Dr Santosh Rudrawar

B Pharm, M S (Pharm), PhD NIPER
ARC DECRA Fellow

F11 - Chemistry Building
The University of Sydney

Telephone 61 2 9114 1190
Fax 61 2 9351 3329

Curriculum vitae Curriculum vitae

Biographical details

  • BPharm, Amravati University, India 1999
  • MS (Pharm), National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India 2000
  • PhD National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar, India 2008
  • ARC Post-doctoral research associate, Institute for Glycomics, Griffith University 2008-2012
  • NHMRC Post-doctoral research associate, The University of Sydney 2013
  • ARC Discovery Early Career Research Fellow, The University of Sydney 2014-present

Research interests

My research is focused on the development of chemical tools to study carbohydrate-processing enzymes.

  • Synthesis of glycopeptides, glycoconjugates as bisubstrate enzyme inhibitor probes
  • Development of glycolipid-based vaccine adjuvants
  • Anti-infective drug discovery
  • Bioorganic medicinal chemistry

Selected grants

2014

  • University of Sydney Automated Peptide Synthesis Platform; Payne R, Britton W, Byrne S, Chan H, Clarke R, Hunt N, Jolliffe K, Kassiou M, Lay P, Mackay J, Matthews J, McErlean C, New E, Rasmussen H, Rendina L, Rudrawar S, Rutledge P, Shepherd N; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Development of Innovative Chemical Tools for Studying Glycosyltransferases; Rudrawar S; Australian Research Council (ARC)/Discovery Early Career Researcher Award (DECRA).

Selected publications

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Journals

  • Rudrawar, S., Pascolutti, M., Bhatt, B., Thomson, R., Itzstein, M. (2013). An efficient synthesis of C3 C-alkylated Neu5Ac2en derivatives. Tetrahedron Letters, 54(10), 1198-1201. [More Information]
  • Rudrawar, S., Dyason, J., Maggioni, A., Thomson, R., Itzstein, M. (2013). Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidas 150-loop. Bioorganic and Medicinal Chemistry, 21(16), 4820-4830. [More Information]
  • Sarkar, A., Roy, S., Kumar, D., Madaan, C., Rudrawar, S., Chakraborti, A. (2012). Lack of correlation between catalytic efficiency and basicity of amines during the reaction of aryl methyl ketones with DMF-DMA: an unprecedented supramolecular domino catalysis. Organic and Biomolecular Chemistry, 10(2), 281-286. [More Information]
  • Rudrawar, S., Kerry, P., Rameix-Welti, M., Maggioni, A., Dyason, J., Rose, F., van der Werf, S., Thomson, R., Naffakh, N., Russell, R., et al (2012). Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility. Organic and Biomolecular Chemistry, 10(43), 8628-8639. [More Information]
  • Rudrawar, S., Dyason, J., Rameix-Welti, M., Rose, F., Kerry, P., Russell, R., van der Werf, S., Thomson, R., Naffakh, N., Itzstein, M. (2010). Novel sialic acid derivative lock open the 150-loop of an influenza A virus group-1 sialidase. Nature Communications, 1(113), 1-7. [More Information]
  • Kumar, D., Rudrawar, S., Chakraborti, A. (2008). One-pot synthesis of 2-substituted benzoxazoles directly from carboxylic acids. Australian Journal of Chemistry: an international journal for chemical science, 61(11), 881-887. [More Information]
  • Chakraborti, A., Rudrawar, S., Jadhav, K., Kaur, G., Chankeshwara, S. (2007). "On water" organic synthesis: a highly efficient and clean synthesis of 2-aryl/heteroaryl/styryl benzothiazoles and 2-alkyl/aryl alkyl benzothiazolines. Green Chemistry, 9(12), 1335-1340. [More Information]

Conferences

  • Rudrawar, S. (2011). Sialic acid derivatives targeting the open '150-loop' form of group-1 influenza A virus sialidases. 16th EUROCARB-European Carbohydrate Symposium, Oral presentation: July 2011.

Patents

  • Chakraborti, A., Kumar, D., Rudrawar, S., Bindal, S., Chopra, P. (2012). Indian Pat. Appl. Patent No. 3245/DEL2012. India.
  • Itzstein, M., Dyason, J., Thomson, R., Rudrawar, S., Pascolutti, M. (2011). PCT Int. Appl. Patent No. WO2011006208.
  • Chakraborti, A., Sarin, S., Rudrawar, S., Kumar, R., Chankeshwara, S., Ray, A., Dastidar, S. (2008). United States Patent. Patent No. 20080207659.
  • Chakraborti, A., Sarin, S., Rudrawar, S., Kumar, R., Chankeshwara, S., Ray, A., Dastidar, S. (2008). Eur. Pat. Appl. India.

2013

  • Rudrawar, S., Pascolutti, M., Bhatt, B., Thomson, R., Itzstein, M. (2013). An efficient synthesis of C3 C-alkylated Neu5Ac2en derivatives. Tetrahedron Letters, 54(10), 1198-1201. [More Information]
  • Rudrawar, S., Dyason, J., Maggioni, A., Thomson, R., Itzstein, M. (2013). Novel 3,4-disubstituted-Neu5Ac2en derivatives as probes to investigate flexibility of the influenza virus sialidas 150-loop. Bioorganic and Medicinal Chemistry, 21(16), 4820-4830. [More Information]

2012

  • Chakraborti, A., Kumar, D., Rudrawar, S., Bindal, S., Chopra, P. (2012). Indian Pat. Appl. Patent No. 3245/DEL2012. India.
  • Sarkar, A., Roy, S., Kumar, D., Madaan, C., Rudrawar, S., Chakraborti, A. (2012). Lack of correlation between catalytic efficiency and basicity of amines during the reaction of aryl methyl ketones with DMF-DMA: an unprecedented supramolecular domino catalysis. Organic and Biomolecular Chemistry, 10(2), 281-286. [More Information]
  • Rudrawar, S., Kerry, P., Rameix-Welti, M., Maggioni, A., Dyason, J., Rose, F., van der Werf, S., Thomson, R., Naffakh, N., Russell, R., et al (2012). Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility. Organic and Biomolecular Chemistry, 10(43), 8628-8639. [More Information]

2011

  • Itzstein, M., Dyason, J., Thomson, R., Rudrawar, S., Pascolutti, M. (2011). PCT Int. Appl. Patent No. WO2011006208.
  • Rudrawar, S. (2011). Sialic acid derivatives targeting the open '150-loop' form of group-1 influenza A virus sialidases. 16th EUROCARB-European Carbohydrate Symposium, Oral presentation: July 2011.

2010

  • Rudrawar, S., Dyason, J., Rameix-Welti, M., Rose, F., Kerry, P., Russell, R., van der Werf, S., Thomson, R., Naffakh, N., Itzstein, M. (2010). Novel sialic acid derivative lock open the 150-loop of an influenza A virus group-1 sialidase. Nature Communications, 1(113), 1-7. [More Information]

2008

  • Chakraborti, A., Sarin, S., Rudrawar, S., Kumar, R., Chankeshwara, S., Ray, A., Dastidar, S. (2008). United States Patent. Patent No. 20080207659.
  • Kumar, D., Rudrawar, S., Chakraborti, A. (2008). One-pot synthesis of 2-substituted benzoxazoles directly from carboxylic acids. Australian Journal of Chemistry: an international journal for chemical science, 61(11), 881-887. [More Information]
  • Chakraborti, A., Sarin, S., Rudrawar, S., Kumar, R., Chankeshwara, S., Ray, A., Dastidar, S. (2008). Eur. Pat. Appl. India.

2007

  • Chakraborti, A., Rudrawar, S., Jadhav, K., Kaur, G., Chankeshwara, S. (2007). "On water" organic synthesis: a highly efficient and clean synthesis of 2-aryl/heteroaryl/styryl benzothiazoles and 2-alkyl/aryl alkyl benzothiazolines. Green Chemistry, 9(12), 1335-1340. [More Information]

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