Dr Chun-Chien Shieh

NHMRC &
CINSW Early Career Development Fellow
Central Clinical School

A28 - Physics Building
The University of Sydney


Biographical details

Dr Andy Shieh is currently a NHMRC & CINSW Early Career Research Fellow at the Radiation Physics Laboratory in Sydney Medical School. He has a background in physics, mathematics, and computaitonal science. His main interest and expertise are in mathematic and computational modelling for medical imaging. Dr Shieh's current research focuses on the development and clinical implementation of a novel real-time tumour tracking technology that will help lung cancer patients receive improved radiotherapy with fewer side effects. He is also interested in the applications machine learning in radiotherapy and health science.

Research interests

  • Radiotherapy technology.
  • Medical physics.
  • Motion compensation in lung cancer radiotherapy.
  • Mathematical and computational modelling.
  • Medical imaging.
  • Tomographic imaging.
  • Machine learning.

Teaching and supervision

  • Radiation physics.
  • Medical image processing.

Current projects

  • Real-time lung tumour tracking for improved lung cancer radiotherapy.
  • Improving the image quality of four-dimensional cone-beam computed tomography.
  • Motion-resolved imaging techniques for next-generation radiotherapy systems.

Associations

  • Radiation Physics, Sydney Medical School
  • School of Physics

Awards and honours

  • NHMRC Early Career Fellowship
  • CINSW Early Career Fellowship

Keywords

Medical imaging; Cancer; Radiotherapy; Medical physics

Clinical Specialty

Oncology

Selected grants

2017

  • Real-time In-vivo Imaging during Lung Cancer Radiotherapy; Shieh C; National Health and Medical Research Council (NHMRC)/Early Career Fellowships.
  • Real-time In-vivo Imaging during Lung Cancer Radiotherapy; Shieh C; Cancer Institute New South Wales/Early Career Fellowship.

Selected publications

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Journals

  • Shieh, C., Caillet, V., Dunbar, M., Keall, P., Booth, J., Hardcastle, N., Haddad, C., Eade, T., Feain, I. (2017). A Bayesian approach for three-dimensional markerless tumor tracking using kV imaging during lung radiotherapy. Physics in Medicine and Biology, 62(8), 3065-3080. [More Information]
  • Woodruff, H., Shieh, C., Hegi-Johnson, F., Keall, P., Kipritidis, J. (2017). Quantifying the reproducibility of lung ventilation images between 4-Dimensional Cone Beam CT and 4-Dimensional CT. Medical Physics, 44(5), 1771-1781. [More Information]
  • Feain, I., Shieh, C., White, P., O'Brien, R., Fisher, S., Counter, W., Lazarakis, P., Stewart, D., Downes, S., Jackson, M., Whelan, B., Makhija, K., Huang, C., Keall, P., et al (2016). Functional imaging equivalence and proof of concept for image-guided adaptive radiotherapy with fixed gantry and rotating couch. Advances in Radiation Oncology, 1(4), 365-372. [More Information]
  • O'Brien, R., Cooper, B., Shieh, C., Stankovic, U., Keall, P., Sonke, J. (2016). The first implementation of respiratory triggered 4DCBCT on a linear accelerator. Physics in Medicine and Biology, 61(9), 3488-3499. [More Information]
  • Shieh, C., Kipritidis, J., O'Brien, R., Cooper, B., Kuncic, Z., Keall, P. (2015). Improving thoracic four-dimensional cone-beam CT reconstruction with anatomical-adaptive image regularization (AAIR). Physics in Medicine and Biology, 60(2), 841-868. [More Information]
  • Shieh, C., Keall, P., Kuncic, Z., Huang, C., Feain, I. (2015). Markerless tumor tracking using short kilovoltage imaging arcs for lung image-guided radiotherapy. Physics in Medicine and Biology, 60(24), 9437-9454. [More Information]
  • Cooper, B., O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2015). Quantifying the image quality and dose reduction of respiratory triggered 4D cone-beam computed tomography with patient-measured breathing. Physics in Medicine and Biology, 60(24), 9493-9513. [More Information]
  • Shieh, C., Huang, C., Keall, P., Feain, I. (2015). WE-AB-303-08: Direct Lung Tumor Tracking Using Short Imaging Arcs. Medical Physics, 42(6), 3657. [More Information]
  • Shieh, C., Kipritidis, J., O'Brien, R., Kuncic, Z., Keall, P. (2014). Image quality in thoracic 4D cone-beam CT: a sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing. Medical Physics, 41(4), 041912-1-041912-18. [More Information]
  • O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2014). Optimizing 4DCBCT projection allocation to respiratory bins. Physics in Medicine and Biology, 59(19), 5631-5649. [More Information]
  • O'Brien, R., Cooper, B., Kipritidis, J., Shieh, C., Keall, P. (2014). Respiratory motion guided four dimensional cone beam computed tomography: Encompassing irregular breathing. Physics in Medicine and Biology, 59(3), 579-595. [More Information]
  • Ge, Y., O'Brien, R., Shieh, C., Booth, J., Keall, P. (2014). Toward the development of intrafraction tumor deformation tracking using a dynamic multi-leaf collimator. Medical Physics, 41(6), 061703-1-061703-10. [More Information]
  • Fair, K., Cui, X., Li, L., Shieh, C., Zheng, R., Liu, Z., Delley, B., Ford, M., Ringer, S., Stampfl, C. (2013). Hydrogen adsorption capacity of adatoms on double carbon vacancies of graphene: A trend study from first principles. Physical Review B, 87(1), 1-7. [More Information]
  • Shieh, C., Cui, X., Delley, B., Stampfl, C. (2011). Built-in electric fields and valence band offsets in InN/GaN(0001) superlattices: First-principles investigations. Journal of Applied Physics, 109(8), 083721-1-083721-8. [More Information]

2017

  • Shieh, C., Caillet, V., Dunbar, M., Keall, P., Booth, J., Hardcastle, N., Haddad, C., Eade, T., Feain, I. (2017). A Bayesian approach for three-dimensional markerless tumor tracking using kV imaging during lung radiotherapy. Physics in Medicine and Biology, 62(8), 3065-3080. [More Information]
  • Woodruff, H., Shieh, C., Hegi-Johnson, F., Keall, P., Kipritidis, J. (2017). Quantifying the reproducibility of lung ventilation images between 4-Dimensional Cone Beam CT and 4-Dimensional CT. Medical Physics, 44(5), 1771-1781. [More Information]

2016

  • Feain, I., Shieh, C., White, P., O'Brien, R., Fisher, S., Counter, W., Lazarakis, P., Stewart, D., Downes, S., Jackson, M., Whelan, B., Makhija, K., Huang, C., Keall, P., et al (2016). Functional imaging equivalence and proof of concept for image-guided adaptive radiotherapy with fixed gantry and rotating couch. Advances in Radiation Oncology, 1(4), 365-372. [More Information]
  • O'Brien, R., Cooper, B., Shieh, C., Stankovic, U., Keall, P., Sonke, J. (2016). The first implementation of respiratory triggered 4DCBCT on a linear accelerator. Physics in Medicine and Biology, 61(9), 3488-3499. [More Information]

2015

  • Shieh, C., Kipritidis, J., O'Brien, R., Cooper, B., Kuncic, Z., Keall, P. (2015). Improving thoracic four-dimensional cone-beam CT reconstruction with anatomical-adaptive image regularization (AAIR). Physics in Medicine and Biology, 60(2), 841-868. [More Information]
  • Shieh, C., Keall, P., Kuncic, Z., Huang, C., Feain, I. (2015). Markerless tumor tracking using short kilovoltage imaging arcs for lung image-guided radiotherapy. Physics in Medicine and Biology, 60(24), 9437-9454. [More Information]
  • Cooper, B., O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2015). Quantifying the image quality and dose reduction of respiratory triggered 4D cone-beam computed tomography with patient-measured breathing. Physics in Medicine and Biology, 60(24), 9493-9513. [More Information]
  • Shieh, C., Huang, C., Keall, P., Feain, I. (2015). WE-AB-303-08: Direct Lung Tumor Tracking Using Short Imaging Arcs. Medical Physics, 42(6), 3657. [More Information]

2014

  • Shieh, C., Kipritidis, J., O'Brien, R., Kuncic, Z., Keall, P. (2014). Image quality in thoracic 4D cone-beam CT: a sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing. Medical Physics, 41(4), 041912-1-041912-18. [More Information]
  • O'Brien, R., Kipritidis, J., Shieh, C., Keall, P. (2014). Optimizing 4DCBCT projection allocation to respiratory bins. Physics in Medicine and Biology, 59(19), 5631-5649. [More Information]
  • O'Brien, R., Cooper, B., Kipritidis, J., Shieh, C., Keall, P. (2014). Respiratory motion guided four dimensional cone beam computed tomography: Encompassing irregular breathing. Physics in Medicine and Biology, 59(3), 579-595. [More Information]
  • Ge, Y., O'Brien, R., Shieh, C., Booth, J., Keall, P. (2014). Toward the development of intrafraction tumor deformation tracking using a dynamic multi-leaf collimator. Medical Physics, 41(6), 061703-1-061703-10. [More Information]

2013

  • Fair, K., Cui, X., Li, L., Shieh, C., Zheng, R., Liu, Z., Delley, B., Ford, M., Ringer, S., Stampfl, C. (2013). Hydrogen adsorption capacity of adatoms on double carbon vacancies of graphene: A trend study from first principles. Physical Review B, 87(1), 1-7. [More Information]

2011

  • Shieh, C., Cui, X., Delley, B., Stampfl, C. (2011). Built-in electric fields and valence band offsets in InN/GaN(0001) superlattices: First-principles investigations. Journal of Applied Physics, 109(8), 083721-1-083721-8. [More Information]

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