Dr Hamutal Mazrier

BSc (Magna Cum Laude), DVM, PhD

B01 - J.D. Stewart Building
The University of Sydney

Telephone +61 2 9351 6881

Research interests

  • Animal Genetics and Genomics, Reproduction, Paediatrics
  • Animal models for inherited Human diseases

Teaching and supervision

  • Comparative anatomy, Developmental veterinary anatomy
  • Reproduction and neonatal care
  • Veterinary Genetics

Selected grants

2017

  • Travel Grant - 46th Australasian Society for Immunology Annual Meeting, Nov 27- Dec 1, Brisbane; Mazrier H; Australasian Society for Immunology Inc./Travel Grant.

2016

  • Searching for gene variances involved in canine atopic dermatitis: A comparison between Israeli and Australian dogs from high risk breeds; Zur G, Mazrier H; Hebrew University of Jerusalem The Koret School of Veterinary Medicine/Clinical Research Grant.

2015

  • Targeting genes from primary immune system cells in a chicken embryo model of neural crest development and migration; Mazrier H; Sir Zelman Cowen Universities Fund/Academic Exchange Fellowship.
  • A 3-Dimensional application for an integrated learning of Veterinary Anatomy; Mazrier H, Burland G; DVC Education/Small Educational Innovation Grant.

Selected publications

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Journals

  • Mazrier, H., Vogelnest, L., Thomson, P., Taylor, R., Williamson, P. (2016). Canine atopic dermatitis: breed risk in Australia and evidence for a susceptible clade. Veterinary Dermatology, 27(42), 167-e42. [More Information]
  • Waud, B., Mazrier, H., Wade, C. (2016). Digging for known genetic mutations underlying inherited bone and cartilage characteristics and disorders in the dog and cat. Veterinary and Comparative Orthopaedics and Traumatology, 29(4), 269-276. [More Information]
  • Mazrier, H., Vogelnest, L., Kohl, A., Taylor, R., Sela-Donenfeld, D., Wei, J., Williamson, P. (2016). Exploring the IL7-IL7R pathway: a comparative approach confirms reduced gene expression in atopic dogs and a function in prenatal immune system development of chicks. European Journal of Immunology, 46(Suppl. 1), 1055-1055.
  • Mortlock, S., Booth, R., Mazrier, H., Khatkar, M., Williamson, P. (2016). Visualization of Genome Diversity in German Shepherd Dogs. Bioinformatics and Biology Insights, 9(2), 37-42. [More Information]
  • Mazrier, H., Thomson, P., Hollinshead, F., Dawson, M., Williamson, P. (2015). Heritability of graduation from a Guide Dog training program. Journal of Veterinary Behavior, 10(5), 447-447. [More Information]
  • Mazrier, H., Tal, S., Aizinbud, E., Bargai, U. (2006). A field investigation of the use of the pedometer for the early detection of lameness in cattle. Canadian Veterinary Journal, 47, 883-886.
  • Bargai, U., Mazrier, H. (2003). Epidemiological Aspects of Sequelae of Subclinical Laminitis. Israel Journal of Veterinary Medicine, 58(4), 97-99.
  • Mazrier, H., Van Hoeven, M., Wang, P., Knox, V., Aguirre, G., Holt, E., Weimelt, S., Sleeper, M., Hubler, M., Haskins, M., et al (2003). Inheritance, Biochemical Abnormalities, and Clinical Features of Feline Mucolipidosis II: The First Animal Model of Human I-Cell Disease. Journal of Heredity, 94(4), 363-373.
  • Haskins, M., Casal, M., Ellinwood, N., Melniczek, J., Mazrier, H., Giger, U. (2002). Animal models for mucopolysaccharidoses and their clinical relevance. Acta Paediatrica, 439, 88-97.
  • Parker Ponder, K., Melniczek, J., Xu, L., Weil, M., O'Malley, T., O'Donnell, P., Knox, V., Aguirre, G., Mazrier, H., Ellinwood, N., et al (2002). Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 99(20). [More Information]
  • Xu, L., Haskins, M., Melniczek, J., Gao, C., Weil, M., O'Malley, T., O'Donnell, P., Mazrier, H., Ellinwood, N., Zweigle, J., et al (2002). Transduction of Hepatocytes after Neonatal Delivery of a Moloney Murine Leukemia Virus Based Retroviral Vector Results in Long-Term Expression of B-Glucuronidase in Mucopolysaccharidosis VII Dogs. Molecular Therapy, 5(2), 141-153.

Conferences

  • Giger, U., Raj, K., Murrow, C., Traas, A., Erat, A., Van Hoeven, M., Mazrier, H., Haskins, M. (2015). Congenital Hypothyroidism with Goiter in Cats due to a TPO Mutation. 24th ECVIM-CA Conference, N/A: N/A.
  • Mazrier, H., Bargai, U. (2015). The cost of lameness of dairy cows in the era of intense husbandry. 38th Symposium of the Koret School of Veterinary Medicine, n/a: N/A.
  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2014). Expression of the microRNA, miR-31, is reduced in leukocytes of dogs with atopic dermatitis. Genetics Society of AustralAsia, n/a: N/A.
  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2013). Identification of a clade of dog breeds susceptible to atopic dermatitis with a unique immunophenotypic profile. Genetics Society of AustralAsia Inc Annual Conference Sydney - Genetics in the Harbour City, Sydney: Genetics Society of AustralAsia, Inc.
  • Mazrier, H., Vogelnest, L., Wei, J., Taylor, R., Williamson, P. (2012). An Integrated analysis of atopic dermatitis: Differentially expressed immunoregulatory pathways. The 8th International Conference on Advances in Canine and Feline Genomics and Inherited Disease, N/A: N/A.
  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2012). Comparative analysis of atopic dermatitis dogs identifies a clade of susceptible breeds. The seventh World Congress of Veterinary Dermatology, n/a: N/A.
  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2010). Analysis of cytokines/chemokines in canine atopic dermatitis. 40th Annual ASI conference, Australia: Australasian Society for Immunology.

2016

  • Mazrier, H., Vogelnest, L., Thomson, P., Taylor, R., Williamson, P. (2016). Canine atopic dermatitis: breed risk in Australia and evidence for a susceptible clade. Veterinary Dermatology, 27(42), 167-e42. [More Information]
  • Waud, B., Mazrier, H., Wade, C. (2016). Digging for known genetic mutations underlying inherited bone and cartilage characteristics and disorders in the dog and cat. Veterinary and Comparative Orthopaedics and Traumatology, 29(4), 269-276. [More Information]
  • Mazrier, H., Vogelnest, L., Kohl, A., Taylor, R., Sela-Donenfeld, D., Wei, J., Williamson, P. (2016). Exploring the IL7-IL7R pathway: a comparative approach confirms reduced gene expression in atopic dogs and a function in prenatal immune system development of chicks. European Journal of Immunology, 46(Suppl. 1), 1055-1055.
  • Mortlock, S., Booth, R., Mazrier, H., Khatkar, M., Williamson, P. (2016). Visualization of Genome Diversity in German Shepherd Dogs. Bioinformatics and Biology Insights, 9(2), 37-42. [More Information]

2015

  • Giger, U., Raj, K., Murrow, C., Traas, A., Erat, A., Van Hoeven, M., Mazrier, H., Haskins, M. (2015). Congenital Hypothyroidism with Goiter in Cats due to a TPO Mutation. 24th ECVIM-CA Conference, N/A: N/A.
  • Mazrier, H., Thomson, P., Hollinshead, F., Dawson, M., Williamson, P. (2015). Heritability of graduation from a Guide Dog training program. Journal of Veterinary Behavior, 10(5), 447-447. [More Information]
  • Mazrier, H., Bargai, U. (2015). The cost of lameness of dairy cows in the era of intense husbandry. 38th Symposium of the Koret School of Veterinary Medicine, n/a: N/A.

2014

  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2014). Expression of the microRNA, miR-31, is reduced in leukocytes of dogs with atopic dermatitis. Genetics Society of AustralAsia, n/a: N/A.

2013

  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2013). Identification of a clade of dog breeds susceptible to atopic dermatitis with a unique immunophenotypic profile. Genetics Society of AustralAsia Inc Annual Conference Sydney - Genetics in the Harbour City, Sydney: Genetics Society of AustralAsia, Inc.

2012

  • Mazrier, H., Vogelnest, L., Wei, J., Taylor, R., Williamson, P. (2012). An Integrated analysis of atopic dermatitis: Differentially expressed immunoregulatory pathways. The 8th International Conference on Advances in Canine and Feline Genomics and Inherited Disease, N/A: N/A.
  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2012). Comparative analysis of atopic dermatitis dogs identifies a clade of susceptible breeds. The seventh World Congress of Veterinary Dermatology, n/a: N/A.

2010

  • Mazrier, H., Vogelnest, L., Taylor, R., Williamson, P. (2010). Analysis of cytokines/chemokines in canine atopic dermatitis. 40th Annual ASI conference, Australia: Australasian Society for Immunology.

2006

  • Mazrier, H., Tal, S., Aizinbud, E., Bargai, U. (2006). A field investigation of the use of the pedometer for the early detection of lameness in cattle. Canadian Veterinary Journal, 47, 883-886.

2003

  • Bargai, U., Mazrier, H. (2003). Epidemiological Aspects of Sequelae of Subclinical Laminitis. Israel Journal of Veterinary Medicine, 58(4), 97-99.
  • Mazrier, H., Van Hoeven, M., Wang, P., Knox, V., Aguirre, G., Holt, E., Weimelt, S., Sleeper, M., Hubler, M., Haskins, M., et al (2003). Inheritance, Biochemical Abnormalities, and Clinical Features of Feline Mucolipidosis II: The First Animal Model of Human I-Cell Disease. Journal of Heredity, 94(4), 363-373.

2002

  • Haskins, M., Casal, M., Ellinwood, N., Melniczek, J., Mazrier, H., Giger, U. (2002). Animal models for mucopolysaccharidoses and their clinical relevance. Acta Paediatrica, 439, 88-97.
  • Parker Ponder, K., Melniczek, J., Xu, L., Weil, M., O'Malley, T., O'Donnell, P., Knox, V., Aguirre, G., Mazrier, H., Ellinwood, N., et al (2002). Therapeutic neonatal hepatic gene therapy in mucopolysaccharidosis VII dogs. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 99(20). [More Information]
  • Xu, L., Haskins, M., Melniczek, J., Gao, C., Weil, M., O'Malley, T., O'Donnell, P., Mazrier, H., Ellinwood, N., Zweigle, J., et al (2002). Transduction of Hepatocytes after Neonatal Delivery of a Moloney Murine Leukemia Virus Based Retroviral Vector Results in Long-Term Expression of B-Glucuronidase in Mucopolysaccharidosis VII Dogs. Molecular Therapy, 5(2), 141-153.

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