Professor Edward Holmes
A12 - Macleay Building
The University of Sydney
|Telephone||+61 2 9351 5591|
|Fax||+61 2 9351 3890|
|Curriculum vitae||Curriculum vitae|
I joined the University of Sydney in October 2012. Prior to moving here, I worked at Penn State University (2005-2012), the University of Oxford, where I was also a Fellow of New College (1993-2004), the University of Edinburgh (1991-1993), and the University of California, Davis (1990-1991). My Ph.D. is from the University of Cambridge (1990), and I also have an undergraduate degree from University College London (1986).
I have spent most of my scientific career undertaking research aimed at revealing the principle patterns and processes of viral evolution and emergence. Although I still find work of this type fascinating, and I will continue to explore these themes, I want the molecular evolution and epidemiology I pursue to have a more direct and measurable impact on public and animal health. This will be my primary goal at the University of Sydney.
I am an evolutionary biologist who has worked on viruses and other microbes for over 20 years. My main research theme has been to determine the mechanisms by which viruses emerge in new host species, their patterns and dynamics of spread through populations, and their major mechanisms of evolutionary change. My main research tool has been the evolutionary (largely phylogenetic) analysis of gene sequence data. As case studies I have worked on a number of important viruses of humans and other animals, such as HIV, influenza, dengue, rabies and myxoma. I have also published on a number of bacterial diseases. A good summary of my research and ideas can be found in my book on viral evolution.
Please email me if you are interested in joining my exciting research group or wish to discuss specific areas of my research program.
Epidemiology; Virology; Bacteriology
PhD and master's project opportunities
- Black Death genomics and the evolution of pathogen virulence; Holmes E, Poinar H, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.
- Genomic Sequencing Centers for Infectious Diseases; Wentworth D, Holmes E; National Institutes of Health (USA)/Research Support.
- Genetic variability of non-segmented negative-sense RNA virus populations and host adaptation; Holmes E, Bourhy H; Agence Nationale de la Recherche/Research Grant.
- Cluster-randomised controlled trial to test the effectiveness of facemasks in preventing influenza, corona and other respiratory viruses among Hajj pilgrims; Holmes E, Rashid H; The Qatar Foundation/Research Grant.
- The Evolutionary and Biological Bases of Host Switching in Viruses; Holmes E, Parrish C, Holmes E; National Institutes of Health (USA)/Research Support.
- Genomic analysis of the canonical case of virulence evolution: myxomatosis in Australia; Holmes E, Read A, Kerr P; National Institutes of Health (USA)/Research Support.
- Australia Fellowship; Holmes E; National Health and Medical Research Council (NHMRC)/Career Awards: Australian Fellowship.