Dr Daniel Clayton

Postdoctoral Research Associate

F11 - Chemistry Building
The University of Sydney

Telephone +61 2 9351 5745
Fax +61 2 9351 3329

Selected publications

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Journals

  • Mitchell, N., Sayers, J., Kulkarni, S., Clayton, D., Goldys, A., Ripoll-Rozada, J., Barbosa Pereira, P., Chan, B., Radom, L., Payne, R. (2017). Accelerated protein synthesis via one-pot ligation-deselenization chemistry. Chem, 2(5), 703-715. [More Information]
  • Clayton, D., Hanchapola, I., Thomas, W., Widdop, R., Smith, A., Perlmutter, P., Aguilar, M. (2015). Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2. Frontiers in Pharmacology, 6(JAN), 1-9. [More Information]
  • Schroeder, C., Swedberg, J., Withka, J., Rosengren, K., Akcan, M., Clayton, D., Daly, N., Cheneval, O., Borzilleri, K., et al (2014). Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry and Biology, 21(2), 284-294. [More Information]
  • Mcdonald, C., Payne, N., Sun, G., Clayton, D., Del Borgo, M., Aguilar, M., Perlmutter, P., Bernard, C. (2014). Single beta3-amino acid substitutions to MOG peptides suppress the development of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology, 277(Issue 1-2), 67-76. [More Information]
  • Millard, C., Ludeman, J., Canals, M., Bridgford, J., Hinds, M., Clayton, D., Christopoulos, A., Payne, R., Stone, M. (2014). Structural basis of receptor sulfotyprosine recognition by a CC chemokine: The N-terminal region of CCR3 bound to CCL11/eotaxin-1. Structure, 22(11), 1571-1581. [More Information]
  • Feder, D., Hussein, W., Clayton, D., Kan, M., Schenk, G., McGeary, R., Guddat, L. (2012). Identification of Purple Acid Phosphatase Inhibitors by Fragment-Based Screening: Promising New Leads for Osteoporosis Therapeutics. Chemical Biology and Drug Design (Print), 80(5), 665-674. [More Information]
  • Jones, E., Del Borgo, M., Kirsch, J., Clayton, D., Bosnyak, S., Welungoda, I., Hausler, N., Unabia, S., Perlmutter, P., et al (2011). A single beta-amino acid substitution to angiotensin II confers AT 2 receptor selectivity and vascular function. Hypertension, 57(3), 570-576. [More Information]
  • Clayton, D., Hanchapola, I., Hausler, N., Unabia, S., Lew, R., Widdop, R., Smith, A., Perlmutter, P., Aguilar, M. (2011). Beta-amino acid substitution to investigate the recognition of angiotensin II (AngII) by angiotensin converting enzyme 2 (ACE2). Journal of Molecular Recognition, 24(2), 235-244. [More Information]
  • Ambaye, N., Pero, S., Gunzburg, M., Yap, M., Clayton, D., Del Borgo, M., Perlmutter, P., Aguilar, M., Shukla, G., et al (2011). Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression. Journal of Molecular Biology, 412(3), 397-411. [More Information]
  • Vella, P., Hussein, W., Leung, E., Clayton, D., Ollis, D., Mitic, N., Schenk, G., McGeary, R. (2011). The identification of new metallo-(beta)-lactamase inhibitor leads from fragment-based screening. Bioorganic and Medicinal Chemistry Letters, 21(11), 3282-3285. [More Information]
  • Zhu, J., Millard, C., Ludeman, J., Simpson, L., Clayton, D., Payne, R., Widlanski, T., Stone, M. (2011). Tyrosine Sulfation Influences the Chemokine Binding Selectivity of Peptides Derived from Chemokine Receptor CCR3. Biochemistry, 50(9), 1524-1534. [More Information]

Conferences

  • Ambaye, N., Lim, R., Clayton, D., Gunzburg, M., Price, J., Pero, S., Krag, D., Wilce, M., Aguilar, M., et al (2011). Uptake of a cell permeable G7-18NATE construct into cells and binding with the Grb7-SH2 domain. The Eighth Australian Peptide Conference: Peptides - Tools, Targets and Therapeutics, United States: John Wiley & Sons, Inc. [More Information]

2017

  • Mitchell, N., Sayers, J., Kulkarni, S., Clayton, D., Goldys, A., Ripoll-Rozada, J., Barbosa Pereira, P., Chan, B., Radom, L., Payne, R. (2017). Accelerated protein synthesis via one-pot ligation-deselenization chemistry. Chem, 2(5), 703-715. [More Information]

2015

  • Clayton, D., Hanchapola, I., Thomas, W., Widdop, R., Smith, A., Perlmutter, P., Aguilar, M. (2015). Structural determinants for binding to angiotensin converting enzyme 2 (ACE2) and angiotensin receptors 1 and 2. Frontiers in Pharmacology, 6(JAN), 1-9. [More Information]

2014

  • Schroeder, C., Swedberg, J., Withka, J., Rosengren, K., Akcan, M., Clayton, D., Daly, N., Cheneval, O., Borzilleri, K., et al (2014). Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro. Chemistry and Biology, 21(2), 284-294. [More Information]
  • Mcdonald, C., Payne, N., Sun, G., Clayton, D., Del Borgo, M., Aguilar, M., Perlmutter, P., Bernard, C. (2014). Single beta3-amino acid substitutions to MOG peptides suppress the development of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology, 277(Issue 1-2), 67-76. [More Information]
  • Millard, C., Ludeman, J., Canals, M., Bridgford, J., Hinds, M., Clayton, D., Christopoulos, A., Payne, R., Stone, M. (2014). Structural basis of receptor sulfotyprosine recognition by a CC chemokine: The N-terminal region of CCR3 bound to CCL11/eotaxin-1. Structure, 22(11), 1571-1581. [More Information]

2012

  • Feder, D., Hussein, W., Clayton, D., Kan, M., Schenk, G., McGeary, R., Guddat, L. (2012). Identification of Purple Acid Phosphatase Inhibitors by Fragment-Based Screening: Promising New Leads for Osteoporosis Therapeutics. Chemical Biology and Drug Design (Print), 80(5), 665-674. [More Information]

2011

  • Jones, E., Del Borgo, M., Kirsch, J., Clayton, D., Bosnyak, S., Welungoda, I., Hausler, N., Unabia, S., Perlmutter, P., et al (2011). A single beta-amino acid substitution to angiotensin II confers AT 2 receptor selectivity and vascular function. Hypertension, 57(3), 570-576. [More Information]
  • Clayton, D., Hanchapola, I., Hausler, N., Unabia, S., Lew, R., Widdop, R., Smith, A., Perlmutter, P., Aguilar, M. (2011). Beta-amino acid substitution to investigate the recognition of angiotensin II (AngII) by angiotensin converting enzyme 2 (ACE2). Journal of Molecular Recognition, 24(2), 235-244. [More Information]
  • Ambaye, N., Pero, S., Gunzburg, M., Yap, M., Clayton, D., Del Borgo, M., Perlmutter, P., Aguilar, M., Shukla, G., et al (2011). Structural basis of binding by cyclic nonphosphorylated peptide antagonists of Grb7 implicated in breast cancer progression. Journal of Molecular Biology, 412(3), 397-411. [More Information]
  • Vella, P., Hussein, W., Leung, E., Clayton, D., Ollis, D., Mitic, N., Schenk, G., McGeary, R. (2011). The identification of new metallo-(beta)-lactamase inhibitor leads from fragment-based screening. Bioorganic and Medicinal Chemistry Letters, 21(11), 3282-3285. [More Information]
  • Zhu, J., Millard, C., Ludeman, J., Simpson, L., Clayton, D., Payne, R., Widlanski, T., Stone, M. (2011). Tyrosine Sulfation Influences the Chemokine Binding Selectivity of Peptides Derived from Chemokine Receptor CCR3. Biochemistry, 50(9), 1524-1534. [More Information]
  • Ambaye, N., Lim, R., Clayton, D., Gunzburg, M., Price, J., Pero, S., Krag, D., Wilce, M., Aguilar, M., et al (2011). Uptake of a cell permeable G7-18NATE construct into cells and binding with the Grb7-SH2 domain. The Eighth Australian Peptide Conference: Peptides - Tools, Targets and Therapeutics, United States: John Wiley & Sons, Inc. [More Information]

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