Professor Edward Holmes
NHMRC Australia Fellow
Marie Bashir Institute for Infectious Diseases and Biosecurity, Charles Perkins Centre, Sydney Medical School
A12 - Macleay Building
The University of Sydney
|Telephone||+61 2 9351 5591|
|Fax||+61 2 9351 3890|
I joined the University of Sydney in October 2012. Prior to moving here, I worked at Penn State University (2005-2012), the University of Oxford, where I was also a Fellow of New College (1993-2004), the University of Edinburgh (1991-1993), and the University of California, Davis (1990-1991). My Ph.D. is from the University of Cambridge (1990), and I also have an undergraduate degree from University College London (1986).
I have spent most of my scientific career undertaking research aimed at revealing the principle patterns and processes of viral evolution and emergence. Although I still find work of this type fascinating, and I will continue to explore these themes, I want the molecular evolution and epidemiology I pursue to have a more direct and measurable impact on public and animal health. This will be my primary goal at the University of Sydney.
• 379 peer-reviewed papers
• 22,831 total citations (28,285 in Google Scholar)
• H-index = 80 (91 in Google Scholar)
I am an evolutionary biologist who has worked on viruses and other microbes for over 20 years. My main research theme has been to determine the mechanisms by which viruses emerge in new host species, their patterns and dynamics of spread through populations, and their major mechanisms of evolutionary change. My main research tool has been the evolutionary (largely phylogenetic) analysis of gene sequence data. As case studies I have worked on a number of important viruses of humans and other animals, such as HIV, influenza, dengue, rabies and myxoma. I have also published on a number of bacterial diseases. A good summary of my research and ideas can be found in my book on viral evolution.
Please email me if you are interested in joining my exciting research group or wish to discuss specific areas of my research program.
• American Society for Microbiology
Awards and honours
• 2011: Australia Fellow, National Health and Medical Research Council (NHMRC), Australia.
• 2010: Fogarty International Center Director’s Merit Award to the Multinational Influenza Seasonal Mortality Study Team (MISMS). National Institutes of Health, USA.
• 2010: Faculty Scholars Medal in the Life and Health Sciences. The Pennsylvania State University, USA.
• 2008: Kavli Fellow, National Academy of Sciences, USA.
• 2003: Scientific Medal for achievement in research by a zoologist under the age of 40. Zoological Society of London, UK.
• 2014-Present: Guest Professor, Chinese Center for Disease Control and Prevention, Beijing, China.
• 2009-Present: Member, The Center for Infection and Immunity, Columbia University, New York, NY, USA.
Epidemiology; Virology; Bacteriology
PhD and master's project opportunities
- Towards real time data sharing to support patient-centred care, quality health delivery, improvement programmes, performance management and research; Morris J, Roberts C, Simpson S, Kay J, Venkatesh S, Fazekas B, Arthur J, Feng D, Holmes E, James D, Yang J, Engel A; NSW Ministry of Health, Office for Health and Medical Research/Bioinformatics Collaborative Grants Program.
- Defining the evolution of pathogen virulence to enhance rabbit biocontrol; Kerr P, Holmes E, Strive T; Australian Research Council (ARC)/Discovery Projects (DP).
- Black Death genomics and the evolution of pathogen virulence; Holmes E, Poinar H, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.
- Genomic Sequencing Centers for Infectious Diseases; Wentworth D, Holmes E; National Institutes of Health (USA)/Research Support.
- Genetic variability of non-segmented negative-sense RNA virus populations and host adaptation; Holmes E, Bourhy H; Agence Nationale de la Recherche/Research Grant.
- Cluster-randomised controlled trial to test the effectiveness of facemasks in preventing influenza, corona and other respiratory viruses among Hajj pilgrims; Holmes E, Rashid H; The Qatar Foundation/Research Grant.
- The Evolutionary and Biological Bases of Host Switching in Viruses; Holmes E, Parrish C, Holmes E; National Institutes of Health (USA)/Research Support.
- Genomic analysis of the canonical case of virulence evolution: myxomatosis in Australia; Holmes E, Read A, Kerr P; National Institutes of Health (USA)/Research Support.
- Australia Fellowship; Holmes E; National Health and Medical Research Council (NHMRC)/Career Awards: Australian Fellowship.
The Evolution and Emergence of RNA Viruses (Oxford University Press, 2009)