Paper in Familial Cancer
- Meiser, B., Price, M.A., Butow, P.N., Rahman, B., Tucker, K., Cheah, B., Bickerstaffe, A., Hopper, J., Phillips, K.-A., Bennett, B., Tennant, C., Hopper, J.L., Milne, R.L., Weideman, P., Stanhope. Misperceptions of ovarian cancer risk in women at increased risk for hereditary ovarian cancer. Familial Cancer, 13 (2) pp. 153-162.
This study assessed the sociodemographic, medical and psychological predictors of accuracy of perceived risk in women at increased genetic risk for ovarian cancer. Women participating in a large cohort study who were at increased risk of ovarian and fallopian tube cancer, had no personal history of cancer and had ≥1 ovary in situ at cohort enrolment, were eligible. Women completed self-administered questionnaires and attended an interview at enrolment. Of 2,868 women unaffected with cancer at cohort enrolment, 561 were eligible. 335 women (59.8 %) overestimated their ovarian cancer risk, while 215 women (38.4 %) accurately estimated their risk, and 10 (1.8 %) underestimated it. Women who did not know their mutation status were more likely to overestimate their risk (OR 1.74, 95 % CI 1.10, 2.77, p = 0.018), as were those with higher cancer-specific anxiety (OR 1.05, 95 % CI 1.02, 1.08, p