student profile: Miss Letitia Sng


Thesis work

Thesis title: Methodological considerations for evaluation of eQTL mapping studies: application to the human brain

Supervisors: Peter THOMSON , Daniah TRABZUNI

Thesis abstract:

Expression quantitative trait loci (eQTL) mapping represents the combination of two modern genomics technologies: high-density marker arrays and expression arrays. eQTL mapping allows important biological pathways to be identified. It is a highly computationally intensive procedure, and this project will focus on developing efficient and robust statistical methodologies to undertake this. The work will be done with application to the human brain, but will be applicable to other tissues and organisms.

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