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Dr Auriol Purdie

BSc (Hons) MSc PhD
Post Doctoral Fellow Farm Animal &
Veterinary Public Health  

C01A - Jl Shute - Camden
The University of Sydney

Telephone +61 2 9036 7743
Fax +61 2 9351 1618

Biographical details

Auriol holds a Bachelor of Science in Molecular Genetics from Kings College, London (UK), a Masters degree in the Immunology of Infectious Disease from the London School of Hygiene and Tropical Medicine (UK) and a Doctorate of Philosophy looking at the immunomodulatory effects of the antibiotics Ciprofloxacin and Moxifloxacin on healthy humans. The PhD was granted from the University of Aberdeen (UK). Prior to joining the faculty at the University of Sydney, Auriol completed two Post Doctoral Fellowships at The Roslin Institute (Edinburgh, UK).

The first looked at the pathogenesis of bovine spongiform encephalopathy in bovine and murine models and the second Fellowship studied the potential to utilise gene transduction to obtain proteins of medical interest from a chicken model. Auriol¿s research interest pertains to the pathogenesis of disease in host organisms with particular reference to the immune response and she is working within the Johne¿s research team.

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Themes

Animal Health

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Selected publications

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Journals

  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Plain, K., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary Immunology and Immunopathology, 149(1-2), 28-37.
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 35(2), 151-162.
  • Gurang, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine Immunology, 19(6), 855-864.
  • Gurang, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico screened Mycobacterium avium subsp. paratuberculosis (MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep. Veterinary Immunology and Immunopathology, 149(3-4), 186-196.
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(3), 197-208.
  • Begg, D., de Silva, K., Carter, N., Plain, K., Purdie (Williams), A., Whittington, R. (2011). Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology, 216(7), 840-846.
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2011). Indoleamine 2,3-Dioxygenase, Tryptophan Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic Mycobacterial Infection. Infection and Immunity, 79(9), 3821-3832.
  • Lyall, J., Irvine, R., Sherman, A., McKinley, T., Nunez, A., Purdie, A., Outtrim, L., Brown, I., Rolleston-Smith, G., Sang, H., et al (2011). Suppression of Avian Influenza Transmission in Genetically Modified Chickens. Science, 331(6014), 223-226.
  • Plain, K., Purdie (Williams), A., Begg, D., de Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease. Veterinary Immunology and Immunopathology, 137(1-2), 142-148.
  • Purdie (Williams), A., Galley, H., Watt, A., Webster, N. (2005). Differential effects of three antibiotics on T helper cell cytokine expression. Journal of Antimicrobial Chemotherapy, 56(3), 502-506.

2012

  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Plain, K., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary Immunology and Immunopathology, 149(1-2), 28-37.
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 35(2), 151-162.
  • Gurang, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine Immunology, 19(6), 855-864.
  • Gurang, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico screened Mycobacterium avium subsp. paratuberculosis (MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep. Veterinary Immunology and Immunopathology, 149(3-4), 186-196.

2011

  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(3), 197-208.
  • Begg, D., de Silva, K., Carter, N., Plain, K., Purdie (Williams), A., Whittington, R. (2011). Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology, 216(7), 840-846.
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2011). Indoleamine 2,3-Dioxygenase, Tryptophan Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic Mycobacterial Infection. Infection and Immunity, 79(9), 3821-3832.
  • Lyall, J., Irvine, R., Sherman, A., McKinley, T., Nunez, A., Purdie, A., Outtrim, L., Brown, I., Rolleston-Smith, G., Sang, H., et al (2011). Suppression of Avian Influenza Transmission in Genetically Modified Chickens. Science, 331(6014), 223-226.

2010

  • Plain, K., Purdie (Williams), A., Begg, D., de Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease. Veterinary Immunology and Immunopathology, 137(1-2), 142-148.

2005

  • Purdie (Williams), A., Galley, H., Watt, A., Webster, N. (2005). Differential effects of three antibiotics on T helper cell cytokine expression. Journal of Antimicrobial Chemotherapy, 56(3), 502-506.
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