Associate Professor Merran Govendir
BVSc (Hons I), PhD, MACVSc, MEd(Higher Education), fHERDSA
Associate Professor, Veterinary Pharmacology Associate Dean of Postgraduate Studies
B14 - Mcmaster Building
The University of Sydney
|Telephone||+61 2 9351 5442|
|Fax||+61 2 9351 3056|
Associate Professor Merran Govendir has focused on conducting clinical projects that have direct relevance to improving animal health. Her recent work has concentrated on clinical pharmacology. She was first investigator to publish a clinical trial in epileptic dogs to ascertain whether the human anticonvulsant drug gabapentin, reduced seizure activity. She was a member of an anaesthesia unit which was the first to publish a clinical trial using the agent sevoflurane in cats and ferrets, establishing sevoflurane as a new and useful agent for fast general anaesthetic inductions in small animals. Her most recent publications involved quantification of the development in resistance of common feline and canine bacterial pathogens to the fluoroquinolone therapeutic drugs and reporting on the susceptibility of Rapidly Growing Mycobacteria spp. (that cause skin diseases in cats and dogs) to the human fluoroquinolone moxifloxacin and the new veterinary registered fluoroquinolone pradofloxacin.
Due to her ability assay concentrations of antibiotic concentrations in biological fluids she was invited to join the Faculty group investigation the treatment of chlamydiosis and cryptococcosis in koalas. With her PhD students, she has found that many drugs given to koalas at the recommended dose rate and dosing frequency are not reaching therapeutic concentrations. She hypothesises that the koala has poor oral drug absorption and that the koala uses it very active liver enzymes (required to detoxify their very toxic Eucalypt diet) to rapidly eliminate many drugs. Preliminary studies also indicate that koalas have very poor oral drug absorption from the gastrointestinal tract. This research will ultimately result in her group making recommendations to improve the dose rates and dosage frequencies of drugs used in koalas.
Teaching and supervision
Veterinary Pharmacology & Toxicology
Aspects of Pharmacy Practice for veterinarians
PhD and master's project opportunities
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