Disorder - Cyclopia

Organ Systems Involved
Nervous/sensory

Alternative disorders described within LIDA

Holoprosenchephaly

Alternative Names
Synophthalmia

Presenting Signs

Cyclopia results when the front part of the foetus’ brain fails to divide normally into two hemispheres. This can be caused by defective genes or by certain toxins. Affected kittens have only one large eye. The nose is typically missing or there is a proboscis (resembles a nose) which is non-functioning and positioned below the large eye. Kittens are generally stillborn or die within a few hours of birth. They may have some primitive reflexes but have no higher brain function.

PubMed References
Cyclopia

Contributor
Kylie Grant