies of diffusional water permeability of red blood cells from different species: XVI Dingo (Canis familiaris dingo) and dog (Canis familiaris). Cell biology international. 34(4), 373-8. [Abstract]
  • Benga, G., Chapman, B., Cox, G., Kuchel, P. (2010), Comparative NMR studies of diffusional water permeability of red blood cells from different species: XVIII platypus (Ornithorhynchus anatinus) and saltwater crocodile (Crocodylus porosus). Cell Biology International. 34(7), 703-708. [Abstract]
  • Kuchel, P. (2010), Models of the human metabolic network: aiming to reconcile metabolomics and genomics. Genome medicine. 2, 46. [Abstract]
  • Whittington, C., Papenfuss, A., Locke, D., Mardis, E., Wilson, R., Abubucker, S., Mitreva, M., Wong, E., Hsu, A., Kuchel, P., Belov, K., Warren, W. (2010), Novel venom gene discovery in the platypus. Genome Biology. 11(9), R95. [Abstract]
  • Naumann, C., Kuchel, P. (2010), NMR of Na+, glycine and HDO in isotropic and anisotropic carrageenan gels. Polymer Chemistry. 1(7), 1109-1116. [Abstract]


  • Pages, G., Torres, A., Ju, P., Bansal, P., Alewood, P., Kuchel, P., Vandenberg, J. (2009), Structure of the pore-helix of the hERG K(+) channel. European biophysics journal : EBJ. 39(0), 111-20. [Abstract]
  • Vandenberg, J., Kuchel, P. (2009), Proteins, membranes and cells: the structure-function nexus-ASB 2008. European Biophysics Journal. 39, 1. [Abstract]
  • Larkin, T., Kuchel, P. (2009), Erythrocyte orientational and cell volume effects on NMR q-space analysis: simulations of restricted diffusion. European biophysics journal : EBJ. 39(0), 139-48. [Abstract]
  • Szekely, D., Brennan, S., Mun, H., Conigrave, A., Kuchel, P. (2009), Effectors of the frequency of calcium oscillations in HEK-293 cells: wavelet analysis and a computer model. European biophysics journal : EBJ. 39(0), 149-65. [Abstract]
  • Naumann, C., Kuchel, P. (2009), NMR (Pro)chiral discrimination using polysaccharide gels. Chemistry (Weinheim an der Bergstrasse, Germany). 15(45), 12189-91. [Abstract]
  • Szekely, D., Yau, T., Kuchel, P. (2009), Human erythrocyte flickering: temperature, ATP concentration, water transport, and cell aging, plus a computer simulation. European biophysics journal : EBJ. 38(7), 923-39. [Abstract]
  • Cunningham, S., Spinoulas, A., Carpenter, K., Wilcken, B., Kuchel, P., Alexander, I. (2009), AAV2/8-mediated Correction of OTC Deficiency Is Robust in Adult but Not Neonatal Spf(ash) Mice. Molecular Therapy. 17(8), 1340-1346. [Abstract]
  • Peslova, G., Petrak, J., Kuzelova, K., Hrdy, I., Halada, P., Kuchel, P., Soe-Lin, S., Ponka, P., Sutak, R., Becker, E., Huang, M., Suryo Rahmanto, Y., Richardson, D., Vyoral, D. (2009), Hepcidin, the hormone of iron metabolism, is bound specifically to {alpha}-2-macroglobulin in blood. Blood. 113(0), 6225-36. [Abstract]
  • Eliav, U., Naumann, C., Navon, G., Kuchel, P. (2009), Double quantum transition as the origin of the central dip in the z-spectrum of HDO in variably stretched gel. Journal of Magnetic Resonance. 198(2), 197-203. [Abstract]
  • Pilotelle-Bunner, A., Cornelius, F., Sebban, P., Kuchel, P., Clarke, R. (2009), Mechanism of Mg2+ binding in the Na+,K+-ATPase. Biophysical Journal. 96(9), 3753-3761. [Abstract]
  • Naumann, C., Mithieux, S., Szekely, D., Tu, Y., Weiss, A., Kuchel, P. (2009), "Setting paint" analogy for the hydrophobic self-association of tropoelastin into elastin-like hydrogel. Biopolymers. 91(5), 321-330. [Abstract]
  • Dona, A., Pages, G., Gilbert, R., Gaborieau, M., Kuchel, P. (2009), Kinetics of In Vitro Digestion of Starches Monitored by Time-Resolved (1)H Nuclear Magnetic Resonance. Biomacromolecules. 10(3), 638-44. [Abstract]
  • Whittington, C., Koh, J., Warren, W., Papenfuss, A., Torres, A., Kuchel, P., Belov, K. (2009), Understanding and utilising mammalian venom via a platypus venom transcriptome. Journal of proteomics. 72, 155-64. [Abstract]
  • Ju, P., Pages, G., Riek, R., Chen, P., Torres, A., Bansal, P., Kuyucak, S., Kuchel, P., Vandenberg, J. (2009), The pore domain outer helix contributes to both activation and inactivation of the hERG K+ channel. The Journal of biological chemistry. 284(0), 1000-8. [Abstract]
  • Benga, G., Chapman, B., Kuchel, P. (2009), Comparative NMR studies of diffusional water permeability of red blood cells from different species XV. Agile wallaby (Macropus agilis), red-necked wallaby (Macropus rufogriseus) and Goodfellow''s tree kangaroo (Dendrolagus goodfellowi). Comparative Biochemistry and Physiology. Part A: Molecular & Integrative Physiology. 154(1), 105-109. [Abstract]
  • Whillier, S., Raftos, J., Chapman, B., Kuchel, P. (2009), Role of N-acetylcysteine and cystine in glutathione synthesis in human erythrocytes. Redox report : communications in free radical research. 14(3), 115-124. [Abstract]
  • Cox, F., Momot, K., Kuchel, P. (2009), Magnetic-Resonance Evaluation of the Suitability of Microstructured Polymer Optical Fibers As Sensors for Ionic Aqueous Solutions. ACS Applied Materials and Interfaces. 1(1), 197-203.
  • Koh, J., Bansal, P., Torres, A., Kuchel, P. (2009), Platypus venom: source of novel compounds. Australian Journal of Zoology. 57(0), 203-210. [Abstract]
  • Larkin, T., Pages, G., Torres, A., Kuchel, P. (2009), Rapid acquisition of NMR diffusion-diffraction q-space plots from Erythrocytes with Varying Gradient Orientation. Diffusion Fundamentals. 67, 1-12.