Associate Professor Brian Hawkett
Director (Key Centre For Polymer Colloids)
- BSc (Hons), University of Sydney, 1974
- Dip. Ed. University of Sydney, 1979
- PhD, University of of Sydney, 1980
- Research Manager, Berger and British Paints 1980-1988
- Research Manager, ICI Specialty Chemicals, 1988-1991
- Independent Consultant, Polymerization and Pigment Dispersion, 1991-1992
- Technical Manager, Daratech P/L, 1992-1999
- Principal Research Fellow, KCPC, University of Sydney 1999- 2008
- Associate Professor and Director, KCPC, University of Sydney, 2008 to present.
Controlled radical polymerization allows a control of polymer and nanoparticle architecture that was previously only dreamt of. Reversible addition fragmentation chain transfer (RAFT) is the most versatile of the currently available controlled radical processes. We exploit this new capability in our research to design and synthesize polymer particles and composite nanoparticles for a wide range of applications.
1. Disperse phase polymerization:
- RAFT controlled radical polymerization
- Emulsion polymerization kinetics and mechanisms
- Preparation of composite nanoparticles.
2. Biomedical applications of magnetic nanoparticles:
- Hyperthermia treatment of cancer
- Targeted drug delivery
- Medical Imaging.
3. Stabilization and rheological control of concentrated emulsions.
4. Improving the efficacy and performance of agrochemical actives.
5. Conducting collaborative projects with industry.
6. Ionic liquid ferrofluids for aerospace applications.
1. Preparation of composite nanoparticles for the enhancement of paint properties; with DuluxGroup (Australia) Pty Ltd.
2. Improving the performance of explosive emulsions; with Dyno Nobel Asia Pacific Limited.
3. Recycling HDPE, Pegras Asia Pacific P/L.
4. Removing nano and microplastics from hospital laundry waste water. Pegras Asia Pacific P/L
5. Using sterically stabilised magnetic particles for sentinel lymph node detection. Ferronova P/L
6. Improving ovarian cancer treatment outcomes using sterically stabilised nanoparticles. Zeta Therapeutics P/L
7. Bromine sequestering agents. Gelion P/L
Project title | Research student |
---|---|
Targeting aberrant epigenetic mechanisms for eradication of leukaemia stem cells | Ali ZARE |
Publications
Book Chapters
- Duong, H., Nguyen, D., Neto, C., Hawkett, B. (2018). Synthesis and applications of polymeric Janus nanoparticles. In Zhiqun Lin and Bo Li (Eds.), Soft, hard, and hybrid Janus Structures: Synthesis, Self-Assembly, and Applications, (pp. 31-68). London: World Scientific Publishing. [More Information]
- Siauw, M., Hawkett, B., Perrier, S. (2012). RAFT Polymerization: A Powerful Tool for the Synthesis and Study of Oligomers. In Krzysztof Matyjaszewski; Brent S. Sumerlin and Nicolay V. Tsarevsky (Eds.), Progress in Controlled Radical Polymerization: Materials and Applications, (pp. 13-25). Washington, USA: American Chemical Society.
Journals
- Wang, Z., Weiss, A., Mithieux, S., Blum, K., Yi, T., Matsuzaki, Y., Pham, T., Hawkett, B., Shinoka, T., Breuer, C. (2024). Regional Differences in Vascular Graft Degradation and Regeneration Contribute to Dilation. Tissue Engineering - Part A. [More Information]
- Wang, Z., Shi, H., Silveira, P., Mithieux, S., Cheng Wong, W., Liu, L., Pham, T., Hawkett, B., Wang, Y., Weiss, A. (2024). Tropoelastin modulates systemic and local tissue responses to enhance wound healing. Acta Biomaterialia, 184, 54-67. [More Information]
- Priyananda, P., Nguyen, D., Huynh, V., Hawkett, B. (2023). Decohesion of a polyolefin overlay from a substrate high density polyethylene layer by impact induced stress waves. Waste Management, 171, 393-400. [More Information]
Conferences
- Jackson, B., King, L., Jain, N., Hawkett, B. (2021). Characterization of an ionic liquid ferrofluid electrospray emission pattern. 50th AIAA/ASME/SAE/ASEE Joint Propulsion Conference 2014, United States: American Institute of Aeronautics and Astronautics Inc. [More Information]
- Pham, B., Molloy, M., Gamage, H., Emerson, M., Pham, T., Paulsen, I., Hawkett, B., Engel, A. (2021). Development of nanoparticles as biosensors for diagnosis of mucosa changes in situ during colonoscopy. Sydney Cancer Conference 2021, Australia: John Wiley & Sons. [More Information]
- Wang, B., Zhu, Y., Huynh, V., Rahman, M., Hawkett, B., Sriram, S., Dao, D. (2019). Palladium nanofiber networks hydrogen sensor and hydrogen-actuated switches. 5th International Conference on Sustainable Design and Manufacturing (SDM 2018), Cham: Springer. [More Information]
Patents
- Beattie, J., Djerdjev, A., Hawkett, B., Neto, C., Priyananda, P. (2021). Use of NO/NO2 scavengers to increase sleep time for AN based emulsion explosives. Patent No. 2016314774, 2018/02843. , Turkey.
- Hawkett, B., Bryce, N., Jain, N., Hambley, T., Pham, B. (2020). Method of Treating Cancer. Patent No. 10376589, 2012245080, 2699233, 2833413, 6038881, 616780, TR201312152. , Austria, Belgium, Canada, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom.
- Hawkett, B., Nguyen, D. (2020). Polymerisation Process And Polymer Product. Patent No. 1345478, 146025, 1802662, 2005291835, 201110164797, 216264, 2172491, 2582951, 260096, 2790003, 304184, 305777, 5362988, 9731321, EP1802662, P0032364, PI0516445.1, US20130136848 A1. , Brazil, Canada, China, France, Germany, India, Indonesia, Israel, Malaysia, Mexico, South Korea, United Kingdom.
2024
- Wang, Z., Weiss, A., Mithieux, S., Blum, K., Yi, T., Matsuzaki, Y., Pham, T., Hawkett, B., Shinoka, T., Breuer, C. (2024). Regional Differences in Vascular Graft Degradation and Regeneration Contribute to Dilation. Tissue Engineering - Part A. [More Information]
- Wang, Z., Shi, H., Silveira, P., Mithieux, S., Cheng Wong, W., Liu, L., Pham, T., Hawkett, B., Wang, Y., Weiss, A. (2024). Tropoelastin modulates systemic and local tissue responses to enhance wound healing. Acta Biomaterialia, 184, 54-67. [More Information]
2023
- Priyananda, P., Nguyen, D., Huynh, V., Hawkett, B. (2023). Decohesion of a polyolefin overlay from a substrate high density polyethylene layer by impact induced stress waves. Waste Management, 171, 393-400. [More Information]
2022
- Nguyen, D., Huynh, V., Serelis, A., Davey, T., Paravagna, O., Such, C., Hawkett, B. (2022). Janus particles by simplified RAFT-based emulsion polymerization process for polymer coating. Colloid and Polymer Science, 300(4), 341-349. [More Information]
- Wang, Z., Mithieux, S., Vindin, H., Wang, Y., Zhang, M., Liu, L., Zbinden, J., Blum, K., Yi, T., Matsuzaki, Y., Oveissi, F., Lockley, K., Waterhouse, A., Pham, T., Hawkett, B., Weiss, A., et al (2022). Rapid Regeneration of a Neoartery with Elastic Lamellae. Advanced Materials. [More Information]
2021
- Mosiman, D., Chen, Y., Yang, L., Hawkett, B., Ringer, S., Mariñas, B., Cairney, J. (2021). Atom Probe Tomography of Encapsulated Hydroxyapatite Nanoparticles. Small Methods, 5(2), 2000692. [More Information]
- Beattie, J., Djerdjev, A., Hawkett, B., Neto, C., Priyananda, P. (2021). Use of NO/NO2 scavengers to increase sleep time for AN based emulsion explosives. Patent No. 2016314774, 2018/02843. , Turkey.
- Jackson, B., King, L., Jain, N., Hawkett, B. (2021). Characterization of an ionic liquid ferrofluid electrospray emission pattern. 50th AIAA/ASME/SAE/ASEE Joint Propulsion Conference 2014, United States: American Institute of Aeronautics and Astronautics Inc. [More Information]
2020
- Hawkett, B., Bryce, N., Jain, N., Hambley, T., Pham, B. (2020). Method of Treating Cancer. Patent No. 10376589, 2012245080, 2699233, 2833413, 6038881, 616780, TR201312152. , Austria, Belgium, Canada, Denmark, Finland, France, Germany, Ireland, Italy, Netherlands, New Zealand, Portugal, Spain, Switzerland, Turkey, United Kingdom.
- Madden, A., Fernandez De La Mora, J., Sabouri, H., Pham, T., Hawkett, B. (2020). How pointed can magnetized ferrofluid tips be? Physical Review Fluids, 5(5), 1-12. [More Information]
- Nguyen, D., Zhu, L., Huynh, V., Azniwati, A., Pham, T., Lam, M., Serelis, A., Davey, T., Such, C., Neto, C., Hawkett, B. (2020). Soft-hard Janus nanoparticles for polymer encapsulation of solid particulate. Polymer Chemistry, 11(35), 5610-5618. [More Information]
2019
- Hawkett, B., Ferguson, C., Gilbert, R. (2019). Aqueous Dispersions of Polymer Particles [RAFT I]. Patent No. 1463765, 2470522, 307465, 9854, HK1070082. , Canada, France, Germany, Hong Kong, India, Ireland, United Kingdom, Vietnam.
- Chen, Y., Mosiman, D., Yang, L., Pham, T., Hawkett, B., Marinas, B., Cairney, J. (2019). Atomic-scale Observation of Hydroxyapatite Nanoparticle. Microscopy and Microanalysis, 25, 2528-2529. [More Information]
- Wang, B., Zhu, Y., Huynh, V., Rahman, M., Hawkett, B., Sriram, S., Dao, D. (2019). Palladium nanofiber networks hydrogen sensor and hydrogen-actuated switches. 5th International Conference on Sustainable Design and Manufacturing (SDM 2018), Cham: Springer. [More Information]
2018
- Pham, B., Nguyen, D., Huynh, V., Pan, E., Shirodkar-Robinson, B., Carey, M., Serelis, A., Warr, G., Davey, T., Such, C., Hawkett, B. (2018). Aqueous polymeric hollow particles as an opacifier by emulsion polymerization using macro-RAFT amphiphiles. Langmuir, 34(14), 4255-4263. [More Information]
- Pham, B., Colvin, E., Pham, T., Kim, B., Fuller, E., Moon, E., Barbey, R., Yuen, S., Rickman, B., Bryce, N., Howell, V., Hawkett, B., et al (2018). Biodistribution and clearance of stable superparamagnetic maghemite iron oxide nanoparticles in mice following intraperitoneal administration. International Journal of Molecular Sciences, 19(1), 1-23. [More Information]
- Hawkett, B., Such, C., Nguyen, D. (2018). Polymer Product and Interfacial Polymerisation Process Using RAFT Agent. Patent No. 15428, 2001911, 2363419, 8779029, 8796359, PI0709848.0. , Brazil, France, Germany, Switzerland, United Kingdom, Vietnam.
2017
- Pelras, T., Duong, H., Kim, B., Hawkett, B., Muellner, M. (2017). A 'grafting from' approach to polymer nanorods for pH-triggered intracellular drug delivery. Polymer, 112, 244-251. [More Information]
- Hawkett, B., Warr, G., Jain, N., Pham, B., Wang, Y. (2017). The steric stabilization of magnetic nanoparticles at high salt concentrations for biomed applic'ns. Patent No. 10-1638201, 10-1638201, 2724004, 279459, 5663472, ZL200980128285.4, 2724004, 5663472, ZL200980128285.4. , , Canada, China, India, South Korea, Canada, China, South Korea.
- Madden, A., de la Mora, J., Jain, N., Sabouri, H., Hawkett, B. (2017). Effect of a homogeneous magnetic field on the electrospraying characteristics of sulfolane ferrofluids. Journal of Fluid Mechanics, 833, 430-444. [More Information]
2016
- Scarratt, L., Hoatson, B., Wood, E., Hawkett, B., Neto, C. (2016). Durable Superhydrophobic Surfaces via Spontaneous Wrinkling of Teflon AF. ACS Applied Materials and Interfaces, 8(10), 6743-6750. [More Information]
- Liang, S., Yunus, M., Panagiotaki, E., Kim, B., Stait-Gardner, T., Zubkov, M., Hawkett, B., Price, W., Power, C., Bourne, R. (2016). Modelling of Diffusion in Cultured Epithelial Cell Spheroids. International Society of Magnetic Resonance in Medicine 24th Annual Meeting, Singapore: International Society for Magnetic Resonance in Medicine.
- Nguyen, D., Pham, B., Huynh, V., Kim, B., Pham, T., Bickley, S., Jones, S., Serelis, A., Davey, T., Such, C., Hawkett, B. (2016). Monodispersed polymer encapsulated superparamagnetic iron oxide nanoparticles for cell labeling. Polymer, 106, 238-248. [More Information]
2015
- Polikarpov, M., Cherepanov, V., Chuev, M., Gabbasov, R., Mischenko, I., Jain, N., Jones, S., Hawkett, B., Panchenko, V. (2015). Mossbauer evaluation of the interparticle magnetic interactions within the magnetic hyperthermia beads. Journal of Magnetism and Magnetic Materials, 380, 347-352. [More Information]
- Huynh, V., Nguyen, D., Such, C., Hawkett, B. (2015). Polymer coating of graphene oxide via reversible addition-fragmentation chain transfer mediated emulsion polymerization. Journal of Polymer Science, Part A: Polymer Chemistry, 53(12), 1413-1421. [More Information]
- Priyananda, P., Djerdjev, A., Gore, J., Neto, C., Beattie, J., Hawkett, B. (2015). Premature detonation of an NH4NO3 emulsion in reactive ground. Journal of Hazardous Materials, 283, 314-320. [More Information]
2014
- Jain, N., Liu, C., Hawkett, B., Warr, G., Hamilton, W. (2014). Application of small-angle neutron scattering to the study of forces between magnetically chained monodisperse ferrofluid emulsion droplets. Journal of Applied Crystallography, 47(1), 41-52. [More Information]
- Ghasemi, S., Darestani Farahani, M., Abdollahi, Z., Hawkett, B., Gomes, V. (2014). Electrical impedance spectroscopy for determining critical micelle concentration of ionic emulsifiers. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 441, 195-203. [More Information]
- King, L., Meyer, E., Hopkins, M., Hawkett, B., Jain, N. (2014). Self-Assembling Array of Magnetoelectrostatic Jets from the Surface of a Superparamagnetic Ionic Liquid. Langmuir, 30(47), 14143-14150. [More Information]
2013
- Telford, A., Pham, B., Neto, C., Hawkett, B. (2013). Micron-sized polystyrene particles by surfactant-free emulsion polymerization in air: Synthesis and mechanism. Journal of Polymer Science, Part A: Polymer Chemistry, 51(19), 3997-4002. [More Information]
- Telford, A., Hawkett, B., Such, C., Neto, C. (2013). Mimicking the wettability of the rose petal using self-assembly of waterborne polymer particles. Chemistry of Materials, 25(17), 3472-3479. [More Information]
- Heinen (O'Donnell), J., Blom, A., Hawkett, B., Warr, G. (2013). Phase behavior of amphiphilic diblock co-oligomers with nonionic and ionic hydrophilic groups. The Journal of Physical Chemistry B, 117(10), 3005-3018. [More Information]
2012
- Hawkett, B., Hambley, T., Bryce, N., Pham, B., Jain, N. (2012). A method for the treatment of a solid tumour. Patent No. CA2833413 A1, WO2012142669 A1. , Canada.
- Hawkett, B., Jain, N., Warr, G., Wang, Y., Pham, B. (2012). Administrable Compositions (New Zealand). Patent No. 589287. New Zealand.
- Hawkett, B., Jain, N. (2012). Polymer Microgel Beads and Preparative Method Thereof (New Zealand). Patent No. 589289. New Zealand.
2011
- Konkolewicz, D., De Bruyn, H., Hawkett, B. (2011). Effect of stabilizer functionality on the kinetics of emulsion polymerization in hairy particles. Macromolecules, 44(22), 8744-8754. [More Information]
- Hawkett, B., Nguyen, D., Such, C. (2011). Polymer Product and Interfacial Polymerisation Process Using RAFT Agent (New Zealand). Patent No. 2008/09302, 571932. New Zealand, South Africa.
- Jain, N., Zhang, X., Hawkett, B., Warr, G. (2011). Stable and Water-Tolerant Ionic Liquid Ferrofluids. ACS Applied Materials and Interfaces, 3(3), 662-667. [More Information]
2010
- Such, C., Rizzardo, E., Serelis, A., Hawkett, B., Gilbert, R., Ferguson, C., Hughes, R. (2010). Aqueous Dispersions of Polymer Particles. Patent No. 1010008390000, 12004500941, 162557, 2002363814, 280619, 4405807, 533519, 7745553, CN 1625771, IDP0022848, W00200401561. , China, Indonesia, Israel, Mexico, New Zealand, Philippines, Republic of Korea.
- Priyananda, P., Hawkett, B., Warr, G. (2010). Controlling the locus of bubble nucleation by dissolved gases in heterogeneous liquid-liquid systems. Langmuir, 26(2), 684-691. [More Information]
- Pham, B., Zondanos, H., Such, C., Warr, G., Hawkett, B. (2010). Miniemulsion polymerization with arrested Ostwald ripening stabilized by amphiphilic RAFT copolymers. Macromolecules, 43(19), 7950-7957. [More Information]
2009
- Hawkett, B., Jain, N., Pham, B., Wang, Y., Warr, G. (2009). School of Chemistry, The University of Sydney. Patent No. WO2009/137890A1.
- Ahmad, N., Charleux, B., Farcet, C., Ferguson, C., Gaynor, S., Hawkett, B., Heatley, F., Klumperman, B., Konkolewicz, D., Lovell,, P., et al (2009). Chain transfer to polymer and branching in controlled radical polymerizations of n-butyl acrylate. Macromolecular Rapid Communications, 30(23), 2002-2021. [More Information]
- Sprong, E., De Bruyn, H., Such, C., Hawkett, B. (2009). Control of particle morphology in Ab initio RAFT mediated emulsion polymerization. Australian Journal of Chemistry, 62(11), 1501-1506. [More Information]
2008
- Nguyen, D., Zondanos, H., Farrugia, J., Serelis, A., Such, C., Hawkett, B. (2008). Pigment encapsulation by emulsion polymerization using macro-RAFT copolymers. Langmuir, 24(5), 2140-2150. [More Information]
- Konkolewicz, D., Hawkett, B., Gray-Weale, A., Perrier, S. (2008). RAFT Polymerization Kinetics: Combination of Apparently Conflicting Models. Macromolecules, 41(17), 6400-6412. [More Information]
2007
- Ganeva, D., Sprong, E., De Bruyn, H., Warr, G., Such, C., Hawkett, B. (2007). Particle formation in ab initio RAFT mediated emulsion polymerization systems. Macromolecules, 40(17), 6181-6189. [More Information]
2006
- Sprong, E., Leswin, J., Lamb, D., Ferguson, C., Hawkett, B., Pham, B., Nguyen, D., Such, C., Serelis, A., Gilbert, R. (2006). Molecular watchmaking: ab initio Emulsion polymerization by RAFT-controlled self-assembly. Macromolecular Symposia, 231, 84-93. [More Information]
- Mock, E., De Bruyn, H., Hawkett, B., Gilbert, R., Zukoski, C. (2006). Synthesis of anisotropic nanoparticles by seeded emulsion polymerization. Langmuir, 22(9), 4037-4043. [More Information]
2005
- Liang, G., Hawkett, B., Tanner, R. (2005). A rheological investigation of the self-assembly and adsorption behavior of a surfactant salt. Journal of Colloid and Interface Science, 292(1), 46-53. [More Information]
- Ferguson, C., Hughes, R., Nguyen, D., Pham, B., Gilbert, R., Serelis, A., Such, C., Hawkett, B. (2005). Ab initio emulsion polymerization by RAFT-controlled self-assembly. Macromolecules, 38(6), 2191-2204. [More Information]
- Sprong, E., De Bruyn, H., Ferguson, C., Nguyen, D., Hawkett, B., Gilbert, R. (2005). RAFT polymerization in emulsion systems by self-assembly: Particle size and molecular architecture. Polymer preprints, 46(2), 380-380.
2003
- Strauch, J., McDonald, J., Chapman, B., Kuchel, P., Hawkett, B., Roberts, G., Tonge, M., Gilbert, R. (2003). Diffusion coefficients of the monomer and oligomers in hydroxyethyl methacrylate. Journal of Polymer Science, Part A: Polymer Chemistry, 41(16), 2491-2501. [More Information]
- Gilbert, R., Hawkett, B. (2003). Making surface coatings with emulsion polymerization technology: the old and the new. Surface Coatings Australia, 40(5), 24-25.
- Pham, B., Nguyen, D., Ferguson, C., Hawkett, B., Serelis, A., Such, C. (2003). Miniemulsion polymerization stabilized by amphipathic marcro RAFT agents. Macromolecules, 36(24), 8907-8909. [More Information]
2002
- Ferguson, C., Hughes, R., Pham, B., Hawkett, B., Gilbert, R., Serelis, A., Such, C. (2002). Effective ab Initio Emulsion Polymerization under RAFT Control. Macromolecules, 35(25), 9243-9245. [More Information]
- Zeaiter, J., Romagnoli, J., Barton, G., Gomes, V., Hawkett, B., Gilbert, R. (2002). Operation of semi-batch emulsion polymerisation reactors: Modelling, validation and effect of operating conditions. Chemical Engineering Journal, 57(15), 2955-2969. [More Information]
- Gilbert, R., Li, F., Williams, S., Fellows, C., Hawkett, B., Gomes, V., Kalt, P., Chen, Y. (2002). Shear induced coagulation in emulsion polymerisation systems. Polymeric Materials: Science and Engineering (PMSE Preprints), 87, 504.
2000
- De Bruyn, H., Gilbert, R., Hawkett, B. (2000). Retardation by oxygen in emulsion polymerisation. Polymer, 41(24), 8633-8639. [More Information]
1990
- Hawkett, B., Napper, D., Gilbert, R. (1990). Analysis of interval III kinetic data for emulsion polymerizations. Physical Chemistry Chemical Physics, 77(10), 2395-2404. [More Information]
- Hawkett, B., Napper, D., Gilbert, R. (1990). General solution to the Smith-Ewart equation for emulsion polymerization kinetics. Journal of the Chemical Society, Faraday Transactions I, 73, 690-698. [More Information]
- Hawkett, B., Napper, D., Gilbert, R. (1990). Radical capture efficiencies in emulsion polymerization. Journal of Polymer Science, Part A: Polymer Chemistry, 19(12), 3173-3179.
Selected Grants
2023
- Safe Emulsion Explosives for High Temperature Deep Level Mining, Hawkett B, D'Alessandro D, Tanner R, Australian Research Council (ARC)/Linkage Projects (LP)
- RA - PEGRAS Asia Pacific Pty. Ltd - The synthesis of novel cationic charged polymer modified high-density solid coagulants and their use to remove microfibres from samples NSW health laundry wastewater- Phase 2, Hawkett B, Pegras Asia Pacific Pty Ltd/Research Grant
- CRC-P Nanoparticle manufacturing and its application in brain cancer radiotherapy, Hawkett B, Ferronova Pty Ltd/Cooperative Research Centre Project
2021
- Polymer nanofibers with functional properties for paint coatings, Hawkett B, Neto C, Warr G, Davey T, Paravagna O, Australian Research Council (ARC)/Linkage Projects (LP)