Professor Tony Weiss

PhD FRSC FRSA FAIMBE FAICD MRACI CChem
Professor of Biochemistry and Molecular Biotechnology

D17 - Charles Perkins Centre
The University of Sydney

Telephone +61 2 9351 3464
Fax +61 2 9351 5858

Biographical details

I am Professor of Biochemistry & Molecular Biotechnology at the University of Sydney, Professor at the Bosch Institute, Professor at the Charles Perkins Centre, Professor at the Royal Prince Alfred Hospital (Honorary) and biotech company founder. I was Chair SMB Proteomics and Biotechnology at the University of Sydney where I was also Foundation Chair of Molecular Biotechnology. Awards include FRSC, FRSA, FAIMBE, FAICD, Fulbright Scholar, Roslyn Flora Goulston Prize, NIH Fogarty International Fellow, Thomas and Ethel Mary Ewing Scholar, Australian Academy of Science and Royal Society Exchange Scholar, David Syme Research Medal, Amersham Pharmacia Biotechnology Medal, NSW Commercialization Expo Prize, Australian Innovation Challenge Award, Sir Zelman Cowen Exchange Fellow, Fondation des Treilles Scholar, Pauling Prize Medal, Barry Preston Award, Australasian Society for Biomaterials and Tissue Engineering Research Excellence Award, FAOBMB Entrepreneurship Award. National appointments include the Australian Biotechnology Advisory Council, National Enabling Technology Strategy Advisory Council, and Biological Sciences and Biotechnology, Australian Research Council College of Experts where I was national Chair. I am an inventor with twenty-five awarded international patents. I am on the Editorial Boards of Biomacromolecules, Biomaterials, Biomedical Materials, BioNanoScience and Tissue Engineering.

Current collaborative grants include Australian Research Council (ARC; 3), National Health & Medical Research Council (NHMRC; 2), National Institutes of Health USA (NIH; 2) encompassing Tufts University, Harvard University and MIT.

The Weiss Laboratory at the University of Sydney is the leading research site for tropoelastin and synthetic elastin biomaterials. My laboratory is funded through a combination of many international and national collaborative research grants and enjoys the contributions of a fine team of competitively placed postdocs, postgraduate students and technical staff.

Specialties:elastin, tropoelastin, extracellular matrix, tissue engineering, wound repair, cardiovascular repair, biochemistry, molecular biotechnology, research

Research interests

For updated information please go to sydney.edu.au/science/people/tony.weiss.php .

The Weiss Lab's research focuses on the assembly of human elastic tissue, damage and its repair. We are very interested in the amazing, self-assembling elastic protein tropoelastin and the use of synthetic elastin to repair elastic tissues in skin, artery, bladder and lung.

Keywords

Biochemistry; Cardiovascular diseases; Cell biology

Selected grants

2014

  • Technion Israel Institute of Technology (Technion IIT) - Sydney University - 3D Tissue Regeneration; Weiss A; Technion Society of Australia (Victoria)/Research Support.
  • Tissue Engineered Synthetic Vascular Grafts for Arterial Replacement; Ng M, Weiss A, Bilek M; National Health and Medical Research Council (NHMRC)/Development Grants.
  • La Vision BioTec Ultramicroscope; Murphy C, Braet F, Byrne M, Chan-Ling T, Fraser S, Goldsbury C, Halliday G, Hambly B, Johnstone D, Keay K, Lovelace M, Lyons G, Mason R, Overall R, Owens T, Richardson D, Stone J, Weiss A; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Bioengineering Synthetic Elastin Conduits for Arterial Revascularisation; Ng M, Weiss A, Bannon P; National Health and Medical Research Council (NHMRC)/Project Grants.
  • (CTM CRC) CRC Cell Therapy Manufacturing Project 1-02 Surface Engineering of MulitStem (MAPC) polymer patch for the treatment of diabetic foot ulcers; Bilek M, Weiss A, McKenzie D; Cell Therapy Manufacturing Cooperative Research Centre (CRC)/Project.

2013

  • (CTM CRC) CRC Cell Therapy Manufacturing Project 1.01 Improving Cell Yields from Hollow Fiber Bioreactor Systems; Kinzie M, Whittle J, Bilek M, Weiss A, McKenzie D; Cell Therapy Manufacturing Cooperative Research Centre (CRC)/Project.
  • ATVRE - Assistive Technologies for Virtual Rehabilitation Engineering; Feng D, Dehghani F, Dunstan C, Jin C, Kim J, Li Q, McEwan A, Ruys A, Brooker G, Buckley T, Cai T, Davis G, Fornusek C, Fulham M, Khadra M, Mohamed A, Murray G, Peck C, Vucetic B, Weiss A; DVC Research/Research Network Scheme (SyReNS).
  • Biomaterials with multifaceted tunability and bio-specificity; Bilek M, Weiss A, Bao B; Australian Research Council (ARC)/Discovery Projects (DP).
  • Wide field super-resolution microscopy with ground state depletion - Exploring nanoscopic life in chronic diseases; Braet F, Weiss A, King N, Dos Remedios C, Traini D, Graeber M, Murphy C, Grau G, Soon L, Newsome T, Goldsbury C, Lovelace M, Gorrell M, Pollock C; DVC Research/Equipment Grant.
  • An automated 3D electron microscopy imaging system comprising a 3View2 and field-emission scanning electron microscope; Liu Z, Chen M, Copeland L, Crawford J, Langrish T, Li Q, Mai Y, Overall R, Weiss A, Ye L; DVC Research/Equipment Grant.
  • The Nanotemper: State-of-the-art instrumentation for the characterization of protein interactions; Payne R, Matthews J, Ataide S, Campbell I, Weiss A, Sunde M, Mackay J; Clive and Vera Ramaciotti Foundations/Awards for Biomedical Research: Major Equipment.

2012

  • Multifunctional Tropoelastin-Silk Biomaterial Systems; Kaplan D, Weiss A; National Institutes of Health (USA)/Research Support.
  • Development of Endovascular Stents with Proactive Biocompatibility; Ng M, Weiss A, Bilek M; National Health and Medical Research Council (NHMRC)/Development Grants.
  • Bioengineering Endovascular Prostheses with Proactive Biocompatibility; Ng M, Weiss A, Bilek M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Novel treatment of damaged airway; Weiss A; Rebecca L Cooper Medical Research Foundation/Equipment Grant.
  • Versatile elastin based hybrid hydrogels for chondrocyte transplantation and repair; Weiss A, Dehghani F; Australian Research Council (ARC)/Discovery Projects (DP).

2011

  • Multifunctional surfaces for implantable biomedical devices (Cochlear Limited, LfC Sp. z o.o., Spinecell Pty Ltd) - Multifuntional surfaces for implantable biomedical devices; Bilek M, Weiss A, McKenzie D; Australian Research Council (ARC)/Linkage Projects (LP).
  • Scalable Units for Building Vascularized Cardiac Grafts; Weiss A; National Institutes of Health (USA)/Research Support.
  • The Instron testing material instrument (Model 5943); Dehghani F, Weiss A, Bilek M, Zreiqat H, Dunstan C, Chrzanowski W, Rohanizadeh R; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2010

  • Tropoelastin: functional analysis of the cell interactive domain; Weiss A; Australian Research Council (ARC)/Discovery Projects (DP).
  • Elastaderm: an improved human skin substitute for treating burns; Weiss A, Kimble R; National Health and Medical Research Council (NHMRC)/Development Grants.
  • A Unique Soft Matter High-Performance Scanning Probe Microscopy (HP-SPM) Facility; Thordarson P, Neto C, Warr G, Coster H, Weiss A, Perrier S, Hawkett B, Bilek M, Sunde M, Harris A; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • A 5-D Correlative Imaging Platform: Combining the Strengths of Light and Electron Microscopy; Braet F, Mitchell H, Soon L, Overall R, Day D, Waterhouse P, Marc J, Conigrave A, Weiss A, Newsome T, Meikle S, Goetz J, Goldsbury C, Hambley T, Ramzan I, Young P, Traini D, Grewal T, Fleming S, Murphy C, Grau G, Weninger W, Dos Remedios C, Wimmer-Kleikamp S, Munroe P, Stevens-Kalceff M, Foster L, Killingsworth M; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2009

  • Skin Repair: Tissue Engineering using Synthetic Human Elastin; Weiss A; Australian Institute of Nuclear Science and Engineering (AINSE)/Awards.
  • Applied Biosystems 7500 Fast Real Time PCR system; Campbell I, Crossley P, Brand-Miller J, Caterson I, Hall R, Weiss A, Conigrave A, Mackay J, Matthews J, Sunde M, Gell D, Bell-Anderson K, Nicholas H, Crossett B; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2008

  • Elastagen; Weiss A, Hawthorn H, Daniels R; Elastagen/Research Grant.
  • Plasma processes for optimising the performance of surfaces for biomedical applications; Bilek M, Diwan A, Patrick J, Storey D, Weiss A, McKenzie D; Australian Research Council (ARC)/Linkage Projects (LP).
  • Elatin-based vascular grafts; Weiss A, Ng M, Edwards G; Heart Foundation of Australia/Grants-in-Aid.
  • High-Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at the Nanometre-Level; Cairney J, Ringer S, Braet F, Ferry M, Sorrell C, Ye L, Ruys A, Barton G, Harris A, Ranzi G, Eggleton B, Grillet C, Mckenzie D, Lay P, Masters A, Parker A, Overall R, Weiss A, Murphy C, Ramzan I, Copeland L, Potts D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • High Resolution Field Emission Scanning Electron Microscopy (FESEM) Platform for Characterisation at; Ringer S, Barton G, Ramzan I, Copeland L, Potts D, Braet F, Grillet C, Lay P, Murphy C, Cairney J, Ferry M, Eggleton B, McKenzie D, Masters A, Parker A, Overall R, Weiss A, Ruys A, Sorrell C, Ye L, Harris A, Ranzi G; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2007

  • State of the art high resolution thermal analysis suite for the life and material sciences; Stewart P, Young P, Traini D, Chan K, Murray M, Dehghani F, Hibbs D, Larson I, Warr G, Weiss A; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Precision Titration/ Solution Calorimeter accessory for the Tam III Iosthermal calorimeter Calorimet; Chan K, Murray M, Hibbs D, Young P, Traini D, Weiss A, Stewart P; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • High-resolution electron tomographic facility for nanoanlytical characterization in the material an; Braet F, Ramzan I, Ringer S, Soon L, Liu Z, Hambley T, Lay P, Warr G, Thordarson P, Murphy C, Dos Remedios C, Weiss A, Parker A; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Total internal reflectance fluorescence microscope (TIRFM); Soon L, Rendina L, Braet F, Weiss A, Grau G, Lyons G; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Biochemistry of tropoelastin and elastin: the molecular architecture of elastic fibre assembly; Weiss A, Kielty C; Australian Research Council (ARC)/Discovery Projects (DP).

2006

  • 3449 Investigation Of The Formation Of Synthetic Elastin Surfaces Using X-Ray And Neutron Reflectometry; Weiss A; Australian Institute of Nuclear Science and Engineering (AINSE)/Awards.
  • 3410 Saxs Of Mutant Human Tropoelastin; Weiss A; Australian Institute of Nuclear Science and Engineering (AINSE)/Awards.

2005

  • Elastagen Pty Ltd: DSRD top up for BIF Project; Weiss A.
  • Smart bomb technology to restrict cancer cell growth; Weiss A; University of Sydney/Cancer Research Fund.
  • Biomaterial applications of synthetic elastin; Weiss A, Langer R; Australian Research Council (ARC)/Linkage International: ARC International Fellowships (ARCIF).
  • Electrospinning nano-diameter fibres using human proteins; Weiss A; University of Sydney/Research & Development.
  • Production & purification of tropoelastin using optimized processes, formulation studies, in vitro cell work examining the best formulations for cell attachment and growth and in vivo studies examining material tolerance, cell invasion and incorporation; Weiss A; Elastagen Pty Ltd/Research Grant.

2003

  • Biochemistry of tropoelastin and elastin; Weiss A; Australian Research Council (ARC)/Discovery Projects (DP).

2002

  • Candidate molecular markers for Hutchinson- Gilford Progeria Syndrome; Weiss A; Progeria Research Foundation (USA)/Research Grant.
  • Tropoelastin research project; Weiss A, Jazwinska L, Trotter P; Johnson and Johnson Wound Management (USA)/BLO Project.

2001

  • Spectroscopy studies of human elastin proteins; Weiss A; Ronald Geoffrey Arnott Foundation (Perpetual)/Research Grant.

2000

  • Tropoelastin research; Farrell L, Spencer P, Dyer S, Bohdanowicz T, Weiss A; Johnson and Johnson Research Pty Ltd/Research Support.
  • Engineering super-zippers of Jun and Fos: a novel anti-cancer strategy; Weiss A, Easterbrook-Smith S; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Biochemistry of tropoelastin; Weiss A; Australian Research Council (ARC)/Large Research Grants (LRG).

1999

  • Synthesis of human elastin; Weiss A, Spencer P; Australian Research Council (ARC)/Strategic Partnerships with Industry - Research and Training (SPIRT).

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Rnjak-Kovacina, J., Weiss, A. (2013). The Role of Elastin in Wound Healing and Dermal Substitute Design. In Lars-Peter Kamolz, David Benjamin Lumenta (Eds.), Dermal Replacements in General, Burn, and Plastic Surgery: Tissue Engineering in Clinical Practice, (pp. 57-66). Vienna, Austria: Springer-Verlag.
  • Nivison-Smith, L., Weiss, A. (2011). Elastin Based Constructs. In Daniel Eberli (Eds.), Regenerative Medicine and Tissue Engineering - Cells and Biomaterials, (pp. 323-340). Rijeka, Croatia: InTech Publishers.
  • Rnjak-Kovacina, J., Daamen, W., Pierna, M., Rodriguez-Cabello, J., Weiss, A. (2011). Elastin Biopolymers. In Ducheyne, P; Healy, K.E; Hutmacher, D.W; Grainger, D; Kirkpatrick, C.J (Eds.), Comprehensive Biomaterials, (pp. 329-346). Netherlands: Elsevier.

Journals

  • Lee, P., Bax, D., Bilek, M., Weiss, A. (2014). A Novel Cell Adhesion Region in Tropoelastin Mediates Attachment to Integrin ανβ5. The Journal of Biological Chemistry, 289(3), 1467-1477. [More Information]
  • Lee, P., Bax, D., Bilek, M., Weiss, A. (2014). A novel cell adhesion region in tropoelastin that mediates attachment to integrin alphaVbeta5. The Journal of Biological Chemistry, 289(3), 1467-1477. [More Information]
  • Liu, H., Wise, S., Rnjak-Kovacina, J., Kaplan, D., Bilek, M., Weiss, A., Fei, J., Bao, B. (2014). Biocompatibility of silk-tropoelastin protein polymers. Biomaterials, 35(19), 5138-5147. [More Information]
  • Fathi, A., Mithieux, S., Wei, H., Chrzanowski, W., Valtchev, P., Weiss, A., Dehghani, F. (2014). Elastin based cell-laden injectable hydrogels with tunable gelation, mechanical and biodegradation properties. Biomaterials, 35(21), 5425-5435. [More Information]
  • Hajian, H., Wise, S., Bax, D., Kondyurin, A., Waterhouse, A., Dunn, L., Kielty, C., Yu, Y., Weiss, A., Bilek, M., Bannon, P., et al (2014). Immobilisation of a fibrillin-1 fragment enhances the biocompatibility of PTFE. Colloids And Surfaces B: Biointerfaces, 116, 544-552. [More Information]
  • Fatoux-Ardore, M., Peysselon, F., Weiss, A., Bastien, P., Pratlong, F., Ricard-Blum, S. (2014). Large-scale investigation of Leishmania interaction networks with the host extracellular matrix by surface plasmon resonance imaging. Infection and Immunity, 82(2), 594-606. [More Information]
  • Bax, D., Kondyurin, A., Waterhouse, A., McKenzie, D., Weiss, A., Bilek, M. (2014). Surface plasma modification and tropoelastin coating of a polyurethane co-polymer for enhanced cell attachment and reduced thrombogenicity. Biomaterials, 35(25), 6797-6809-6797-6809. [More Information]
  • Wise, S., Yeo, G., Hiob, M., Rnjak-Kovacina, J., Kaplan, D., Ng, M., Weiss, A. (2014). Tropoelastin: A versatile, bioactive assembly module. Acta Biomaterialia, 10(4), 1532-1541. [More Information]
  • Wise, S., Yeo, G., Hiob, M., Rnjak-Kovacina, J., Kaplan, D., Ng, M., Weiss, A. (2014). Tropoelastin: A versatile, bioactive assembly module. Acta Biomaterialia, 10(4), 1532-1541. [More Information]
  • Hu, X., Tang-Schomer, M., Huang, W., Xia, X., Weiss, A., Kaplan, D. (2013). Charge-Tunable Autoclaved Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Advanced Functional Materials, 23(31), 3875-3884. [More Information]
  • Saitow, C., Wise, S., Weiss, A., Castellot Jr, J., Kaplan, D. (2013). Elastin biology and tissue engineering with adult cells. Biomolecular Concepts, 4(2), 173-185. [More Information]
  • Almine, J., Wise, S., Hiob, M., Singh, N., Tiwari, K., Vali, S., Abbasi, T., Weiss, A. (2013). Elastin sequences trigger transient proinflammatory responses by human dermal fibroblasts. The FASEB Journal, 27(9), 3455-3465. [More Information]
  • Annabi, N., Mithieux, S., Camci-Unal, G., Dokmeci, M., Weiss, A., Khademhosseini, A. (2013). Elastomeric recombinant protein-based biomaterials. Biochemical Engineering Journal, 77, 110-118. [More Information]
  • Annabi, N., Mithieux, S., Zorlutuna, P., Camci-Unal, G., Weiss, A., Khademhosseini, A. (2013). Engineered cell-laden human protein-based elastomer. Biomaterials, 34(22), 5496-5505. [More Information]
  • Annabi, N., Tsang, K., Mithieux, S., Nikkhah, M., Ameri, A., Khademhosseini, A., Weiss, A. (2013). Highly elastic micropatterned hydrogel for engineering functional cardiac tissue. Advanced Functional Materials, 23(39), 4950-4959. [More Information]
  • Annabi, N., Selimovic, S., Acevedo Cox, J., Ribas, J., Bakooshli, M., Heintze, D., Weiss, A., Cropek, D., Khademhosseini, A. (2013). Hydrogel-coated microfluidic channels for cardiomyocyte culture. Lab on a Chip, 13(18), 3569-3577. [More Information]
  • Hirsh, S., Bilek, M., Bax, D., Kondyurin, A., Kosobrodova, E., Tsoutas, K., Tran, C., Waterhouse, A., Yin, Y., Nosworthy, N., McKenzie, D., Dos Remedios, C., Weiss, A., et al (2013). Ion Implanted, Radical-Rich Surfaces For The Rapid Covalent Immobilization Of Active Biomolecules. AIP Conference Proceedings, 1525, 364-369. [More Information]
  • Ghezzi, C., Rnjak-Kovacina, J., Weiss, A., Kaplan, D. (2013). Multifunctional Silk-Tropoelastin Biomaterial Systems. Israel Journal Of Chemistry, 53(9-10), 777-786. [More Information]
  • Hiob, M., Wise, S., Kondyurin, A., Waterhouse, A., Bilek, M., Ng, M., Weiss, A. (2013). The use of plasma-activated covalent attachment of early domains of tropoelastin to enhance vascular compatibility of surfaces. Biomaterials, 34(31), 7584-7591. [More Information]
  • Mithieux, S., Wise, S., Weiss, A. (2013). Tropoelastin - A multifaceted naturally smart material. Advanced Drug Delivery Reviews, 65(4), 421-428. [More Information]
  • Reddel, C., Cultrone, D., Rnjak-Kovacina, J., Weiss, A., Burgess, J. (2013). Tropoelastin modulates TGF-B1-induced expression of VEGF and CTGF in airway smooth muscle cells. Matrix biology: journal of the International Society for Matrix Biology, 32(7-8), 407-413. [More Information]
  • Nivison-Smith, L., Weiss, A. (2012). Alignment of human vascular smooth muscle cells on parallel electrospun synthetic elastin fibers. Journal of Biomedical Materials Research. Part A, 100A (1), 155-161. [More Information]
  • Bax, D., Tipa, R., Kondyurin, A., Higgins, M., Tsoutas, K., Gelmi, A., Wallace, G., McKenzie, D., Weiss, A., Bilek, M. (2012). Cell patterning via linker-free protein functionalization of an organic conducting polymer (polypyrrole) electrode. Acta Biomaterialia, 8(7), 2538-2548. [More Information]
  • Reddel, C., Weiss, A., Burgess, J. (2012). Elastin in asthma. Pulmonary Pharmacology & Therapeutics, 25(2), 144-153. [More Information]
  • Almine, J., Wise, S., Weiss, A. (2012). Elastin Signaling in Wound Repair. Birth Defects Research. Part C: Embryo Today Reviews, 96(3), 248-257. [More Information]
  • Zhao, H., Chen, X., Xie, B., Zhou, M., Gao, X., Zhang, X., Zhou, B., Weiss, A., Zhang, Y. (2012). Elastolytic Mechanism of a Novel M23 Metalloprotease Pseudoalterin from Deep-sea Pseudoalteromonas sp. CF6-2: cleaving not only glycyl bonds in the hydrophobic regions but also peptide bonds in the hydrophilic regions involved in cross-linking. Journal of Biological Chemistry, 287(47), 39710-39720. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Li, Z., Maitz, P., Young, C., Wang, Y., Weiss, A. (2012). Electrospun synthetic human elastin: collagen composite scaffolds for dermal tissue engineering. Acta Biomaterialia, 8(10), 3714-3722. [More Information]
  • Waterhouse, A., Wise, S., Yin, Y., Wu, B., James, B., Zreiqat, H., McKenzie, D., Bao, B., Weiss, A., Ng, M., Bilek, M. (2012). In vivo biocompatibility of a plasma-activated, coronary stent coating. Biomaterials, 33(32), 7984-7992. [More Information]
  • Le Brun, A., Chow, J., Bax, D., Nelson, A., Weiss, A., James, M. (2012). Molecular Orientation of Tropoelastin is Determined by Surface Hydrophobicity. Biomacromolecules, 13(2), 379-386. [More Information]
  • Wise, S., Waterhouse, A., Kondyurin, A., Bilek, M., Weiss, A. (2012). Plasma-based biofunctionalization of vascular implants. Nanomedicine, 7(12), 1907-1916. [More Information]
  • Hu, X., Cebe, P., Weiss, A., Omenetto, F., Kaplan, D. (2012). Protein-based composite materials. Materials Today, 15(5), 208-215. [More Information]
  • Ohgo, K., Niemczura, W., Seacat, B., Wise, S., Weiss, A., Kumashiro, K. (2012). Resolving Nitrogen-15 and Proton Chemical Shifts for Mobile Segments of Elastin with Two-dimensional NMR Spectroscopy. Journal of Biological Chemistry, 287(22), 18201-18209. [More Information]
  • Heinz, A., Jung, M., Jahreis, G., Rusciani, A., Duca, L., Debelle, L., Weiss, A., Neubert, R., Schmelzer, C. (2012). The action of neutrophil serine proteases on elastin and its precursor. Biochimie, 94(1), 192-202. [More Information]
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012). Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 109(8), 2878-2883. [More Information]
  • Wise, S., Byrom, M., Waterhouse, A., Bannon, P., Ng, M., Weiss, A. (2011). A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties. Acta Biomaterialia, 7(1), 295-303. [More Information]
  • Bax, D., Wang, Y., Li, Z., Maitz, P., McKenzie, D., Bilek, M., Weiss, A. (2011). Binding of the cell adhesive protein tropoelastin to PTFE through plasma immersion ion implantation treatment. Biomaterials, 32(22), 5100-5111. [More Information]
  • Yeo, G., Keeley, F., Weiss, A. (2011). Coacervation of tropoelastin. Advances in Colloid and Interface Science, 167(1-2), 94-103. [More Information]
  • Hayes, A., Lord, M., Smith, S., Smith, M., Whitelock, J., Weiss, A., Melrose, J. (2011). Colocalization in vivo and association in vitro of perlecan and elastin. Histochemistry and Cell Biology, 136, 437-454. [More Information]
  • Bax, D., McKenzie, D., Bilek, M., Weiss, A. (2011). Directed cell attachment by tropoelastin on masked plasma immersion ion implantation treated PTFE. Biomaterials, 32(28), 6710-6718. [More Information]
  • Waterhouse, A., Wise, S., Ng, M., Weiss, A. (2011). Elastin as a Nonthrombogenic Biomaterial. Tissue Engineering. Part B. Reviews, 17(2), 93-99. [More Information]
  • Annabi, N., Fathi, A., Mithieux, S., Weiss, A., Dehghani, F. (2011). Fabrication of Porous PCL/elastin Composite Scaffolds for Tissue Engineering Applications. Journal of Supercritical Fluids, 59, 157-167. [More Information]
  • Bilek, M., Bax, D., Kondyurin, A., Yin, Y., Nosworthy, N., Fisher, K., Waterhouse, A., Weiss, A., Dos Remedios, C., McKenzie, D. (2011). Free radical functionalization of surfaces to prevent adverse responses to biomedical devices. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(35), 14405-14410. [More Information]
  • Rnjak-Kovacina, J., Weiss, A. (2011). Increasing the Pore Size of Electrospun Scaffolds. Tissue Engineering. Part B. Reviews, 17(5), 365-372. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Mithieux, S., Weiss, A. (2011). Severe burn injuries and the role of elastin in the design of dermal substitutes. Tissue Engineering. Part B. Reviews, 17(2), 81-91. [More Information]
  • Baldock, C., Oberhauser, A., Ma, L., Lammie, D., Siegler, V., Mithieux, S., Tu, Y., Chow, J., Suleman, F., Malfois, M., Weiss, A., et al (2011). Shape of Tropoelastin, the Highly Extensible Protein That Controls Human Tissue Elasticity. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(11), 4322-4327. [More Information]
  • Waterhouse, A., Bax, D., Wise, S., Yin, Y., Dunn, L., Yeo, G., Ng, M., Bilek, M., Weiss, A. (2011). Stability of a Therapeutic Layer of Immobilized Recombinant Human Tropoelastin on a Plasma-Activated Coated Surface. Pharmaceutical Research, 28(6), 1415-1421. [More Information]
  • McGrath, A., Mithieux, S., Collyer, C., Bakhuis, J., van den Berg, M., Sein, A., Heinz, A., Schmelzer, C., Weiss, A., Guss, M. (2011). Structure and Activity of Aspergillus nidulans Copper Amine Oxidase. Biochemistry, 50(25), 5718-5730. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Li, Z., Maitz, P., Young, C., Wang, Y., Weiss, A. (2011). Tailoring the porosity and pore size of electrospun synthetic human elastin scaffolds for dermal tissue engineering. Biomaterials, 32(28), 6729-6736. [More Information]
  • Annabi, N., Fathi, A., Mithieux, S., Martens, P., Weiss, A., Dehghani, F. (2011). The effect of elastin on chondrocyte adhesion and proliferation on poly (3-caprolactone)/elastin composites. Biomaterials, 32(6), 1517-1525. [More Information]
  • Hu, X., Park, S., Gil, E., Xia, X., Weiss, A., Kaplan, D. (2011). The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials, 32(34), 8979-8989. [More Information]
  • Bax, D., Liu, S., McKenzie, D., Bilek, M., Weiss, A. (2011). Tropoelastin Switch and Modulated Endothelial Cell Bindingto PTFE. Journal of Bionanoscience, 1, 123-127. [More Information]
  • Hu, X., Wang, X., Rnjak-Kovacina, J., Weiss, A., Kaplan, D. (2010). Biomaterials derived from silk-tropoelastin protein systems. Biomaterials, 31(32), 8121-8131. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2010). Cross-linked open-pore elastic hydrogels based on tropoelastin, elastin and high pressure CO(2). Biomaterials, 31(7), 1655-1665. [More Information]
  • Heinz, A., Jung, M., Duca, L., Sippl, W., Taddese, S., Ihling, C., Rusciani, A., Jahreis, G., Weiss, A., Neubert, R., et al (2010). Degradation of tropoelastin by matrix metalloproteinases - cleavage site specificities and release of matrikines. The FEBS Journal, 277(8), 1939-1956. [More Information]
  • Almine, J., Bax, D., Mithieux, S., Nivison-Smith, L., Rnjak-Kovacina, J., Waterhouse, A., Wise, S., Weiss, A. (2010). Elastin-based materials. Chemical Society Reviews, 39(9), 3371-3379. [More Information]
  • Dyksterhuis, L., Weiss, A. (2010). Homology models for domains 21-23 of human tropoelastin shed light on lysine crosslinking. Biochemical and Biophysical Research Communications, 396(4), 870-873. [More Information]
  • Waterhouse, A., Bax, D., Wise, S., Yin, Y., Dunn, L., Yeo, G., Ng, M., Bilek, M., Weiss, A. (2010). Stability of a Therapeutic Layer of Immobilized Recombinant Human Tropoelastin on a Plasma-Activated Coated Surface. Pharmaceutical Research, , 1-7. [More Information]
  • Tu, Y., Wise, S., Weiss, A. (2010). Stages in tropoelastin coalescence during synthetic elastin hydrogel formation. Micron, 41, 268-272. [More Information]
  • Muiznieks, L., Weiss, A., Keeley, F. (2010). Structural disorder and dynamics of elastin. Biochemistry and Cell Biology-Biochimie et Biologie Cellulaire, 88(2), 239-250. [More Information]
  • Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010). Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature Biotechnology, 28(10), 1123-1128. [More Information]
  • Tu, Y., Mithieux, S., Annabi, N., Boughton, E., Weiss, A. (2010). Synthetic elastin hydrogels that are coblended with heparin display substantial swelling, increased porosity, and improved cell penetration. Journal of Biomedical Materials Research. Part A, 95A(4), 1215-1222. [More Information]
  • Nivison-Smith, L., Rnjak-Kovacina, J., Weiss, A. (2010). Synthetic human elastin microfibers: Stable cross-linked tropoelastin and cell interactive constructs for tissue engineering applications. Acta Biomaterialia, 6, 354-359. [More Information]
  • Waterhouse, A., Yin, Y., Wise, S., Bax, D., McKenzie, D., Bilek, M., Weiss, A., Ng, M. (2010). The immobilization of recombinant human tropoelastin on metals using a plasma-activated coating to improve the biocompatibility of coronary stents. Biomaterials, 31(32), 8332-8340. [More Information]
  • Bax, D., McKenzie, D., Weiss, A., Bilek, M. (2010). The linker-free covalent attachment of collagen to plasma immersion ion implantation treated polytetrafluoroethylene and subsequent cell-binding activity. Biomaterials, 31(9), 2526-2534. [More Information]
  • Tu, Y., Weiss, A. (2010). Transient tropoelastin nanoparticles are early-stage intermediates in the coacervation of human tropoelastin whose aggregation is facilitated by heparan sulfate and heparin decasaccharides. Matrix biology: journal of the International Society for Matrix Biology, 29, 152-159. [More Information]
  • Naumann, C., Mithieux, S., Szekely, D., Tu, Y., Weiss, A., Kuchel, P. (2009). "Setting paint" analogy for the hydrophobic self-association of tropoelastin into elastin-like hydrogel. Biopolymers : Peptide Science, 91(5), 321-330. [More Information]
  • Bax, D., Rodgers, U., Bilek, M., Weiss, A. (2009). Cell adhesion to tropoelastin is mediated via the Cterminal GRKRK motif and integrin αvβ3. Journal of Biological Chemistry, 284(42), 28616-28623. [More Information]
  • Yin, Y., Wise, S., Nosworthy, N., Waterhouse, A., Bax, D., Youssef, H., Byrom, M., Bilek, M., McKenzie, D., Weiss, A., Ng, M. (2009). Covalent immobilisation of tropoelastin on a plasma deposited interface for enhancement of endothelialisation on metal surfaces. Biomaterials, 30(9), 1675-1681. [More Information]
  • Yin, Y., Fisher, K., Nosworthy, N., Bax, D., Rubanov, S., Gong, B., Weiss, A., McKenzie, D., Bilek, M. (2009). Covalently Bound Biomimetic Layers on Plasma Polymers with Graded Metallic Interfaces for in vivo Implants. Plasma Processes and Polymers, 6(10), 658-666. [More Information]
  • Wise, S., Mithieux, S., Weiss, A. (2009). Engineered tropoelastin and elastin-based biomaterials. Advances in Protein Chemistry and Structural Biology.
  • Mithieux, S., Tu, Y., Korkmaz, E., Braet, F., Weiss, A. (2009). In situ polymerization of tropoelastin in the absence of chemical cross-linking. Biomaterials, 30(4), 431-435. [More Information]
  • Taddese, S., Weiss, A., Jahreis, G., Neubert, R., Schmelzer, C. (2009). In vitro degradation of human tropoelastin by MMP-12 and the generation of matrikines from domain 24. Matrix biology: journal of the International Society for Matrix Biology, 28(2), 84-91. [More Information]
  • Yang, S., Xie, K., Yang, W., Zheng, R., Stevens, F., Korkmaz, E., Weiss, A., Ringer, S., Braet, F. (2009). In vitro studies of cells grown on the superconductor PROxFeAs. Micron, 40(4), 476-479. [More Information]
  • Bax, D., McKenzie, D., Weiss, A., Bilek, M. (2009). Linker-free covalent attachment of the extracellular matrix protein tropoelastin to a polymer surface for directed cell spreading. Acta Biomaterialia, 5(9), 3371-3381. [More Information]
  • Rnjak-Kovacina, J., Li, Z., Maitz, P., Wise, S., Weiss, A. (2009). Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin. Biomaterials, 30(32), 6469-6477. [More Information]
  • Annabi, N., Mithieux, S., Boughton, E., Ruys, A., Weiss, A., Dehghani, F. (2009). Synthesis of highly porous crosslinked elastin hydrogels and their interaction with fibroblasts in vitro. Biomaterials, 30(27), 4550-4557. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2009). The fabrication of elastin-based hydrogels using high pressure CO2. Biomaterials, 30(1), 1-7. [More Information]
  • Wise, S., Weiss, A. (2009). Tropoelastin. The International Journal of Biochemistry and Cell Biology, 41(3), 494-497. [More Information]
  • Dyksterhuis, L., Carter, E., Mithieux, S., Weiss, A. (2009). Tropoelastin as a thermodynamically unfolded premolten globule protein: The effect of trimethylamine N-oxide on structure and coacervation. Archives of Biochemistry and Biophysics, 487(2), 79-84. [More Information]
  • MacDonald, C., Morrow, R., Weiss, A., Bilek, M. (2008). Covalent attachment of functional protein to polymer surfaces: a novel one-step dry process. Journal of the Royal Society. Interface, 5(23), 663-669. [More Information]
  • Dehghani, F., Annabi, N., Valtchev, P., Mithieux, S., Weiss, A., Kazarian, S., Tay, F. (2008). Effect of dense gas CO2 on the coacervation of elastin. Biomacromolecules, 9(4), 1100-1105. [More Information]
  • Tu, Y., Weiss, A. (2008). Glycosaminoglycan-mediated coacervation of tropoelastin abolishes the critical concentration, accelerates coacervate formation, and facilitates spherule fusion: implications for tropoelastin microassembly. Biomacromolecules, 9(7), 1739-1744. [More Information]
  • Taddese, S., Weiss, A., Neubert, R., Schmelzer, C. (2008). Mapping of macrophage elastase cleavage sites in insoluble human skin elastin. Matrix biology: journal of the International Society for Matrix Biology, 27, 420-428. [More Information]
  • Muiznieks, L., Weiss, A. (2007). Flexibility in the Solution Structure of Human Tropoelastin. Biochemistry, 46(27), 8196-8205. [More Information]
  • Keane, F., Clarke, A., Foster, T., Weiss, A. (2007). The N-Terminal A Domain of Staphylococcus aureus Fibronectin-Binding Protein A Binds to Tropoelastin. Biochemistry, 46(24), 7226-7232.
  • Riley, L., Roufogalis, B., Li, G., Weiss, A. (2006). A radioassay for synaptic core complex assembly: Screening of herbal extracts for effectors. Analytical Biochemistry, 357(1), 50-57. [More Information]
  • Nicoloff, G., Weiss, A., Iotova, V., Tzaneva, V., Petrova, C., Domuschieva, N., Nikolov, A., Tzvetanov, P., Christova, P. (2006). Abnormal levels of serum antielastin antibodies in children with diabetes mellitus type 1. Journal of investigative medicine, 54(8), 461-467. [More Information]
  • Lemire, J., Patis, C., Gordon, L., Sandy, J., Toole, B., Weiss, A. (2006). Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mechanisms of ageing and development. [More Information]
  • Dyksterhuis, L., Baldock, C., Lammie, D., Wess, T., Weiss, A. (2006). Domains 17-27 of tropoelastin contain key regions of contact for coacervation and contain an unusual turn-containing crosslinking domain. Matrix biology: journal of the International Society for Matrix Biology, 26 (doi:10.1016/j.matbio.2006.10.002)(2), 125-135. [More Information]
  • Clarke, A., Arnspang, E., Mithieux, S., Korkmaz, E., Braet, F., Weiss, A. (2006). Tropoelastin Massively Associates during Coacervation To Form Quantized Protein Spheres. Biochemistry, 45(33), 9989-9996. [More Information]
  • Mithieux, S., Wise, S., Raftery, M., Starcher, B., Weiss, A. (2005). A model two-component system for studying the architecture of elastin assembly in vitro. Journal of Structural Biology, 149(3), 282-289. [More Information]
  • Rodgers, U., Weiss, A. (2005). Cellular interactions with elastin. Pathologie et Biologie, 53(7), 390-398. [More Information]
  • Getie, M., Schmelzer, C., Weiss, A., Neubert, R. (2005). Complementary mass spectrometric techniques to achieve complete sequence coverage of recombinant human tropoelastin. Rapid Communications in Mass Spectrometry, 19(20), 2989-2993.
  • Mithieux, S., Weiss, A. (2005). Elastin. Advances in protein chemistry, 70, 437-461. [More Information]
  • Mackay, J., Muiznieks, L., Toonkool, P., Weiss, A. (2005). The hydrophobic domain 26 of human tropoelastin is unstructured in solution. Journal of Structural Biology, 150(2), 154-162. [More Information]
  • Rodgers, U., Weiss, A. (2004). Integrin Alpha(V)Beta(3) Binds A Unique Non-Rgd Site Near The C-Terminus Of Human Tropoelastin. Biochimie, 86(3), 173-178. [More Information]
  • Reddel, C., Weiss, A. (2004). Lamin A Expression Levels Are Unperturbed At The Normal And Mutant Alleles But Display Partial Splice Site Selection In Hutchinson-Gilford Progeria Syndrome. Journal of Medical Genetics, 41(9), 715-717.
  • Clarke, A., Weiss, A. (2004). Microfibril-Associated Glycoprotein-1 Binding To Tropoelastin - Multiple Binding Sites And The Role Of Divalent Cations. The FEBS Journal, 271(14), 3085-3090.
  • Rock, M., Cain, S., Freeman, L., Morgan, A., Mellody, K., Marson, A., Shuttleworth, C., Weiss, A., Kielty, C. (2004). Molecular Basis Of Elastic Fiber Formation - Critical Interactions And A Tropoelastin-Fibrillin-1 Cross-Link. Journal of Biological Chemistry, 279(22), 23748-23758.
  • Mithieux, S., Rasko, J., Weiss, A. (2004). Synthetic Elastin Hydrogels Derived From Massive Elastic Assemblies Of Self-Organized Human Protein Monomers. Biomaterials, 25(20), 4921-4927. [More Information]
  • Kummerfeld, S., Weiss, A., Fekete, A., Jermiin, L. (2003). AMID: autonomous modeler of intragenic duplication. Applied Bioinformatics, 2(3), 169-176.
  • Robinson, L., Karlsson, N., Weiss, A., Packer, N. (2003). Proteomic analysis of the genetic premature aging disease Hutchinson Gilford Progeria Syndrome reveals differential protein expression and glycosylation. Journal of Proteome Research, 2(5), 556-557.
  • Jensen, S., Andersen, P., Vrhovski, B., Weiss, A. (2003). Rational design of tropoelastin peptide-based inhibitors of metalloproteinases. Archives of Biochemistry and Biophysics, 409(2), 335-340.
  • Muiznieks, L., Jensen, S., Weiss, A. (2003). Structural changes and facilitated association of tropelastin. Archives of Biochemistry and Biophysics, 410(2), 317-323.
  • Lim, Y., Hoog, J., Gardner, P., Ranganathan, S., Andersson, S., Subbiah, S., Tan, T., Hide, W., Weiss, A. (2003). The S-Star Trial Bioinformatics Course. Biochemistry and Molecular Biology Education, 31(1), 20-23. [More Information]
  • Weiss, A., O'Brien, M. (2001). A novel B(1-4) galactosyltransferase gene silent mutation (594C>T) associated with Hutchinson-Gilford progeria. Human Mutation, 17, 355-355.
  • Dedic, J., Weiss, A., Yu, B., Trent, R., Katahira, J., Urban, Z. (2001). A novel elastin gene mutation (1281delC) in a family with supravalvular aortic stenosis: a mutation cluster within exon 20. Human Mutation, 17, 81-81.
  • Tchan, M., Weiss, A. (2001). Asn78 and His81 form a destabilizing locus within the Max HLH-LZ homodimer. FEBS Letters, 509, 177-180.
  • Wiley, S., Weiss, A., Sangster, N., Walker, J., Hoekstra, R., Roos, M., Tait, A. (2001). Cloning and structural analysis of partial acetylcholine receptor subunit genes from the parasitic nematode Teladorsagia circumcincta. Veterinary Parasitology, 97, 329-335.
  • Toonkool, P., Weiss, A. (2001). Expression of recombinant human tropoelastin in Saccharomyces cerevisiae containing a synthetic gene with a high codon adaptation index coupled to the SUC2 invertase signal sequence. Acta Biotechnologica, 21, 189-193.
  • Toonkool, P., Jensen, S., Weiss, A., Maxwell, A. (2001). Hydrophobic domains of human tropoelastin interact in a context-dependent manner. Journal of Biological Chemistry, 276, 44575-44580.
  • Weiss, A., Mithieux, S., Stone,, P., Morris, S., Griffin, S. (2001). Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic Rat-1 fibroblasts as a source for lysyl oxidase. American Journal of Respiratory Cell and Molecular Biology, 24, 733-739.
  • Jensen, S., Weiss, A., Reinhardt, D., Gibson, M. (2001). Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1. Journal of Biological Chemistry, 276, 39661-39666.
  • Toonkool, P., Regan, D., Kuchel, P., Morris, M., Weiss, A. (2001). Thermodynamic and hydrodynamic properties of human tropoelastin. Journal of Biological Chemistry, 276, 28042-28050.

Conferences

  • Fathi, A., Wei, H., Chrzanowski, W., Weiss, A., Dehghani, F. (2014). Synthesis of thermo responsive co-polymer with active sites for protein conjugation for biomedical applications. 29th International Conference of the Polymer Processing Society 2013, Nuremberg, Germany: American Institute of Physics (AIP).
  • Momot, K., Powell, S., Mithieux, S., Weiss, A. (2013). Biomechanics of Synthetic Elastin: Insights from Magnetic Resonance Microimaging. 2013 International Conference on Materials Science and Chemical Engineering (MSCE 2013), Durnten-Zurich, Switzerland: Trans Tech Publications. [More Information]
  • Fathi, A., Wei, H., Chrzanowski, W., Weiss, A., Dehghani, F. (2012). Synthesis of Functionalized-thermo responsive-water soluble Co-polymer for Conjugation to Protein for Biomedical Applications. 2012 MRS Fall Meeting, Boston, USA: Cambridge University Press. [More Information]
  • Bilek, M., McKenzie, D., Bax, D., Kondyurin, A., Yin, Y., Nosworthy, N., Hirsh, S., Fisher, K., Weiss, A. (2011). Universal biomolecule binding interlayers created by energetic ion bombardment. 2011 Materials Research Society (MRS) Spring Meeting. Cambridge University Press. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2008). Fabrication of a crosslinked hydrogel using dense gas technology. 2008 Materials Research Society (MRS) Fall Meeting, Boston, USA: Materials Research Society.

Patents

  • Weiss, A. (2010). Tropoelastin Derivatives. Patent No. 1007555, 636948, 7193043, 7803577. France, Germany, Republic of Korea, United Kingdom.
  • Weiss, A. (2009). Protease Susceptibility II. Patent No. 1100815, 4342731, 7229788.
  • Martin, S., Weiss, A. (2009). Synthetic Tropoelastin. Patent No. 2151883. Canada.
  • Weiss, A., Mithieux, S., Regaglia, O. (2008). Synthetic Polynucleotides. Patent No. 0746612, 69334243.9. France, Germany, Italy, Sweden, Switzerland, United Kingdom.
  • Ng, M., Weiss, A., Wise, S. (2008). Patent No. WO2008/037028. USA, Europe, Australia.

2014

  • Lee, P., Bax, D., Bilek, M., Weiss, A. (2014). A Novel Cell Adhesion Region in Tropoelastin Mediates Attachment to Integrin ανβ5. The Journal of Biological Chemistry, 289(3), 1467-1477. [More Information]
  • Lee, P., Bax, D., Bilek, M., Weiss, A. (2014). A novel cell adhesion region in tropoelastin that mediates attachment to integrin alphaVbeta5. The Journal of Biological Chemistry, 289(3), 1467-1477. [More Information]
  • Liu, H., Wise, S., Rnjak-Kovacina, J., Kaplan, D., Bilek, M., Weiss, A., Fei, J., Bao, B. (2014). Biocompatibility of silk-tropoelastin protein polymers. Biomaterials, 35(19), 5138-5147. [More Information]
  • Fathi, A., Mithieux, S., Wei, H., Chrzanowski, W., Valtchev, P., Weiss, A., Dehghani, F. (2014). Elastin based cell-laden injectable hydrogels with tunable gelation, mechanical and biodegradation properties. Biomaterials, 35(21), 5425-5435. [More Information]
  • Hajian, H., Wise, S., Bax, D., Kondyurin, A., Waterhouse, A., Dunn, L., Kielty, C., Yu, Y., Weiss, A., Bilek, M., Bannon, P., et al (2014). Immobilisation of a fibrillin-1 fragment enhances the biocompatibility of PTFE. Colloids And Surfaces B: Biointerfaces, 116, 544-552. [More Information]
  • Fatoux-Ardore, M., Peysselon, F., Weiss, A., Bastien, P., Pratlong, F., Ricard-Blum, S. (2014). Large-scale investigation of Leishmania interaction networks with the host extracellular matrix by surface plasmon resonance imaging. Infection and Immunity, 82(2), 594-606. [More Information]
  • Bax, D., Kondyurin, A., Waterhouse, A., McKenzie, D., Weiss, A., Bilek, M. (2014). Surface plasma modification and tropoelastin coating of a polyurethane co-polymer for enhanced cell attachment and reduced thrombogenicity. Biomaterials, 35(25), 6797-6809-6797-6809. [More Information]
  • Fathi, A., Wei, H., Chrzanowski, W., Weiss, A., Dehghani, F. (2014). Synthesis of thermo responsive co-polymer with active sites for protein conjugation for biomedical applications. 29th International Conference of the Polymer Processing Society 2013, Nuremberg, Germany: American Institute of Physics (AIP).
  • Wise, S., Yeo, G., Hiob, M., Rnjak-Kovacina, J., Kaplan, D., Ng, M., Weiss, A. (2014). Tropoelastin: A versatile, bioactive assembly module. Acta Biomaterialia, 10(4), 1532-1541. [More Information]
  • Wise, S., Yeo, G., Hiob, M., Rnjak-Kovacina, J., Kaplan, D., Ng, M., Weiss, A. (2014). Tropoelastin: A versatile, bioactive assembly module. Acta Biomaterialia, 10(4), 1532-1541. [More Information]

2013

  • Momot, K., Powell, S., Mithieux, S., Weiss, A. (2013). Biomechanics of Synthetic Elastin: Insights from Magnetic Resonance Microimaging. 2013 International Conference on Materials Science and Chemical Engineering (MSCE 2013), Durnten-Zurich, Switzerland: Trans Tech Publications. [More Information]
  • Hu, X., Tang-Schomer, M., Huang, W., Xia, X., Weiss, A., Kaplan, D. (2013). Charge-Tunable Autoclaved Silk-Tropoelastin Protein Alloys That Control Neuron Cell Responses. Advanced Functional Materials, 23(31), 3875-3884. [More Information]
  • Saitow, C., Wise, S., Weiss, A., Castellot Jr, J., Kaplan, D. (2013). Elastin biology and tissue engineering with adult cells. Biomolecular Concepts, 4(2), 173-185. [More Information]
  • Almine, J., Wise, S., Hiob, M., Singh, N., Tiwari, K., Vali, S., Abbasi, T., Weiss, A. (2013). Elastin sequences trigger transient proinflammatory responses by human dermal fibroblasts. The FASEB Journal, 27(9), 3455-3465. [More Information]
  • Annabi, N., Mithieux, S., Camci-Unal, G., Dokmeci, M., Weiss, A., Khademhosseini, A. (2013). Elastomeric recombinant protein-based biomaterials. Biochemical Engineering Journal, 77, 110-118. [More Information]
  • Annabi, N., Mithieux, S., Zorlutuna, P., Camci-Unal, G., Weiss, A., Khademhosseini, A. (2013). Engineered cell-laden human protein-based elastomer. Biomaterials, 34(22), 5496-5505. [More Information]
  • Annabi, N., Tsang, K., Mithieux, S., Nikkhah, M., Ameri, A., Khademhosseini, A., Weiss, A. (2013). Highly elastic micropatterned hydrogel for engineering functional cardiac tissue. Advanced Functional Materials, 23(39), 4950-4959. [More Information]
  • Annabi, N., Selimovic, S., Acevedo Cox, J., Ribas, J., Bakooshli, M., Heintze, D., Weiss, A., Cropek, D., Khademhosseini, A. (2013). Hydrogel-coated microfluidic channels for cardiomyocyte culture. Lab on a Chip, 13(18), 3569-3577. [More Information]
  • Hirsh, S., Bilek, M., Bax, D., Kondyurin, A., Kosobrodova, E., Tsoutas, K., Tran, C., Waterhouse, A., Yin, Y., Nosworthy, N., McKenzie, D., Dos Remedios, C., Weiss, A., et al (2013). Ion Implanted, Radical-Rich Surfaces For The Rapid Covalent Immobilization Of Active Biomolecules. AIP Conference Proceedings, 1525, 364-369. [More Information]
  • Ghezzi, C., Rnjak-Kovacina, J., Weiss, A., Kaplan, D. (2013). Multifunctional Silk-Tropoelastin Biomaterial Systems. Israel Journal Of Chemistry, 53(9-10), 777-786. [More Information]
  • Rnjak-Kovacina, J., Weiss, A. (2013). The Role of Elastin in Wound Healing and Dermal Substitute Design. In Lars-Peter Kamolz, David Benjamin Lumenta (Eds.), Dermal Replacements in General, Burn, and Plastic Surgery: Tissue Engineering in Clinical Practice, (pp. 57-66). Vienna, Austria: Springer-Verlag.
  • Hiob, M., Wise, S., Kondyurin, A., Waterhouse, A., Bilek, M., Ng, M., Weiss, A. (2013). The use of plasma-activated covalent attachment of early domains of tropoelastin to enhance vascular compatibility of surfaces. Biomaterials, 34(31), 7584-7591. [More Information]
  • Mithieux, S., Wise, S., Weiss, A. (2013). Tropoelastin - A multifaceted naturally smart material. Advanced Drug Delivery Reviews, 65(4), 421-428. [More Information]
  • Reddel, C., Cultrone, D., Rnjak-Kovacina, J., Weiss, A., Burgess, J. (2013). Tropoelastin modulates TGF-B1-induced expression of VEGF and CTGF in airway smooth muscle cells. Matrix biology: journal of the International Society for Matrix Biology, 32(7-8), 407-413. [More Information]

2012

  • Nivison-Smith, L., Weiss, A. (2012). Alignment of human vascular smooth muscle cells on parallel electrospun synthetic elastin fibers. Journal of Biomedical Materials Research. Part A, 100A (1), 155-161. [More Information]
  • Bax, D., Tipa, R., Kondyurin, A., Higgins, M., Tsoutas, K., Gelmi, A., Wallace, G., McKenzie, D., Weiss, A., Bilek, M. (2012). Cell patterning via linker-free protein functionalization of an organic conducting polymer (polypyrrole) electrode. Acta Biomaterialia, 8(7), 2538-2548. [More Information]
  • Reddel, C., Weiss, A., Burgess, J. (2012). Elastin in asthma. Pulmonary Pharmacology & Therapeutics, 25(2), 144-153. [More Information]
  • Almine, J., Wise, S., Weiss, A. (2012). Elastin Signaling in Wound Repair. Birth Defects Research. Part C: Embryo Today Reviews, 96(3), 248-257. [More Information]
  • Zhao, H., Chen, X., Xie, B., Zhou, M., Gao, X., Zhang, X., Zhou, B., Weiss, A., Zhang, Y. (2012). Elastolytic Mechanism of a Novel M23 Metalloprotease Pseudoalterin from Deep-sea Pseudoalteromonas sp. CF6-2: cleaving not only glycyl bonds in the hydrophobic regions but also peptide bonds in the hydrophilic regions involved in cross-linking. Journal of Biological Chemistry, 287(47), 39710-39720. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Li, Z., Maitz, P., Young, C., Wang, Y., Weiss, A. (2012). Electrospun synthetic human elastin: collagen composite scaffolds for dermal tissue engineering. Acta Biomaterialia, 8(10), 3714-3722. [More Information]
  • Waterhouse, A., Wise, S., Yin, Y., Wu, B., James, B., Zreiqat, H., McKenzie, D., Bao, B., Weiss, A., Ng, M., Bilek, M. (2012). In vivo biocompatibility of a plasma-activated, coronary stent coating. Biomaterials, 33(32), 7984-7992. [More Information]
  • Le Brun, A., Chow, J., Bax, D., Nelson, A., Weiss, A., James, M. (2012). Molecular Orientation of Tropoelastin is Determined by Surface Hydrophobicity. Biomacromolecules, 13(2), 379-386. [More Information]
  • Wise, S., Waterhouse, A., Kondyurin, A., Bilek, M., Weiss, A. (2012). Plasma-based biofunctionalization of vascular implants. Nanomedicine, 7(12), 1907-1916. [More Information]
  • Hu, X., Cebe, P., Weiss, A., Omenetto, F., Kaplan, D. (2012). Protein-based composite materials. Materials Today, 15(5), 208-215. [More Information]
  • Ohgo, K., Niemczura, W., Seacat, B., Wise, S., Weiss, A., Kumashiro, K. (2012). Resolving Nitrogen-15 and Proton Chemical Shifts for Mobile Segments of Elastin with Two-dimensional NMR Spectroscopy. Journal of Biological Chemistry, 287(22), 18201-18209. [More Information]
  • Fathi, A., Wei, H., Chrzanowski, W., Weiss, A., Dehghani, F. (2012). Synthesis of Functionalized-thermo responsive-water soluble Co-polymer for Conjugation to Protein for Biomedical Applications. 2012 MRS Fall Meeting, Boston, USA: Cambridge University Press. [More Information]
  • Heinz, A., Jung, M., Jahreis, G., Rusciani, A., Duca, L., Debelle, L., Weiss, A., Neubert, R., Schmelzer, C. (2012). The action of neutrophil serine proteases on elastin and its precursor. Biochimie, 94(1), 192-202. [More Information]
  • Yeo, G., Baldock, C., Tuukkanen, A., Roessle, M., Dyksterhuis, L., Wise, S., Matthews, J., Mithieux, S., Weiss, A. (2012). Tropoelastin bridge region positions the cell-interactive C terminus and contributes to elastic fiber assembly. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 109(8), 2878-2883. [More Information]

2011

  • Wise, S., Byrom, M., Waterhouse, A., Bannon, P., Ng, M., Weiss, A. (2011). A multilayered synthetic human elastin/polycaprolactone hybrid vascular graft with tailored mechanical properties. Acta Biomaterialia, 7(1), 295-303. [More Information]
  • Bax, D., Wang, Y., Li, Z., Maitz, P., McKenzie, D., Bilek, M., Weiss, A. (2011). Binding of the cell adhesive protein tropoelastin to PTFE through plasma immersion ion implantation treatment. Biomaterials, 32(22), 5100-5111. [More Information]
  • Yeo, G., Keeley, F., Weiss, A. (2011). Coacervation of tropoelastin. Advances in Colloid and Interface Science, 167(1-2), 94-103. [More Information]
  • Hayes, A., Lord, M., Smith, S., Smith, M., Whitelock, J., Weiss, A., Melrose, J. (2011). Colocalization in vivo and association in vitro of perlecan and elastin. Histochemistry and Cell Biology, 136, 437-454. [More Information]
  • Bax, D., McKenzie, D., Bilek, M., Weiss, A. (2011). Directed cell attachment by tropoelastin on masked plasma immersion ion implantation treated PTFE. Biomaterials, 32(28), 6710-6718. [More Information]
  • Waterhouse, A., Wise, S., Ng, M., Weiss, A. (2011). Elastin as a Nonthrombogenic Biomaterial. Tissue Engineering. Part B. Reviews, 17(2), 93-99. [More Information]
  • Nivison-Smith, L., Weiss, A. (2011). Elastin Based Constructs. In Daniel Eberli (Eds.), Regenerative Medicine and Tissue Engineering - Cells and Biomaterials, (pp. 323-340). Rijeka, Croatia: InTech Publishers.
  • Rnjak-Kovacina, J., Daamen, W., Pierna, M., Rodriguez-Cabello, J., Weiss, A. (2011). Elastin Biopolymers. In Ducheyne, P; Healy, K.E; Hutmacher, D.W; Grainger, D; Kirkpatrick, C.J (Eds.), Comprehensive Biomaterials, (pp. 329-346). Netherlands: Elsevier.
  • Annabi, N., Fathi, A., Mithieux, S., Weiss, A., Dehghani, F. (2011). Fabrication of Porous PCL/elastin Composite Scaffolds for Tissue Engineering Applications. Journal of Supercritical Fluids, 59, 157-167. [More Information]
  • Bilek, M., Bax, D., Kondyurin, A., Yin, Y., Nosworthy, N., Fisher, K., Waterhouse, A., Weiss, A., Dos Remedios, C., McKenzie, D. (2011). Free radical functionalization of surfaces to prevent adverse responses to biomedical devices. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(35), 14405-14410. [More Information]
  • Rnjak-Kovacina, J., Weiss, A. (2011). Increasing the Pore Size of Electrospun Scaffolds. Tissue Engineering. Part B. Reviews, 17(5), 365-372. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Mithieux, S., Weiss, A. (2011). Severe burn injuries and the role of elastin in the design of dermal substitutes. Tissue Engineering. Part B. Reviews, 17(2), 81-91. [More Information]
  • Baldock, C., Oberhauser, A., Ma, L., Lammie, D., Siegler, V., Mithieux, S., Tu, Y., Chow, J., Suleman, F., Malfois, M., Weiss, A., et al (2011). Shape of Tropoelastin, the Highly Extensible Protein That Controls Human Tissue Elasticity. Proceedings of the National Academy of Sciences (PNAS) of the United States of America, 108(11), 4322-4327. [More Information]
  • Waterhouse, A., Bax, D., Wise, S., Yin, Y., Dunn, L., Yeo, G., Ng, M., Bilek, M., Weiss, A. (2011). Stability of a Therapeutic Layer of Immobilized Recombinant Human Tropoelastin on a Plasma-Activated Coated Surface. Pharmaceutical Research, 28(6), 1415-1421. [More Information]
  • McGrath, A., Mithieux, S., Collyer, C., Bakhuis, J., van den Berg, M., Sein, A., Heinz, A., Schmelzer, C., Weiss, A., Guss, M. (2011). Structure and Activity of Aspergillus nidulans Copper Amine Oxidase. Biochemistry, 50(25), 5718-5730. [More Information]
  • Rnjak-Kovacina, J., Wise, S., Li, Z., Maitz, P., Young, C., Wang, Y., Weiss, A. (2011). Tailoring the porosity and pore size of electrospun synthetic human elastin scaffolds for dermal tissue engineering. Biomaterials, 32(28), 6729-6736. [More Information]
  • Annabi, N., Fathi, A., Mithieux, S., Martens, P., Weiss, A., Dehghani, F. (2011). The effect of elastin on chondrocyte adhesion and proliferation on poly (3-caprolactone)/elastin composites. Biomaterials, 32(6), 1517-1525. [More Information]
  • Hu, X., Park, S., Gil, E., Xia, X., Weiss, A., Kaplan, D. (2011). The influence of elasticity and surface roughness on myogenic and osteogenic-differentiation of cells on silk-elastin biomaterials. Biomaterials, 32(34), 8979-8989. [More Information]
  • Bax, D., Liu, S., McKenzie, D., Bilek, M., Weiss, A. (2011). Tropoelastin Switch and Modulated Endothelial Cell Bindingto PTFE. Journal of Bionanoscience, 1, 123-127. [More Information]
  • Bilek, M., McKenzie, D., Bax, D., Kondyurin, A., Yin, Y., Nosworthy, N., Hirsh, S., Fisher, K., Weiss, A. (2011). Universal biomolecule binding interlayers created by energetic ion bombardment. 2011 Materials Research Society (MRS) Spring Meeting. Cambridge University Press. [More Information]

2010

  • Hu, X., Wang, X., Rnjak-Kovacina, J., Weiss, A., Kaplan, D. (2010). Biomaterials derived from silk-tropoelastin protein systems. Biomaterials, 31(32), 8121-8131. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2010). Cross-linked open-pore elastic hydrogels based on tropoelastin, elastin and high pressure CO(2). Biomaterials, 31(7), 1655-1665. [More Information]
  • Heinz, A., Jung, M., Duca, L., Sippl, W., Taddese, S., Ihling, C., Rusciani, A., Jahreis, G., Weiss, A., Neubert, R., et al (2010). Degradation of tropoelastin by matrix metalloproteinases - cleavage site specificities and release of matrikines. The FEBS Journal, 277(8), 1939-1956. [More Information]
  • Almine, J., Bax, D., Mithieux, S., Nivison-Smith, L., Rnjak-Kovacina, J., Waterhouse, A., Wise, S., Weiss, A. (2010). Elastin-based materials. Chemical Society Reviews, 39(9), 3371-3379. [More Information]
  • Dyksterhuis, L., Weiss, A. (2010). Homology models for domains 21-23 of human tropoelastin shed light on lysine crosslinking. Biochemical and Biophysical Research Communications, 396(4), 870-873. [More Information]
  • Waterhouse, A., Bax, D., Wise, S., Yin, Y., Dunn, L., Yeo, G., Ng, M., Bilek, M., Weiss, A. (2010). Stability of a Therapeutic Layer of Immobilized Recombinant Human Tropoelastin on a Plasma-Activated Coated Surface. Pharmaceutical Research, , 1-7. [More Information]
  • Tu, Y., Wise, S., Weiss, A. (2010). Stages in tropoelastin coalescence during synthetic elastin hydrogel formation. Micron, 41, 268-272. [More Information]
  • Muiznieks, L., Weiss, A., Keeley, F. (2010). Structural disorder and dynamics of elastin. Biochemistry and Cell Biology-Biochimie et Biologie Cellulaire, 88(2), 239-250. [More Information]
  • Holst, J., Watson, S., Lord, M., Eamegdool, S., Bax, D., Nivison-Smith, L., Kondyurin, A., Ma, L., Oberhauser, A., Weiss, A., Rasko, J. (2010). Substrate elasticity provides mechanical signals for the expansion of hemopoietic stem and progenitor cells. Nature Biotechnology, 28(10), 1123-1128. [More Information]
  • Tu, Y., Mithieux, S., Annabi, N., Boughton, E., Weiss, A. (2010). Synthetic elastin hydrogels that are coblended with heparin display substantial swelling, increased porosity, and improved cell penetration. Journal of Biomedical Materials Research. Part A, 95A(4), 1215-1222. [More Information]
  • Nivison-Smith, L., Rnjak-Kovacina, J., Weiss, A. (2010). Synthetic human elastin microfibers: Stable cross-linked tropoelastin and cell interactive constructs for tissue engineering applications. Acta Biomaterialia, 6, 354-359. [More Information]
  • Waterhouse, A., Yin, Y., Wise, S., Bax, D., McKenzie, D., Bilek, M., Weiss, A., Ng, M. (2010). The immobilization of recombinant human tropoelastin on metals using a plasma-activated coating to improve the biocompatibility of coronary stents. Biomaterials, 31(32), 8332-8340. [More Information]
  • Bax, D., McKenzie, D., Weiss, A., Bilek, M. (2010). The linker-free covalent attachment of collagen to plasma immersion ion implantation treated polytetrafluoroethylene and subsequent cell-binding activity. Biomaterials, 31(9), 2526-2534. [More Information]
  • Tu, Y., Weiss, A. (2010). Transient tropoelastin nanoparticles are early-stage intermediates in the coacervation of human tropoelastin whose aggregation is facilitated by heparan sulfate and heparin decasaccharides. Matrix biology: journal of the International Society for Matrix Biology, 29, 152-159. [More Information]
  • Weiss, A. (2010). Tropoelastin Derivatives. Patent No. 1007555, 636948, 7193043, 7803577. France, Germany, Republic of Korea, United Kingdom.

2009

  • Naumann, C., Mithieux, S., Szekely, D., Tu, Y., Weiss, A., Kuchel, P. (2009). "Setting paint" analogy for the hydrophobic self-association of tropoelastin into elastin-like hydrogel. Biopolymers : Peptide Science, 91(5), 321-330. [More Information]
  • Bax, D., Rodgers, U., Bilek, M., Weiss, A. (2009). Cell adhesion to tropoelastin is mediated via the Cterminal GRKRK motif and integrin αvβ3. Journal of Biological Chemistry, 284(42), 28616-28623. [More Information]
  • Yin, Y., Wise, S., Nosworthy, N., Waterhouse, A., Bax, D., Youssef, H., Byrom, M., Bilek, M., McKenzie, D., Weiss, A., Ng, M. (2009). Covalent immobilisation of tropoelastin on a plasma deposited interface for enhancement of endothelialisation on metal surfaces. Biomaterials, 30(9), 1675-1681. [More Information]
  • Yin, Y., Fisher, K., Nosworthy, N., Bax, D., Rubanov, S., Gong, B., Weiss, A., McKenzie, D., Bilek, M. (2009). Covalently Bound Biomimetic Layers on Plasma Polymers with Graded Metallic Interfaces for in vivo Implants. Plasma Processes and Polymers, 6(10), 658-666. [More Information]
  • Wise, S., Mithieux, S., Weiss, A. (2009). Engineered tropoelastin and elastin-based biomaterials. Advances in Protein Chemistry and Structural Biology.
  • Mithieux, S., Tu, Y., Korkmaz, E., Braet, F., Weiss, A. (2009). In situ polymerization of tropoelastin in the absence of chemical cross-linking. Biomaterials, 30(4), 431-435. [More Information]
  • Taddese, S., Weiss, A., Jahreis, G., Neubert, R., Schmelzer, C. (2009). In vitro degradation of human tropoelastin by MMP-12 and the generation of matrikines from domain 24. Matrix biology: journal of the International Society for Matrix Biology, 28(2), 84-91. [More Information]
  • Yang, S., Xie, K., Yang, W., Zheng, R., Stevens, F., Korkmaz, E., Weiss, A., Ringer, S., Braet, F. (2009). In vitro studies of cells grown on the superconductor PROxFeAs. Micron, 40(4), 476-479. [More Information]
  • Bax, D., McKenzie, D., Weiss, A., Bilek, M. (2009). Linker-free covalent attachment of the extracellular matrix protein tropoelastin to a polymer surface for directed cell spreading. Acta Biomaterialia, 5(9), 3371-3381. [More Information]
  • Rnjak-Kovacina, J., Li, Z., Maitz, P., Wise, S., Weiss, A. (2009). Primary human dermal fibroblast interactions with open weave three-dimensional scaffolds prepared from synthetic human elastin. Biomaterials, 30(32), 6469-6477. [More Information]
  • Weiss, A. (2009). Protease Susceptibility II. Patent No. 1100815, 4342731, 7229788.
  • Annabi, N., Mithieux, S., Boughton, E., Ruys, A., Weiss, A., Dehghani, F. (2009). Synthesis of highly porous crosslinked elastin hydrogels and their interaction with fibroblasts in vitro. Biomaterials, 30(27), 4550-4557. [More Information]
  • Martin, S., Weiss, A. (2009). Synthetic Tropoelastin. Patent No. 2151883. Canada.
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2009). The fabrication of elastin-based hydrogels using high pressure CO2. Biomaterials, 30(1), 1-7. [More Information]
  • Wise, S., Weiss, A. (2009). Tropoelastin. The International Journal of Biochemistry and Cell Biology, 41(3), 494-497. [More Information]
  • Dyksterhuis, L., Carter, E., Mithieux, S., Weiss, A. (2009). Tropoelastin as a thermodynamically unfolded premolten globule protein: The effect of trimethylamine N-oxide on structure and coacervation. Archives of Biochemistry and Biophysics, 487(2), 79-84. [More Information]

2008

  • MacDonald, C., Morrow, R., Weiss, A., Bilek, M. (2008). Covalent attachment of functional protein to polymer surfaces: a novel one-step dry process. Journal of the Royal Society. Interface, 5(23), 663-669. [More Information]
  • Dehghani, F., Annabi, N., Valtchev, P., Mithieux, S., Weiss, A., Kazarian, S., Tay, F. (2008). Effect of dense gas CO2 on the coacervation of elastin. Biomacromolecules, 9(4), 1100-1105. [More Information]
  • Annabi, N., Mithieux, S., Weiss, A., Dehghani, F. (2008). Fabrication of a crosslinked hydrogel using dense gas technology. 2008 Materials Research Society (MRS) Fall Meeting, Boston, USA: Materials Research Society.
  • Tu, Y., Weiss, A. (2008). Glycosaminoglycan-mediated coacervation of tropoelastin abolishes the critical concentration, accelerates coacervate formation, and facilitates spherule fusion: implications for tropoelastin microassembly. Biomacromolecules, 9(7), 1739-1744. [More Information]
  • Taddese, S., Weiss, A., Neubert, R., Schmelzer, C. (2008). Mapping of macrophage elastase cleavage sites in insoluble human skin elastin. Matrix biology: journal of the International Society for Matrix Biology, 27, 420-428. [More Information]
  • Weiss, A., Mithieux, S., Regaglia, O. (2008). Synthetic Polynucleotides. Patent No. 0746612, 69334243.9. France, Germany, Italy, Sweden, Switzerland, United Kingdom.
  • Ng, M., Weiss, A., Wise, S. (2008). Patent No. WO2008/037028. USA, Europe, Australia.

2007

  • Muiznieks, L., Weiss, A. (2007). Flexibility in the Solution Structure of Human Tropoelastin. Biochemistry, 46(27), 8196-8205. [More Information]
  • Keane, F., Clarke, A., Foster, T., Weiss, A. (2007). The N-Terminal A Domain of Staphylococcus aureus Fibronectin-Binding Protein A Binds to Tropoelastin. Biochemistry, 46(24), 7226-7232.

2006

  • Riley, L., Roufogalis, B., Li, G., Weiss, A. (2006). A radioassay for synaptic core complex assembly: Screening of herbal extracts for effectors. Analytical Biochemistry, 357(1), 50-57. [More Information]
  • Nicoloff, G., Weiss, A., Iotova, V., Tzaneva, V., Petrova, C., Domuschieva, N., Nikolov, A., Tzvetanov, P., Christova, P. (2006). Abnormal levels of serum antielastin antibodies in children with diabetes mellitus type 1. Journal of investigative medicine, 54(8), 461-467. [More Information]
  • Lemire, J., Patis, C., Gordon, L., Sandy, J., Toole, B., Weiss, A. (2006). Aggrecan expression is substantially and abnormally upregulated in Hutchinson-Gilford Progeria Syndrome dermal fibroblasts. Mechanisms of ageing and development. [More Information]
  • Dyksterhuis, L., Baldock, C., Lammie, D., Wess, T., Weiss, A. (2006). Domains 17-27 of tropoelastin contain key regions of contact for coacervation and contain an unusual turn-containing crosslinking domain. Matrix biology: journal of the International Society for Matrix Biology, 26 (doi:10.1016/j.matbio.2006.10.002)(2), 125-135. [More Information]
  • Clarke, A., Arnspang, E., Mithieux, S., Korkmaz, E., Braet, F., Weiss, A. (2006). Tropoelastin Massively Associates during Coacervation To Form Quantized Protein Spheres. Biochemistry, 45(33), 9989-9996. [More Information]

2005

  • Mithieux, S., Wise, S., Raftery, M., Starcher, B., Weiss, A. (2005). A model two-component system for studying the architecture of elastin assembly in vitro. Journal of Structural Biology, 149(3), 282-289. [More Information]
  • Rodgers, U., Weiss, A. (2005). Cellular interactions with elastin. Pathologie et Biologie, 53(7), 390-398. [More Information]
  • Getie, M., Schmelzer, C., Weiss, A., Neubert, R. (2005). Complementary mass spectrometric techniques to achieve complete sequence coverage of recombinant human tropoelastin. Rapid Communications in Mass Spectrometry, 19(20), 2989-2993.
  • Mithieux, S., Weiss, A. (2005). Elastin. Advances in protein chemistry, 70, 437-461. [More Information]
  • Mackay, J., Muiznieks, L., Toonkool, P., Weiss, A. (2005). The hydrophobic domain 26 of human tropoelastin is unstructured in solution. Journal of Structural Biology, 150(2), 154-162. [More Information]

2004

  • Rodgers, U., Weiss, A. (2004). Integrin Alpha(V)Beta(3) Binds A Unique Non-Rgd Site Near The C-Terminus Of Human Tropoelastin. Biochimie, 86(3), 173-178. [More Information]
  • Reddel, C., Weiss, A. (2004). Lamin A Expression Levels Are Unperturbed At The Normal And Mutant Alleles But Display Partial Splice Site Selection In Hutchinson-Gilford Progeria Syndrome. Journal of Medical Genetics, 41(9), 715-717.
  • Clarke, A., Weiss, A. (2004). Microfibril-Associated Glycoprotein-1 Binding To Tropoelastin - Multiple Binding Sites And The Role Of Divalent Cations. The FEBS Journal, 271(14), 3085-3090.
  • Rock, M., Cain, S., Freeman, L., Morgan, A., Mellody, K., Marson, A., Shuttleworth, C., Weiss, A., Kielty, C. (2004). Molecular Basis Of Elastic Fiber Formation - Critical Interactions And A Tropoelastin-Fibrillin-1 Cross-Link. Journal of Biological Chemistry, 279(22), 23748-23758.
  • Mithieux, S., Rasko, J., Weiss, A. (2004). Synthetic Elastin Hydrogels Derived From Massive Elastic Assemblies Of Self-Organized Human Protein Monomers. Biomaterials, 25(20), 4921-4927. [More Information]

2003

  • Kummerfeld, S., Weiss, A., Fekete, A., Jermiin, L. (2003). AMID: autonomous modeler of intragenic duplication. Applied Bioinformatics, 2(3), 169-176.
  • Robinson, L., Karlsson, N., Weiss, A., Packer, N. (2003). Proteomic analysis of the genetic premature aging disease Hutchinson Gilford Progeria Syndrome reveals differential protein expression and glycosylation. Journal of Proteome Research, 2(5), 556-557.
  • Jensen, S., Andersen, P., Vrhovski, B., Weiss, A. (2003). Rational design of tropoelastin peptide-based inhibitors of metalloproteinases. Archives of Biochemistry and Biophysics, 409(2), 335-340.
  • Muiznieks, L., Jensen, S., Weiss, A. (2003). Structural changes and facilitated association of tropelastin. Archives of Biochemistry and Biophysics, 410(2), 317-323.
  • Lim, Y., Hoog, J., Gardner, P., Ranganathan, S., Andersson, S., Subbiah, S., Tan, T., Hide, W., Weiss, A. (2003). The S-Star Trial Bioinformatics Course. Biochemistry and Molecular Biology Education, 31(1), 20-23. [More Information]

2001

  • Weiss, A., O'Brien, M. (2001). A novel B(1-4) galactosyltransferase gene silent mutation (594C>T) associated with Hutchinson-Gilford progeria. Human Mutation, 17, 355-355.
  • Dedic, J., Weiss, A., Yu, B., Trent, R., Katahira, J., Urban, Z. (2001). A novel elastin gene mutation (1281delC) in a family with supravalvular aortic stenosis: a mutation cluster within exon 20. Human Mutation, 17, 81-81.
  • Tchan, M., Weiss, A. (2001). Asn78 and His81 form a destabilizing locus within the Max HLH-LZ homodimer. FEBS Letters, 509, 177-180.
  • Wiley, S., Weiss, A., Sangster, N., Walker, J., Hoekstra, R., Roos, M., Tait, A. (2001). Cloning and structural analysis of partial acetylcholine receptor subunit genes from the parasitic nematode Teladorsagia circumcincta. Veterinary Parasitology, 97, 329-335.
  • Toonkool, P., Weiss, A. (2001). Expression of recombinant human tropoelastin in Saccharomyces cerevisiae containing a synthetic gene with a high codon adaptation index coupled to the SUC2 invertase signal sequence. Acta Biotechnologica, 21, 189-193.
  • Toonkool, P., Jensen, S., Weiss, A., Maxwell, A. (2001). Hydrophobic domains of human tropoelastin interact in a context-dependent manner. Journal of Biological Chemistry, 276, 44575-44580.
  • Weiss, A., Mithieux, S., Stone,, P., Morris, S., Griffin, S. (2001). Incorporation of recombinant human tropoelastin into extracellular matrices using nonelastogenic Rat-1 fibroblasts as a source for lysyl oxidase. American Journal of Respiratory Cell and Molecular Biology, 24, 733-739.
  • Jensen, S., Weiss, A., Reinhardt, D., Gibson, M. (2001). Protein interaction studies of MAGP-1 with tropoelastin and fibrillin-1. Journal of Biological Chemistry, 276, 39661-39666.
  • Toonkool, P., Regan, D., Kuchel, P., Morris, M., Weiss, A. (2001). Thermodynamic and hydrodynamic properties of human tropoelastin. Journal of Biological Chemistry, 276, 28042-28050.

To update your profile click here. For support on your academic profile contact .