Professor Jacqueline Matthews

Professor of Protein Chemistry and NHMRC Senior Research Fellow

G08 - Biochemistry and Microbiology Building
The University of Sydney

Telephone x16025
Fax x14726

Website Related website

Research interests

The 30,000 or so genes in your genome encode proteins that work together in a coordinated fashion to regulate every biological process in the body. Jacqui Matthews' team is interested in finding out not just how proteins achieve these important biological processes, but also whether artificial regulation of these activities through the design of specific protein inhibitors is possible. In particular, they are investigating the protein-protein and protein-DNA interactions that occur during normal cellular development and comparing them with interactions that cause diseases states such as T-cell leukemia, beta-thalassaemia and breast cancer. To do this, they are using a range of techniques including:

* molecular biology * biophysical methods * structural methods

Keywords

Structural Biology; Molecular biology; Biochemistry; Breast cancer

PhD and master's project opportunities

Selected grants

2014

  • University of Sydney Automated Peptide Synthesis Platform; Payne R, Britton W, Byrne S, Chan H, Clarke R, Hunt N, Jolliffe K, Kassiou M, Lay P, Mackay J, Matthews J, McErlean C, New E, Rasmussen H, Rendina L, Rudrawar S, Rutledge P, Shepherd N; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Protein-protein interactions in the transcriptional regulation of neural development; Matthews J; Australian Research Council (ARC)/Discovery Projects (DP).
  • Developing inhibitors of the LM04 oncoprotein; Matthews J, Kwan A; Cancer Council New South Wales/Research Project Grants.

2013

  • Multiangle laser light scattering instrument for protein characterisation; Mackay J, Ataide S, Jormakka M, Ryan R, Matthews J, Shepherd N, Sunde M, Collyer C, Payne R; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • SF-61SX2/s stopped-flow fluorimeter and Service and upgrade of SX-17MV stopped-flow spectrometer; Clarke R, Davies M, Lay P, Witting P, Rasmussen H, Matthews J, Pattison D, Vandenberg J; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The Nanotemper: State-of-the-art instrumentation for the characterization of protein interactions; Payne R, Matthews J, Ataide S, Campbell I, Weiss A, Sunde M, Mackay J; Clive and Vera Ramaciotti Foundations/Awards for Biomedical Research: Major Equipment.

2011

  • Shared resource for protein discovery; Matthews J, Mabbutt B, Brown L, Paulsen I, Stock D, Sunde M, Trewhella J; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • LMO2-containing complexes in leukemia and blood cell development; Matthews J, Mackay J, Guss M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Inhibiting protein-protein interactions involved in neural development and disease; Matthews J, Cubeddu L; Australian Research Council (ARC)/Discovery Projects (DP).
  • POLARStar Omega; Sunde M, Guss M, Mackay J, Matthews J, Payne R, Cubeddu L; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2010

  • Chracterising binding partners of LMO4; Matthews J; DVC Research/Bridging Support Grant.

2009

  • Applied Biosystems 7500 Fast Real Time PCR system; Campbell I, Crossley P, Brand-Miller J, Caterson I, Hall R, Weiss A, Conigrave A, Mackay J, Matthews J, Sunde M, Gell D, Bell-Anderson K, Nicholas H, Crossett B; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Senior Research Fellowship B - 6th year extension; Matthews J; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.
  • Cracking the LIM-code: Transcription factor networks in developmental biology; Matthews J; Australian Research Council (ARC)/Discovery Projects (DP).

2008

  • 800 MHz NMR spectrometer for biomolecular structure function analysis; Vadas M, Stock D, Graham R, Shine J, Ball G, Matthews J, Gell D, Trewhella J, Rutledge P, Messerle B, Fazekas B, Vandenberg J, Mackay J, Otting G, Kuchel P; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Transcriptional complexes in haematopiesis and T-cell Leukaemia; Matthews J, Guss M, Trewhella J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • 800 MHz NMR spectrometer for biomolecular structure-function analysis; Mackay J, Otting G, Kuchel P, Matthews J, Gell D, Trewhella J, Rutledge P, Messerle B, Vadas M, Graham R, Vandenberg J, Stock D, Ball G, Fazekas B, Shine J; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2007

  • Functional assessment in the management of radiotherapy of lung cancer; Matthews J; Cancer Institute New South Wales/Research Grant.

2006

  • LIM-homeodomain Interactions in Neuronal Development; Matthews J; Australian Research Council (ARC)/Discovery Projects (DP).
  • Regulation of gene expression: biomolecular interactions in cellular development and disease; Crossley M, Crossley P, Mackay J, Matthews J; National Health and Medical Research Council (NHMRC)/Program Grants.

2005

  • Development of anti-T-ALL reagents; Crossley P, Mackay J, Matthews J; Leukaemia Foundation of NSW/Research Grant Program.
  • 4 X Memmert MEMIPP400 53 litre peltier-cooled incubators; Matthews J; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Molecular interactions of a tumor suppressor protein; Matthews J; University of Sydney/Research & Development.

2004

  • Protein complexes in CNS development; Matthews J; DVC Research/Research and Development Scheme: Research and Development (R&D).
  • Regulatory Proteins in Development and Disease; Matthews J; Sylvia and Charles Viertel Charitable Foundation/Senior Medical Research Fellowship.
  • High-resolution structures of targets for anti-cancer drugs; Matthews J; University of Sydney/Cancer Research Fund.

2003

  • Dissecting a hematopietic transcription factor complex; Matthews J, Visvader J; Australian Research Council (ARC)/Discovery Projects (DP).
  • Investigation of an LMO4- and BRCA1-containing complex involved in breast cancer; Matthews J, Visvader J; National Health and Medical Research Council (NHMRC)/Project Grants.

2002

  • Wyatt miniDawn EOS multiangle light scattering (MALLS) detector plus software; Mackay J, Matthews J, Crossley P; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Zinc fingers as pharmaceutical scaffolds; Crossley P, Mackay J, Matthews J; National Health and Medical Research Council (NHMRC)/Project Grants.

2001

  • LIM-only binding proteins: a proteomics approach; Matthews J; University of Sydney/Cancer Research Fund.

2000

  • LMO2 and Ldb1: the structure of a tumorigenic protein complex; Matthews J, Mackay J; Leo and Jenny Leukaemia and Cancer Foundation/Leukaemia and Cancer Foundation.
  • Nuclear LIM-only transcription factors: characterisation, interactions and semi-rational design of specific inhibitors; Matthews J; Australian Research Council (ARC)/Large Research Grants (LRG).
  • Zinc fingers as models for metal-dependent protein folding.; Matthews J; Australian Research Council (ARC)/Small Grants.
  • 2D-PAGE equipment and nanospray mass spectrometer adaptor for the high sensitivity identification and analysis of low abundance proteins; Matthews J; Clive & Vera Ramaciotti Foundation/Research Grants.
  • Nuclear LIM-only transcription factors: characterisation interactions and semi-rational design of specific inhibitors; Matthews J; Australian Research Council (ARC)/Australian Research Fellowship/Queen Elizabeth II Fellowship.

Selected publications

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Book Chapters

  • Matthews, J. (2013). LIM-domain Proteins. In Kelly Hughes, Stanley Maloy (Eds.), Brenner's Encyclopedia of Genetics, Second Edition, (pp. 242-245). London, UK: Academic Press Elsevier.
  • Matthews, J., Sunde, M. (2012). Dimers, Oligomers, Everywhere. In Jacqueline M Matthews (Eds.), Protein Dimerization and Oligomerization in Biology, (pp. 1-18). New York: Springer Science + Business Media.

Journals

  • Joseph, S., Kwan, A., Mackay, J., Cubeddu, L., Matthews, J. (2014). Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Biomolecular NMR Assignments, 8(1), 141-144. [More Information]
  • Gamsjaeger, R., O'Connell, M., Cubeddu, L., Shepherd, N., Lowry, J., Kwan, A., Vandevenne, M., Swanton, M., Matthews, J., Mackay, J. (2013). A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers. Journal of Biological Chemistry, 288(49), 35180-35191. [More Information]
  • Gadd, M., Jacques, D., Nisevic, I., Craig, V., Kwan, A., Guss, M., Matthews, J. (2013). A Structural Basis for the Regulation of the LIM Homeodomain Protein Islet 1 (Isl1) by Intra- and Intermolecular Interactions. Journal of Biological Chemistry, 288(30), 21924-21935. [More Information]
  • Campbell, A., Wilkinson-White, L., Mackay, J., Matthews, J., Blobel, G. (2013). Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood, 121(26), 5218-5227. [More Information]
  • Matthews, J., Lester, K., Joseph, S., Curtis, D. (2013). LIM-domain-only proteins in cancer. Nature Reviews. Cancer, 13(2), 111-122. [More Information]
  • Vandevenne, M., Jacques, D., Artuz, C., Nguyen, C., Kwan, A., Segal, D., Matthews, J., Crossley, M., Guss, M., Mackay, J. (2013). New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. Journal of Biological Chemistry, 288(15), 10616-10627. [More Information]
  • Youngson, N., Epp, T., Roberts, A., Daxinger, L., Ashe, A., Huang, E., Lester, K., Harten, S., Kay, G., Cox, T., Matthews, J., et al (2013). No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations. Mammalian Genome, 24(5-6), 206-217. [More Information]
  • Gamsjaeger, R., Kariawasam, R., Bang, L., Touma, C., Nguyen, C., Matthews, J., Cubeddu, L., Mackay, J. (2013). Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments. Analytical Biochemistry, 440(2), 178-185. [More Information]
  • Stokes, P., Liew, C., Kwan, A., Foo, P., Barker, H., Djamirze, A., O'Reilly, V., Visvader, J., Mackay, J., Matthews, J. (2013). Structural basis of the interaction of the breast cancer Oncogene LMO4 with the tumour suppressor CtIP/RBBP8. Journal of Molecular Biology, 425(7), 1101-1110. [More Information]
  • Corcilius, L., Santhakumar, G., Stone, R., Capicciotti, C., Joseph, S., Matthews, J., Ben, R., Payne, R. (2013). Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules. Bioorganic and Medicinal Chemistry, 21(12), 3569-3581. [More Information]
  • Liew, C., Kwan, A., Stokes, P., Mackay, J., Matthews, J. (2012). 1H, 15N and 13C assignments of an intramolecular LMO4-LIM1/CtIP complex. Biomolecular NMR Assignments, 6(1), 31-34. [More Information]
  • Cubeddu, L., Joseph, S., Richard, D., Matthews, J. (2012). Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4. PLoS One, 7(6), 1-8. [More Information]
  • Gadd, M., Jacques, D., Guss, M., Matthews, J. (2012). Crystallization and diffraction of an Isl1-Ldb1 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68(11), 1398-1401. [More Information]
  • O'Connell, M., Vandevenne, M., Nguyen, C., Matthews, J., Gamsjaeger, R., Segal, D., Mackay, J. (2012). Modular Assembly of RanBP2-Type Zinc Finger Domains to Target Single-Stranded RNA. Angewandte Chemie (International Edition), 51(22), 5371-5375. [More Information]
  • Hauswirth, R., Haase, B., Blatter, M., Brooks, S., Burger, D., Drogemuller, C., Gerber, V., Henke, D., Janda, J., Jude, R., Matthews, J., Wilkinson-White, L., et al (2012). Mutations in MITF and PAX3 cause " Splashed White" and Other white Spotting Phenotypes in Horses. PLoS Genetics, 8(4), 1-9. [More Information]
  • Dastmalchi, S., Wilkinson-White, L., Kwan, A., Gamsjaeger, R., Mackay, J., Matthews, J. (2012). Solution structure of a tethered Lmo2(LIM2)/Ldb1(LID) complex. Protein Science, 21(11), 1768-1774. [More Information]
  • Bhati, M., Lee, C., Gadd, M., Jeffries, C., Kwan, A., Whitten, A., Trewhella, J., Mackay, J., Matthews, J. (2012). Solution Structure of the LIM-Homeodomain Transcription Factor Complex Lhx3/Ldb1 and the Effects of a Pituitary Mutation on Key Lhx3 Interactions. PLoS One, 7(7), 1-9. [More Information]
  • Hsieh, Y., Wilkinson, B., O'Connell, M., Mackay, J., Matthews, J., Payne, R. (2012). Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Organic Letters, 14(7), 1910-1913. [More Information]
  • Wilkinson, B., Stone, R., Capicciotti, C., Thaysen-Andersen, M., Matthews, J., Packer, N., Ben, R., Payne, R. (2012). Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins. Angewandte Chemie (International Edition), 51(15), 3606-3610. [More Information]
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012). Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 109(8), 2878-2883. [More Information]
  • Wissmueller, S., Font Sadurni, J., Liew, C., Cram, E., Schroeder, T., Turner, J., Crossley, P., Mackay, J., Matthews, J. (2011). Protein-protein interactions: Analysis of a false positive GST pulldown result. Proteins: Structure, Function, and Bioinformatics, 79(8), 2365-2371. [More Information]
  • Gadd, M., Bhati, M., Jeffries, C., Langley, D., Trewhella, J., Guss, M., Matthews, J. (2011). Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification. Journal of Biological Chemistry, 286(50), 42971-42980. [More Information]
  • Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P., Crossley, M., Mackay, J., Matthews, J. (2011). Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(35), 14443-14448. [More Information]
  • Wilkinson-White, L., Dastmalchi, S., Kwan, A., Ryan, D., Mackay, J., Matthews, J. (2010). (1)H, (15)N and (13)C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex. Biomolecular N M R Assignments, 4(2), 203-206. [More Information]
  • Cross, A., Jeffries, C., Trewhella, J., Matthews, J. (2010). LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States. Journal of Molecular Biology. [More Information]
  • Gadd, M., Langley, D., Guss, M., Matthews, J. (2009). Crystallization and diffraction of an Lhx4-Isl2 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, F65(2), 151-153. [More Information]
  • Matthews, J., Bhati, M., Lehtomaki, E., Mansfield, R., Cubeddu, L., Mackay, J. (2009). It Takes Two to Tango: The Structure and Function of LIM, RING, PHD and MYND Domains. Current Pharmaceutical Design, 15(31), 3681-3969. [More Information]
  • Lowry, J., Gamsjaeger, R., Thong, S., Hung, W., Kwan, A., Broitman-Maduro, G., Matthews, J., Maduro, M., Mackay, J. (2009). Structural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domains. Journal of Biological Chemistry, 284(9), 5827-5835. [More Information]
  • Lowther, J., Robinson, M., Donnelly, S., Xu, W., Stack, C., Matthews, J., Dalton, J. (2009). The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease. PLoS Neglected Tropical Diseases, 3(1), e369 - 1-e369 - 11. [More Information]
  • Ryan, D., Duncan, J., Lee, C., Kuchel, P., Matthews, J. (2008). Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12. Proteins: Structure, Function, and Bioinformatics, 70, 1461-1474. [More Information]
  • Pilotelle-Bunner, A., Matthews, J., Cornelius, F., Apell, H., Sebban, P., Clarke, R. (2008). ATP Binding Equilibria of the Na(+),K(+)-ATPase. Biochemistry, 47(49), 13103-13114. [More Information]
  • Matthews, J., Bhati, M., Craig, V., Deane, J., Jeffries, C., Lee, C., Nancarrow, A., Ryan, D., Sunde, M. (2008). Competition between LIM-binding domains. Biochemical Society Transactions, 36(6), 1393-1397. [More Information]
  • Bhati, M., Lee, M., Nancarrow, A., Bach, I., Guss, M., Matthews, J. (2008). Crystallization of an Lhx3-Isl1 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64(4), 297-299. [More Information]
  • Matthews, J., Loughlin, F., Mackay, J. (2008). Designed metal-binding sites in biomolecular and bioinorganic interactions. Current Opinion in Structural Biology, 18, 484-490. [More Information]
  • Bhati, M., Lee, C., Nancarrow, A., Lee, M., Craig, V., Bach, I., Guss, M., Mackay, J., Matthews, J. (2008). Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. The EMBO Journal, 27, 2018-2029. [More Information]
  • Gamsjaeger, R., Swanton, M., Kobus, F., Lehtomaki, E., Lowry, J., Kwan, A., Matthews, J., Mackay, J. (2008). Structural and biophysical analysis of the DNA-binding properties of myelin transcription factor 1. Journal of Biological Chemistry, 283(8), 5158-5167. [More Information]
  • Stokes, P., Thompson, L., Marianayagam, N., Matthews, J. (2007). Dimerization of CtIP may stabilize in vivo interactions with the Retinoblastoma-pocket domain. Biochemical and Biophysical Research Communications, 354(1), 197-202. [More Information]
  • Porter, C., Matthews, J., Mackay, J., Pursglove, S., Schmidberger, J., Leedman, P., Pero, S., Krag, D., Wilce, M., Wilce, J. (2007). Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. B M C Structural Biology, 7(Article number 58), 1-15.
  • Chong, S., Vickaryous, N., Ashe, A., Zamudio, N., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J., Scott, H., Blewitt, M., et al (2007). Modifiers of epigenetic reprogramming show paternal effects in the mouse. Nature Genetics, 39(5), 614-622. [More Information]
  • Mackay, J., Sunde, M., Lowry, J., Crossley, P., Matthews, J. (2007). Protein interactions: is seeing believing? Trends in Biochemical Sciences, 32(12), 530-531. [More Information]
  • Ely, L., Beddoe, T., Clements, C., Matthews, J., Purcell, A., Kjer-Nielsen, L., McCluskey, J., Rossjohn, J. (2006). Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(17), 6641-6646. [More Information]
  • Ryan, D., Sunde, M., Kwan, A., Marianayagam, N., Nancarrow, A., vanden Hoven, R., Thompson, L., Baca, M., Mackay, J., Visvader, J., Matthews, J. (2006). Identification of the key LMO2-binding determinants on Ldb1. Journal of Molecular Biology. [More Information]
  • Begg, G., Carrington, L., Stokes, P., Matthews, J., Wouters, M., Husain, A., Lorand, L., Iismaa, S., Graham, R. (2006). Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(52), 19683-19688. [More Information]
  • Begg, G., Holman, S., Stokes, P., Matthews, J., Graham, R., Iismaa, S. (2006). Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity. Journal of Biological Chemistry, 281(18), 12603-12609. [More Information]
  • Jeffries, C., Graham, S., Stokes, P., Collyer, C., Guss, M., Matthews, J. (2006). Stabilization of a binary protein complex by intein-mediated cyclization. Protein Science, 15(11), 2612-2618. [More Information]
  • Kwan, A., Winefield, R., Sunde, M., Matthews, J., Haverkamp, R., Templeton, M., Mackay, J. (2006). Structural basis for rodlet assembly in fungal hydrophobins. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(10), 3621-3626. [More Information]
  • Lee, C., Nancarrow, A., Bach, I., Mackay, J., Matthews, J. (2005). 1H, 15N and 13C assignments of an intramolecular Lhx3:ldb1 complex. Journal of Biomolecular NMR, 33(3), 198-198. [More Information]
  • Duggin, I., Matthews, J., Dixon, N., Wake, R., Mackay, J. (2005). A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis. Journal of Biological Chemistry, 280(13), 13105-13113. [More Information]
  • Sharpe, B., Liew, C., Kwan, A., Wilce, J., Crossley, P., Matthews, J., Mackay, J. (2005). Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting. Structure, 13(2), 257-266. [More Information]
  • Ryan, D., Matthews, J. (2005). Protein-protein interactions in human disease. Current Opinion in Structural Biology, 15(4), 441-446. [More Information]
  • Williams, N., Liepinsh, E., Watt, S., Prosselkov, P., Matthews, J., Attard, P., Beck, J., Dixon, N., Otting, G. (2005). Stabilization of native protein fold by intein-mediated covalent cyclization. Journal of Molecular Biology, 346(4), 1095-1108.
  • Liew, C., Simpson, R., Kwan, A., Crofts, L., Loughlin, F., Matthews, J., Crossley, P., Mackay, J. (2005). Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/ Friend of GATA interaction. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 102(3), 583-588. [More Information]
  • Simpson, R., Lee, S., Bartle, N., Sum, E., Visvader, J., Matthews, J., Mackay, J., Crossley, P. (2004). A Classic Zinc Finger From Friend Of Gata Mediates An Interaction With The Coiled-Coil Of Transforming Acidic Coiled-Coil 3. Journal of Biological Chemistry, 279(38), 39789-39797.
  • Dubin, M., Stokes, P., Sum, E., Williams, R., Valova, V., Robinson, P., Lindeman, G., Glover, J., Visvader, J., Matthews, J. (2004). Dimerization Of CtIP, A BRCA1- And CtBP-Interacting Protein, Is Mediated By An N-Terminal Coiled-Coil Motif. Journal of Biological Chemistry, 279(26), 26932-26938.
  • Westman, B., Perdomo, J., Matthews, J., Crossley, P., Mackay, J. (2004). Structural Studies On A Protein-Binding Zinc-Finger Domain Of Eos Reveal Both Similarities And Differences To Classical Zinc Fingers. Biochemistry, 43(42), 13318-13327.
  • Deane, J., Ryan, D., Sunde, M., Maher, M., Guss, M., Visvader, J., Matthews, J. (2004). Tandem Lim Domains Provide Synergistic Binding In The LMO4:Ldb1 Complex. The EMBO Journal, 23(18), 3589-3598.
  • Sunde, M., McGrath, K., Young, L., Matthews, J., Chua, E., Mackay, J., Heather, A. (2004). Tc-1 Is A Novel Tumorigenic And Natively Disordered Protein Associated With Thyroid Cancer. Cancer Research, 64(8), 2766-2773.
  • Marianayagam, N., Sunde, M., Matthews, J. (2004). The Power Of Two: Protein Dimerization In Biology. Trends in Biochemical Sciences, 29(11), 618-625.
  • Simpson, R., Cram, E., Czolij, T., Matthews, J., Crossley, P., Mackay, J. (2003). CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. Journal of Biological Chemistry, 278(30), 28011-28018.
  • Deane, J., Maher, M., Langley, D., Graham, S., Visvader, J., Guss, M., Matthews, J. (2003). Crystallization of FLINC4, an intramolecular LM04-ldb1 complex. Acta Crystallographica. Section D: Biological Crystallography, 59(8), 1484-1486.
  • Kwan, A., Gell, D., Verger, A., Crossley, P., Matthews, J., Mackay, J. (2003). Engineering a protein scaffold from a PhD finger. Structure, 11(7), 803-813.
  • Matthews, J., Visvader, J. (2003). LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins. EMBO Reports, 4(12), 1132-1137.
  • Deane, J., Mackay, J., Kwan, A., Sum, E., Visvader, J., Matthews, J. (2003). Structural basis for the recognition of Idb1 by the N-terminal LIM domains of LM02 and LM04. The EMBO Journal, 22(9), 2224-2233.
  • Turner, J., Nicholas, H., Bishop, D., Matthews, J., Crossley, P. (2003). The LIM protein FHL3 binds basic Kruppel-like factor/Kruppel-like factor 3 and its co-repressor C-teminal-binding protein 2. Journal of Biological Chemistry, 278(15), 12786-12795.
  • Sharpe, B., Matthews, J., Kwan, A., Newton, A., Gell, D., Crossley, P., Mackay, J. (2002). A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. Structure, 10(5), 639-648.
  • Kowalski, K., Liew, C., Matthews, J., Gell, D., Crossley, P., Mackay, J. (2002). Characterization of the conserved interaction between GATA and FOG family proteins. Journal of Biological Chemistry, 277(38), 35720-35729.
  • Deane, J., Visvader, J., Mackay, J., Matthews, J. (2002). Letter to the Editor: 1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex. Journal of Biomolecular NMR, 23(2), 165-166.
  • Warton, K., Tonini, R., Fairlie, W., Matthews, J., Valenzuela, S., Qiu, M., Wu, W., Pankhurst, S., Bauskin, A., Harrop, S., et al (2002). Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in chinese hamster ovary cells expressing CLIC1. Journal of Biological Chemistry, 277(29), 26003-26011.
  • Matthews, J., Sunde, M. (2002). Zinc fingers- folds for many occasions. IUBMB Life, 54(6), 351-355.
  • Deane, J., Sum, E., Mackay, J., Lindeman, G., Visvader, J., Matthews, J. (2001). Design, production and characterization of FLIN2 and FLIN4: the engineering of intramolecular ldb1: LMO complexes. Protein Engineering, 14, 493-499.
  • Matthews, J., Visvader, J., Mackay, J. (2001). Letter to the Editor: 1H, 15N and 13C assignments of FLIN2, an intramolecular LMO2:ldb1 complex. Journal of Biomolecular NMR, 21(4), 385-386.
  • Mackay, J., Matthews, J., Winefield, R., Mackay, L., Haverkamp, R., Templeton, M. (2001). The hydrophobin EAS is largely unstructured in solution and functions by forming amyloid-like structures. Structure, 9, 83-91.

Conferences

  • Marianayagam, N., Sunde, M., Matthews, J. (2004). Biophysical Characterization Of The Interaction Of Ldb1 With Lm02.

2014

  • Joseph, S., Kwan, A., Mackay, J., Cubeddu, L., Matthews, J. (2014). Backbone and side-chain assignments of a tethered complex between LMO4 and DEAF-1. Biomolecular NMR Assignments, 8(1), 141-144. [More Information]

2013

  • Gamsjaeger, R., O'Connell, M., Cubeddu, L., Shepherd, N., Lowry, J., Kwan, A., Vandevenne, M., Swanton, M., Matthews, J., Mackay, J. (2013). A Structural Analysis of DNA Binding by Myelin Transcription Factor 1 Double Zinc Fingers. Journal of Biological Chemistry, 288(49), 35180-35191. [More Information]
  • Gadd, M., Jacques, D., Nisevic, I., Craig, V., Kwan, A., Guss, M., Matthews, J. (2013). A Structural Basis for the Regulation of the LIM Homeodomain Protein Islet 1 (Isl1) by Intra- and Intermolecular Interactions. Journal of Biological Chemistry, 288(30), 21924-21935. [More Information]
  • Campbell, A., Wilkinson-White, L., Mackay, J., Matthews, J., Blobel, G. (2013). Analysis of disease-causing GATA1 mutations in murine gene complementation systems. Blood, 121(26), 5218-5227. [More Information]
  • Matthews, J. (2013). LIM-domain Proteins. In Kelly Hughes, Stanley Maloy (Eds.), Brenner's Encyclopedia of Genetics, Second Edition, (pp. 242-245). London, UK: Academic Press Elsevier.
  • Matthews, J., Lester, K., Joseph, S., Curtis, D. (2013). LIM-domain-only proteins in cancer. Nature Reviews. Cancer, 13(2), 111-122. [More Information]
  • Vandevenne, M., Jacques, D., Artuz, C., Nguyen, C., Kwan, A., Segal, D., Matthews, J., Crossley, M., Guss, M., Mackay, J. (2013). New insights into DNA recognition by zinc fingers revealed by structural analysis of the oncoprotein ZNF217. Journal of Biological Chemistry, 288(15), 10616-10627. [More Information]
  • Youngson, N., Epp, T., Roberts, A., Daxinger, L., Ashe, A., Huang, E., Lester, K., Harten, S., Kay, G., Cox, T., Matthews, J., et al (2013). No evidence for cumulative effects in a Dnmt3b hypomorph across multiple generations. Mammalian Genome, 24(5-6), 206-217. [More Information]
  • Gamsjaeger, R., Kariawasam, R., Bang, L., Touma, C., Nguyen, C., Matthews, J., Cubeddu, L., Mackay, J. (2013). Semiquantitative and quantitative analysis of protein-DNA interactions using steady-state measurements in surface plasmon resonance competition experiments. Analytical Biochemistry, 440(2), 178-185. [More Information]
  • Stokes, P., Liew, C., Kwan, A., Foo, P., Barker, H., Djamirze, A., O'Reilly, V., Visvader, J., Mackay, J., Matthews, J. (2013). Structural basis of the interaction of the breast cancer Oncogene LMO4 with the tumour suppressor CtIP/RBBP8. Journal of Molecular Biology, 425(7), 1101-1110. [More Information]
  • Corcilius, L., Santhakumar, G., Stone, R., Capicciotti, C., Joseph, S., Matthews, J., Ben, R., Payne, R. (2013). Synthesis of peptides and glycopeptides with polyproline II helical topology as potential antifreeze molecules. Bioorganic and Medicinal Chemistry, 21(12), 3569-3581. [More Information]

2012

  • Liew, C., Kwan, A., Stokes, P., Mackay, J., Matthews, J. (2012). 1H, 15N and 13C assignments of an intramolecular LMO4-LIM1/CtIP complex. Biomolecular NMR Assignments, 6(1), 31-34. [More Information]
  • Cubeddu, L., Joseph, S., Richard, D., Matthews, J. (2012). Contribution of DEAF1 Structural Domains to the Interaction with the Breast Cancer Oncogene LMO4. PLoS One, 7(6), 1-8. [More Information]
  • Gadd, M., Jacques, D., Guss, M., Matthews, J. (2012). Crystallization and diffraction of an Isl1-Ldb1 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 68(11), 1398-1401. [More Information]
  • Matthews, J., Sunde, M. (2012). Dimers, Oligomers, Everywhere. In Jacqueline M Matthews (Eds.), Protein Dimerization and Oligomerization in Biology, (pp. 1-18). New York: Springer Science + Business Media.
  • O'Connell, M., Vandevenne, M., Nguyen, C., Matthews, J., Gamsjaeger, R., Segal, D., Mackay, J. (2012). Modular Assembly of RanBP2-Type Zinc Finger Domains to Target Single-Stranded RNA. Angewandte Chemie (International Edition), 51(22), 5371-5375. [More Information]
  • Hauswirth, R., Haase, B., Blatter, M., Brooks, S., Burger, D., Drogemuller, C., Gerber, V., Henke, D., Janda, J., Jude, R., Matthews, J., Wilkinson-White, L., et al (2012). Mutations in MITF and PAX3 cause " Splashed White" and Other white Spotting Phenotypes in Horses. PLoS Genetics, 8(4), 1-9. [More Information]
  • Dastmalchi, S., Wilkinson-White, L., Kwan, A., Gamsjaeger, R., Mackay, J., Matthews, J. (2012). Solution structure of a tethered Lmo2(LIM2)/Ldb1(LID) complex. Protein Science, 21(11), 1768-1774. [More Information]
  • Bhati, M., Lee, C., Gadd, M., Jeffries, C., Kwan, A., Whitten, A., Trewhella, J., Mackay, J., Matthews, J. (2012). Solution Structure of the LIM-Homeodomain Transcription Factor Complex Lhx3/Ldb1 and the Effects of a Pituitary Mutation on Key Lhx3 Interactions. PLoS One, 7(7), 1-9. [More Information]
  • Hsieh, Y., Wilkinson, B., O'Connell, M., Mackay, J., Matthews, J., Payne, R. (2012). Synthesis of the bacteriocin glycopeptide sublancin 168 and S-glycosylated variants. Organic Letters, 14(7), 1910-1913. [More Information]
  • Wilkinson, B., Stone, R., Capicciotti, C., Thaysen-Andersen, M., Matthews, J., Packer, N., Ben, R., Payne, R. (2012). Total synthesis of homogeneous antifreeze glycopeptides and glycoproteins. Angewandte Chemie (International Edition), 51(15), 3606-3610. [More Information]
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012). Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 109(8), 2878-2883. [More Information]

2011

  • Wissmueller, S., Font Sadurni, J., Liew, C., Cram, E., Schroeder, T., Turner, J., Crossley, P., Mackay, J., Matthews, J. (2011). Protein-protein interactions: Analysis of a false positive GST pulldown result. Proteins: Structure, Function, and Bioinformatics, 79(8), 2365-2371. [More Information]
  • Gadd, M., Bhati, M., Jeffries, C., Langley, D., Trewhella, J., Guss, M., Matthews, J. (2011). Structural Basis for Partial Redundancy in a Class of Transcription Factors, the LIM Homeodomain Proteins, in Neural Cell Type Specification. Journal of Biological Chemistry, 286(50), 42971-42980. [More Information]
  • Wilkinson-White, L., Gamsjaeger, R., Dastmalchi, S., Wienert, B., Stokes, P., Crossley, M., Mackay, J., Matthews, J. (2011). Structural basis of simultaneous recruitment of the transcriptional regulators LMO2 and FOG1/ZFPM1 by the transcription factor GATA1. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(35), 14443-14448. [More Information]

2010

  • Wilkinson-White, L., Dastmalchi, S., Kwan, A., Ryan, D., Mackay, J., Matthews, J. (2010). (1)H, (15)N and (13)C assignments of an intramolecular Lmo2-LIM2/Ldb1-LID complex. Biomolecular N M R Assignments, 4(2), 203-206. [More Information]
  • Cross, A., Jeffries, C., Trewhella, J., Matthews, J. (2010). LIM Domain Binding Proteins 1 and 2 Have Different Oligomeric States. Journal of Molecular Biology. [More Information]

2009

  • Gadd, M., Langley, D., Guss, M., Matthews, J. (2009). Crystallization and diffraction of an Lhx4-Isl2 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, F65(2), 151-153. [More Information]
  • Matthews, J., Bhati, M., Lehtomaki, E., Mansfield, R., Cubeddu, L., Mackay, J. (2009). It Takes Two to Tango: The Structure and Function of LIM, RING, PHD and MYND Domains. Current Pharmaceutical Design, 15(31), 3681-3969. [More Information]
  • Lowry, J., Gamsjaeger, R., Thong, S., Hung, W., Kwan, A., Broitman-Maduro, G., Matthews, J., Maduro, M., Mackay, J. (2009). Structural analysis of MED-1 reveals unexpected diversity in the mechanism of DNA recognition by GATA-type zinc finger domains. Journal of Biological Chemistry, 284(9), 5827-5835. [More Information]
  • Lowther, J., Robinson, M., Donnelly, S., Xu, W., Stack, C., Matthews, J., Dalton, J. (2009). The Importance of pH in Regulating the Function of the Fasciola hepatica Cathepsin L1 Cysteine Protease. PLoS Neglected Tropical Diseases, 3(1), e369 - 1-e369 - 11. [More Information]

2008

  • Ryan, D., Duncan, J., Lee, C., Kuchel, P., Matthews, J. (2008). Assembly of the oncogenic DNA-binding complex LMO2-Ldb1-TAL1-E12. Proteins: Structure, Function, and Bioinformatics, 70, 1461-1474. [More Information]
  • Pilotelle-Bunner, A., Matthews, J., Cornelius, F., Apell, H., Sebban, P., Clarke, R. (2008). ATP Binding Equilibria of the Na(+),K(+)-ATPase. Biochemistry, 47(49), 13103-13114. [More Information]
  • Matthews, J., Bhati, M., Craig, V., Deane, J., Jeffries, C., Lee, C., Nancarrow, A., Ryan, D., Sunde, M. (2008). Competition between LIM-binding domains. Biochemical Society Transactions, 36(6), 1393-1397. [More Information]
  • Bhati, M., Lee, M., Nancarrow, A., Bach, I., Guss, M., Matthews, J. (2008). Crystallization of an Lhx3-Isl1 complex. Acta Crystallographica Section F: Structural Biology and Crystallization Communications, 64(4), 297-299. [More Information]
  • Matthews, J., Loughlin, F., Mackay, J. (2008). Designed metal-binding sites in biomolecular and bioinorganic interactions. Current Opinion in Structural Biology, 18, 484-490. [More Information]
  • Bhati, M., Lee, C., Nancarrow, A., Lee, M., Craig, V., Bach, I., Guss, M., Mackay, J., Matthews, J. (2008). Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. The EMBO Journal, 27, 2018-2029. [More Information]
  • Gamsjaeger, R., Swanton, M., Kobus, F., Lehtomaki, E., Lowry, J., Kwan, A., Matthews, J., Mackay, J. (2008). Structural and biophysical analysis of the DNA-binding properties of myelin transcription factor 1. Journal of Biological Chemistry, 283(8), 5158-5167. [More Information]

2007

  • Stokes, P., Thompson, L., Marianayagam, N., Matthews, J. (2007). Dimerization of CtIP may stabilize in vivo interactions with the Retinoblastoma-pocket domain. Biochemical and Biophysical Research Communications, 354(1), 197-202. [More Information]
  • Porter, C., Matthews, J., Mackay, J., Pursglove, S., Schmidberger, J., Leedman, P., Pero, S., Krag, D., Wilce, M., Wilce, J. (2007). Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation. B M C Structural Biology, 7(Article number 58), 1-15.
  • Chong, S., Vickaryous, N., Ashe, A., Zamudio, N., Youngson, N., Hemley, S., Stopka, T., Skoultchi, A., Matthews, J., Scott, H., Blewitt, M., et al (2007). Modifiers of epigenetic reprogramming show paternal effects in the mouse. Nature Genetics, 39(5), 614-622. [More Information]
  • Mackay, J., Sunde, M., Lowry, J., Crossley, P., Matthews, J. (2007). Protein interactions: is seeing believing? Trends in Biochemical Sciences, 32(12), 530-531. [More Information]

2006

  • Ely, L., Beddoe, T., Clements, C., Matthews, J., Purcell, A., Kjer-Nielsen, L., McCluskey, J., Rossjohn, J. (2006). Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(17), 6641-6646. [More Information]
  • Ryan, D., Sunde, M., Kwan, A., Marianayagam, N., Nancarrow, A., vanden Hoven, R., Thompson, L., Baca, M., Mackay, J., Visvader, J., Matthews, J. (2006). Identification of the key LMO2-binding determinants on Ldb1. Journal of Molecular Biology. [More Information]
  • Begg, G., Carrington, L., Stokes, P., Matthews, J., Wouters, M., Husain, A., Lorand, L., Iismaa, S., Graham, R. (2006). Mechanism of allosteric regulation of transglutaminase 2 by GTP. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(52), 19683-19688. [More Information]
  • Begg, G., Holman, S., Stokes, P., Matthews, J., Graham, R., Iismaa, S. (2006). Mutation of a critical arginine in the GTP-binding site of transglutaminase 2 disinhibits intracellular cross-linking activity. Journal of Biological Chemistry, 281(18), 12603-12609. [More Information]
  • Jeffries, C., Graham, S., Stokes, P., Collyer, C., Guss, M., Matthews, J. (2006). Stabilization of a binary protein complex by intein-mediated cyclization. Protein Science, 15(11), 2612-2618. [More Information]
  • Kwan, A., Winefield, R., Sunde, M., Matthews, J., Haverkamp, R., Templeton, M., Mackay, J. (2006). Structural basis for rodlet assembly in fungal hydrophobins. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 103(10), 3621-3626. [More Information]

2005

  • Lee, C., Nancarrow, A., Bach, I., Mackay, J., Matthews, J. (2005). 1H, 15N and 13C assignments of an intramolecular Lhx3:ldb1 complex. Journal of Biomolecular NMR, 33(3), 198-198. [More Information]
  • Duggin, I., Matthews, J., Dixon, N., Wake, R., Mackay, J. (2005). A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis. Journal of Biological Chemistry, 280(13), 13105-13113. [More Information]
  • Sharpe, B., Liew, C., Kwan, A., Wilce, J., Crossley, P., Matthews, J., Mackay, J. (2005). Assessment of the robustness of a serendipitous zinc binding fold: mutagenesis and protein grafting. Structure, 13(2), 257-266. [More Information]
  • Ryan, D., Matthews, J. (2005). Protein-protein interactions in human disease. Current Opinion in Structural Biology, 15(4), 441-446. [More Information]
  • Williams, N., Liepinsh, E., Watt, S., Prosselkov, P., Matthews, J., Attard, P., Beck, J., Dixon, N., Otting, G. (2005). Stabilization of native protein fold by intein-mediated covalent cyclization. Journal of Molecular Biology, 346(4), 1095-1108.
  • Liew, C., Simpson, R., Kwan, A., Crofts, L., Loughlin, F., Matthews, J., Crossley, P., Mackay, J. (2005). Zinc fingers as protein recognition motifs: Structural basis for the GATA-1/ Friend of GATA interaction. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 102(3), 583-588. [More Information]

2004

  • Simpson, R., Lee, S., Bartle, N., Sum, E., Visvader, J., Matthews, J., Mackay, J., Crossley, P. (2004). A Classic Zinc Finger From Friend Of Gata Mediates An Interaction With The Coiled-Coil Of Transforming Acidic Coiled-Coil 3. Journal of Biological Chemistry, 279(38), 39789-39797.
  • Marianayagam, N., Sunde, M., Matthews, J. (2004). Biophysical Characterization Of The Interaction Of Ldb1 With Lm02.
  • Dubin, M., Stokes, P., Sum, E., Williams, R., Valova, V., Robinson, P., Lindeman, G., Glover, J., Visvader, J., Matthews, J. (2004). Dimerization Of CtIP, A BRCA1- And CtBP-Interacting Protein, Is Mediated By An N-Terminal Coiled-Coil Motif. Journal of Biological Chemistry, 279(26), 26932-26938.
  • Westman, B., Perdomo, J., Matthews, J., Crossley, P., Mackay, J. (2004). Structural Studies On A Protein-Binding Zinc-Finger Domain Of Eos Reveal Both Similarities And Differences To Classical Zinc Fingers. Biochemistry, 43(42), 13318-13327.
  • Deane, J., Ryan, D., Sunde, M., Maher, M., Guss, M., Visvader, J., Matthews, J. (2004). Tandem Lim Domains Provide Synergistic Binding In The LMO4:Ldb1 Complex. The EMBO Journal, 23(18), 3589-3598.
  • Sunde, M., McGrath, K., Young, L., Matthews, J., Chua, E., Mackay, J., Heather, A. (2004). Tc-1 Is A Novel Tumorigenic And Natively Disordered Protein Associated With Thyroid Cancer. Cancer Research, 64(8), 2766-2773.
  • Marianayagam, N., Sunde, M., Matthews, J. (2004). The Power Of Two: Protein Dimerization In Biology. Trends in Biochemical Sciences, 29(11), 618-625.

2003

  • Simpson, R., Cram, E., Czolij, T., Matthews, J., Crossley, P., Mackay, J. (2003). CCHX zinc finger derivatives retain the ability to bind Zn(II) and mediate protein-DNA interactions. Journal of Biological Chemistry, 278(30), 28011-28018.
  • Deane, J., Maher, M., Langley, D., Graham, S., Visvader, J., Guss, M., Matthews, J. (2003). Crystallization of FLINC4, an intramolecular LM04-ldb1 complex. Acta Crystallographica. Section D: Biological Crystallography, 59(8), 1484-1486.
  • Kwan, A., Gell, D., Verger, A., Crossley, P., Matthews, J., Mackay, J. (2003). Engineering a protein scaffold from a PhD finger. Structure, 11(7), 803-813.
  • Matthews, J., Visvader, J. (2003). LIM-domain-binding protein 1: a multifunctional cofactor that interacts with diverse proteins. EMBO Reports, 4(12), 1132-1137.
  • Deane, J., Mackay, J., Kwan, A., Sum, E., Visvader, J., Matthews, J. (2003). Structural basis for the recognition of Idb1 by the N-terminal LIM domains of LM02 and LM04. The EMBO Journal, 22(9), 2224-2233.
  • Turner, J., Nicholas, H., Bishop, D., Matthews, J., Crossley, P. (2003). The LIM protein FHL3 binds basic Kruppel-like factor/Kruppel-like factor 3 and its co-repressor C-teminal-binding protein 2. Journal of Biological Chemistry, 278(15), 12786-12795.

2002

  • Sharpe, B., Matthews, J., Kwan, A., Newton, A., Gell, D., Crossley, P., Mackay, J. (2002). A new zinc binding fold underlines the versatility of zinc binding modules in protein evolution. Structure, 10(5), 639-648.
  • Kowalski, K., Liew, C., Matthews, J., Gell, D., Crossley, P., Mackay, J. (2002). Characterization of the conserved interaction between GATA and FOG family proteins. Journal of Biological Chemistry, 277(38), 35720-35729.
  • Deane, J., Visvader, J., Mackay, J., Matthews, J. (2002). Letter to the Editor: 1H, 15N and 13C assignments of FLIN4, an intramolecular LMO4:ldb1 complex. Journal of Biomolecular NMR, 23(2), 165-166.
  • Warton, K., Tonini, R., Fairlie, W., Matthews, J., Valenzuela, S., Qiu, M., Wu, W., Pankhurst, S., Bauskin, A., Harrop, S., et al (2002). Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in chinese hamster ovary cells expressing CLIC1. Journal of Biological Chemistry, 277(29), 26003-26011.
  • Matthews, J., Sunde, M. (2002). Zinc fingers- folds for many occasions. IUBMB Life, 54(6), 351-355.

2001

  • Deane, J., Sum, E., Mackay, J., Lindeman, G., Visvader, J., Matthews, J. (2001). Design, production and characterization of FLIN2 and FLIN4: the engineering of intramolecular ldb1: LMO complexes. Protein Engineering, 14, 493-499.
  • Matthews, J., Visvader, J., Mackay, J. (2001). Letter to the Editor: 1H, 15N and 13C assignments of FLIN2, an intramolecular LMO2:ldb1 complex. Journal of Biomolecular NMR, 21(4), 385-386.
  • Mackay, J., Matthews, J., Winefield, R., Mackay, L., Haverkamp, R., Templeton, M. (2001). The hydrophobin EAS is largely unstructured in solution and functions by forming amyloid-like structures. Structure, 9, 83-91.

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