Dr Murray Thomson

A08 - Heydon-Laurence Building
The University of Sydney

Telephone +61 2 9036 6412
Fax +61 2 9351 4771

Website Room 314, A08 - Heydon-Laurence Building
Publication list via Research Gate

Research interests

Cellular and Molecular Biology

I am fascinated as to how cells and organelles communicate with each other in order to function in homeostasis and coordinate functions during growth and development. I am also interested in the use of cellular and molecular techniques in biotechnology. In the past I have discovered new cardiostimulants in sea anemones, studied the effects of nutrition on cell signaling systems in sheep skin and found novel proteins that may be regulating steroid hormone production and development in the human placenta. At present I am working on determining how protein kinase anchoring proteins (AKAPs) and G proteins modulate mitochondrial physiology and I am collaborating on a project to identify allergens in fungi. Educational Research I am keen to continue research aimed at increasing the depth of learning through techniques such as motivation and the use of multimedia. I am also interested in the effects of curriculum development in competency and capability based education.

Educational Research

I am keen to continue research aimed at increasing the depth of learning through techniques such as motivation and the use of multimedia. I am also interested in the effects of curriculum development in competency and capability based education.

Current projects

Honours Projects

Heat Shock Proteins as Indicators of Stress in Echinoderms

Supervisors: Maria Byrne (Anatomy and Histology), Murray Thomson.

Many newly expressed cellular proteins need a little help to fold into their correct 3 dimensional structure and they are given this help by specialized proteins that are referred to as molecular chaperones. Heat shock proteins are a major family of molecular chaperones and these proteins were discovered for their ability to help reform the high levels of incorrectly folded proteins that are produced by elevated temperatures.

This kind of stress is pertinent to organisms that live in marine environments with widely fluctuating temperatures and of increasing interest in the face of climate change. This presents an exciting opportunity to work in the field and the lab in studying the cellular effects of environmental stress on marine creatures such as sea urchins and sea stars (an adult and juvenile of each shown below) and you can work in both Maria's, and my lab.

For more honours project opportunities in Behaviour, Physiology and Ecology click here.

Echinoderms banner

Behaviour, Physiology and Ecology Lab

This is a large and modern shared lab space utilised by academics, postdocs, PhD and honours students and other researchers. Equipment includes a cryostat to cut thin sections of tissue, electrophoresis gear for nucleic acid and protein studies and digital microscopes that can record with stills and video.

Ecology Lab Banner

Selected grants

2007

  • Effect of deep-sea drilling on sustainability of deep-sea ecosystems; Pile A, Pattiaratchi C, Booth D, Thomson M, Darley B, Pattiaratchi C, Booth D, Skropeta D, Jarvis S, Skropeta D; Australian Research Council (ARC)/Linkage Projects (LP).

2005

  • Molecular and cellular pathways that have evolved to regulate uterine function in a viviparous lizard; Thomson M, Thompson M; University of Sydney/Research & Development.

2004

  • The role of the developmental gene HOXA10 in the regulation of the uterus in a vivaparous lizard; Thompson M, Thomson M, Murphy C; DVC Research/Research and Development Scheme: Research and Development (R&D).

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Tentori, E., Thomson, M. (2008). Differential Expression of Soluble and Membrane-bound Proteins in Soft Corals (Cnidaria: Octocorallia). In Bernhard M. Riegl, R. E. Dodge (Eds.), 11th International Coral Reef Symposium: Fort Lauderdale, Florida, USA, July 7-11, 2008, (pp. 154-158). Dania Beach, Florida: National Coral Reef Institute.

Journals

  • Thomson, M. (2014). Ovoviviparous reproduction in the intertidal isopod Cirolana harfordi. Invertebrate Reproduction and Development.
  • Thomson, M. (2013). Mouthparts and their setae of the intertidal isopod Cirolana harfordi. Journal of Microscopy, 252(2), 111-121. [More Information]
  • Thomson, M. (2013). The physiological roles of placental corticotropin releasing hormone in pregnancy and childbirth. Journal of Physiology and Biochemistry, 69(3), 559-573. [More Information]
  • Ma, M., Thomson, M. (2012). Protein kinase A subunit alpha catalytic and A kinase anchoring protein 79 in human placental mitochondria. The Open Biochemistry Journal, 6, 23-30.
  • Zivanovic, A., Pastro, N., Fromont, J., Thomson, M., Skropeta, D. (2011). Kinase Inhibitory, Haemolytic and cytotoxic activity of three deep-water sponges from North Western Australia and their fatty acid composition. Natural Product Communications: an international journal for communications and reviews, 6(12), 1921-1924.
  • Thomson, M. (2010). Challenges and Achievements in Developing Competencies in Digital Microscopy. Synergy, (30), 57-60.
  • Thomson, M. (2010). Mouthparts of the deep-sea isopod Bathynomus pelor (Isopoda, Cirolanidae). Crustaceana, 83(12), 1483-1506. [More Information]
  • Thomson, M. (2010). Signal Transduction of Steroidogenic Hormones to the Adrenal and Gonadal Mitochondria and the Possibilities for Combating Lipoid Congenital Adrenal Hyperplasia. Current Signal Transduction Therapy, 5(2), 161-169. [More Information]
  • Thomson, M., Robertson, K., Pile, A. (2009). Microscopic structure of the antennulae and antennae on the deep-sea isopod Bathynomus pelor. Journal of Crustacean Biology, 29(3), 302-316.
  • Thomson, M. (2008). The Effects of Placental Corticotrophin Releasing Hormone on the Physiology and Psychology of the Pregnant Woman. Current Women's Health Reviews, 4(4), 270-279.
  • Thomson, M., Herbert, J., Thompson, M. (2006). Tyrosine phosphorylated proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, 144(3), 382-386. [More Information]
  • Thomson, M., Herbert, J., Murphy, C., Thompson, M. (2005). HoxA10-like proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, 142(1), 123-127. [More Information]
  • Thomson, M. (2003). Does cholesterol use the mitochondrial contact site as a conduit to the steroidgenic pathway? BioEssays, 25(3), 252-258. [More Information]
  • Thomson, M., McCarroll, J., Bond, J., Gordon-Thomson, C., Williams, E., Moore, G. (2003). Parathyroid hormone-related peptide modules signal pathways in skin and hair follicle cells. Experimental Dermatology, 12(4), 389-395.
  • Thomson, M. (2002). Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria. Cellular and Molecular Life Sciences, 59(2), 213-219. [More Information]
  • Kuyznierewicz, I., Thomson, M. (2002). GTP-binding proteins Gsalpha, Gialpha, and RAN identified in mitochondria of human placenta. Cell Biology International, 26(1), 99-108. [More Information]
  • Phillips, P., Thomson, M. (2002). Small GTP-binding proteins in the nuclei of human placenta. Journal Of Cellular Biochemistry, 84(1), 100-107.
  • Thomson, M. (2002). The regulation of mitochondrial physiology by organelle-associated GTP-binding proteins. Cell Biochemistry And Function, 20(4), 273-278. [More Information]
  • Thomson, M., Corso, M. (2001). Protein Phosphorylation in Mitochondria from Human Placenta. Placenta, 22, 432-439.

Conferences

  • Nguyen, H., Byrne, M., Thomson, M. (2013). Hsp70 expression in the south-eastern Australian sea urchins Heliocidaris erythrogramma and H. tuberculata. Echinoderms in a Changing World: 13th International Echinoderm Conference, Leiden, The Netherlands: CRC Press/Balkema. [More Information]
  • Thomson, M. (2013). Is the intertidal isopod Cirolana harfordi a filter feeder and social animal? Proceedings of the Australian Marine Sciences Association meeting, Adelaide, Australia: AMSA.
  • Thomson, M., Stoddart, H., Smith, H. (2009). Crustacean communities living around oil rigs. Proceedings of the Australian Marine Sciences Association meeting, Adelaide, Australia: AMSA.
  • Holmes, S., Pile, A., Thomson, M., Elstub, H. (2009). Modes of reproduction, population genetics and dispersal: what connects what? AMSA2009 - Marine Connectivity, Adelaide, South Australia: ALMSA.

2014

  • Thomson, M. (2014). Ovoviviparous reproduction in the intertidal isopod Cirolana harfordi. Invertebrate Reproduction and Development.

2013

  • Nguyen, H., Byrne, M., Thomson, M. (2013). Hsp70 expression in the south-eastern Australian sea urchins Heliocidaris erythrogramma and H. tuberculata. Echinoderms in a Changing World: 13th International Echinoderm Conference, Leiden, The Netherlands: CRC Press/Balkema. [More Information]
  • Thomson, M. (2013). Is the intertidal isopod Cirolana harfordi a filter feeder and social animal? Proceedings of the Australian Marine Sciences Association meeting, Adelaide, Australia: AMSA.
  • Thomson, M. (2013). Mouthparts and their setae of the intertidal isopod Cirolana harfordi. Journal of Microscopy, 252(2), 111-121. [More Information]
  • Thomson, M. (2013). The physiological roles of placental corticotropin releasing hormone in pregnancy and childbirth. Journal of Physiology and Biochemistry, 69(3), 559-573. [More Information]

2012

  • Ma, M., Thomson, M. (2012). Protein kinase A subunit alpha catalytic and A kinase anchoring protein 79 in human placental mitochondria. The Open Biochemistry Journal, 6, 23-30.

2011

  • Zivanovic, A., Pastro, N., Fromont, J., Thomson, M., Skropeta, D. (2011). Kinase Inhibitory, Haemolytic and cytotoxic activity of three deep-water sponges from North Western Australia and their fatty acid composition. Natural Product Communications: an international journal for communications and reviews, 6(12), 1921-1924.

2010

  • Thomson, M. (2010). Challenges and Achievements in Developing Competencies in Digital Microscopy. Synergy, (30), 57-60.
  • Thomson, M. (2010). Mouthparts of the deep-sea isopod Bathynomus pelor (Isopoda, Cirolanidae). Crustaceana, 83(12), 1483-1506. [More Information]
  • Thomson, M. (2010). Signal Transduction of Steroidogenic Hormones to the Adrenal and Gonadal Mitochondria and the Possibilities for Combating Lipoid Congenital Adrenal Hyperplasia. Current Signal Transduction Therapy, 5(2), 161-169. [More Information]

2009

  • Thomson, M., Stoddart, H., Smith, H. (2009). Crustacean communities living around oil rigs. Proceedings of the Australian Marine Sciences Association meeting, Adelaide, Australia: AMSA.
  • Thomson, M., Robertson, K., Pile, A. (2009). Microscopic structure of the antennulae and antennae on the deep-sea isopod Bathynomus pelor. Journal of Crustacean Biology, 29(3), 302-316.
  • Holmes, S., Pile, A., Thomson, M., Elstub, H. (2009). Modes of reproduction, population genetics and dispersal: what connects what? AMSA2009 - Marine Connectivity, Adelaide, South Australia: ALMSA.

2008

  • Tentori, E., Thomson, M. (2008). Differential Expression of Soluble and Membrane-bound Proteins in Soft Corals (Cnidaria: Octocorallia). In Bernhard M. Riegl, R. E. Dodge (Eds.), 11th International Coral Reef Symposium: Fort Lauderdale, Florida, USA, July 7-11, 2008, (pp. 154-158). Dania Beach, Florida: National Coral Reef Institute.
  • Thomson, M. (2008). The Effects of Placental Corticotrophin Releasing Hormone on the Physiology and Psychology of the Pregnant Woman. Current Women's Health Reviews, 4(4), 270-279.

2006

  • Thomson, M., Herbert, J., Thompson, M. (2006). Tyrosine phosphorylated proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, 144(3), 382-386. [More Information]

2005

  • Thomson, M., Herbert, J., Murphy, C., Thompson, M. (2005). HoxA10-like proteins in the reproductive tract of the viviparous lizard Eulamprus tympanum and the oviparous lizard Lampropholis guichenoti. Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, 142(1), 123-127. [More Information]

2003

  • Thomson, M. (2003). Does cholesterol use the mitochondrial contact site as a conduit to the steroidgenic pathway? BioEssays, 25(3), 252-258. [More Information]
  • Thomson, M., McCarroll, J., Bond, J., Gordon-Thomson, C., Williams, E., Moore, G. (2003). Parathyroid hormone-related peptide modules signal pathways in skin and hair follicle cells. Experimental Dermatology, 12(4), 389-395.

2002

  • Thomson, M. (2002). Evidence of undiscovered cell regulatory mechanisms: phosphoproteins and protein kinases in mitochondria. Cellular and Molecular Life Sciences, 59(2), 213-219. [More Information]
  • Kuyznierewicz, I., Thomson, M. (2002). GTP-binding proteins Gsalpha, Gialpha, and RAN identified in mitochondria of human placenta. Cell Biology International, 26(1), 99-108. [More Information]
  • Phillips, P., Thomson, M. (2002). Small GTP-binding proteins in the nuclei of human placenta. Journal Of Cellular Biochemistry, 84(1), 100-107.
  • Thomson, M. (2002). The regulation of mitochondrial physiology by organelle-associated GTP-binding proteins. Cell Biochemistry And Function, 20(4), 273-278. [More Information]

2001

  • Thomson, M., Corso, M. (2001). Protein Phosphorylation in Mitochondria from Human Placenta. Placenta, 22, 432-439.

To update your profile click here. For support on your academic profile contact Research Support.