Dr Douglas Begg

BSc, Dip for graduates, MSc, PhD
Research Fellow - Ovine Johne'
s disease in sheep

C01A - Jl Shute - Camden
The University of Sydney

Telephone +61 2 9036 7737
Fax +61 2 9351 1618

Biographical details

After completing his BSc majoring in Zoology, Doug went on to do a Diploma for graduates with a major in Microbiology.

In 2000 Doug completed his MSc in the Disease Research Laboratory at the University of Otago, New Zealand. His thesis examined the effect that different experimental housing conditions and environmental enrichment had on stress and immune responses of brush tail possums. Staying within the Disease Research Laboratory, Doug worked on experimental infection models for Mycobacterium paratuberculosis which causes Johne¿s disease in sheep. The immune responses from infected, diseased and vaccinated animals were examined. Doug joined the Farm Animal Health Group in 2005 and is continuing to study the pathogenesis of Johne¿s disease in sheep as well as advising on immunological studies carried out in other species of farmed animals.

Selected grants

2011

  • OJD/BJD: Diagnostic, predictive and preventative tools for Johne's disease in sheep and cattle; Whittington R, Begg D, de Silva K, Plain K, Purdie (Williams) A, Dhand N; Meat and Livestock Australia Ltd/Livestock Production Research and Development Program: Strategic and Applied Research Funding.

Selected publications

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Book Chapters

  • Begg, D., Whittington, R. (2010). Paratuberculosis in sheep. In Marcel A. Behr and Desmond M Collins. (Eds.), Paratuberculosis: organism, disease, control, (pp. 157-168). Wallingford, UK ; Cambridge, MA: CABI Publishing.

Journals

  • Gurung, R., Begg, D., Purdie (Williams), A., Whittington, R. (2014). Antigenicity in sheep of synthetic peptides derived from stress-regulated Mycobacterium avium subsp. paratuberculosis proteins and comparison with recombinant protein and complex native antigens. Veterinary Immunology and Immunopathology, 158(1-2), 46-52. [More Information]
  • Gurung, R., Purdie (Williams), A., Whittington, R., Begg, D. (2014). Cellular and humoral immune responses in sheep vaccinated with candidate antigens MAP2698c and MAP3567 from Mycobacterium avium subspecies paratuberculosis. Frontiers in Cellular and Infection Microbiology, 14(Article 93), 1-8. [More Information]
  • Eppleston, J., Begg, D., Dhand, N., Watt, B., Whittington, R. (2014). Environmental Survival of mycobacterium avium subsp. paratuberculosis in Different Climatic Zones of Eastern Australia. Applied and Environmental Microbiology, 80(8), 2337-2342. [More Information]
  • Thirunavukkarasu, S., Plain, K., de Silva, K., Begg, D., Whittington, R., Purdie (Williams), A. (2014). Expression of genes associated with cholesterol and lipid metabolism identified as a novel pathway in the early pathogenesis of Mycobacterium avium subspecies paratuberculosis - infection in cattle. Veterinary Immunology and Immunopathology, 160, 147-157. [More Information]
  • Plain, K., Marsh, I., Waldron, A., Galea, F., Whittington, A., Saunders, V., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2014). High-Throughput Direct Faecal PCR Assay to detect Mycobacterium avium subspecies paratuberculosis in sheep and cattle. Journal of Clinical Microbiology, 52(3), 745-757. [More Information]
  • Gurung, R., Begg, D., Purdie (Williams), A., Bach, H., Whittington, R. (2014). Immunoreactivity of protein tyrosine phosphatase A (PtpA) in sera from sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary Immunology and Immunopathology, 160, 129-132. [More Information]
  • Gurung, R., Begg, D., Purdie (Williams), A., de Silva, K., Bannantine, J., Whittington, R. (2014). Lymphoproliferative and IFN-y responses to stress-regulated Mycobacterium avium subspecies paratuberculosis recombinant proteins. Clinical and Vaccine Immunology, 21(6), 831-837. [More Information]
  • Gurung, R., Begg, D., Purdie (Williams), A., Bannantine, J., Whittington, R. (2013). Antigenicity of Recombinant Maltose Binding Protein-Mycobacterium avium subsp. Paratuberculosis Fusion Proteins with and without Factor Xa Cleaving. Clinical and Vaccine Immunology, 20(12), 1817-1826. [More Information]
  • de Silva, K., Browne, S., Begg, D., Whittington, R., Emery, D. (2013). Apoptosis of lymph node and peripheral blood cells in ovine Johne's disease. Veterinary Immunology and Immunopathology, 156(1-2), 82-90. [More Information]
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Dhand, N., Whittington, R. (2013). Can early host responses to mycobacterial infection predict eventual disease outcomes? Preventive Veterinary Medicine, 112, 203-212. [More Information]
  • Whittington, R., Whittington, A., Waldron, A., Begg, D., de Silva, K., Purdie (Williams), A., Plain, K. (2013). Development and validation of a liquid medium (M7H9C) for routine culture of Mycobacterium avium subsp. paratuberculosis to replace modified Bactec 12B medium. Journal of Clinical Microbiology, 51(12), 3993-4000. [More Information]
  • Miller, Y., Collins, A., Emery, D., Begg, D., Smits, R., Holyoake, P. (2013). Piglet performance and immunity is determined by the parity of both the birth dam and the rearing dam. Animal Production Science, 53(1), 46-51. [More Information]
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2013). Tissue localisation of Mycobacterium avium subspecies paratuberculosis following artificially induced intracellular and naked bacteraemia. Veterinary Microbiology, 162(1), 112-118. [More Information]
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Plain, K., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary Immunology and Immunopathology, 149(1-2), 28-37. [More Information]
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 35(2), 151-162. [More Information]
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine Immunology, 19(6), 855-864. [More Information]
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico screened Mycobacterium avium subsp. paratuberculosis (MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep. Veterinary Immunology and Immunopathology, 149(3-4), 186-196. [More Information]
  • Kawaji, S., Begg, D., Plain, K., Whittington, R. (2011). A longitudinal study to evaluate the diagnostic potential of a direct faecal quantitative PCR test for Johne's disease in sheep. Veterinary Microbiology, 148(1), 35-44. [More Information]
  • Zhong, L., Taylor, D., Begg, D., Whittington, R. (2011). Biomarker discovery for ovine paratuberculosis (Johne's disease) by Proteomic serum profiling. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(4), 315-326. [More Information]
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(3), 197-208. [More Information]
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2011). Culture of Mycobacterium avium subspecies paratuberculosis (MAP) from blood and extra-intestinal tissues in experimentally infected sheep. Veterinary Microbiology, 147(1-2), 127-132. [More Information]
  • Begg, D., de Silva, K., Carter, N., Plain, K., Purdie (Williams), A., Whittington, R. (2011). Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology, 216(7), 840-846. [More Information]
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2011). Indoleamine 2,3-Dioxygenase, Tryptophan Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic Mycobacterial Infection. Infection and Immunity, 79(9), 3821-3832. [More Information]
  • de Silva, K., Begg, D., Whittington, R. (2011). The interleukin 10 response in ovine Johne's disease. Veterinary Immunology and Immunopathology, 139(1), 10-16. [More Information]
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Bower (Goldsmith), K., Zhong, L., Kawaji, S., Emery, D., Whittington, R. (2010). Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of Mycobacterium avium subspecies paratuberculosis. Veterinary Microbiology, 141, 301-311.
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2010). Optimisation of culture of Mycobacterium avium subspecies  paratuberculosis from blood samples. Journal of Microbiological Methods, 80, 93-99. [More Information]
  • Bosward, K., Dhand, N., Begg, D., Thomson, P., Emery, D., Whittington, R. (2010). Optimization of a whole blood gamma interferon assay for the detection of sheep infected with mycobacterium avium subspecies paratuberculosis. Journal of Veterinary Diagnostic Investigation, 22(2), 210-217.
  • de Silva, K., Begg, D., Carter, N., Taylor, D., Di Fiore, L., Whittington, R. (2010). The early lympocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis  compared to infection status. Immunobiology, 215(1), 12-25.
  • Plain, K., Purdie (Williams), A., Begg, D., de Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease. Veterinary Immunology and Immunopathology, 137(1-2), 142-148. [More Information]
  • Begg, D., de Silva, K., Bosward, K., Di Fiore, L., Taylor, D., Jungersen, G., Whittington, R. (2009). Enzyme-linked immunospot: An alternative method for the detection of interferon gamma in Johne's disease. Journal of Veterinary Diagnostic Investigation, 21(2), 187-196.
  • Zhong, L., Di Fiore, L., Taylor, D., Begg, D., de Silva, K., Whittington, R. (2009). Identification of differentially expressed genes in ileum, intestinal lymph node and peripheral blood mononuclear cells of sheep infected with Mycobacterium avium subsp. paratuberculosis using differential display polymerase chain reaction. Veterinary Immunology and Immunopathology, 131(3-4), 177-189. [More Information]
  • Begg, D., Whittington, R. (2008). Experimental animal infection models for Johne's disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. The Veterinary Journal, 176, 129-145.
  • Taylor, D., Zhong, L., Begg, D., de Silva, K., Whittington, R. (2008). Toll-like receptor genes are differentially expressed at the sites of infection during the progression of Johne's disease in outbred sheep. Veterinary Immunology and Immunopathology, 124, 132-151.
  • Begg, D., O'Brien, R., Mackintosh, C., Griffin, F. (2005). Experimental infection model for Johne's disease in sheep. Infection and Immunity, 73(9), 5603-5611.
  • Begg, D., Griffin, F. (2005). Vaccination of sheep against M. paratuberculosis: Immune parameters and protective efficacy. Vaccine, 23(42), 4999-5008.
  • Begg, D., Kemp, R., Griffin, F. (2004). Normal levels of immunocompetence in possums (Trichosurus vulpecula) exposed to different laboratory housing conditions post capture. Immunology and Cell Biology, 82(3), 253-256.

Conferences

  • Begg, D. (2014). Johne’s disease; a Mycobacterial infection of Ruminants. National Institute for Mathematical and Biological Synthesis seminar series, N/A: N/A.
  • de Silva, K., Begg, D., Purdie (Williams), A., Plain, K., Whittington, R. (2013). Comparison Of The Host Immune Response To Gudair® Vaccination And Map Exposure. International Veterinary Immunology Syposium.
  • Begg, D., Whittington, R. (2013). Johne’s disease in sheep. 8th International Sheep Veterinary Congress, Rotorua, New Zealand: New Zealand Veterinary Association Inc.
  • Plain, K., Marsh, B., Begg, D., Galea, F., Waldron, A., Whittington, A., Whittington, R. (2012). A new high-throughput direct faecal PCR test for Johnes diesease. IVVDC 2012, Queensland: N/A.
  • Plain, K., Marsh, I., Begg, D., Galea, F., Waldron, A., Whittington, A., Whittington, R. (2012). A new high-throughput direct faecal PCR test for Johne’s disease. 6th International Veterinary Vaccines and Diagnostics Conference, N/A: N/A.
  • Purdie (Williams), A., Begg, D., de Silva, K., Plain, K., Whittington, R. (2012). Differential gene expression changes associated with sub-clinical Mycobacterium avium subspecies paratuberculosis infection in cattle: a transcriptomic study. Immunology 2012, usa: N/A.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Dhand, N., Whittington, R. (2012). Early biomarkers of resistance and susceptibility to mycobacterial disease. Immunology 2012, usa: N/A.
  • Eppleston, J., Begg, D., Curran, G., Dhand, N., Watt, B., Whittington, R. (2012). Envoronmental survival of MAP across New South Wales. 94th District veterinarian's Conference, Wollongong: District veterinarian's association.
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storage time of blood in interferon gamma assays to diagnose paratuberculosis: combination of IL-7 and IL-12 stimulation. 6th International Veterinary Vaccines and Diagnostics Conference, N/A: N/A.
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storage time of blood in interferon gamma assays to disgnose paratuberculosis: combination of II-7 and II-12 stimulation. 4th European Veterinary Immunology Workshop (EVIW), N/A: N/A.
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storgage time of blood in interferon gamma assay to diagnose paratuberculosis: reporting guidelines. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Whittington, R. (2012). Immune profiles and faecal shedding of Mycobacterium avium paratuberculosis indicate eventual severity of Johne's Disease. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Dukkipati, V., Ridler, A., Buddle, B., Hedgespeth, B., Begg, D., Whittington, R., Murray, A. (2012). Immune response profiles of lambs infected with a lyophilised pure culture seed-stock of mycobacterium avium subspecies paratuberculosis. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). Immunogenicity evaluation of in silico identified MAP recombinant proteins that were upregulated under stress conditions. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Gurung, R., Begg, D., Purdie (Williams), A., Whittington, R. (2012). Immunogenicity evaluation of in silico Mycobacterium avium subsp paratuberculosis recombinant proteins that were upregulated under stress conditions. IVVDC 2012, Queensland: N/A.
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2012). The role of indoleamine 2,3-dioxygenase (IDO) and tryptophan catabolism in paratuberculosis disease progression. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Purdie (Williams), A., Begg, D., de Silva, K., Plain, K., Whittington, R. (2012). Transcriptomic analysis of sub clinical mycobacterium avium subsp.paratuberculosis infection in cattle. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Eppleston, J., Begg, D., Curran, G., Dhand, N., Watt, B., Whittington, R. (2012). Variability in environmental survival of ovine and bovine strains of MAP across climativ zones of NSW. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Begg, D., de Silva, K., Plain, K., Purdie (Williams), A., Whittington, R. (2010). Does a Th1 over Th2 dominance exist in the early stages of Mycobacterium avium subsp. paratuberculosis infections? 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Whittington, R. (2010). Immune correlates of protection and susceptibility to mycobacterial disease. 41st Australasian Society for Immunology Annual Meeting, N/A: N/A.
  • de Silva, K., Begg, D., Kawaji, S., Plain, K., Whittington, R. (2010). Immune profile and faecal shedding of Mycobacterium avium paratuberculosis vary with lesion severity in Johne’s disease. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2010). Immunological characteristics of paratuberculosis as a mycobacterial infection. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2010). Mycobacterial infection – lessons from tuberculosis and paratuberculosis. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Miller, Y., Collins, A., Emery, D., Begg, D., Smits, R., Harvey (Holyoake), P. (2010). Parity of the rearing dam can influence progeny innate immune responses. 21st International Pig Veterinary Society Congress IPVS 2010, Canada: International Pig Veterinary Society.
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2010). Role of IDO and tryptophan catabolism in chronic mycobacterial disease pathogenesis. 41st Australasian Society for Immunology Annual Meeting, N/A: N/A.
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2009). Detection of Mycobacterium avium subspecies paratuberculosis (MAP) using culture from blood during early, subclinical and clinical stages of disease. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Bower (Goldsmith), K., Zhong, L., Kawaji, S., Emery, D., Whittington, R. (2009). Development of an experimental infection model for Johne's disease using a lyophilised pure culture seedstock of Mycobacterium avium subspecies paratuberculosis. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Begg, D., Plain, K., Waldron, A., de Silva, K., Whittington, R. (2009). Development of an Experimental Infection Model in Cattle using a Low Passage Seed Stock of MAP. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Plain, K., Begg, D., Waldron, A., de Silva, K., Whittington, R. (2009). Development of an experimental infection protocol in cattle using a low passage cultured strain of MAP. 10th International Colloquium on Paratuberculosis, USA: University of Minnesota.
  • Miller, Y., Collins, A., Smits, R., Begg, D., Emery, D., Harvey (Holyoake), P. (2009). Effect of dam parity on maternal transfer of specific IgG into colostrum and milk following vaccination with tetanus toxoid. 12th Australasian Pig Science Association Conference APSA 2009, Australia: Australasian Pig Science Association.
  • de Silva, K., Begg, D., Whittington, R. (2009). The early IL-10 response in ovine Johne's disease. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Taylor, D., Zhong, L., Di Fiore, L., Begg, D., de Silva, K., Whittington, R. (2008). Analysis of Toll-like receptor gene expression in Mycobacterium paratuberculosis infected sheep. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Browne, S., de Silva, K., Begg, D., Whittington, R., Emery, D. (2008). Apoptosis of mononuclear cells in experimental and natural ovine Johne's disease. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Bower, K., Begg, D., Di Fiore, L., Taylor, D., Whittington, R. (2008). Culture of M. paratuberculosis from Blood. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Begg, D., Taylor, D., de Silva, K., Di Fiore, L., Whittington, R. (2008). Experimental infection of sheep with M.avium subspecies paratuberculosis: a brief review and introduction to an Australian ovine challenge model. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • de Silva, K., Begg, D., Taylor, D., Di Fiore, L., Whittington, R. (2008). Proliferation of lymphocyte subsets in experimental ovine Johne's disease. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Plain, K., Begg, D., Whittington, R. (2008). Role of IDO in the response to Mycobacterium avium subspecies paratuberculosis infection. Australasian Society for Immunology Conference 2008, Australia: Australasian Society for Immunology.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2008). Seeing spots, developing an IFN-gamma ELISPOT assay to detect ovine M. avium subspecies paratuberculosis infection. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Begg, D., de Silva, K., Whittington, R. (2008). The IFN-g to antibody switch - does it really happen in Mycobacterium paratuberculosis infections? The 38th Australasian Society for Immunology Annual Conference ASI 2008, Australia: Australasian Society for Immunology.
  • Hick, P., Gore, K., Whittington, R., Taylor, D., Begg, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L. (2007). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 3rd National FRDC Aquatic Animal Health Scientific Conference 2007, Australia: Fisheries Research and Development Corporation.
  • Gore, K., Hick, P., Begg, D., Taylor, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L., Whittington, R. (2006). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Gore, K., Hick, P., Begg, D., Taylor, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, J., Whittington, R. (2006). History of viral nervous necrosis outbreaks in farmed barramundi Lates calcarifer from the Northern Territory of Australia. 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Di Fiore, L., Taylor, D., de Silva, K., Bosward, K., Begg, D., Emery, D., Whittington, R. (2006). Identificaiton of differentially expressed genes in uninfected and Mycobacterium paratuberculosis (M.ptb. ) infected sheep. The 8th International Colloquium on Paratuberculosis, N/A: N/A.
  • Di Fiore, L., Taylor, D., de Silva, K., Bosward, K., Begg, D., Emery, D., Whittington, R. (2006). Identification of differentially expressed genes in uninfected and Mycobacterium paratuberculosis (M. ptb.) infected sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Begg, D., Griffin, F. (2006). Immune parameters and vaccine efficacy in Mycobacterium avium subspecies paratuberculosis experimentally infected sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Bosward, K., Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Emery, D., Whittington, R. (2006). Optimisation of the interferon-gamma assay to maximise responses to M. ptb. antigen in sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Hick, P., Gore, K., Taylor, D., Begg, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L., Whittington, R. (2006). Permissivity of the SSN-1 cell line to Lates calcarifer nervous necrosis virus. 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2006). Seeing spots, using the ELISPOT assay to detect M. avium subspecies paratuberculosis infection in sheep. Australasian Society for Immunology Conference 2006, Australia: Australasian Society for Immunology.
  • Bower (Goldsmith), K., Begg, D., Di Fiore, L., Whittington, R. (2005). Detection of Mycobacteria from blood. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • de Silva, K., Begg, D., Di Fiore, L., Taylor, D., Emery, D., Whittington, R. (2005). Early cellular responses in ovine Johne's disease. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Begg, D., Bosward, K., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2005). ELISPOT - new methods for detecting IFN-y. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Bosward, K., Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2005). Manipulation of the Interferon - gamma assay to maximise responses to M. ptb antigen in sheep. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Taylor, D., Gumber, S., de Silva, K., Bower (Goldsmith), K., Di Fiore, L., Begg, D., Whittington, R. (2005). Molecular approaches to studying the host-parasite interaction. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Begg, D., Crosbie, P., Griffin, F. (2003). Ovine Johne's disease: Comparative immunological responses in peripheral blood and gut associated lymphoid tissue. Australasian Society for Immunology Conference 2003, Australia: Australasian Society for Immunology.

2014

  • Gurung, R., Begg, D., Purdie (Williams), A., Whittington, R. (2014). Antigenicity in sheep of synthetic peptides derived from stress-regulated Mycobacterium avium subsp. paratuberculosis proteins and comparison with recombinant protein and complex native antigens. Veterinary Immunology and Immunopathology, 158(1-2), 46-52. [More Information]
  • Gurung, R., Purdie (Williams), A., Whittington, R., Begg, D. (2014). Cellular and humoral immune responses in sheep vaccinated with candidate antigens MAP2698c and MAP3567 from Mycobacterium avium subspecies paratuberculosis. Frontiers in Cellular and Infection Microbiology, 14(Article 93), 1-8. [More Information]
  • Eppleston, J., Begg, D., Dhand, N., Watt, B., Whittington, R. (2014). Environmental Survival of mycobacterium avium subsp. paratuberculosis in Different Climatic Zones of Eastern Australia. Applied and Environmental Microbiology, 80(8), 2337-2342. [More Information]
  • Thirunavukkarasu, S., Plain, K., de Silva, K., Begg, D., Whittington, R., Purdie (Williams), A. (2014). Expression of genes associated with cholesterol and lipid metabolism identified as a novel pathway in the early pathogenesis of Mycobacterium avium subspecies paratuberculosis - infection in cattle. Veterinary Immunology and Immunopathology, 160, 147-157. [More Information]
  • Plain, K., Marsh, I., Waldron, A., Galea, F., Whittington, A., Saunders, V., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2014). High-Throughput Direct Faecal PCR Assay to detect Mycobacterium avium subspecies paratuberculosis in sheep and cattle. Journal of Clinical Microbiology, 52(3), 745-757. [More Information]
  • Gurung, R., Begg, D., Purdie (Williams), A., Bach, H., Whittington, R. (2014). Immunoreactivity of protein tyrosine phosphatase A (PtpA) in sera from sheep infected with Mycobacterium avium subspecies paratuberculosis. Veterinary Immunology and Immunopathology, 160, 129-132. [More Information]
  • Begg, D. (2014). Johne’s disease; a Mycobacterial infection of Ruminants. National Institute for Mathematical and Biological Synthesis seminar series, N/A: N/A.
  • Gurung, R., Begg, D., Purdie (Williams), A., de Silva, K., Bannantine, J., Whittington, R. (2014). Lymphoproliferative and IFN-y responses to stress-regulated Mycobacterium avium subspecies paratuberculosis recombinant proteins. Clinical and Vaccine Immunology, 21(6), 831-837. [More Information]

2013

  • Gurung, R., Begg, D., Purdie (Williams), A., Bannantine, J., Whittington, R. (2013). Antigenicity of Recombinant Maltose Binding Protein-Mycobacterium avium subsp. Paratuberculosis Fusion Proteins with and without Factor Xa Cleaving. Clinical and Vaccine Immunology, 20(12), 1817-1826. [More Information]
  • de Silva, K., Browne, S., Begg, D., Whittington, R., Emery, D. (2013). Apoptosis of lymph node and peripheral blood cells in ovine Johne's disease. Veterinary Immunology and Immunopathology, 156(1-2), 82-90. [More Information]
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Dhand, N., Whittington, R. (2013). Can early host responses to mycobacterial infection predict eventual disease outcomes? Preventive Veterinary Medicine, 112, 203-212. [More Information]
  • de Silva, K., Begg, D., Purdie (Williams), A., Plain, K., Whittington, R. (2013). Comparison Of The Host Immune Response To Gudair® Vaccination And Map Exposure. International Veterinary Immunology Syposium.
  • Whittington, R., Whittington, A., Waldron, A., Begg, D., de Silva, K., Purdie (Williams), A., Plain, K. (2013). Development and validation of a liquid medium (M7H9C) for routine culture of Mycobacterium avium subsp. paratuberculosis to replace modified Bactec 12B medium. Journal of Clinical Microbiology, 51(12), 3993-4000. [More Information]
  • Begg, D., Whittington, R. (2013). Johne’s disease in sheep. 8th International Sheep Veterinary Congress, Rotorua, New Zealand: New Zealand Veterinary Association Inc.
  • Miller, Y., Collins, A., Emery, D., Begg, D., Smits, R., Holyoake, P. (2013). Piglet performance and immunity is determined by the parity of both the birth dam and the rearing dam. Animal Production Science, 53(1), 46-51. [More Information]
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2013). Tissue localisation of Mycobacterium avium subspecies paratuberculosis following artificially induced intracellular and naked bacteraemia. Veterinary Microbiology, 162(1), 112-118. [More Information]

2012

  • Plain, K., Marsh, B., Begg, D., Galea, F., Waldron, A., Whittington, A., Whittington, R. (2012). A new high-throughput direct faecal PCR test for Johnes diesease. IVVDC 2012, Queensland: N/A.
  • Plain, K., Marsh, I., Begg, D., Galea, F., Waldron, A., Whittington, A., Whittington, R. (2012). A new high-throughput direct faecal PCR test for Johne’s disease. 6th International Veterinary Vaccines and Diagnostics Conference, N/A: N/A.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2012). Comparative immunological and microbiological aspects of paratuberculosis as a model mycobacterial infection. Veterinary Immunology and Immunopathology, 148(1-2), 29-47.
  • Purdie (Williams), A., Begg, D., de Silva, K., Plain, K., Whittington, R. (2012). Differential gene expression changes associated with sub-clinical Mycobacterium avium subspecies paratuberculosis infection in cattle: a transcriptomic study. Immunology 2012, usa: N/A.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Dhand, N., Whittington, R. (2012). Early biomarkers of resistance and susceptibility to mycobacterial disease. Immunology 2012, usa: N/A.
  • Plain, K., Begg, D., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Enhancement of the interferon gamma assay to detect paratuberculosis using interleukin-7 and interleukin-12 potentiation. Veterinary Immunology and Immunopathology, 149(1-2), 28-37. [More Information]
  • Eppleston, J., Begg, D., Curran, G., Dhand, N., Watt, B., Whittington, R. (2012). Envoronmental survival of MAP across New South Wales. 94th District veterinarian's Conference, Wollongong: District veterinarian's association.
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2012). Expression of genes associated with the antigen presentation and processing pathway are consistently regulated in early Mycobacterium avium subsp. paratuberculosis infection. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 35(2), 151-162. [More Information]
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storage time of blood in interferon gamma assays to diagnose paratuberculosis: combination of IL-7 and IL-12 stimulation. 6th International Veterinary Vaccines and Diagnostics Conference, N/A: N/A.
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storage time of blood in interferon gamma assays to disgnose paratuberculosis: combination of II-7 and II-12 stimulation. 4th European Veterinary Immunology Workshop (EVIW), N/A: N/A.
  • Begg, D., Plain, K., de Silva, K., Purdie (Williams), A., Whittington, R. (2012). Extension of the storgage time of blood in interferon gamma assay to diagnose paratuberculosis: reporting guidelines. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Whittington, R. (2012). Immune profiles and faecal shedding of Mycobacterium avium paratuberculosis indicate eventual severity of Johne's Disease. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Dukkipati, V., Ridler, A., Buddle, B., Hedgespeth, B., Begg, D., Whittington, R., Murray, A. (2012). Immune response profiles of lambs infected with a lyophilised pure culture seed-stock of mycobacterium avium subspecies paratuberculosis. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). Immunogenicity evaluation of in silico identified MAP recombinant proteins that were upregulated under stress conditions. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Gurung, R., Begg, D., Purdie (Williams), A., Whittington, R. (2012). Immunogenicity evaluation of in silico Mycobacterium avium subsp paratuberculosis recombinant proteins that were upregulated under stress conditions. IVVDC 2012, Queensland: N/A.
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico identification of epitopes in Mycobacterium avium subsp paratuberculosis proteins that were upregulated under stress conditions. Clinical and Vaccine Immunology, 19(6), 855-864. [More Information]
  • Gurung, R., Purdie (Williams), A., Begg, D., Whittington, R. (2012). In silico screened Mycobacterium avium subsp. paratuberculosis (MAP) recombinant proteins upregulated under stress conditions are immunogenic in sheep. Veterinary Immunology and Immunopathology, 149(3-4), 186-196. [More Information]
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2012). The role of indoleamine 2,3-dioxygenase (IDO) and tryptophan catabolism in paratuberculosis disease progression. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Purdie (Williams), A., Begg, D., de Silva, K., Plain, K., Whittington, R. (2012). Transcriptomic analysis of sub clinical mycobacterium avium subsp.paratuberculosis infection in cattle. 11th International Colloquium on Paratuberculosis, N/A: N/A.
  • Eppleston, J., Begg, D., Curran, G., Dhand, N., Watt, B., Whittington, R. (2012). Variability in environmental survival of ovine and bovine strains of MAP across climativ zones of NSW. 11th International Colloquium on Paratuberculosis, N/A: N/A.

2011

  • Kawaji, S., Begg, D., Plain, K., Whittington, R. (2011). A longitudinal study to evaluate the diagnostic potential of a direct faecal quantitative PCR test for Johne's disease in sheep. Veterinary Microbiology, 148(1), 35-44. [More Information]
  • Zhong, L., Taylor, D., Begg, D., Whittington, R. (2011). Biomarker discovery for ovine paratuberculosis (Johne's disease) by Proteomic serum profiling. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(4), 315-326. [More Information]
  • Purdie (Williams), A., Plain, K., Begg, D., de Silva, K., Whittington, R. (2011). Candidate gene and genome-wide association studies of Mycobacterium avium subsp. paratuberculosis infection in cattle and sheep: A review. Comparative Immunology, Microbiology and Infectious Diseases: the international journal for medical and veterinary researchers and practitioners, 34(3), 197-208. [More Information]
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2011). Culture of Mycobacterium avium subspecies paratuberculosis (MAP) from blood and extra-intestinal tissues in experimentally infected sheep. Veterinary Microbiology, 147(1-2), 127-132. [More Information]
  • Begg, D., de Silva, K., Carter, N., Plain, K., Purdie (Williams), A., Whittington, R. (2011). Does a Th1 over Th2 dominancy really exist in the early stages of Mycobacterium avium subspecies paratuberculosis infections? Immunobiology, 216(7), 840-846. [More Information]
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2011). Indoleamine 2,3-Dioxygenase, Tryptophan Catabolism, and Mycobacterium avium subsp. paratuberculosis: a model for Chronic Mycobacterial Infection. Infection and Immunity, 79(9), 3821-3832. [More Information]
  • de Silva, K., Begg, D., Whittington, R. (2011). The interleukin 10 response in ovine Johne's disease. Veterinary Immunology and Immunopathology, 139(1), 10-16. [More Information]

2010

  • Begg, D., de Silva, K., Plain, K., Purdie (Williams), A., Whittington, R. (2010). Does a Th1 over Th2 dominance exist in the early stages of Mycobacterium avium subsp. paratuberculosis infections? 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Bower (Goldsmith), K., Zhong, L., Kawaji, S., Emery, D., Whittington, R. (2010). Experimental infection model for Johne's disease using a lyophilised, pure culture, seedstock of Mycobacterium avium subspecies paratuberculosis. Veterinary Microbiology, 141, 301-311.
  • de Silva, K., Begg, D., Plain, K., Purdie (Williams), A., Kawaji, S., Whittington, R. (2010). Immune correlates of protection and susceptibility to mycobacterial disease. 41st Australasian Society for Immunology Annual Meeting, N/A: N/A.
  • de Silva, K., Begg, D., Kawaji, S., Plain, K., Whittington, R. (2010). Immune profile and faecal shedding of Mycobacterium avium paratuberculosis vary with lesion severity in Johne’s disease. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2010). Immunological characteristics of paratuberculosis as a mycobacterial infection. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Whittington, R., Begg, D., de Silva, K., Plain, K., Purdie (Williams), A. (2010). Mycobacterial infection – lessons from tuberculosis and paratuberculosis. 9th IVIS International Veterinary Immunology Symposium, Amsterdam: Elsevier.
  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2010). Optimisation of culture of Mycobacterium avium subspecies  paratuberculosis from blood samples. Journal of Microbiological Methods, 80, 93-99. [More Information]
  • Bosward, K., Dhand, N., Begg, D., Thomson, P., Emery, D., Whittington, R. (2010). Optimization of a whole blood gamma interferon assay for the detection of sheep infected with mycobacterium avium subspecies paratuberculosis. Journal of Veterinary Diagnostic Investigation, 22(2), 210-217.
  • Begg, D., Whittington, R. (2010). Paratuberculosis in sheep. In Marcel A. Behr and Desmond M Collins. (Eds.), Paratuberculosis: organism, disease, control, (pp. 157-168). Wallingford, UK ; Cambridge, MA: CABI Publishing.
  • Miller, Y., Collins, A., Emery, D., Begg, D., Smits, R., Harvey (Holyoake), P. (2010). Parity of the rearing dam can influence progeny innate immune responses. 21st International Pig Veterinary Society Congress IPVS 2010, Canada: International Pig Veterinary Society.
  • Plain, K., de Silva, K., Earl, J., Begg, D., Purdie (Williams), A., Whittington, R. (2010). Role of IDO and tryptophan catabolism in chronic mycobacterial disease pathogenesis. 41st Australasian Society for Immunology Annual Meeting, N/A: N/A.
  • de Silva, K., Begg, D., Carter, N., Taylor, D., Di Fiore, L., Whittington, R. (2010). The early lympocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis  compared to infection status. Immunobiology, 215(1), 12-25.
  • Plain, K., Purdie (Williams), A., Begg, D., de Silva, K., Whittington, R. (2010). Toll-like receptor (TLR)6 and TLR1 differentiation in gene expression studies of Johne's disease. Veterinary Immunology and Immunopathology, 137(1-2), 142-148. [More Information]

2009

  • Bower (Goldsmith), K., Begg, D., Whittington, R. (2009). Detection of Mycobacterium avium subspecies paratuberculosis (MAP) using culture from blood during early, subclinical and clinical stages of disease. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Bower (Goldsmith), K., Zhong, L., Kawaji, S., Emery, D., Whittington, R. (2009). Development of an experimental infection model for Johne's disease using a lyophilised pure culture seedstock of Mycobacterium avium subspecies paratuberculosis. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Begg, D., Plain, K., Waldron, A., de Silva, K., Whittington, R. (2009). Development of an Experimental Infection Model in Cattle using a Low Passage Seed Stock of MAP. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.
  • Plain, K., Begg, D., Waldron, A., de Silva, K., Whittington, R. (2009). Development of an experimental infection protocol in cattle using a low passage cultured strain of MAP. 10th International Colloquium on Paratuberculosis, USA: University of Minnesota.
  • Miller, Y., Collins, A., Smits, R., Begg, D., Emery, D., Harvey (Holyoake), P. (2009). Effect of dam parity on maternal transfer of specific IgG into colostrum and milk following vaccination with tetanus toxoid. 12th Australasian Pig Science Association Conference APSA 2009, Australia: Australasian Pig Science Association.
  • Begg, D., de Silva, K., Bosward, K., Di Fiore, L., Taylor, D., Jungersen, G., Whittington, R. (2009). Enzyme-linked immunospot: An alternative method for the detection of interferon gamma in Johne's disease. Journal of Veterinary Diagnostic Investigation, 21(2), 187-196.
  • Zhong, L., Di Fiore, L., Taylor, D., Begg, D., de Silva, K., Whittington, R. (2009). Identification of differentially expressed genes in ileum, intestinal lymph node and peripheral blood mononuclear cells of sheep infected with Mycobacterium avium subsp. paratuberculosis using differential display polymerase chain reaction. Veterinary Immunology and Immunopathology, 131(3-4), 177-189. [More Information]
  • de Silva, K., Begg, D., Whittington, R. (2009). The early IL-10 response in ovine Johne's disease. 10th International Colloquium on Paratuberculosis, Minnesota: University of Minnesota.

2008

  • Taylor, D., Zhong, L., Di Fiore, L., Begg, D., de Silva, K., Whittington, R. (2008). Analysis of Toll-like receptor gene expression in Mycobacterium paratuberculosis infected sheep. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Browne, S., de Silva, K., Begg, D., Whittington, R., Emery, D. (2008). Apoptosis of mononuclear cells in experimental and natural ovine Johne's disease. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Bower, K., Begg, D., Di Fiore, L., Taylor, D., Whittington, R. (2008). Culture of M. paratuberculosis from Blood. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Begg, D., Whittington, R. (2008). Experimental animal infection models for Johne's disease, an infectious enteropathy caused by Mycobacterium avium subsp. paratuberculosis. The Veterinary Journal, 176, 129-145.
  • Begg, D., Taylor, D., de Silva, K., Di Fiore, L., Whittington, R. (2008). Experimental infection of sheep with M.avium subspecies paratuberculosis: a brief review and introduction to an Australian ovine challenge model. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • de Silva, K., Begg, D., Taylor, D., Di Fiore, L., Whittington, R. (2008). Proliferation of lymphocyte subsets in experimental ovine Johne's disease. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Plain, K., Begg, D., Whittington, R. (2008). Role of IDO in the response to Mycobacterium avium subspecies paratuberculosis infection. Australasian Society for Immunology Conference 2008, Australia: Australasian Society for Immunology.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2008). Seeing spots, developing an IFN-gamma ELISPOT assay to detect ovine M. avium subspecies paratuberculosis infection. 9th International Colloquium on Paratuberculosis ICP 2007, United States: International Association for Paratuberculosis.
  • Begg, D., de Silva, K., Whittington, R. (2008). The IFN-g to antibody switch - does it really happen in Mycobacterium paratuberculosis infections? The 38th Australasian Society for Immunology Annual Conference ASI 2008, Australia: Australasian Society for Immunology.
  • Taylor, D., Zhong, L., Begg, D., de Silva, K., Whittington, R. (2008). Toll-like receptor genes are differentially expressed at the sites of infection during the progression of Johne's disease in outbred sheep. Veterinary Immunology and Immunopathology, 124, 132-151.

2007

  • Hick, P., Gore, K., Whittington, R., Taylor, D., Begg, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L. (2007). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 3rd National FRDC Aquatic Animal Health Scientific Conference 2007, Australia: Fisheries Research and Development Corporation.

2006

  • Gore, K., Hick, P., Begg, D., Taylor, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L., Whittington, R. (2006). Effect of incubation temperature on the permissivity of the SSN-1 cell line to Australian barramundi nervous necrosis virus (ABNNV). 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Gore, K., Hick, P., Begg, D., Taylor, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, J., Whittington, R. (2006). History of viral nervous necrosis outbreaks in farmed barramundi Lates calcarifer from the Northern Territory of Australia. 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Di Fiore, L., Taylor, D., de Silva, K., Bosward, K., Begg, D., Emery, D., Whittington, R. (2006). Identificaiton of differentially expressed genes in uninfected and Mycobacterium paratuberculosis (M.ptb. ) infected sheep. The 8th International Colloquium on Paratuberculosis, N/A: N/A.
  • Di Fiore, L., Taylor, D., de Silva, K., Bosward, K., Begg, D., Emery, D., Whittington, R. (2006). Identification of differentially expressed genes in uninfected and Mycobacterium paratuberculosis (M. ptb.) infected sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Begg, D., Griffin, F. (2006). Immune parameters and vaccine efficacy in Mycobacterium avium subspecies paratuberculosis experimentally infected sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Bosward, K., Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Emery, D., Whittington, R. (2006). Optimisation of the interferon-gamma assay to maximise responses to M. ptb. antigen in sheep. 8th International Colloquium on Paratuberculosis ICP 2005, United States: International Association for Paratuberculosis.
  • Hick, P., Gore, K., Taylor, D., Begg, D., Schipp, G., Bosmans, J., Humphrey, J., Melville, L., Whittington, R. (2006). Permissivity of the SSN-1 cell line to Lates calcarifer nervous necrosis virus. 2006 Viral Nervous Necrosis International Symposium, Hiroshima, Japan: Japanese Society of Fish Pathology.
  • Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2006). Seeing spots, using the ELISPOT assay to detect M. avium subspecies paratuberculosis infection in sheep. Australasian Society for Immunology Conference 2006, Australia: Australasian Society for Immunology.

2005

  • Bower (Goldsmith), K., Begg, D., Di Fiore, L., Whittington, R. (2005). Detection of Mycobacteria from blood. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • de Silva, K., Begg, D., Di Fiore, L., Taylor, D., Emery, D., Whittington, R. (2005). Early cellular responses in ovine Johne's disease. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Begg, D., Bosward, K., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2005). ELISPOT - new methods for detecting IFN-y. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Begg, D., O'Brien, R., Mackintosh, C., Griffin, F. (2005). Experimental infection model for Johne's disease in sheep. Infection and Immunity, 73(9), 5603-5611.
  • Bosward, K., Begg, D., de Silva, K., Di Fiore, L., Taylor, D., Whittington, R. (2005). Manipulation of the Interferon - gamma assay to maximise responses to M. ptb antigen in sheep. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Taylor, D., Gumber, S., de Silva, K., Bower (Goldsmith), K., Di Fiore, L., Begg, D., Whittington, R. (2005). Molecular approaches to studying the host-parasite interaction. MLA OJD Harvest Year Conference, North Sydney, N.S.W: Meat & Livestock Australia Ltd.
  • Begg, D., Griffin, F. (2005). Vaccination of sheep against M. paratuberculosis: Immune parameters and protective efficacy. Vaccine, 23(42), 4999-5008.

2004

  • Begg, D., Kemp, R., Griffin, F. (2004). Normal levels of immunocompetence in possums (Trichosurus vulpecula) exposed to different laboratory housing conditions post capture. Immunology and Cell Biology, 82(3), 253-256.

2003

  • Begg, D., Crosbie, P., Griffin, F. (2003). Ovine Johne's disease: Comparative immunological responses in peripheral blood and gut associated lymphoid tissue. Australasian Society for Immunology Conference 2003, Australia: Australasian Society for Immunology.

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