student profile: Ms Laura Jowett


Thesis work

Thesis title: Exploring Selective Anion Transport in Novel and Existing Small Molecules

Supervisors: Philip GALE , Katrina JOLLIFFE

Thesis abstract:

Firstly, a novel series of chloride transporters based on the new class of compounds 'perenosins' were tested for chloride anion binding and transport properties. Thier chloride selective anion transport properties were tested and it was found that protonation was required for efficient transport and therefore removing any selectivity for chloride.
Secondly, the transport properties of an exisiting series of compounds were revisited after some newly developed anion uniport assays showed that earlier transport efficieinces had been vastly underestimated.

Note: This profile is for a student at the University of Sydney. Views presented here are not necessarily those of the University.